Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4   CPA4   carboxypeptidase A4 
 hsa-r.6   CPA4   carboxypeptidase A4 
 hsa-m.7   CPA4   carboxypeptidase A4 
 hsa-m2.4   CPA4   carboxypeptidase A4 
 mcc-u.3   CPB2   carboxypeptidase B2 
 mmu-u.4   Cpa4   carboxypeptidase A4 
 gga-u.3   CPA5   carboxypeptidase A5 
 gga-u.3   CPA6   carboxypeptidase A6 
 gga-u.3   CPO   carboxypeptidase O 
 dre-u.3   cpb2   carboxypeptidase B2 (plasma) 
 dre-u.3   cpo   carboxypeptidase O 
 dme-u.3   CG2915   uncharacterized protein 
 dme-u.3   CG4017   uncharacterized protein 
 cel-u.3   Y59C2A.1   Peptidase_M14 domain-containing protein 
 cel-u.3   W01A8.6   Peptidase_M14 domain-containing protein 
 cel-u.3   T06A4.3   Peptidase_M14 domain-containing protein;ShKT domain-containing protein 
 sce-u.3   ECM14   putative metallocarboxypeptidase 

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Top 50 coexpressed genes to CPA4 (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa4010   MAPK signaling pathway  4 263 2.10
 hsa4972   Pancreatic secretion  3 87 2.65
 hsa4974   Protein digestion and absorption  3 87 2.65
 hsa4014   Ras signaling pathway  2 232 -
 hsa4151   PI3K-Akt signaling pathway  2 354 -

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hsa:CPA4 (carboxypeptidase A4) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-u.4
for
CPA4
hsa-r.6
for
CPA4
hsa-m.7
for
CPA4
hsa-m2.4
for
CPA4
mcc-u.3
for
CPB2
mmu-u.4
for
Cpa4
gga-u.3
for
CPA5
gga-u.3
for
CPA6
gga-u.3
for
CPO
dre-u.3
for
cpb2
dre-u.3
for
cpo
dme-u.3
for
CG2915
dme-u.3
for
CG4017
cel-u.3
for
Y59C2A.1
cel-u.3
for
W01A8.6
cel-u.3
for
T06A4.3
sce-u.3
for
ECM14
1 SERPINB7 serpin family B member 7 8710 0 8.1 6.7
 4.1
 7.5
3.4










2 CPA2 carboxypeptidase A2 1358 5 6.5 8.7
 1.8
 2.6
 1.1
 3.4
1.0
 10.4
7.5
 0.2
-0.1
 2.4
2.3
 2.0
1.1
 2.2
2.2
 1.3
0.6
 1.8
1.1
 4.9
1.4
 4.9
3.7
 5.2
5.0
3 KRT80 keratin 80 144501 0 5.7 5.2
 2.9
 4.8
 0.3
 2.0
 0.4
 -0.3
 0.8







