Orthologous genes in OrthoFinder**

Species Gene Description
 mmu-u.4   Apex1   apurinic/apyrimidinic endonuclease 1 
 mmu-r.6   Apex1   apurinic/apyrimidinic endonuclease 1 
 mmu-m.5   Apex1   apurinic/apyrimidinic endonuclease 1 
 rno-u.3   Apex1   apurinic/apyrimidinic endodeoxyribonuclease 1 
 hsa-u.4   APEX1   apurinic/apyrimidinic endodeoxyribonuclease 1 
 mcc-u.3   APEX1   apurinic/apyrimidinic endodeoxyribonuclease 1 
 cfa-u.3   APEX1   apurinic/apyrimidinic endodeoxyribonuclease 1 
 gga-u.3   APEX1   apurinic/apyrimidinic endodeoxyribonuclease 1 
 dre-u.3   apex1   APEX nuclease (multifunctional DNA repair enzyme) 1 
 dme-u.3   Rrp1   Recombination repair protein 1 
 cel-u.3   exo-3   DNA-(apurinic or apyrimidinic site) endonuclease 

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Top 50 coexpressed genes to Apex1 (mmu-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 mmu3008   Ribosome biogenesis in eukaryotes  7 78 6.98
 mmu3020   RNA polymerase  2 31 2.43
 mmu3013   Nucleocytoplasmic transport  2 118 -
 mmu230   Purine metabolism  2 133 -
 mmu5166   Human T-cell leukemia virus 1 infection  2 250 -

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mmu:Apex1 (apurinic/apyrimidinic endonuclease 1) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

mmu-u.4
for
Apex1
mmu-r.6
for
Apex1
mmu-m.5
for
Apex1
rno-u.3
for
Apex1
hsa-u.4
for
APEX1
mcc-u.3
for
APEX1
cfa-u.3
for
APEX1
gga-u.3
for
APEX1
dre-u.3
for
apex1
dme-u.3
for
Rrp1
cel-u.3
for
exo-3
1 Nifk nucleolar protein interacting with the FHA domain of MKI67 67949 0 8.7 8.7
 3.8
 6.4
 3.6
 5.3
 3.5
 1.5
 1.7
 0.1
 4.1
2 Grwd1 glutamate-rich WD repeat containing 1 101612 0 8.1 7.7
 3.8
 3.8
 1.5
 1.8
 4.2
1.0
 -1.4
 1.1
3 Rrp15 ribosomal RNA processing 15 homolog 67223 0 7.9 8.5
 3.2
 4.7
 1.0
 3.5
 2.0
 4.1
 0.8
 -0.1
 3.8
4 Cdk4 cyclin-dependent kinase 4 12567 1 7.4 8.0
 2.9
 5.6
0.7
 6.5
0.2
 4.0
1.5
 4.1
0.2
 1.2
 2.6
1.7
 -0.2
5 Eif4a1 eukaryotic translation initiation factor 4A1 13681 0 7.1 8.2
 2.5
 6.1
5.9
 2.2
1.6
 5.0
3.7
 3.9
3.5
 2.2
-0.8
 2.6
2.4
 1.0
0.3
 0.4
0.0
6 Nhp2 NHP2 ribonucleoprotein 52530 0 7.1 7.1
 3.1
 5.1
 2.8
 3.9
 4.1
 2.7
 3.3
 -1.3
 3.0
7 Clns1a chloride channel, nucleotide-sensitive, 1A 12729 0 7.0 6.8
 3.2
 5.3
 5.6
 6.1
 1.2
 1.8
 0.5
 3.6
 0.5
8 Wdr12 WD repeat domain 12 57750 0 7.0 7.9
 2.6
 7.6
 3.6
 4.4
 2.0
 2.9
 1.5
 -0.3
 -0.1
9 Cct3 chaperonin containing Tcp1, subunit 3 (gamma) 12462 0 7.0 7.2
 2.9
 5.1
 3.4
 4.1
 3.6
 2.0
 2.7
 2.1
 0.0
10 Smyd5 SET and MYND domain containing 5 232187 0 6.9 7.0
 2.9
 3.4
 1.7
 5.8
 2.7
 -0.8
 1.0
 -0.8
11 Wdr77 WD repeat domain 77 70465 0 6.9 7.0
 2.9
 5.7
 1.2
 2.1
 3.4
2.9
 2.7
 1.8
 1.4
12 Eif3l eukaryotic translation initiation factor 3, subunit L 223691 0 6.8 6.7
 3.1
 4.0
 7.5
 6.1
 0.2
 0.6
 2.2
 0.5
 -0.6
13 Mrps18b mitochondrial ribosomal protein S18B 66973 0 6.8 6.1
 3.3
 4.1
 3.8
 3.9
 0.3
-0.5
 -1.0
 1.0
14 C1qbp complement component 1, q subcomponent binding protein 12261 0 6.8 6.3
 3.2
 5.1
 3.5
 4.9
 6.3
 2.4
 0.7
 1.0
 1.9
15 Wdr74 WD repeat domain 74 107071 0 6.7 6.9
 2.8
 6.5
 4.9
 1.4
 5.3
1.1
 -2.0
 2.1
16 Ddx56 DEAD box helicase 56 52513 0 6.7 7.1
 2.7
 2.9
 1.8
3.7
0.3
 -1.6
 0.6
17 Gnl3 guanine nucleotide binding protein-like 3 (nucleolar) 30877 0 6.7 7.1
 2.7
 4.9
 2.8
 5.6
 2.9
 3.8


