Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4   ECSIT   ECSIT signaling integrator 
 hsa-r.6   ECSIT   ECSIT signaling integrator 
 hsa-m.7   ECSIT   ECSIT signaling integrator 
 hsa-m2.4   ECSIT   ECSIT signaling integrator 
 mcc-u.3   ECSIT   ECSIT signaling integrator 
 mmu-u.4   Ecsit   ECSIT signalling integrator 
 rno-u.3   Ecsit   ECSIT signaling integrator 
 cfa-u.3   ECSIT   ECSIT signaling integrator 
 dre-u.3   ecsit   ECSIT signaling integrator 
 dme-u.3   ECSIT   ECSIT 
 cel-u.3   Y17G9B.5   Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial 

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Top 50 coexpressed genes to ECSIT (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa5208   Chemical carcinogenesis - reactive oxygen species  6 192 4.64
 hsa5016   Huntington disease  6 263 3.89
 hsa5010   Alzheimer disease  6 334 3.33
 hsa5022   Pathways of neurodegeneration - multiple diseases  6 408 2.88
 hsa190   Oxidative phosphorylation  5 110 4.72

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hsa:ECSIT (ECSIT signaling integrator) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-u.4
for
ECSIT
hsa-r.6
for
ECSIT
hsa-m.7
for
ECSIT
hsa-m2.4
for
ECSIT
mcc-u.3
for
ECSIT
mmu-u.4
for
Ecsit
rno-u.3
for
Ecsit
cfa-u.3
for
ECSIT
dre-u.3
for
ecsit
dme-u.3
for
ECSIT
cel-u.3
for
Y17G9B.5
1 NDUFB7 NADH:ubiquinone oxidoreductase subunit B7 4713 0 8.0 7.0
 3.5
 7.1
 4.1
 3.1
 6.2
 5.7
 0.7
 2.5
 1.5
2 ALKBH7 alkB homolog 7 84266 0 7.9 7.8
 3.1
 6.0
 6.0
 2.6
 1.0
 6.0
 3.6
 3.1
 1.9
3 DDX49 DEAD-box helicase 49 54555 0 7.8 7.4
 3.3
 6.2
 3.0
 4.2
 2.5
 6.1
 1.0
 2.0
 0.2
4 UBXN6 UBX domain protein 6 80700 0 7.5 8.4
 3.1
 4.8
 3.8
 1.3
 -0.1
 0.5
 -1.4
1.7
5 ATP5F1D ATP synthase F1 subunit delta 513 0 7.2 7.1
 3.6
 5.5
 8.5
 3.8
 5.7
 7.3
 1.8
 2.8
 1.8
6 TIMM44 translocase of inner mitochondrial membrane 44 10469 0 7.0 7.5
 4.1
 4.8
 5.7
 4.1
 3.5
 6.3
 5.8
 1.5
 1.9
7 MRPL38 mitochondrial ribosomal protein L38 64978 0 6.9 6.9
 1.7
 5.3
 6.0
 4.7
 8.9
 6.1
 2.9
 6.6
 -0.3
8 VPS51 VPS51 subunit of GARP complex 738 0 6.9 6.6
 3.7
 5.4
 4.0
 -0.1
 1.8
-0.4
 0.6
 1.7
 1.4
 -0.9
9 MCRIP2 MAPK regulated corepressor interacting protein 2 84331 0 6.9 6.4
 2.3
 5.7
 5.3
2.3
 5.1
-0.7
 4.5
-1.4
 3.2
-0.0
 2.8
0.4
 0.1
-1.1
10 BABAM1 BRISC and BRCA1 A complex member 1 29086 0 6.8 7.2
 2.7
 4.8
 2.6
 4.0
 0.2
 3.6
 -0.2

11 ELOF1 elongation factor 1 homolog 84337 0 6.7 7.8
 3.3
 4.0
 1.7
 1.3
 -0.7
 3.7
 0.2
 -0.1
 1.0
12 GADD45GIP1 GADD45G interacting protein 1 90480 0 6.7 6.0
 2.5
 5.8
 5.3
 2.6
 4.1
 7.1
 4.6

