Orthologous genes in OrthoFinder**

Species Gene Description
 mmu-u.4  Pde4a  phosphodiesterase 4A, cAMP specific 
 mmu-r.6  Pde4a  phosphodiesterase 4A, cAMP specific 
 mmu-m.5  Pde4a  phosphodiesterase 4A, cAMP specific 
 mmu-u.4  Pde4c  phosphodiesterase 4C, cAMP specific 
 mmu-u.4  Pde4d  phosphodiesterase 4D, cAMP specific 
 rno-u.3  Pde4d  phosphodiesterase 4D 
 rno-u.3  Pde4b  phosphodiesterase 4B 
 hsa-u.4  PDE4A  phosphodiesterase 4A 
 mcc-u.3  PDE4D  phosphodiesterase 4D 
 mcc-u.3  PDE4A  phosphodiesterase 4A 
 cfa-u.3  PDE4A  phosphodiesterase 4A 
 cfa-u.3  PDE4C  phosphodiesterase 4C 
 gga-u.3  PDE4C  phosphodiesterase 4C 
 gga-u.3  PDE4B  phosphodiesterase 4B 
 dre-u.3  pde4a  phosphodiesterase 4A, cAMP-specific 
 dre-u.3  pde4cb  phosphodiesterase 4C, cAMP-specific b 
 dme-u.3  dnc  dunce 
 sce-u.3  PDE2  3',5'-cyclic-nucleotide phosphodiesterase PDE2 
 spo-u.3  lkh1  dual-specificity 

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Top 50 coexpressed genes to Pde4a (mmu-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 mmu4911   Insulin secretion  3 77 2.82
 mmu4261   Adrenergic signaling in cardiomyocytes  2 152 -
 mmu4014   Ras signaling pathway  2 232 -
 mmu4010   MAPK signaling pathway  2 294 -
 mmu5022   Pathways of neurodegeneration - multiple diseases  3 471 -

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mmu:Pde4a (phosphodiesterase 4A, cAMP specific) External Links;


Show/Hide Columns:          
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID
Other ID CoexPub LINK Target Reference

mmu-u.4
for
Pde4a


mmu-r.6
for
Pde4a


mmu-m.5
for
Pde4a


mmu-u.4
for
Pde4c


mmu-u.4
for
Pde4d


rno-u.3
for
Pde4d


rno-u.3
for
Pde4b


hsa-u.4
for
PDE4A


mcc-u.3
for
PDE4D


mcc-u.3
for
PDE4A


cfa-u.3
for
PDE4A


cfa-u.3
for
PDE4C


gga-u.3
for
PDE4C


gga-u.3
for
PDE4B


dre-u.3
for
pde4a


dre-u.3
for
pde4cb


dme-u.3
for
dnc


sce-u.3
for
PDE2


spo-u.3
for
lkh1

1 Syt3 synaptotagmin III 20981 0 5.6 3.1
3.9
1.6
1.3
2.4
1.6
2.4
1.9
1.9
1.4
2.3
1.8
0.6
0.4
1.7
1.5
0.1
-0.2
1.3
1.0
2.7
2.0
1.8
1.6
3.4
2.5
1.4
1.0
1.0
0.9

0.3
-1.9
2 Dact3 dishevelled-binding antagonist of beta-catenin 3 629378 0 4.7 2.9
3.0
0.2
-0.4
-0.6
-0.5
1.9
0.6
0.9
0.4
0.3


0.1
-0.4
0.2
-0.1



3 Adgrb1 adhesion G protein-coupled receptor B1 107831 0 4.4 1.1
3.8
0.1
-0.6
-0.4
0.2
2.2
-0.4
1.0
0.6
-0.5
0.3
0.5
2.8
0.8



4 Hsf4 heat shock transcription factor 4 26386 0 4.4 3.4
2.5
2.4
0.3
0.1
-0.0
-0.4
-0.5
1.3
0.5
1.9
1.4
1.0
0.3
2.6
0.5
1.1
-0.7
0.8
-0.8
0.1
-0.0
1.0
0.7
-1.0
-1.1
-0.0
-1.0
0.7
-1.5

5 Apba1 amyloid beta (A4) precursor protein binding, family A, member 1 319924 0 4.3 2.6
2.9
-0.3
-0.1
0.8
-0.6
1.5
-0.5
0.7
1.9
-0.4
-0.8
0.5
-0.2
0.3



6 Scn1b sodium channel, voltage-gated, type I, beta 20266 0 4.3 3.5
2.3
0.2
1.0
1.0
0.7
3.4
-0.4
3.8
0.7
1.8
1.7
0.5
2.2
1.1
0.7
-0.7



