Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4   ARHGEF3   Rho guanine nucleotide exchange factor 3 
 hsa-r.6   ARHGEF3   Rho guanine nucleotide exchange factor 3 
 hsa-m.7   ARHGEF3   Rho guanine nucleotide exchange factor 3 
 hsa-m2.4   ARHGEF3   Rho guanine nucleotide exchange factor 3 
 hsa-u.4   NET1   neuroepithelial cell transforming 1 
 mcc-u.3   ARHGEF3   Rho guanine nucleotide exchange factor 3 
 mcc-u.3   NET1   neuroepithelial cell transforming 1 
 mmu-u.4   Net1   neuroepithelial cell transforming gene 1 
 mmu-u.4   Arhgef3   Rho guanine nucleotide exchange factor (GEF) 3 
 rno-u.3   Arhgef3   Rho guanine nucleotide exchange factor 3 
 rno-u.3   Net1   neuroepithelial cell transforming 1 
 cfa-u.3   NET1   neuroepithelial cell transforming 1 
 cfa-u.3   ARHGEF3   Rho guanine nucleotide exchange factor 3 
 gga-u.3   ARHGEF3   Rho guanine nucleotide exchange factor 3 
 gga-u.3   NET1   neuroepithelial cell transforming 1 
 dre-u.3   arhgef3   Rho guanine nucleotide exchange factor (GEF) 3 
 dre-u.3   arhgef3l   Rho guanine nucleotide exchange factor (GEF) 3, like 
 dre-u.3   net1   neuroepithelial cell transforming 1 
 sce-u.3   ROM1   Rho family guanine nucleotide exchange factor ROM1 
 sce-u.3   ROM2   Rho family guanine nucleotide exchange factor ROM2 

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Top 50 coexpressed genes to ARHGEF3 (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa4144   Endocytosis  5 231 3.20
 hsa4070   Phosphatidylinositol signaling system  4 90 3.82
 hsa5131   Shigellosis  4 220 2.37
 hsa562   Inositol phosphate metabolism  3 68 2.95
 hsa5200   Pathways in cancer  4 531 -

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hsa:ARHGEF3 (Rho guanine nucleotide exchange factor 3) External Links;


Show/Hide Columns:          
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-u.4
for
ARHGEF3
hsa-r.6
for
ARHGEF3
hsa-m.7
for
ARHGEF3
hsa-m2.4
for
ARHGEF3
hsa-u.4
for
NET1
mcc-u.3
for
ARHGEF3
mcc-u.3
for
NET1
mmu-u.4
for
Net1
mmu-u.4
for
Arhgef3
rno-u.3
for
Arhgef3
rno-u.3
for
Net1
cfa-u.3
for
NET1
cfa-u.3
for
ARHGEF3
gga-u.3
for
ARHGEF3
gga-u.3
for
NET1
dre-u.3
for
arhgef3
dre-u.3
for
arhgef3l
dre-u.3
for
net1
sce-u.3
for
ROM1
sce-u.3
for
ROM2
1 PRKCH protein kinase C eta 5583 0 5.3 4.3
 1.6
 5.1
 1.1
0.9
 4.2
3.8
 2.1
0.6
 0.3
0.2
 2.3
2.2
 2.9
2.1
 0.3
-0.1
 1.3
0.6
 3.7
1.8
 1.7
1.0
 2.3
1.0
 0.8
0.5
 1.5
1.1
 3.4
1.1
 0.7
 1.6
2 IL17RD interleukin 17 receptor D 54756 0 4.6 3.3
 2.2
 4.8
 0.5
 1.1
 1.6
 -0.6
 1.4
 -1.0
 0.2
 -0.6
 2.0
 0.4
 -0.2
 -0.1
 -0.6
 1.6

3 CYTH1 cytohesin 1 9267 0 4.3 4.3
 0.7
 3.2
 1.0
0.5
 1.4
0.6
 0.8
0.4
 1.3
-0.3
 3.0
1.9
 2.8
1.8
 0.2
-0.6
 0.7
-0.7
 1.6
1.3
 1.5
0.7
 1.3
-0.3
 1.3
0.9
 3.6
3.4
 0.9
0.6
 1.1
0.4
 3.9
0.4
4 INPP4A inositol polyphosphate-4-phosphatase type I A 3631 0 4.0 4.2
 1.7
 2.9
 1.8
-1.2
 3.6
0.9
 0.2
-0.9
 -1.0
-1.0
 0.7
0.6
 1.1
0.1
 0.8
-1.0
 1.4
-0.1
 1.6
0.9
 2.1
-0.3
 -0.2
-0.2
 2.8
1.3
 1.1
1.0
 -0.1
-0.5