18 Pum3 pumilio RNA-binding family member 3 52874 0 6.6 6.2
 3.2
 4.3
 1.3
 3.0
 2.5
 2.5
 1.7
 -1.2
 -0.1
19 Pa2g4 proliferation-associated 2G4 18813 2 6.5 7.6
 2.2
 4.6
 4.7
 8.4
 3.9
 2.6
 4.5
1.3
 0.3
 1.2
20 Utp4 UTP4 small subunit processome component 21771 0 6.5 6.4
 2.9
 6.5
 5.4
 5.0
 5.2
 4.7
 -0.1
 0.6
 -0.2
21 Srm spermidine synthase 20810 0 6.3 5.7
 3.1
 5.1
 2.8
 3.0
 5.7
 2.4
 2.4
 -0.3
 1.5
22 Fbl fibrillarin 14113 0 6.3 6.6
 2.6
 6.0
0.2
 7.2
0.5
 5.9
-0.5
 4.8
 5.1
 4.3
 -0.6
 3.2
23 Pes1 pescadillo ribosomal biogenesis factor 1 64934 0 6.3 6.4
 2.7
 5.8
 3.3
 3.1
 4.6
 3.0
 1.3
 -0.6
 0.3
24 Nop56 NOP56 ribonucleoprotein 67134 0 6.2 7.1
 2.2
 6.4
 3.6
 3.8
 5.1
 4.6
 1.9
 0.0
 2.4
25 Ttc27 tetratricopeptide repeat domain 27 74196 0 6.2 5.9
 2.9
 3.8
 1.3
 2.6
 3.7
 2.4
 0.8
 0.5
 -0.4
26 Impdh2 inosine monophosphate dehydrogenase 2 23918 0 6.2 6.5
 2.5
 3.9
1.2
 7.0
-1.1
 6.6
-0.2
 2.6
0.4
 3.1
 1.6
0.1
 1.0
 1.0
27 Nop16 NOP16 nucleolar protein 28126 0 6.1 6.4
 2.5
 7.0
 2.8
 5.6
 2.8
 3.3
 2.9
 -1.3
 2.6
28 Prmt1 protein arginine N-methyltransferase 1 15469 0 6.1 6.6
 2.4
 4.7
1.0
 4.0
 6.1
-0.4
 4.5
 -0.3
 4.7
0.2
 2.4
 1.1
29 Cct5 chaperonin containing Tcp1, subunit 5 (epsilon) 12465 0 6.1 7.1
 2.2
 5.2
 2.9
 4.1
 3.7
 2.8
 4.2
 1.7
 -1.4
30 Rpf2 ribosome production factor 2 homolog 67239 0 6.1 6.1
 2.7
 6.3
 2.1
 2.9
 1.6
 2.8
 0.6
 -0.9
 2.1
31 Mrto4 mRNA turnover 4, ribosome maturation factor 69902 0 6.1 6.8
 2.2
 5.3
 2.5
 2.1
 6.6
 2.3
 3.2
 -2.2
 -0.7
32 Ipo4 importin 4 75751 0 6.1 4.8
 3.4
 3.6
 5.6
 2.7
 3.9
 0.2
 2.6
 0.4
0.3
33 Ruvbl1 RuvB-like protein 1 56505 0 6.0 7.0
 2.1
 6.1
 3.4
 4.8
 5.2
 2.0
 4.8
 2.3
 1.3
34 Drg1 developmentally regulated GTP binding protein 1 13494 0 6.0 5.8
 2.8
 3.2
2.9
 4.3
1.6
 2.4
2.3
 2.7
2.0
 1.6
1.2
 1.3
0.5
 1.9
0.6
 2.5
-1.9
35 Noc4l NOC4 like 100608 0 6.0 5.4
 3.0
 4.5
 1.1
 1.5
 4.8
 2.9
 2.2
 -0.5
 0.9
36 Nip7 NIP7, nucleolar pre-rRNA processing protein 66164 0 6.0 6.6
 2.3
 5.3
 2.4
 2.3
 3.2
 3.4
 2.8
 -1.3
 2.1
37 Tsr1 TSR1 20S rRNA accumulation 104662 0 5.9 6.1
 2.5
 6.9
 1.9
 2.4
5.6
 2.4
 -1.4
 0.3
38 Rcc2 regulator of chromosome condensation 2 108911 0 5.9 5.6
 2.8
 6.2
 3.2
 3.3
 3.1
 2.4
 8.5
 5.6
39 Cd3eap CD3E antigen, epsilon polypeptide associated protein 70333 0 5.9 5.8
 2.7
 4.3
 1.5
3.3
0.4

