Orthologous genes in OrthoFinder**

Species Gene Description
 mmu-u.4  Clcn2  chloride channel, voltage-sensitive 2 
 mmu-r.6  Clcn2  chloride channel, voltage-sensitive 2 
 mmu-m.5  Clcn2  chloride channel, voltage-sensitive 2 
 hsa-u.4  CLCN2  chloride voltage-gated channel 2 
 mcc-u.3  CLCN2  chloride voltage-gated channel 2 
 cfa-u.3  CLCN2  chloride voltage-gated channel 2 
 gga-u.3  CLCN2  chloride voltage-gated channel 2 
 dre-u.3  clcn2b  chloride channel, voltage-sensitive 2b 
 dre-u.3  clcn2a  chloride channel, voltage-sensitive 2a 
 dme-u.3  ClC-a  Chloride channel-a 
 cel-u.3  clh-3  Chloride channel protein;Chloride channel protein clh-3 

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Top 50 coexpressed genes to Clcn2 (mmu-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 mmu250   Alanine, aspartate and glutamate metabolism  3 34 3.87
 mmu4727   GABAergic synapse  3 81 2.76
 mmu220   Arginine biosynthesis  2 18 2.90
 mmu1522   Endocrine resistance  2 93 -
 mmu564   Glycerophospholipid metabolism  2 98 -

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mmu:Clcn2 (chloride channel, voltage-sensitive 2) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID
Other ID CoexPub LINK Target Reference

mmu-u.4
for
Clcn2


mmu-r.6
for
Clcn2


mmu-m.5
for
Clcn2


hsa-u.4
for
CLCN2


mcc-u.3
for
CLCN2


cfa-u.3
for
CLCN2


gga-u.3
for
CLCN2


dre-u.3
for
clcn2b


dre-u.3
for
clcn2a


dme-u.3
for
ClC-a


cel-u.3
for
clh-3

1 Lzts3 leucine zipper, putative tumor suppressor family member 3 241638 0 5.7 4.9
3.0
1.7
1.2
-0.0
1.1
1.5
0.1
2.3
0.2


2 Sema4g sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G 26456 0 5.5 5.0
2.7
3.1
3.7
1.3
2.0
1.1
0.4
2.5
0.8


3 Shf Src homology 2 domain containing F 435684 0 5.4 4.5
2.9
-0.1
-0.3
1.8
1.1
1.0
0.8
4.0
0.5
0.3
-0.1
1.5
0.6
-0.9
-0.8
4 Chrd chordin 12667 0 5.4 5.2
2.4
1.5
1.5
2.4
1.6
0.4
0.7
0.4

5 Kifc2 kinesin family member C2 16581 0 4.8 5.5
1.8
3.7
1.4
2.5





6 Slc35e2 solute carrier family 35, member E2 320541 0 4.7 4.3
2.3

0.2
1.6
-1.2




7 Dennd6b DENN/MADD domain containing 6B 69440 0 4.7 4.2
2.3
0.4
0.4
-0.9
-0.0
-0.3
-0.1
-0.3
4.9
-1.1
0.7
-0.0
0.2
0.7
8 Abat 4-aminobutyrate aminotransferase 268860 0 4.6 4.1
2.3
-0.1
0.6
-0.5
0.4
4.2
-0.7
1.5
-1.8
9 Apbb3 amyloid beta (A4) precursor protein-binding, family B, member 3 225372 0 4.6 4.5
2.0
0.9
0.4
2.2
-0.5
1.6
1.3


10 Skiv2l superkiller viralicidic activity 2-like (S. cerevisiae) 108077 0 4.4 4.0
2.2
1.6
-0.6
1.5
-0.7
-0.4
-1.2
0.5
0.1
0.5
-0.8
-0.4
-0.6
1.2
0.1
0.9
-0.5
11 Rhbdl1 rhomboid like 1 214951 0 4.4 4.4
2.0
1.7
0.2
0.2
-2.0
1.6
-0.7
1.5
0.1
0.1
0.2
-0.5

12 Zbtb48 zinc finger and BTB domain containing 48 100090 0 4.3 3.3
2.5
2.2
1.2
0.2
0.1
-0.1
0.0
0.3

13 Porcn porcupine O-acyltransferase 53627 0 4.3 3.4
2.4
2.9
2.1
1.6

-0.6
-0.8
1.8
0.3
-1.0
0.5
14 Cyp4f14 cytochrome P450, family 4, subfamily f, polypeptide 14 64385 0 4.2 4.0
2.0
1.2
0.9
1.7
1.3
0.5
0.2
2.7
1.1
1.5
1.1
0.7
-0.5
2.1
2.0
1.4
0.8
15 Bmp1 bone morphogenetic protein 1 12153 0 4.2 3.6
2.2
2.0
0.8
2.1
-0.5
0.4
-0.6
1.1
-0.6
1.2
0.0
1.6
0.4
-1.0
-1.4
-0.2
16 Adck5 aarF domain containing kinase 5 268822 0 4.1 3.5
2.2
2.9
2.0
1.9

0.4
-0.3
-0.3

17 Myo1a myosin IA 432516 0 4.1 3.3
2.3
2.2
-0.5
1.7
-0.1
0.9
0.1
1.2
-0.1
0.7
0.5
0.7
0.3
-0.1

18 Lime1 Lck interacting transmembrane adaptor 1 72699 0 4.1 3.0
2.5
0.8

0.3
0.7
0.5
-0.0
1.9
1.4


19 Rps6kb2 ribosomal protein S6 kinase, polypeptide 2 58988 0 4.1 3.7
2.0
0.4
-0.4
0.4
-1.7
-0.5
-1.4
-0.7
-1.0
2.2
0.5
-0.1
-0.6
0.4
1.3
20 Aqp11 aquaporin 11 66333 0 4.1 4.6
1.5
0.8
1.8