4 PSG5 pregnancy specific beta-1-glycoprotein 5 5673 0 4.9 4.8
 3.6
 3.8
 1.9
1.0
 2.9
2.8










5 MEST mesoderm specific transcript 4232 0 4.8 5.2
 2.3
 3.3
 -0.5
 2.9
 1.3
 -0.1
 0.8
 0.3
 -0.5





6 ANKRD1 ankyrin repeat domain 1 27063 0 4.6 4.6
 1.4
 3.4
 1.1
 1.1
 -0.2
 -0.7
 -0.2
 -0.7
 0.5





7 MYPN myopalladin 84665 0 4.6 4.2
 3.3
 3.8
 -0.7
 1.5
 0.5
 -0.1
 -0.5
 0.7
 -0.1





8 CMKLR2 chemerin chemokine-like receptor 2 2825 0 4.3 3.2
 1.5
 4.3
 0.5
0.5
 -1.7
 -0.0
 1.2
 -1.2





9 TMEM40 transmembrane protein 40 55287 0 4.3 3.3
 1.4
 4.2
 -0.4
 2.3
 1.5
 -0.7
 0.1







10 NLRP10 NLR family pyrin domain containing 10 338322 0 4.3 4.1
 2.6
 3.4
2.2










11 SH3RF2 SH3 domain containing ring finger 2 153769 0 4.2 3.1
 2.2
 4.2
 -0.5
 1.7
 -0.1
 -1.2
 0.3







12 ANXA8L1 annexin A8 like 1 728113 0 4.1 3.6
3.7
 0.1
 0.5
 -0.1
 0.2
 -0.0

-0.6
 -0.7



13 TGFB2 transforming growth factor beta 2 7042 0 4.1 3.6
 2.1
 3.7
 -1.8
 -0.1
 -0.9
 0.3
 0.1
 0.8
 0.3





14 CPA1 carboxypeptidase A1 1357 0 4.1 5.8
 0.6
 1.5
 1.1
 3.4
1.0
 10.4
7.5
 0.2
-0.1
 2.4
2.3
 2.0
1.1
 2.2
2.2
 1.3
0.6
 1.8
1.1
 4.9
1.4
 4.9
3.7
 5.2
5.0
15 BDNF brain derived neurotrophic factor 627 0 4.1 2.6
 2.1
 4.5
 0.1
 -0.2
 0.5
 -0.8
 0.1
 -0.2
 0.1





16 KRT75 keratin 75 9119 0 4.0 4.2
 2.3
 2.9
 1.8
0.6
 8.9
6.8
 1.9
1.6
 1.1
0.7
 1.4
1.3
 0.5
0.4
 3.5
0.7





17 TENM2 teneurin transmembrane protein 2 57451 0 4.0 3.1
 0.8
 4.0
 2.0
0.5
 2.0
0.9
 0.8
0.5
 1.6
1.1
 0.6
-0.4
 0.5
-0.1
 -0.2
-0.2
 0.8
0.1
 -0.4
-0.6
 0.3
 -0.1
 0.1
18 COPG2IT1 COPG2 imprinted transcript 1 53844 0 3.9 4.0
 1.5













19 SBSN suprabasin 374897 0 3.9 4.2
 2.4
 2.6
2.4










20 FAM25A family with sequence similarity 25 member A 643161 0 3.9 3.9

0.0
 1.7










21 TUFT1 tuftelin 1 7286 0 3.8 3.3
 1.5
 3.4
 -1.3
 0.8
 0.6
 -0.7
 0.5
 -0.9
 0.3





22 DKK1 dickkopf WNT signaling pathway inhibitor 1 22943 0 3.8 3.6
 1.6
 3.1
 0.4
 1.1
 -1.3
 0.2
 0.0
 -0.4
-0.5
 1.2
0.5





23 PADI1 peptidyl arginine deiminase 1 29943 0 3.8 3.8
 1.6
 2.9












24 LOC105374003 uncharacterized LOC105374003 105374003 0 3.8 3.8














25 CCDC80 coiled-coil domain containing 80 151887 0 3.7 3.0
 1.9
 3.5
 -1.2
 0.0
 0.3
 0.6
 -0.1
 0.7
 0.4





26 GPRC5A G protein-coupled receptor class C group 5 member A 9052 0 3.7 3.1
 2.6
 3.4
 -0.7
 -0.3
 0.1
 1.1
 0.3







27 TGM5 transglutaminase 5 9333 0 3.7 3.6
 2.0
 2.9












28 RPTN repetin 126638 0 3.7 3.9
 2.0
 2.5
 -0.4
 -0.4
 -0.7
 -0.5
 0.9
 0.6
 -0.0





29 SERPINB13 serpin family B member 13 5275 0 3.7 3.3
 2.3
 3.2
 1.5
1.2
 7.7
6.5
 1.4
0.8
 1.1
0.4
 1.2
0.9
 0.9
0.7
 2.7
2.6
 1.8
0.5
 0.9
0.9
 4.0
1.2
 1.1
1.0
 0.6
30 FGF1 fibroblast growth factor 1 2246 0 3.7 3.0
 1.9
 3.4
 0.5
 -1.0
 -0.4
 -0.4
 -1.5







