Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4   TYR   tyrosinase 
 hsa-r.6   TYR   tyrosinase 
 hsa-m.7   TYR   tyrosinase 
 hsa-m2.4   TYR   tyrosinase 
 hsa-u.4   DCT   dopachrome tautomerase 
 hsa-u.4   TYRP1   tyrosinase related protein 1 
 mmu-u.4   Dct   dopachrome tautomerase 
 mmu-u.4   Tyrp1   tyrosinase-related protein 1 
 rno-u.3   Dct   dopachrome tautomerase 
 rno-u.3   Tyrp1   tyrosinase-related protein 1 
 cfa-u.3   DCT   dopachrome tautomerase 
 cfa-u.3   TYRP1   tyrosinase related protein 1 
 cfa-u.3   TYR   tyrosinase 
 gga-u.3   TYRP1   tyrosinase related protein 1 
 gga-u.3   DCT   dopachrome tautomerase 
 gga-u.3   TYR   tyrosinase 
 dre-u.3   tyrp1a   tyrosinase-related protein 1a 
 dre-u.3   tyrp1b   tyrosinase-related protein 1b 
 dre-u.3   tyr   tyrosinase 

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Top 50 coexpressed genes to TYR (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa4970   Salivary secretion  4 71 4.22
 hsa350   Tyrosine metabolism  2 32 2.38
 hsa561   Glycerolipid metabolism  2 61 -
 hsa5150   Staphylococcus aureus infection  2 96 -
 hsa4916   Melanogenesis  2 101 -

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hsa:TYR (tyrosinase) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-u.4
for
TYR
hsa-r.6
for
TYR
hsa-m.7
for
TYR
hsa-m2.4
for
TYR
hsa-u.4
for
DCT
hsa-u.4
for
TYRP1
mmu-u.4
for
Dct
mmu-u.4
for
Tyrp1
rno-u.3
for
Dct
rno-u.3
for
Tyrp1
cfa-u.3
for
DCT
cfa-u.3
for
TYRP1
cfa-u.3
for
TYR
gga-u.3
for
TYRP1
gga-u.3
for
DCT
gga-u.3
for
TYR
dre-u.3
for
tyrp1a
dre-u.3
for
tyrp1b
dre-u.3
for
tyr
1 TYRP1 tyrosinase related protein 1 7306 89 8.5 10.4
 3.2
 4.5
 7.6
5.9
 8.5
5.9
 10.8
 10.8
 3.7
 3.7
 4.6
3.9
 4.6
4.3
 4.3
3.9
 7.9
6.9
 7.5
6.9
 7.9
7.5
 14.8
13.0
 17.3
14.8
 10.5
10.0
2 MLANA melan-A 2315 65 8.1 6.1
 9.0
 8.2
 5.6
 5.0
 5.3
 9.1




6.4
 4.4
 7.8
 10.0
 14.0
 8.8
3 DCT dopachrome tautomerase 1638 83 7.6 7.2
 6.4
 6.2
 7.6
5.9
 8.5
5.9
 10.8
 10.8
 3.7
 3.7
 4.6
3.9
 4.6
4.3
 4.3
3.9
 7.9
6.9
 7.5
6.9
 7.9
7.5
 14.8
13.0
 17.3
14.8
 10.5
10.0
4 SERPINA12 serpin family A member 12 145264 0 7.0 6.1
 3.3
 6.2
 3.2
 2.3
 3.9
 2.2