40 Mybbp1a MYB binding protein (P160) 1a 18432 0 5.9 5.9
 2.5
 5.5
 2.3
 2.5
 6.5
 5.2
 2.8
 -0.6
41 Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 108147 0 5.9 6.9
 2.0
 5.6
 6.0
 5.8
 2.5
 -0.4
 2.4
 0.2
 -0.2
42 Polr1e polymerase (RNA) I polypeptide E 64424 0 5.8 5.3
 2.9
 4.2
 4.3
 6.3
 2.3
 1.9
 1.1

43 Prmt5 protein arginine N-methyltransferase 5 27374 0 5.8 6.6
 2.1
 3.9
 7.5
 5.0
 3.3
 2.8
 2.8
 2.2
 1.3
44 Mettl1 methyltransferase like 1 17299 0 5.8 6.0
 2.4
 6.2
 3.2
 2.2
 4.7
0.6
 -1.3
 1.5
45 Ddx18 DEAD box helicase 18 66942 0 5.8 6.5
 2.1
 4.9
 2.2
 2.3
 4.1
 3.9
 1.5
 -0.4
 -1.4
46 Ran RAN, member RAS oncogene family 19384 0 5.8 6.2
 2.3
 4.7
0.7
 4.2
 6.5
 4.8
 1.5
 3.0
 3.5
 3.1
47 Rars arginyl-tRNA synthetase 104458 0 5.8 6.3
 2.2
 4.2
 1.5
 2.9
 -0.0
 2.2
 0.9
 2.2
 -0.2
48 Prpf31 pre-mRNA processing factor 31 68988 0 5.7 6.6
 2.0
 2.5
 2.9
 2.7
 1.8
0.7
 1.5
 1.9
49 Set SET nuclear oncogene 56086 0 5.7 6.1
 2.3
 3.5
 2.7
 3.8
 2.9
0.3
 2.7
 5.4
4.0
 4.3
 3.9
50 Pwp2 PWP2 periodic tryptophan protein homolog (yeast) 110816 0 5.6 4.7
 3.1
 4.4
 0.1
 1.0
 5.2
 4.6
 2.5
 -0.3
 0.9
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