31 EVA1A eva-1 homolog A, regulator of programmed cell death 84141 0 3.6 2.7
 2.2
 3.7
 -0.1
 0.7


-0.4
 -0.3





32 FLNC filamin C 2318 0 3.6 3.0
 1.5
 3.4
 -0.2
-0.5
 1.3
0.2
 0.1
-0.5
 -0.3
-1.4
 1.0
-0.6
 1.0
0.6
 0.7
0.1
 0.4
 -0.3



33 MPP4 membrane palmitoylated protein 4 58538 0 3.6 2.8
 1.8
 3.6
 0.1
 -0.4
 -0.3
 0.2
 -0.2







34 SERPINB12 serpin family B member 12 89777 0 3.6 3.7
 2.0
 2.7
4.3
 -0.4
 0.5
 -1.3







35 LINC00842 long intergenic non-protein coding RNA 842 643650 0 3.6 3.6
 2.9













36 COL12A1 collagen type XII alpha 1 chain 1303 0 3.6 3.6
 1.1
 2.7
 0.3
 1.9
 -0.8
 0.3
 -0.0
 -0.4
 0.6





37 PRR9 proline rich 9 574414 0 3.5 3.6
 2.2

5.7










38 HSPB8 heat shock protein family B (small) member 8 26353 0 3.5 3.2
 1.8
 3.1
 0.1
 0.1
 -0.6
 -1.2
 -0.7
 0.6
 -0.8





39 BNC1 basonuclin 1 646 0 3.5 4.1
 1.8
 2.1
 1.3
0.1
 2.7
1.3
 0.8
-0.6
 1.1
-0.4
 -0.3
-0.8
 1.3
0.7
 0.8
0.5
 -0.9
-1.2
 -0.1
-0.5
 -0.6
 0.5
 0.1
40 DIO2 iodothyronine deiodinase 2 1734 0 3.5 2.8
 1.6
 3.4
 -0.5
 1.2
 -0.7
 1.0
 -0.2
 0.2
 -1.5





41 ARHGAP29 Rho GTPase activating protein 29 9411 0 3.5 2.9
 2.3
 3.3
 0.2
0.2
 -0.4
-1.1
 -0.1
-1.3
 0.4
-0.9
 0.5
-0.4
 -0.3
-0.8
 -0.3
-0.4

0.7
 -0.4
 -1.0
42 LINP1 lncRNA in non-homologous end joining pathway 1 108570035 0 3.5 3.6














43 SRPX2 sushi repeat containing protein X-linked 2 27286 0 3.5 3.5
 1.3
 2.7
 -0.5
 0.9
 -0.0
 -0.2
 -1.1
 0.8
 0.9





44 MARCHF4 membrane associated ring-CH-type finger 4 57574 0 3.5 2.5
 1.2
 3.7
 0.2
 -0.3
 0.2
 -0.3
 0.2







45 FLG filaggrin 2312 0 3.5 2.9
 1.9
 3.2












46 TGM1 transglutaminase 1 7051 0 3.5 3.3
 1.8
 2.8
 -0.1
 1.3


0.8
0.4
 4.0
3.2
 -0.9
 -0.3



47 TMEM45A transmembrane protein 45A 55076 0 3.4 3.0
 1.2
 3.1
 0.1
 1.3
 0.4
 -0.3
 0.6
 0.2
 0.1





48 RGS4 regulator of G protein signaling 4 5999 0 3.4 3.0
 2.1
 3.0
 0.1
 -0.1
 1.0
 0.3
 -0.1







49 CLCA2 chloride channel accessory 2 9635 0 3.4 3.4
 0.9
 2.6
 0.3
-0.8
 0.9
 0.2







50 ITGBL1 integrin subunit beta like 1 9358 0


0.5
 0.6
 0.9
 0.1
 -0.7
 -0.0
 -0.7





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