5 ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 8869 0 3.9 2.9
 2.1
 4.0
 -0.5
 2.7
 0.7
 0.3
 0.8
 2.0
 -0.0
 -0.7
 2.1
 -0.2
 -2.0
 -1.8
 1.4
 -1.3

6 TGFBR2 transforming growth factor beta receptor 2 7048 0 3.9 3.0
 1.3
 3.8
 1.7
 0.3
 0.1
 0.0
 1.9
 0.0
 0.4
 0.2
 1.9
 1.3
 0.3
 1.4
 -0.0
 1.2

7 APOBEC3C apolipoprotein B mRNA editing enzyme catalytic subunit 3C 27350 0 3.8 3.2
 1.8
 3.6
 0.9
0.1
 2.0
1.5
 -0.1
-0.2
 0.3
 0.4
 0.1
 -0.0








8 EXOC2 exocyst complex component 2 55770 0 3.8 4.4
 1.5
 2.2
 -1.2
 1.6
 -1.2
 -0.7
 1.1
 -0.1
 -0.3
 0.1
 0.6
 1.2
 -0.7
 0.2
 -0.6
 1.4
 0.5
 2.1
9 SH3BP5 SH3 domain binding protein 5 9467 0 3.7 4.2
 2.4
 2.4
 -0.1
 3.7
 -1.4
 -0.1
 4.4
 2.3
 0.8
 0.3
 0.2
 -1.7
 0.5
 0.8
-0.8
 0.2
-0.1
 1.1
0.2

10 FYN FYN proto-oncogene, Src family tyrosine kinase 2534 0 3.7 4.7
 1.4
 1.9
 3.4
1.6
 3.5
1.7
 1.2
0.7
 1.8
0.3
 1.9
1.8
 2.0
0.9
 2.6
-0.1
 1.4
0.5
 0.3
0.3
 2.8
1.7
 1.2
0.6
 1.4
1.1
 4.0
2.3
 2.0
1.5

11 ZNF436 zinc finger protein 436 80818 0 3.7 2.6
 1.2
 4.0
 0.8
 1.9
 0.0
 -0.6
 -0.5
 1.1
 0.7
 0.0
 0.6






12 ITPKB inositol-trisphosphate 3-kinase B 3707 0 3.6 3.2
 1.3
 3.3
 -0.1
 0.7
 -1.0



1.8
 1.1
 0.2
 0.8
 1.6
 0.1
 -0.1

13 TMEM229B transmembrane protein 229B 161145 0 3.6 3.2
 1.2
 3.2
 -1.7
 2.2
 -1.3
 -1.6
 2.4
 1.4
 -0.5
 -0.9
 0.0
 1.1
 0.9
 1.3
 0.1
 -1.3

14 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 3708 0 3.6 3.7
 1.8
 2.7
 1.0
-0.2
 3.9
1.4
 2.2
-1.0
 0.7
0.5
 1.6
1.2
 2.7
2.1
 1.3
0.6
 0.8
0.3
 0.9
0.3
 0.9
0.3
 0.2
0.2
 2.0
-0.2
 1.5
1.3
 0.3
-0.2

15 LRCH1 leucine rich repeats and calponin homology domain containing 1 23143 0 3.6 3.2
 0.6
 3.1
 1.3
-0.9
 3.3
0.1
 0.3
-0.7
 -0.5
-1.3
 3.5
-0.3
 1.2
-0.0
 0.3
-0.1
 1.1
-0.0
 0.9
0.8
 2.2
0.9
 1.1
0.3
 2.3
1.0
 0.3
-0.2
 0.2
-0.5

