Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4   PRKDC   protein kinase, DNA-activated, catalytic subunit 
 hsa-r.6   PRKDC   protein kinase, DNA-activated, catalytic subunit 
 hsa-m.7   PRKDC   protein kinase, DNA-activated, catalytic subunit 
 hsa-m2.4   PRKDC   protein kinase, DNA-activated, catalytic subunit 
 mcc-u.3   PRKDC   protein kinase, DNA-activated, catalytic subunit 
 mmu-u.4   Prkdc   protein kinase, DNA activated, catalytic polypeptide 
 rno-u.3   Prkdc   protein kinase, DNA-activated, catalytic subunit 
 cfa-u.3   PRKDC   protein kinase, DNA-activated, catalytic subunit 
 gga-u.3   PRKDC   protein kinase, DNA-activated, catalytic polypeptide 
 dre-u.3   prkdc   protein kinase, DNA-activated, catalytic subunit 

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Top 50 coexpressed genes to PRKDC (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa3013   Nucleocytoplasmic transport  7 96 6.39
 hsa5014   Amyotrophic lateral sclerosis  5 313 2.62
 hsa4120   Ubiquitin mediated proteolysis  4 134 3.16
 hsa3040   Spliceosome  3 127 2.18
 hsa5016   Huntington disease  3 306 -

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hsa:PRKDC (protein kinase, DNA-activated, catalytic subunit) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-u.4
for
PRKDC
hsa-r.6
for
PRKDC
hsa-m.7
for
PRKDC
hsa-m2.4
for
PRKDC
mcc-u.3
for
PRKDC
mmu-u.4
for
Prkdc
rno-u.3
for
Prkdc
cfa-u.3
for
PRKDC
gga-u.3
for
PRKDC
dre-u.3
for
prkdc
1 HUWE1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 10075 2 11.0 11.3
 3.3
 8.0
 7.1
 5.5
4.3
 1.9
 5.4
2 DYNC1H1 dynein cytoplasmic 1 heavy chain 1 1778 0 10.3 8.9
 1.2
 9.2
 6.4
 3.8
 2.9
 3.7
 6.1
 2.5
3 MDN1 midasin AAA ATPase 1 23195 1 9.9 9.4
 3.4
 8.0
 8.1
 8.0
 4.5
 5.7
 4.7
 5.8
4 PRPF8 pre-mRNA processing factor 8 10594 1 9.4 9.2
 2.9
 7.2
 7.6
 3.8
 3.3
 3.1
 2.6
 3.0
5 SNRNP200 small nuclear ribonucleoprotein U5 subunit 200 23020 0 9.3 9.0
 1.5
 7.3
 7.5
 4.2
2.2
 4.4
2.1
 2.3
1.6
 3.7
2.0
 4.0
2.3
6 TRRAP transformation/transcription domain associated protein 8295 27 9.1 8.9
 4.3
 7.1
 6.4
 4.8
 4.4
 3.9
 6.7
 3.7
7 MCM4 minichromosome maintenance complex component 4 4173 8 9.0 8.9
 4.0
 7.0
 5.2
 3.6
 3.4
 5.6
 3.7
 3.0
8 UTP20 UTP20 small subunit processome component 27340 2 8.5 8.8
 2.4
 6.2
 6.2
 4.6
 2.1
 4.3
 3.6
 3.6
9 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 56886 0 8.4 8.1
 3.0
 6.8
 4.8
-0.2
 3.6
2.4
 2.8
1.3
 3.7
1.6
 1.3
-0.3
 3.3
1.5
10 UBR5 ubiquitin protein ligase E3 component n-recognin 5 51366 3 8.4 7.2
 3.9
 7.5
 4.4
 5.1
 5.6
 2.6
 1.8
 1.4
11 HEATR1 HEAT repeat containing 1 55127 0 7.9 7.9
 2.5
 6.0
 5.6
 2.7
 1.2
 3.4
 3.3
 3.5
12 SMC1A structural maintenance of chromosomes 1A 8243 13 7.8 7.9
 2.5
 5.8
 3.8
 2.3
0.4
 4.5
1.2
 1.8
 0.7
0.5
 2.1
0.0
13 NUP155 nucleoporin 155 9631 0 7.8 6.8
 2.4
 6.9
 5.3
 4.1
 3.8
 2.3
 2.6
 2.3
14 UBR4 ubiquitin protein ligase E3 component n-recognin 4 23352 0 7.8 7.5
 1.2
 6.1
 6.4
 5.4
 3.1
 3.4
 3.9
 5.2
15 NUP205 nucleoporin 205 23165 0 7.8 7.3
 3.8
 6.3
 6.5
 3.3
 4.9
 1.6
 5.5
 3.2
16 CKAP5 cytoskeleton associated protein 5 9793 0 7.7 7.4
 3.3
 6.1
 7.4
 2.2
 3.1
 2.8
 2.8
 1.7
17 SUPT16H SPT16 homolog, facilitates chromatin remodeling subunit 11198 1 7.7 7.9
 2.1
 5.6
 4.6
 1.0
 1.8
 1.3
 1.2
 2.8
18 CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 790 0 7.6 7.8
