Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4   LETM1   leucine zipper and EF-hand containing transmembrane protein 1 
 hsa-r.6   LETM1   leucine zipper and EF-hand containing transmembrane protein 1 
 hsa-m.7   LETM1   leucine zipper and EF-hand containing transmembrane protein 1 
 hsa-m2.4   LETM1   leucine zipper and EF-hand containing transmembrane protein 1 
 mcc-u.3   LETM1   leucine zipper and EF-hand containing transmembrane protein 1 
 mmu-u.4   Letm1   leucine zipper-EF-hand containing transmembrane protein 1 
 rno-u.3   Letm1   leucine zipper and EF-hand containing transmembrane protein 1 
 cfa-u.3   LETM1   leucine zipper and EF-hand containing transmembrane protein 1 
 gga-u.3   LETM1   leucine zipper and EF-hand containing transmembrane protein 1 
 dre-u.3   letm1   leucine zipper-EF-hand containing transmembrane protein 1 
 dme-u.3   Letm1   Leucine zipper and EF-hand containing transmembrane protein 1 
 cel-u.3   letm-1   LETM1 (Leucine zipper, EF-hand, TransMembrane mitochondrial protein) homolog 
 sce-u.3   YLH47   Ylh47p 
 sce-u.3   MDM38   ribosome-binding protein MDM38 

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Top 50 coexpressed genes to LETM1 (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa3013   Nucleocytoplasmic transport  3 96 2.52
 hsa970   Aminoacyl-tRNA biosynthesis  2 44 2.11
 hsa61   Fatty acid biosynthesis  1 18 -
 hsa4217   Necroptosis  2 159 -
 hsa5022   Pathways of neurodegeneration - multiple diseases  2 476 -

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hsa:LETM1 (leucine zipper and EF-hand containing transmembrane protein 1) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-u.4
for
LETM1
hsa-r.6
for
LETM1
hsa-m.7
for
LETM1
hsa-m2.4
for
LETM1
mcc-u.3
for
LETM1
mmu-u.4
for
Letm1
rno-u.3
for
Letm1
cfa-u.3
for
LETM1
gga-u.3
for
LETM1
dre-u.3
for
letm1
dme-u.3
for
Letm1
cel-u.3
for
letm-1
sce-u.3
for
YLH47
sce-u.3
for
MDM38
1 CLUH clustered mitochondria homolog 23277 0 9.7 8.6
 2.8
 8.5
 6.2
 4.8
 3.6
 4.6
 2.5
 2.4
-0.4
 2.2
 3.8
 2.9
 3.3
2 CTBP1 C-terminal binding protein 1 1487 0 8.7 8.0
 2.8
 7.4
 1.8
0.1
 2.8
-0.5
 0.6
-0.5
 3.1
0.1
 0.0
-0.4
 -0.1
-0.6
 -0.4
 -0.9

3 NOP14 NOP14 nucleolar protein 8602 0 8.3 7.6
 4.1
 7.0
 4.6
 1.3
 0.9
 6.2
 5.7
 0.5
 0.2
 1.1
 -0.1
 1.6
4 GAK cyclin G associated kinase 2580 0 7.7 5.3
 3.5
 8.3
 3.2
0.0
 2.7
-0.1
 3.1
0.9
 4.5
-0.8
 1.2
0.0
 0.8
-0.9
 0.9
 1.8
0.7
 0.1
 0.4
5 POLR1A RNA polymerase I subunit A 25885 0 6.8 7.0
 1.8
 4.9
 7.2
 0.9
 1.2
 4.1
 2.2
 2.8
 1.0
 0.2
 -0.9
 -0.0
6 AP3D1 adaptor related protein complex 3 subunit delta 1 8943 0 6.6 5.8
 1.0
 5.9
 3.0
 2.4
 4.6
 3.2
 3.9
 2.6
 -1.1
 2.0
 -0.3
 3.6
7 URB1 URB1 ribosome biogenesis homolog 9875 0 6.6 5.4
 1.5
 6.2
 2.6
 2.3
 0.8
 1.7
 1.8
 -0.8
 0.7
 -1.7
 -0.9
 -0.6
8 GCN1 GCN1 activator of EIF2AK4 10985 0 6.5 6.1
 2.1
 5.3
 3.9
 3.0
 2.7
 3.5
 2.3
 0.6
 -0.9
 0.3
 -0.2
 -0.5
9 SLC27A4 solute carrier family 27 member 4 10999 0 6.5 6.5
 2.5
 4.8
 4.0
0.2
 3.3
1.2
 1.3
-0.4
 3.1
0.4
 1.0
0.7
 2.7
1.3
 1.3
0.1
 0.4
-1.8
 0.1
 -0.9
10 EIF4G1 eukaryotic translation initiation factor 4 gamma 1 1981 1 6.4 6.0
 1.1
 5.2
 5.4
-0.3
 4.6
 3.6
1.3
 5.9
0.9
 2.6
0.8
 2.2
1.7
 2.8
1.1
 2.9
 1.4
 1.3
11 GRPEL1 GrpE like 1, mitochondrial 80273 0 6.2 5.7
 2.3
 5.1
 0.1
 2.2
0.1
 3.4
-0.6
 6.4
1.9
 1.7
0.9
 1.5
0.8
 1.3
 3.1
 -0.4
 0.5
12 NCLN nicalin 56926 0 6.2 5.5
 2.1
 5.3
 5.2
 3.1
 0.9
 2.8
 2.6
 0.6
-0.6
 0.6
 1.3