5 HTN3 histatin 3 3347 0 7.0 5.8
 2.3
 6.4














6 MUC7 mucin 7, secreted 4589 0 6.8 8.0
 3.3
 4.0
 2.5
 1.7












7 HTN1 histatin 1 3346 0 6.7 6.4
 1.8
 5.4














8 KRT25 keratin 25 147183 0 6.5 6.9
 1.4
 4.4
 1.0
 1.3
 2.8
1.9
 7.5
7.4
 0.5
 1.4
 1.6
0.4
 1.8
1.4
 1.7
0.2





9 LOC105375436 uncharacterized LOC105375436 105375436 0 6.4 6.5
















10 PAX3 paired box 3 5077 16 6.4 6.0
 5.0
 5.2
 3.1
 1.9
 1.9
 5.1




0.7
-0.0
 0.3
-0.2
 2.0
0.4
 1.7
1.3
 1.0
0.0
 4.1
2.3
11 AADACL2 arylacetamide deacetylase like 2 344752 0 6.2 6.7
 2.8
 4.2
 3.3
0.7
 2.6
2.5
 2.0
-0.4
 0.7
-0.8
 0.3
-0.8
 1.3
-0.7
 0.8
-0.2
 0.7
-0.7
 0.5
-1.3
 1.9
0.5
 1.2
0.5
 1.4
-0.5
 2.7
-0.4
 3.7
-0.4
 4.9
-0.7
12 SLC45A2 solute carrier family 45 member 2 51151 32 6.1 7.3
 3.6
 3.4
 4.0
-0.0
 3.1
-0.4
 6.6
-0.3
 10.8
0.3
 -0.3
-0.4
 -0.1
-0.5
 2.4
-0.4
 2.6
-0.6
 1.9
0.3
 -0.4
-1.0
 -0.7
-0.9
 -0.3
-0.9
 9.6
0.4
 11.3
1.5
 8.9
0.1
13 RPTN repetin 126638 0 6.0 5.3
 2.2
 5.3
 3.3
1.4
 1.2
0.5
 1.1
 1.9
 0.7
 0.5
 0.4
 0.2
 0.3
 -0.9
 -1.0
 0.4
 -0.8
 -0.4
 -1.2
14 TRIM63 tripartite motif containing 63 84676 0 6.0 5.4
 3.5
 5.1
 3.9
 4.7
 0.6
 2.6
 0.3
 0.5
 -0.0
 -0.5
 0.0
 -0.2
 -0.2
 -0.0


15 SERPINB12 serpin family B member 12 89777 0 5.8 5.0
 2.1
 5.3
 3.0
 1.4
 0.1
 1.2




1.0
 -0.6
 1.1


16 PNLIPRP3 pancreatic lipase related protein 3 119548 0 5.8 5.3
 1.7
 4.9
 2.5
1.1
 3.3
2.2
 1.3
0.3
 1.0
0.7
 1.4
1.0
 2.2
1.0
 0.5
0.4
 2.4
1.2
 2.4
1.4
 2.8
0.9
 1.5
0.2
 2.0
2.0


17 LCE2B late cornified envelope 2B 26239 0 5.7 7.0
 1.4
 3.1
 1.6
 1.8












18 ALX1 ALX homeobox 1 8092 0 5.7 6.1
 2.0
 3.9
 2.0
 2.4



2.0
 1.3
 0.9
 1.8
 0.7
 1.3
 0.8
 0.8
 1.2
19 PNLIP pancreatic lipase 5406 0 5.7 5.8
 1.4
 4.2
 2.5
1.1
 3.3
2.2
 1.3
0.3
 1.0
0.7
 1.4
1.0
 2.2
1.0
 0.5
0.4
 2.4
1.2
 2.4
1.4
 2.8
0.9
 1.5
0.2
 2.0
2.0


20 SERPINB13 serpin family B member 13 5275 0 5.7 5.4
 1.8
 4.6
 2.1
1.0
 1.8
1.2
 0.8
0.8
 3.8
2.9
 0.5
0.2
 1.4
1.1
 -0.2
-0.7
 -0.2
-0.6
 0.5
0.1
 1.6
0.9
 0.9
0.6
 1.8
1.1
 1.4
0.2
 1.1
0.3
 1.2
1.1
21 NEUROD6 neuronal differentiation 6 63974 0 5.6 5.6
 1.5
 4.3
 2.3
1.1
 1.5
0.6
 1.1
1.0
 3.0
2.8
 0.6
-0.2
 1.9
0.9


0.2
-0.1
 0.4
0.2
 1.3
0.9
 1.6
-0.3
 1.4
0.9
 2.1
-0.2
22 CASP14 caspase 14 23581 0 5.6 6.3
 2.0
 3.6
 2.4
 1.7