 3.1
 5.5
 7.6
-0.8
 4.3
-0.4
 2.1
0.1
 2.0
-0.9
 1.2
1.2
 2.2
-0.1
19 BIRC6 baculoviral IAP repeat containing 6 57448 0 7.5 6.1
 3.3
 7.2
 5.9
 8.0
 7.2
 6.7
 6.1
 2.1
20 CNOT1 CCR4-NOT transcription complex subunit 1 23019 0 7.4 6.2
 2.1
 6.8
 4.9
 4.2
 4.1
 2.9
 3.0
 2.5
21 GCN1 GCN1 activator of EIF2AK4 10985 1 7.2 6.9
 3.1
 5.8
 5.8
 3.2
 2.5
 2.3
 2.8
 4.7
22 HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 8924 0 7.2 6.1
 3.2
 6.6
 5.5
 6.1
 5.1
 6.7
 3.6
 3.5
23 DHX9 DExH-box helicase 9 1660 0 7.2 7.0
 0.8
 5.6
 6.6
 1.3
 3.6
 2.0
3.2
24 IGF2R insulin like growth factor 2 receptor 3482 0 7.2 6.7
 2.5
 5.9
 2.5
 2.2
 2.8
 1.2
 2.9
 2.2
25 USP9X ubiquitin specific peptidase 9 X-linked 8239 0 7.2 6.8
 0.8
 5.8
 6.2
5.7
 6.4
4.1
 6.1
3.9
 3.5
2.2
 2.4
0.5
 3.0
2.9
26 VPS13D vacuolar protein sorting 13 homolog D 55187 0 7.2 6.7
 2.6
 5.9
 6.1
 6.3
 2.2
 2.3
 4.2
 4.3
27 POLR1A RNA polymerase I subunit A 25885 2 7.2 7.6
 1.8
 5.0
 5.1
 1.8
 1.1
 0.4
 2.2
 1.0
28 VPS13B vacuolar protein sorting 13 homolog B 157680 0 7.1 4.8
 2.6
 7.6
 1.1
 8.0
 4.7
 2.4
 4.1
 2.5
29 SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 6599 1 6.9 7.0
 3.5
 5.0
 5.3
0.5
 1.6
-0.1
 2.5
0.3
 0.2
-0.1
 1.3
1.1
 2.0
0.7
30 EP400 E1A binding protein p400 57634 0 6.9 6.8
 2.2
 5.3
 3.2
 2.7
 3.0
 2.8
 4.0
 4.1
31 SF3B3 splicing factor 3b subunit 3 23450 0 6.9 6.4
 1.5
 5.7
 5.1
 1.8
 1.7
 2.7
 1.5
 1.6
32 URB1 URB1 ribosome biogenesis homolog 9875 0 6.8 6.6
 1.7
 5.3
 3.1
 2.4
 0.9
 1.9
 2.7
 1.8
33 CHD4 chromodomain helicase DNA binding protein 4 1108 0 6.7 6.4
 1.6
 5.4
 5.2
2.0
 2.5
2.3
 2.3
1.2
 1.8
0.5
 1.4
-0.4
 1.6
1.6
34 CLTC clathrin heavy chain 1213 0 6.7 6.1
 1.3
 5.8
 5.3
-0.5
 2.5
 1.8
 2.5
1.2
 3.0
2.8
 2.1
1.8
35 MTOR mechanistic target of rapamycin kinase 2475 0 6.6 6.0
 1.8
 5.6
 6.2
 2.6
 3.9
 1.7
 3.0
 4.8
36 LRPPRC leucine rich pentatricopeptide repeat containing 10128 2 6.5 6.5
 2.6
 5.0
 8.7
 3.5
3.5
 0.2
 1.4
37 NUP188 nucleoporin 188 23511 0 6.5 6.3
 1.1
 5.2
 3.7
 1.8
 2.4
 0.6
 3.8
 2.0
38 ACACA acetyl-CoA carboxylase alpha 31 0 6.5 5.9
 1.6
 5.6
 4.7
-0.1
 2.8
1.1
 1.7
1.3
 2.9
0.2
 2.1
-1.0
 1.4
0.8
39 KPNB1 karyopherin subunit beta 1 3837 1 6.5 6.1
 2.1
 5.3
 3.6
 1.3
 0.0
 1.4
 0.4
 1.2
40 TPR translocated promoter region, nuclear basket protein 7175 2 6.5 7.4
 1.5
 4.0
 3.5
 3.7
 4.6
 2.9
 3.3
 4.3
4.3
41 POLA1 DNA polymerase alpha 1, catalytic subunit 5422 5 6.4 6.1
 3.1
 5.3
 5.9
 4.1
 3.9
 2.0
 2.6
 5.3
42 MYCBP2 MYC binding protein 2 23077 0 6.4 5.6
 1.6
 5.7
 7.0
 5.3
 4.4
 5.6
 4.8
 5.5
43 IPO9 importin 9 55705 0 6.3 6.3
 2.5
 4.8
 4.0
 2.6
 1.8
 2.6
 2.3
 2.5
44 HTT huntingtin 3064 0 6.3 5.8
 1.1
 5.2
 4.2
 5.2
 1.9
 2.6
 4.6
 2.5
45 NCAPD3 non-SMC condensin II complex subunit D3 23310 0 6.1 6.1
 2.1
 4.7
 6.5
 3.5
 2.4
 1.8
 2.4
 5.0
46 IPO5 importin 5 3843 0 6.1 6.0
 2.3
 4.8
 5.6
-0.6
 1.4
0.8
 0.1
0.0
 1.8
1.4
 0.5
 1.1
47 USP34 ubiquitin specific peptidase 34 9736 0 6.1 6.8
 2.2
 3.9
 6.6
 7.0
 6.4
 6.0
 5.4
 3.3
48 RIF1 replication timing regulatory factor 1 55183 0 6.1 5.7
 1.7
 5.0
 2.7
 3.5
 4.0
 4.9
 4.4
 4.2
49 LARS1 leucyl-tRNA synthetase 1 51520 0 6.1 5.6
 2.4
 5.0
 6.2
 3.5
 2.6
 2.9
 2.6
 1.9
50 PARP1 poly(ADP-ribose) polymerase 1 142 58 6.0 6.1
 2.4
 4.4
 4.5
 2.4
 2.4
 1.0
 2.2
 3.9
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