7 Kcnk3 potassium channel, subfamily K, member 3 16527 0 4.2 2.0
3.2
1.1
-0.6
2.3
-0.3
1.2
0.8
0.1
0.1
0.5
0.2
0.6
0.2
0.9
1.3
0.8
0.8
0.6


0.5
-0.6


8 Mdga1 MAM domain containing glycosylphosphatidylinositol anchor 1 74762 0 4.2 3.9
2.0
-1.6
0.4
0.8
-0.6
0.6
0.4
-0.2
0.2
-0.5
1.1
-0.2
0.2
-1.2



9 Ankrd34a ankyrin repeat domain 34A 545554 0 4.1 3.6
2.2
-0.6
0.7
-0.4
-0.0
2.6
-1.4
1.4




1.0
-1.5



10 Nfic nuclear factor I/C 18029 0 4.1 3.8
2.0
-0.1
-0.5
2.2
1.6
1.2
0.8
1.4
0.9
3.4
3.0
0.7
0.5
2.6
1.5
5.2
3.2
1.0
-0.3
0.6
0.3
0.6
0.3
1.5
0.4
1.3
-0.3
1.3


11 Tbkbp1 TBK1 binding protein 1 73174 0 4.1 3.8
2.0
0.8
0.3
-0.1
-0.0
2.6
0.5
2.8
0.9
1.8
1.0
1.3
1.0
-0.5



12 Them6 thioesterase superfamily member 6 223626 0 4.1 1.9
3.1
1.0
-0.1
-0.3
0.8
0.3
0.3
0.1
0.5
0.1


0.4
0.1
0.3
-0.0
0.5
0.2


13 Slc6a7 solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 240332 0 4.0 2.3
2.7
1.6
0.9
1.0
0.2
1.4
0.6
1.7
-0.6
0.7
0.4
0.6





14 Kcnc4 potassium voltage gated channel, Shaw-related subfamily, member 4 99738 0 3.9 1.9
2.9
2.2
0.6
1.8
1.8
1.9
0.4
0.2
-0.2
2.6
2.3
0.5
0.3
2.0
1.7
1.8
0.6
2.5
0.1
0.5
0.3
1.3
0.3
3.1
1.9
1.1
0.6
1.5
0.5


15 Prkcg protein kinase C, gamma 18752 0 3.9 3.7
1.9
1.2
0.5
3.0
1.8
4.3
2.8
2.4
1.9
2.4
1.8
3.4
3.3
2.1
1.6
4.0
0.6
1.4
1.0
0.1
-0.1
1.2
0.7
2.4
1.7
1.8
1.5
9.1
2.4
-0.8
-0.0
16 Cacnb1 calcium channel, voltage-dependent, beta 1 subunit 12295 0 3.9 2.7
2.4
0.7
0.5
2.2
0.6
1.3
0.7
1.8
0.6
4.1
1.7
0.8
0.4
2.5
1.6
1.4
-0.3
2.6
0.9
2.0
0.7
2.6
1.8
1.7
1.2
3.0
0.5
2.3


17 Zfp385a zinc finger protein 385A 29813 0 3.9 3.4
2.0
-0.1
-1.1
-1.3
0.3
2.4
-0.4
3.1
1.3
0.4
0.1
-0.3
1.9
-0.7
0.5
0.4



18 Kcnc3 potassium voltage gated channel, Shaw-related subfamily, member 3 16504 0 3.9 2.8
2.3
2.2
0.6
1.8
1.8
1.9
0.4
0.2
-0.2
2.6
2.3
0.5
0.3
2.0
1.7
1.8
0.6
2.5
0.1
0.5
0.3
1.3
0.3
3.1
1.9
1.1
0.6
1.5
0.5


19 G6pc3 glucose 6 phosphatase, catalytic, 3 68401 0 3.8 2.5
2.5
1.9
1.8
0.3
0.1
0.5
-1.0
0.4
-1.2
-0.2
-1.1
0.9
-0.8
2.0
-0.1
1.4
-0.7
-0.9
-1.0
1.1
0.1
0.4
-0.4
0.1
-0.1
1.2
-0.1
-1.7