16 PDP1 pyruvate dehydrogenase phosphatase catalytic subunit 1 54704 0 3.6 3.5
 2.0
 2.9
 0.5
0.5
 1.1
1.1
 1.1
1.0
 1.3
-0.0
 1.1
-0.6
 1.8
0.7
 1.1
-0.2
 2.4
-0.3
 1.2
 2.1
0.8
 0.5
-0.2
 0.7
0.3
 -0.2
-0.6
 -1.4
-1.7
 -0.5
 -0.3
17 APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 26060 0 3.5 2.5
 1.4
 3.6
 0.4
 1.1
 -1.4
 -0.2
 1.4
 1.5
 -0.4
 1.6
 2.1
 1.2
 0.2
 0.5
 -0.7
 0.8

18 CASP10 caspase 10 843 0 3.5 3.4
 1.4
 2.7
 0.5
 2.5
 0.6



0.4
 1.0
 0.2
 -0.2




19 RCAN3 RCAN family member 3 11123 0 3.5 2.6
 1.4
 3.5
 1.0
-1.2
 1.8
0.1
 1.4
1.0
 1.0
0.0
 -0.1
-0.2
 0.9
0.5
 0.8
0.2
 1.4
0.3
 2.5
0.7
 0.5
0.1
 1.9
-0.2
 1.2
1.0
 1.1
0.4
 0.5
0.4

20 SEPTIN6 septin 6 23157 0 3.4 4.2
 1.4
 1.8
 1.7
0.5
 2.9
1.8
 1.3
0.3
 1.5
0.2
 1.0
0.5
 0.7
0.5
 0.1
-0.5
 1.7
1.3
 1.0
0.5
 1.3
0.8
 0.3
0.2
 1.2
1.0
 1.9
0.3
 1.8
1.8

21 OSBPL3 oxysterol binding protein like 3 26031 0 3.4 3.5
 1.7
 2.5
 -0.2
 1.5
 -0.1
 1.6
 1.8
 1.8
 -0.1
 0.4
 2.4
 1.0
 0.6
 1.4
 1.9
 1.3

22 MFSD6 major facilitator superfamily domain containing 6 54842 0 3.4 2.7
 1.4
 3.2
 0.5
 2.6
 0.8
 -0.5
 2.1
 0.6
 -0.4
 0.0
 0.3
 2.4
 -0.6
 2.8
0.6
 0.4
-0.4
 0.8
0.4

23 GNPTAB N-acetylglucosamine-1-phosphate transferase subunits alpha and beta 79158 0 3.4 2.9
 0.9
 3.0
 -1.5
 2.1
 -0.2
 1.9
 1.0
 1.2
 0.4
 -0.2
 1.7
 0.6
 -0.3
 -1.0
 0.8
 -1.4

24 APOBEC3G apolipoprotein B mRNA editing enzyme catalytic subunit 3G 60489 0 3.4 2.7
 2.1
 3.2
 0.9
0.1
 2.0
1.5
 -0.1
-0.2
 0.3
 0.4
 0.1
 -0.0








25 FRMD4B FERM domain containing 4B 23150 0 3.4 3.2
 1.5
 2.7
 1.7
 2.1
-1.1
 2.3
-0.7
 0.3
-0.7
 2.6
-0.3
 -0.2
-1.3
 -0.2
-2.0
 0.3
-0.1
 2.0
-1.1
 0.6
-0.4
 1.8
1.2
 1.9
0.5
 0.9
0.6
 1.9
0.9

26 ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 116984 0 3.3 3.3
 0.9
 2.6
 -1.2
-1.5
 3.2
-0.2
 0.4
-0.3
 -0.3
-0.7
 2.5
2.0
 2.6
0.9
 0.6
-0.2
 0.7
0.6
 3.8
3.5
 3.0
-0.2
 0.1
-0.2
 3.5
3.3
 1.9
1.6
 2.1
1.7

27 GSTK1 glutathione S-transferase kappa 1 373156 0 3.3 2.3
 0.9
 3.5
 -0.1
 1.2
 1.0
 0.1
 0.2
 -0.5
 1.1
 -0.9
 0.3
 0.2
 -1.0
 0.9
-0.5
 0.1
-1.4
 -0.6
-1.4

28 TGFBR3 transforming growth factor beta receptor 3 7049 0 3.3 3.3
 1.2
 2.4
 -0.4
 3.7
 -0.2
 2.3
 0.6
 0.9
 1.6
 -0.5
 1.3
 0.8
 1.0
 0.9
 -0.0
 0.1