0.5
 1.3
 2.1





23 SLC17A6 solute carrier family 17 member 6 57084 0 5.6 6.1
 1.3
 3.7
 2.2
1.6
 2.2
1.3
 2.3
1.5
 2.7
1.1
 0.2
0.1
 2.9
1.0
 0.2
0.1
 2.8
0.7
 0.4
0.2
 0.1
-0.4
 -0.1
-0.5
 0.2
-1.4
 0.9
-0.4
 0.7
0.5
 1.6
1.3
24 ANKRD30A ankyrin repeat domain 30A 91074 0 5.5 5.5
 1.6
 4.2
 1.4
 1.6












25 SMR3B submaxillary gland androgen regulated protein 3B 10879 0 5.5 7.8
 1.0
 1.8
 1.3
 1.2












26 TECRL trans-2,3-enoyl-CoA reductase like 253017 0 5.4 6.0
 2.1
 3.6
 0.8
0.5
 5.0
-0.5
 1.3
0.9
 2.5
-0.1
 0.5
-0.3
 -0.2
-0.4
 -0.0
-0.1
 1.4
-0.3
 0.8
-0.7
 -0.1
-0.4
 0.3
-0.2
 0.7
0.2
 0.6
-0.2
 1.1
0.5
 0.5
0.5
27 PMP2 peripheral myelin protein 2 5375 0 5.4 4.3
 1.7
 5.2
 3.4
3.1
 1.9
1.7
 1.6
1.0
 2.2
1.6
 1.1
0.7
 3.6
0.7
 1.1
-0.1
 1.0
1.0
 0.5
-0.1
 1.2
0.2
 1.0
0.8
 2.2
1.7
 4.8
2.1
 6.3
3.6
 4.5
1.5
28 DCD dermcidin 117159 0 5.4 5.5
 2.6
 3.9
 1.3
 1.1












29 LOC105372218 uncharacterized LOC105372218 105372218 0 5.3 5.4
















30 F9 coagulation factor IX 2158 0 5.3 5.9
 1.8
 3.4
 1.0
 0.8
 1.6
 0.2
 -0.1
 0.1
 0.2
 -0.1
 0.2
 1.1
 0.2
 0.4
 0.6
-0.0
 -0.3
-0.5
 1.2
0.5
31 STATH statherin 6779 0 5.3 5.3
 1.6
 4.0














32 ASB11 ankyrin repeat and SOCS box containing 11 140456 0 5.3 5.4
 0.9
 3.9
 2.2
1.0
 3.4
2.2
 0.8
0.3
 0.7
-0.8
 -0.0
-1.1
 0.3
-0.4
 0.9
0.4
 0.5
0.4
 1.6
-0.4
 1.3
-0.4
 1.5
0.3
 1.3
-0.0
 0.4
-0.3
 1.0
0.5
 0.4
0.4
33 DSG1 desmoglein 1 1828 0 5.3 4.3
 2.5
 5.0
 3.2
1.0
 3.4
2.0
 3.0
1.6
 4.9
3.7
 0.9
0.6
 1.1
0.2
 0.3
-0.1
 1.4
0.5
 0.3
-0.6
 1.2
1.1
 1.4
0.5
 2.5
0.6
 0.3
-0.4
 0.7
-0.2
 2.7
0.6
34 SI sucrase-isomaltase 6476 0 5.3 4.6
 1.5
 4.6
 0.8
0.4
 3.2
-0.2
 0.9
0.9
 2.4
-0.8
 -0.9
-2.1
 3.3
1.0
 2.3
0.0
 1.5
0.0
 0.7
0.6
 1.3
0.4
 -0.3
-0.7
 -0.2
-0.7
 -0.2
 -0.4
 -0.5
35 PPP1R3A protein phosphatase 1 regulatory subunit 3A 5506 0 5.2 5.4
 2.6
 3.7
 0.6
 2.7
 0.7
 2.3
 0.6
 0.7
 0.8
 2.2
 1.5
 0.5
 0.9
 1.7