1.2
0.7
-0.7

-1.3
-1.4
21 Tle2 transducin-like enhancer of split 2 21886 0 4.0 3.1
2.3
1.1
0.3
0.2
-0.5
0.9
0.9
1.4
0.8
1.0
-0.2
1.7
0.3
0.8
-1.2
22 Gcdh glutaryl-Coenzyme A dehydrogenase 270076 0 4.0 3.6
2.0
1.4
0.5
-0.9
0.7
1.3
-0.6
1.0
-0.1
-0.4
-0.3
23 Gls2 glutaminase 2 (liver, mitochondrial) 216456 0 4.0 3.3
2.2
0.1
-0.0
0.1
-0.9
-0.1
-0.8
-1.4
3.6
1.2
2.5
0.6
1.6
1.1
0.3
24 Plekha7 pleckstrin homology domain containing, family A member 7 233765 0 4.0 2.7
2.5
1.4
2.2
0.7
2.0
0.5
-0.1
2.2
1.8


25 Hs6st1 heparan sulfate 6-O-sulfotransferase 1 50785 0 3.9 3.6
1.9
0.9
0.5
-0.1
0.5
0.1
-0.2
-1.0
0.5
0.1
0.3
0.2
-0.1
-0.0
26 4933439C10Rik RIKEN cDNA 4933439C10 gene 74476 0 3.9 3.3
2.1








27 Dalrd3 DALR anticodon binding domain containing 3 67789 0 3.9 3.4
2.0
1.4
1.0
-1.0
1.9
-1.7
0.5
-1.4

28 Dgkq diacylglycerol kinase, theta 110524 0 3.9 3.9
1.7
3.1
2.3
0.6
-0.3
2.4
0.2
-0.0
-0.9
29 Klhl17 kelch-like 17 231003 0 3.8 3.9
1.7
3.9
0.8
1.3
2.1
-1.0
-0.0
1.1

30 Aifm3 apoptosis-inducing factor, mitochondrion-associated 3 72168 0 3.8 3.3
2.0
1.8
1.6
0.7
0.7
0.1
-1.8
-0.5
-2.4
-1.2
-0.4
31 Lrrc45 leucine rich repeat containing 45 217366 0 3.8 3.3
2.0
2.3
1.4
1.0
-0.2
0.5
-1.1


32 Thpo thrombopoietin 21832 0 3.8 4.3
1.4








33 Zfp598 zinc finger protein 598 213753 0 3.8 3.3
1.9
1.9
1.4
0.3
-0.9
-0.2
0.0
-0.5
0.9
34 Gpt glutamic pyruvic transaminase, soluble 76282 0 3.7 4.2
1.4
2.8
0.5
2.5
0.9
1.0
0.8
2.1
1.2
0.5
-0.4
2.6
0.6
35 Adam11 a disintegrin and metallopeptidase domain 11 11488 0 3.7 2.9
2.1
2.6
0.6
-0.5
0.6
0.9
1.6


36 Oaf out at first homolog 102644 0 3.7 3.6
1.7
3.1
-1.0
0.6
1.1
-0.3
-0.6
-0.9

37 Tesk2 testis-specific kinase 2 230661 0 3.7 3.5
1.7
0.7
-0.1
1.8
-0.2
1.2
0.7
0.4
-1.0
1.7
-0.0
1.1
0.1
1.6

38 Fam193b family with sequence similarity 193, member B 212483 0 3.6 3.4
1.8
1.5
0.4
0.9
0.5
0.4
-0.9


39 B4galnt3 beta-1,4-N-acetyl-galactosaminyl transferase 3 330406 0 3.6 3.6

2.4
-0.6
2.0
-1.0
-0.9
0.3


40 Adcy6 adenylate cyclase 6 11512 0 3.6 2.9
2.0
2.7
0.8
1.7
1.0
2.3
1.9
0.5
0.1
0.8
0.6
3.0
-0.2
0.5
0.1
41 Pex5 peroxisomal biogenesis factor 5 19305 0 3.6 3.9
1.4
2.5
0.4
0.5
0.2
-0.9
1.0
0.4
0.8
0.6
1.6
1.2
0.3
0.2
42 Pnpla6 patatin-like phospholipase domain containing 6 50767 0 3.6 2.8
2.1
1.1
0.7
0.3
-1.0
-0.1
-0.4
1.2
1.1
1.3
0.3
0.2
-0.1
1.0
2.6
0.3
43 Gm51534 predicted gene, 51534 115486872 0 3.6 3.6









44 Ppox protoporphyrinogen oxidase 19044 0 3.6 4.1
1.3
1.4
1.9
1.5
-1.0
1.6
-1.1
-0.1

45 Ubp1 upstream binding protein 1 22221 0 3.6 3.5
1.6
1.5
0.4
1.5
0.5
1.7
0.3
-0.3
-0.6
2.0
0.6
0.6
-0.3


46 Tedc2 tubulin epsilon and delta complex 2 72016 0 3.6 3.0
1.9
1.4
1.0
0.4

0.6
-1.4


47 Clasrp CLK4-associating serine/arginine rich protein 53609 0 3.5 3.0
1.9
0.8
2.0
1.0

0.1
0.4
0.2
-0.5
48 Fgfrl1 fibroblast growth factor receptor-like 1 116701 0 3.5 3.8
1.4
2.9
1.0
1.6
-0.8
-0.6
-0.7
1.8
1.1
1.7
0.0
49 Tmem25 transmembrane protein 25 71687 0 3.5 3.2
1.7
1.7

1.4



0.8

50 Nrbp2 nuclear receptor binding protein 2 223649 0

2.7
5.0
0.3
1.5
1.6
-0.3
0.1
-1.9


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