13 EIF3G eukaryotic translation initiation factor 3 subunit G 8666 0 6.6 7.3
 4.2
 4.3
 3.4
 1.6
 1.2
 4.2
 -0.9
 1.3
-0.5
 1.8
14 CCDC124 coiled-coil domain containing 124 115098 0 6.6 8.0
 2.7
 3.5
 4.4
 2.7
 1.3
 5.0
 2.8
 3.0
 2.8
15 THAP4 THAP domain containing 4 51078 0 6.6 6.8
 2.4
 4.7
 4.2
 2.3
 4.7
 4.4
 0.6
1.6
0.6
16 TIMM13 translocase of inner mitochondrial membrane 13 26517 0 6.5 5.9
 2.5
 5.6
 6.4
 2.3
 2.9
 4.1
 5.8
 2.2
-0.2
 -0.3
17 ARMC6 armadillo repeat containing 6 93436 0 6.5 6.2
 2.5
 5.2
 2.0
 2.9
 -1.0
 2.6
 -0.1
 -0.1
18 QTRT1 queuine tRNA-ribosyltransferase catalytic subunit 1 81890 0 6.5 7.2
 2.9
 4.2
 3.3
 1.2
 -0.3
 3.6
 2.9
 0.9
 1.8
19 MRPL54 mitochondrial ribosomal protein L54 116541 0 6.5 5.8
 3.3
 5.5
 1.4
 1.1
 2.8
 2.5
 2.6
 5.2
 -0.6
20 RAD23A RAD23 homolog A, nucleotide excision repair protein 5886 0 6.4 7.0
 3.4
 4.3
 4.3
-0.7
 4.2
0.1
 2.4
0.5
 5.8
-0.2
 -0.1
-0.4
 -0.0
-0.1
 0.9
21 YJU2 YJU2 splicing factor homolog 55702 0 6.4 6.9
 4.0
 4.3
 3.3
 1.4
 1.0
 1.0
 1.5
 3.1
 5.6
22 DMAC2 distal membrane arm assembly component 2 55101 0 6.4 7.4
 4.2
 3.8
 1.3
 4.1
 4.7
 5.1
 2.7
 5.8
 1.9
23 MYG1 MYG1 exonuclease 60314 0 6.3 7.5
 3.1
 3.6
 4.2
 1.4
 2.2
 4.6
 0.9
 2.7
 1.7
24 SARS2 seryl-tRNA synthetase 2, mitochondrial 54938 0 6.3 6.1
 3.1
 5.0
 4.4
3.4
 2.5
 2.5
 6.5
 0.7
25 DHPS deoxyhypusine synthase 1725 0 6.2 6.3
 3.9
 4.6
 3.5
 2.9
 0.5
 6.0
 2.6
 5.0
 0.3
26 MRPL4 mitochondrial ribosomal protein L4 51073 0 6.1 5.0
 3.8
 5.7
 3.9
 6.8
 4.1
 7.7
 3.1
 7.8
 0.3
27 RPUSD4 RNA pseudouridine synthase D4 84881 0 6.1 5.3
 2.4
 5.4
 1.2
 1.5
 3.1
 2.5
 2.3