-0.6
20 Mapre3 microtubule-associated protein, RP/EB family, member 3 100732 0 3.8 2.9
2.2
0.2
-0.3
1.2
1.1
1.3
0.4
2.4
0.3
1.6
0.9
3.0
1.8
3.8
2.3
0.9
-1.6
-0.5
-1.5
1.3
-0.4
2.0
1.3
1.6
1.5
0.7
-0.0
-0.6
-0.7
-0.7
-0.5
21 Ano8 anoctamin 8 382014 0 3.8 2.1
2.7
1.4
-0.3
0.5
0.3
1.2
-0.3
-0.7
-0.9
1.5
-0.9
0.7
-0.5
0.8
0.5
1.6
-0.0
1.2
-2.0
3.7
-0.4
2.3
-1.3
0.7
-0.5
0.8
0.4
0.9
0.5
-1.0

22 Apc2 APC regulator of WNT signaling pathway 2 23805 0 3.8 2.4
2.5
0.8
-0.4
0.4
-0.4
1.9
-1.2
-0.2
-0.2
1.6
0.7
1.3
-0.1
1.0
0.2
0.7
0.3
2.0
0.0
1.7
-0.2
-0.0
-1.2
1.4
0.6
-0.5
-1.3
1.2
-0.0


23 Syt5 synaptotagmin V 53420 0 3.8 1.3
3.1
1.6
1.3
2.4
1.6
2.4
1.9
1.9
1.4
2.3
1.8
0.6
0.4
1.7
1.5
0.1
-0.2
1.3
1.0
2.7
2.0
1.8
1.6
3.4
2.5
1.4
1.0
1.0
0.9

0.3
-1.9
24 Chst12 carbohydrate sulfotransferase 12 59031 0 3.8 2.9
2.2
-0.6
-0.2
-0.2
-0.7
2.4
1.0
2.8
1.9
-1.2
-0.7
1.3
1.2
0.4



25 Fam43b family with sequence similarity 43, member B 625638 0 3.6 1.4
2.9
0.8
0.6
0.7
-1.3
-0.2
-0.2
1.1
-1.0
0.9
0.8
1.3
0.9
2.9
-0.1
1.3
0.8
2.2
1.2
0.9
0.7
1.3
0.5
1.9
-1.4
0.4


26 Gpr4 G protein-coupled receptor 4 319197 0 3.6 1.6
2.8
2.0
-1.2
1.6
1.7
1.2


1.8
0.8







27 Mpp2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 50997 0 3.6 3.0
2.0
0.5
0.0
0.3
-0.1
2.3
1.5
0.7
0.3
1.6
-0.0
0.7
-0.5
-0.5
-0.9
1.8
0.1
1.7
-0.3
0.4
-0.1
1.1
-0.3
1.5
1.2
1.4
0.6
0.9


28 Lingo1 leucine rich repeat and Ig domain containing 1 235402 0 3.6 2.4
2.3
-0.4
0.2


2.2
-0.3
0.8


1.6
0.4
4.0
0.2



29 Kcnn1 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 84036 0 3.6 2.5
2.2
2.6
1.7
0.7
-0.7
1.1
0.2
-0.3
-0.3
1.9
0.9
1.2
0.3
1.9
1.5
0.5
-0.6
1.1
-1.6
3.9
3.6
2.1
2.0
2.5
1.7
1.2
0.5
4.3


30 Fndc5 fibronectin type III domain containing 5 384061 0 3.6 2.0
2.5
0.2
0.1
1.3
-0.8
1.6
1.4
1.6
-0.1
1.5
0.5
0.3
1.3
0.2
-0.1
-0.5
-0.2
-0.4
2.7
2.1
1.5
0.1
-0.1
-0.2
0.1
-0.0



31 Bsn bassoon 12217 0 3.5 2.8
2.0
-0.5
0.5
-1.2
-1.6
0.7
-0.9
-0.6
0.1
0.7
0.2
-0.6
0.9
-1.4



32 Csdc2 cold shock domain containing C2, RNA binding 105859 0 3.5 1.5
2.8
0.3
-0.1
-0.2
-1.8
-0.3
0.4
0.2
-0.6
-1.1
-1.2
-0.8
-1.1
-0.2
-0.8
1.2
-0.3
0.9
-0.2
2.1
1.2
0.2
-0.5
-0.2
-0.2
0.2


33 A430046D13Rik Riken cDNA A430046D13 gene 654440 0 3.5 3.6

















34 Gm20544 predicted gene 20544 102636262 0 3.5 3.5

















35 St6galnac6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 50935 0 3.5 4.4
1.1
1.2
0.4
0.7
0.3
1.9
-0.7
1.0
-0.6
0.5
2.5
1.6
1.0
0.6