29 GIT2 GIT ArfGAP 2 9815 0 3.3 3.5
 1.2
 2.3
 0.3
-1.8
 3.9
0.9
 0.5
-0.4
 0.9
-1.1
 2.1
-0.0
 2.0
1.4
 0.1
-0.3
 0.8
-0.2
 1.1
0.2
 0.1
0.0
 0.0
-0.0
 1.3
0.7
 0.9
0.2
 1.1
-1.3

30 LPIN1 lipin 1 23175 0 3.3 3.6
 1.4
 2.1
 0.9
-0.7
 3.9
1.5
 0.4
-0.2
 0.8
0.8
 2.1
0.6
 1.6
1.2
 1.3
0.8
 1.0
0.3
 0.3
-0.7
 2.3
0.3
 1.2
-1.0
 0.2
0.1
 0.6
0.2
 1.4
0.3
 -0.2
 0.8
31 RASSF5 Ras association domain family member 5 83593 0 3.2 2.7
 1.7
 2.9
 0.4
-0.8
 0.9
0.4
 -0.7
-0.8
 -0.5
-0.7
 2.2
-1.0
 2.5
0.4
 0.4
0.0
 0.3
-1.0
 1.0
0.8
 1.2
0.9
 1.4
0.1
 1.1
 1.1
 0.9

32 CBLB Cbl proto-oncogene B 868 0 3.2 3.6
 1.4
 2.0
 -0.9
-1.3
 3.8
1.2
 0.2
-0.0
 2.1
-1.1
 0.9
-0.1
 1.0
-0.7
 0.6
-0.1
 1.7
-0.4
 0.4
0.3
 1.1
0.9
 1.5
-0.4
 0.4
0.4
 1.5
0.8
 1.7
0.8

33 SUSD1 sushi domain containing 1 64420 0 3.2 3.5
 1.1
 2.1
 -0.3
 3.1
 -0.6
 0.6
 2.0
 0.8
 1.0
 -0.9
 -0.8
 -1.0
 -0.4
 3.2
 1.6
 -0.2

34 PIP4K2C phosphatidylinositol-5-phosphate 4-kinase type 2 gamma 79837 0 3.2 4.0
 0.6
 1.5
 1.2
-0.3
 2.5
1.7
 1.7
-0.3
 2.3
0.2
 1.7
0.1
 3.1
1.7
 1.1
0.3
 1.8
0.5
 0.7
-0.1
 1.9
-0.3
 0.3
0.1
 0.6
0.6
 1.0
0.6
 1.9
0.6
 -0.5
 2.6
35 PRKCQ protein kinase C theta 5588 0 3.2 2.5
 1.2
 3.0
 1.1
0.9
 4.2
3.8
 2.1
0.6
 0.3
0.2
 2.3
2.2
 2.9
2.1
 0.3
-0.1
 1.3
0.6
 3.7
1.8
 1.7
1.0
 2.3
1.0
 0.8
0.5
 1.5
1.1
 3.4
1.1
 0.7
 1.6
36 SLC25A12 solute carrier family 25 member 12 8604 0 3.1 2.2
 1.6
 3.3
 0.4
0.4
 2.4
-1.4
 1.1
-2.1
 1.1
-1.0
 1.5
0.6
 0.4
-0.0
 -0.1
-0.2
 -0.7
-1.0
 0.9
0.1
 0.4
0.3
 -1.2
-1.2
 0.1
-0.9
 -1.0
-1.2
 -0.7
-1.4
 2.0
 0.7
37 STAT4 signal transducer and activator of transcription 4 6775 0 3.1 2.6
 1.3
 3.0
 -1.4
 2.8
 -0.2
 0.7
 1.3
 2.0
 -0.3
 1.1
 1.1
 1.9
 0.2
 1.3
 1.2
 -0.7

38 DCAF5 DDB1 and CUL4 associated factor 5 8816 0 3.1 4.2
 1.0
 1.3
 0.3
 2.7
 -0.9
 0.1
 -0.0
 0.0
 0.5
 1.1
 1.1
 -0.1
 -0.2
 -0.2
 -0.2
 -0.4