28 MAP2K7 mitogen-activated protein kinase kinase 7 5609 0 6.0 7.2
 2.1
 3.4
 0.7
 0.1
 0.9
 1.2
 0.1
 -1.2
 -1.8
29 CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 8192 0 6.0 5.9
 3.0
 4.7
 4.6
 5.6
 6.5
 7.1
 4.9
 0.8
 1.2
30 EIF2A eukaryotic translation initiation factor 2A 83939 0 6.0 5.1
 2.6
 5.5
 3.7
 0.8
 1.5
 -0.2
 0.2
 -0.2
 0.9
31 NDUFV1 NADH:ubiquinone oxidoreductase core subunit V1 4723 0 6.0 6.7
 2.1
 3.8
 8.5
 7.1
 8.7
 6.4
 3.1
 3.1
0.3
 1.1
32 MRPS2 mitochondrial ribosomal protein S2 51116 0 5.9 6.1
 2.9
 4.3
 6.4
 2.7
 2.5
 4.3
 4.0
 5.8
 0.5
33 USE1 unconventional SNARE in the ER 1 55850 0 5.9 7.0
 3.2
 3.3
 4.0
 0.4
 0.1
 0.9
 2.3
 0.5
 2.7
34 HSPBP1 HSPA (Hsp70) binding protein 1 23640 0 5.8 5.9
 3.3
 4.4
 3.3
 2.5
 0.5
 3.6
 0.7
 1.7
35 MAF1 MAF1 homolog, negative regulator of RNA polymerase III 84232 0 5.7 5.4
 2.8
 4.7
0.7
 0.1
 0.0
 0.9
-1.4
 -0.2
 3.3
36 AIP aryl hydrocarbon receptor interacting protein 9049 0 5.7 6.0
 2.7
 4.1
 3.7
-0.4
 2.0
-1.3
 1.6
-0.8
 0.9
 -0.5
-1.0
 1.4
 1.1
37 XAB2 XPA binding protein 2 56949 0 5.7 5.9
 2.6
 4.1
 2.2
 2.1
 3.0
 3.4
 1.0
 1.5
 0.5
38 ILVBL ilvB acetolactate synthase like 10994 0 5.7 5.7
 3.0
 4.2
 4.9
 0.5
 2.1
 4.1
 0.1
-0.6
39 WDR18 WD repeat domain 18 57418 0 5.7 6.0
 3.6
 4.0
 3.0
 3.1
 5.0
 3.3
 3.8
 3.5
 0.7
40 TRAPPC5 trafficking protein particle complex subunit 5 126003 0 5.6 5.5
 2.7
 4.3
 4.9
 1.9
 0.5
 3.3
 0.9
 -0.8
 1.4
41 GTPBP6 GTP binding protein 6 (putative) 8225 0 5.5 6.1
3.6
 4.4
 0.4
 1.3
 1.6
 0.7
1.2
42 PGLS 6-phosphogluconolactonase 25796 0 5.5 5.5
 2.2
 4.3
 4.1
 0.2
 0.5
 2.5
 2.3
 0.7
 0.5
43 CYC1 cytochrome c1 1537 0 5.5 4.9
 2.3
 4.8
 5.8
 5.8
 6.3
 6.5
 3.3
 3.7
0.7
 1.6
44 MVB12A multivesicular body subunit 12A 93343 0 5.5 5.5
 1.4
 4.1
 1.7
 1.9
 0.5
 1.8
 -1.3

45 MRPL34 mitochondrial ribosomal protein L34 64981 0 5.5 5.3
 1.9
 4.3
 5.3
 2.6
 3.3
 5.1
 3.2
 3.3
46 EEF2 eukaryotic translation elongation factor 2 1938 0 5.5 6.0
 2.7
 3.6
 1.3
 1.3
 0.2
 0.8
 0.5
0.3
 0.4
 0.2
47 DUS3L dihydrouridine synthase 3 like 56931 0 5.4 6.2
 2.4
 3.4
 3.5
 2.7
 0.4
 4.4
 0.3
 2.1
 -0.3
48 UQCRC1 ubiquinol-cytochrome c reductase core protein 1 7384 0 5.4 5.0
 3.0
 4.5
 3.8
2.9
 8.1
4.3
 7.9
3.8
 8.7
2.4
 3.7
3.4
 2.1
 1.6
49 TMED1 transmembrane p24 trafficking protein 1 11018 0 5.4 6.0
 2.7
 3.4
 2.6
-0.6
 2.7
0.8
 1.2
-0.5
 2.6
-0.3
 3.6
0.6
 0.6
0.2
 0.1
50 TUFM Tu translation elongation factor, mitochondrial 7284 0


5.8
 5.1
 9.6
 5.3
 4.7
 5.0
3.1
 3.4
1.2
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