36 Scaf1 SR-related CTD-associated factor 1 233208 0 3.5 1.7
2.6
-0.0
0.2
-1.6
0.0
1.4
0.7
2.5
2.0
-1.0


1.1
-1.1



37 Rab3a RAB3A, member RAS oncogene family 19339 0 3.5 4.0
1.3
1.2
-0.3
2.2
0.9
1.7
0.9
0.6
-0.1
3.6
1.0
2.2
1.6
2.7
0.4
1.6
-0.2
1.1
-0.2
2.5
-0.2
3.4
1.4
1.4
0.9
1.1
1.0
-0.0

0.6
-0.7
38 Necab3 N-terminal EF-hand calcium binding protein 3 56846 0 3.5 2.6
2.1
0.2
-0.6
0.8
-1.0
0.9
0.8
1.4
-1.3
-0.3
1.4
0.3





39 Kifc2 kinesin family member C2 16581 0 3.5 2.5
2.1
2.3
0.5
0.5
-0.1
1.5
-1.5
0.3
1.5
1.5







40 Coro6 coronin 6 216961 0 3.5 3.2
1.7
2.4
1.0
1.6
0.7
1.2
0.3
0.8
0.2
0.6
0.3
0.2
0.1
2.0
0.7
0.7
0.3
2.0
0.9
2.0
-0.1
2.1
1.5
1.9
0.7
0.7
0.3
2.3
-1.0

41 Diras1 DIRAS family, GTP-binding RAS-like 1 208666 0 3.5 1.2
2.9
-0.6
-0.7
0.9
-0.7
0.6
0.2
0.3
-0.0
2.6
0.0
0.8
0.1
2.1
1.5
2.1
-0.8
2.2
2.0
1.2
-0.0
1.5
0.4
1.1
-0.7
0.8


42 Shisa7 shisa family member 7 232813 0 3.5 1.4
2.7
-0.1
-0.7
-0.1
0.8
0.7
-1.0
-0.8
1.4
0.3







43 Ripor1 RHO family interacting cell polarization regulator 1 75687 0 3.5 4.5
0.9
1.4
-0.4
1.1
-0.2
2.2
1.5
2.4
0.4
3.7
-0.5
1.0
0.2
2.2
0.5
1.8
0.3
1.8
0.2
0.4
-0.1
0.8
0.1
-0.6
-1.4
1.5
-0.2



44 Chst1 carbohydrate sulfotransferase 1 76969 0 3.5 3.1
1.8
-1.5
-0.1
-0.6
1.3
-0.2
-0.8
0.8
-0.6
-0.6
2.7
0.7
1.0
-0.1



45 Fmnl1 formin-like 1 57778 0 3.5 2.4
2.2
2.7
0.5
0.3
0.1
-0.6
-0.7
1.8
0.6
5.1
1.2
0.4
0.2
3.5
0.1
1.2
0.5
-0.1
-0.2
0.7
-0.6
1.1
1.0
0.8
0.5
1.4
0.3
0.8
0.2

46 Ankrd9 ankyrin repeat domain 9 74251 0 3.5 3.1
1.7
0.5
0.8
1.4
0.3
0.8
-0.0
0.8
0.5
1.0
1.0
2.2
0.5
0.1



47 Inpp5j inositol polyphosphate 5-phosphatase J 170835 0 3.4 2.3
2.2
0.9
0.7
-0.1
-0.5
-0.1
-1.1
0.0
-1.7
0.8
0.5
1.1
0.1
1.2
0.5
-0.5
-0.8
1.5
0.6
0.7
0.1
1.0
0.1
0.4
-0.1
0.9
-0.5
-0.6
-1.1


48 Klc2 kinesin light chain 2 16594 0 3.4 3.6
1.4
1.2
1.1
0.7
-0.4
0.3
0.3
0.6
-0.4
1.7
-0.7
1.0
-0.1
3.0
-0.4
1.3
-1.6
0.9
-0.4
0.9
1.1
0.9
-0.4
0.8
-0.8
0.0


49 Syngap1 synaptic Ras GTPase activating protein 1 homolog (rat) 240057 0 3.4 3.4

1.2
0.4
1.6
0.6
1.0
0.3
1.4
0.7
3.0
2.5
0.7
0.1
1.2
0.9
3.1
1.2
2.9
1.3
1.2
0.8
0.5
-0.1
3.4
1.8
1.6
0.9
1.3
1.1
0.4
-1.1
50 Doc2g double C2, gamma 60425 0 3.4 2.3
2.1
1.6
1.3
2.4
1.6
2.4
1.9
1.9
1.4
2.3
1.8
0.6
0.4
1.7
1.5
0.1
-0.2
1.3
1.0
2.7
2.0
1.8
1.6
3.4
2.5
1.4
1.0
1.0
0.9

0.3
-1.9
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