39 ARL4C ADP ribosylation factor like GTPase 4C 10123 0 3.1 3.0
 1.9
 2.5
 1.5
0.5
 1.2
-0.3
 1.9
0.2
 3.6
1.6
 1.6
1.6
 2.6
-0.3
 0.8
-0.5
 1.5
1.4
 0.3
0.2
 1.2
0.6
 2.0
0.7
 1.2
0.3
 0.7
0.6
 2.1
2.1

40 GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 63917 0 3.1 3.2
 0.4
 2.3
 -1.1
 0.1
 1.1
 -0.0
 1.7
 2.9
 0.4
 0.0
 -1.4
 -1.6
 -0.8
 0.1
 -1.3
 -1.6

41 SLC9A9 solute carrier family 9 member A9 285195 0 3.1 2.9
 0.9
 2.6
 0.6
-0.2
 2.2
1.5
 0.2
-1.4
 0.8
-1.5
 1.5
1.0
 2.3
-0.2
 0.0
-0.9
 1.4
0.7
 1.1
0.2
 1.5
0.1
 1.2
0.3
 1.2
0.6
 0.4
-0.1
 0.9
-0.2
 -1.0
 -0.1
42 ABLIM1 actin binding LIM protein 1 3983 0 3.1 3.2
 0.9
 2.3
 1.1
-0.1
 1.4
0.5
 -0.1
-0.2
 1.3
0.8
 2.3
1.6
 2.0
0.6
 0.3
-0.5
 -0.1
-0.4
 3.1
1.5
 0.7
0.3
 0.9
0.2
 2.1
1.5
 2.0
-0.2
 -0.0
-0.4

43 CNOT4 CCR4-NOT transcription complex subunit 4 4850 0 3.1 3.7
 0.5
 1.8
 0.1
 1.4
 0.1
 1.1
 0.5
 0.8
 0.3
 0.5
 2.0
 0.5
 0.0
 0.2
-0.6
 0.2
-0.2
 0.4
-0.2
 -0.9
 1.5
44 VGLL4 vestigial like family member 4 9686 0 3.1 3.0
 1.3
 2.5
 0.8
 1.3
 -0.5
 -0.2
 -1.0
 2.8
 2.3
 1.0
 0.0
 2.8
 2.7
 0.9
 0.0
 -0.3

45 OSBPL10 oxysterol binding protein like 10 114884 0 3.1 2.9
 1.2
 2.5
 0.7
 2.2
 0.1



-0.2
 2.0
 -1.1
 1.5
 1.0
 0.9
-0.3
 1.1
-0.0

46 IRF2 interferon regulatory factor 2 3660 0 3.1 2.6
 1.4
 2.9
 -0.0
 2.8
 0.7
 0.4
 3.7
 2.6
 1.1
 0.5
 1.0
 1.7
 0.8
 1.6
 0.7
 1.2

47 ZNF792 zinc finger protein 792 126375 0 3.1 1.9
 1.2
 3.5
 1.5
1.4
 1.2
1.1
 2.1
2.1
 0.4
0.2
 1.0
-1.1
 0.2
0.0
 1.0
0.2
 1.6
0.7
 1.6
1.3






48 EVL Enah/Vasp-like 51466 0 3.1 2.8
 0.9
 2.6
 0.6
-1.5
 2.7
0.3
 0.5
-0.7
 -0.0
-1.2
 1.1
1.0
 1.2
-0.2
 0.6
-1.5
 -0.5
-1.5
 1.7
-0.5
 1.5
-0.8
 2.7
0.1
 1.3
-0.4
 3.4
0.4
 2.0
0.9

49 TNIK TRAF2 and NCK interacting kinase 23043 0 3.1 1.8
 1.3
 3.6
 1.4
0.1
 1.3
-0.5
 1.0
-0.7
 0.9
-0.4
 1.8
1.1
 1.6
0.4
 0.1
-0.5
 1.1
0.6
 1.5
-0.2
 3.0
0.4
 1.0
0.3
 1.0
0.3
 2.0
0.2
 0.6
0.6

50 STN1 STN1 subunit of CST complex 79991 0 3.1 2.2
 1.5
 3.2
 1.7
 1.2
 -1.5
 0.8
 -0.5
 -0.4
 -1.7
 -0.1
 0.1
 0.6
 0.3
 -1.0
 0.0
 -1.0

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