36 LCE1A late cornified envelope 1A 353131 0 5.1 7.9
1.2














37 CWH43 cell wall biogenesis 43 C-terminal homolog 80157 0 5.1 4.3
 2.1
 4.7
 2.2
 2.0

-0.8
 0.7


1.2
 1.7
 1.4


38 PMEL premelanosome protein 6490 0 5.1 4.6
 2.4
 4.3
 4.8
 2.7
 6.4
 6.7
 1.1
 2.0
 1.8
 1.2
 4.2
 6.2
 4.9
 5.7
 14.2
7.5
 20.1
10.3
 12.2
4.9
39 CPN1 carboxypeptidase N subunit 1 1369 0 4.9 4.8
 2.2
 3.9
 1.9
 0.9
 0.3
 -1.4
 -0.3
 -0.5


-1.7
 1.1
 -0.9
 -0.6
 -0.2
 -1.0
40 UMOD uromodulin 7369 0 4.9 6.2
 1.0
 2.4
 -0.1
-0.1
 2.0
1.7
 -0.5
-0.6
 0.9
-0.8
 -0.6
-0.9
 0.9
0.2
 1.8
1.5
 2.6
1.7
 1.9
0.5
 -0.0
 -0.4
 -0.2
 0.2
-0.8
 0.9
-0.3
 2.7
0.7
41 MYH1 myosin heavy chain 1 4619 0 4.8 4.7
 1.6
 3.8
 1.8
1.8
 2.4
2.1
 0.5
0.5
 2.7
2.2
 1.1
0.9
 1.3
1.1
 0.9
0.9
 3.7
1.0
 1.6
1.6
 2.3
1.6
 1.6
1.2
 1.0
0.7
 1.3
1.3
 2.6
2.2
 2.6
2.1
42 MYH8 myosin heavy chain 8 4626 0 4.8 5.2
 2.5
 3.3
 1.8
1.8
 2.4
2.1
 0.5
0.5
 2.7
2.2
 1.1
0.9
 1.3
1.1
 0.9
0.9
 3.7
1.0
 1.6
1.6
 2.3
1.6
 1.6
1.2
 1.0
0.7
 1.3
1.3
 2.6
2.2
 2.6
2.1
43 KPRP keratinocyte proline rich protein 448834 0 4.8 5.9
2.5
 1.7
 1.8
 1.3
 4.7










44 CLEC3A C-type lectin domain family 3 member A 10143 0 4.8 4.4
 1.6
 4.0
 0.1
-0.3
 2.0
-1.1
 1.5
-0.2
 5.0
0.2
 1.0
0.4
 0.4
-0.3
 1.1
-0.7
 0.2
-1.0
 1.4
-0.5
 0.9
0.7
 0.6
0.5
 0.6
0.5
 0.5
0.4
 0.9
-0.3
 0.3
-0.1
45 LCE1B late cornified envelope 1B 353132 0 4.8 5.6
 2.8
 2.8














46 LCE2C late cornified envelope 2C 353140 0 4.8 6.9
1.5














47 DSCAM-AS1 DSCAM antisense RNA 1 100506492 0 4.8 4.8
















48 UGT2B10 UDP glucuronosyltransferase family 2 member B10 7365 0 4.7 5.2
3.1
 1.3
1.1
 2.8
2.1
 3.1
2.6
 2.4
1.1
 0.3
0.2
 1.6
0.3
 1.8
-0.2
 2.6
0.8
 1.6
0.7
 0.7
0.3
 0.8
0.3
 1.2
-0.8
 1.7
0.6
 2.4
1.1
 1.2
1.0
49 RAG2 recombination activating 2 5897 0 4.7 4.5
 1.7
 3.8
 0.6
 0.5
 -0.4
 1.4

2.0
 1.5
 1.5
 0.9
 -0.5
 0.2
 0.9
 0.0
 0.7
50 AFM afamin 173 0 4.7 5.1
 1.8
 3.2
 0.4
 0.9
 1.4
 -1.3
 -0.9
 -0.2
 0.4
 1.8
 0.6





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