13 DNAJC11 DnaJ heat shock protein family (Hsp40) member C11 55735 0 6.0 5.5
 1.7
 5.0
 7.7
 5.3
 2.5
 3.6
 1.9
 0.6
-0.0
 3.7
 4.2

14 BOP1 BOP1 ribosomal biogenesis factor 23246 0 5.9 6.2
 1.6
 4.1
 3.3
 2.8
 2.5
 3.3
 -0.6
 -0.0
 0.6
 0.7
 0.9
 1.0
15 FASN fatty acid synthase 2194 0 5.8 5.1
 1.9
 5.1
 5.0
 2.8
 2.3
 2.9
 -0.7
 1.1
 2.4
0.8
 -0.2

16 FEM1A fem-1 homolog A 55527 0 5.7 6.3
 2.9
 3.8
 1.1
0.8
 4.3
-1.2
 1.9
-1.2
 2.1
0.5
 0.1
-0.2
 -1.4
-1.6
 -0.8
 4.6

17 NOC2L NOC2 like nucleolar associated transcriptional repressor 26155 0 5.7 5.5
 2.3
 4.5
 4.5
 0.7
 0.8
 2.9
 1.3
 0.7
 0.5
 2.4
 0.1
 1.1
18 ATAD3A ATPase family AAA domain containing 3A 55210 0 5.6 5.7
 1.9
 4.2
 2.4
1.0
 3.5
 3.4
 4.2
 0.9
 0.6
 1.0
 5.6

19 VARS1 valyl-tRNA synthetase 1 7407 0 5.6 4.8
 1.1
 5.0
 5.1
4.7
 2.8
0.7
 1.3
1.0
 4.0
1.5
 0.1
-0.5
 0.6
-0.3
 3.7
0.4
 3.5
2.9
 0.4
 1.9
20 ELAC2 elaC ribonuclease Z 2 60528 0 5.5 5.5
 1.9
 4.2
 4.5
 5.0
 5.0
 4.0
 1.3
 0.5
 2.4
 2.7
 0.8
 0.8
21 SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 6597 0 5.5 4.8
 1.6
 4.9
 4.3
0.5
 4.2
1.2
 3.1
0.3
 2.1
-1.5
 1.5
0.1
 1.0
0.8
 0.2
 3.1
1.2
 1.5
-0.2
 0.9
0.7
22 TTLL12 tubulin tyrosine ligase like 12 23170 0 5.5 5.2
 1.5
 4.4
 2.8
 1.5
 0.1
 2.0
 0.8
 -2.1
 -0.1
 1.2

23 AFG3L2 AFG3 like matrix AAA peptidase subunit 2 10939 0 5.4 5.0
 1.8
 4.6
 4.5
4.1
 6.4
5.1
 5.5
4.1
 2.9
1.8
 4.6
-0.0
 2.7
1.0
 5.2
5.0
 3.9
3.3
 2.8
2.6
 2.8
2.7
24 RRP1B ribosomal RNA processing 1B 23076 0 5.4 4.9
 1.4
 4.6
 3.6
2.2
 2.9
0.7
 0.1
-0.0
 3.8
3.3
 4.4
 -0.2
-0.4
 0.9
 0.4
 0.4
 -0.5
25 TNPO2 transportin 2 30000 0 5.4 5.2
 1.6
 4.3
 1.8
1.6
 0.3
-1.1
 1.1
0.3
 2.7
1.3
 1.7
0.7
 2.3
1.5
 0.0
-0.5
 1.0
 -1.9
 1.0
26 NOL6 nucleolar protein 6 65083 0 5.4 5.8
 1.6
 3.7
 4.2
 3.0
 1.5
 3.3
 -0.2
 0.2
 0.4
 -0.8
 0.3
 -0.6
27 UBE3C ubiquitin protein ligase E3C 9690 0 5.3 4.5
 1.6
 4.9
 5.2
 3.4
 3.4
 2.1
 2.5
 -0.2
 2.2
 3.5
 0.7
 -0.9
28 ABCF2 ATP binding cassette subfamily F member 2 10061 0 5.3 5.7
 1.7
 3.6
 4.9
 3.2
 1.8
 3.8
 1.4
 0.5
-0.1
 1.4
 0.4
 1.8
 -0.5
29 PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase 192111 0 5.3 5.1
 2.2
 4.1
 3.2
 1.8
 2.3
 1.4
 1.0
 1.7
 -2.6
 1.4

30 PMPCA peptidase, mitochondrial processing subunit alpha 23203 0 5.3 5.0
 1.2
 4.3
 5.7
 3.5
 3.3
 4.2
 2.5
 0.4
 1.8
 2.4
 2.6
 3.6
31 LARP1 La ribonucleoprotein 1, translational regulator 23367 0 5.2 4.5
 0.9
 4.6
 2.6
0.7
 1.0
 1.6
1.2
 3.2
-0.1
 1.3
1.2
 2.0
1.3
 2.1
 1.3
 2.5
0.7
 2.2
0.6
32 MYBBP1A MYB binding protein 1a 10514 0 5.2 4.8
 2.7
 4.4
 3.8
 0.7
 0.9
 4.1
 3.3
 2.7
 0.2
-0.4
 -0.7
33 TADA2B transcriptional adaptor 2B 93624 0 5.2 4.3
 2.9
 4.9
 0.8
0.8
 3.3
-1.0
 1.9
-1.8
 3.5
-0.0
 2.1
-1.7
 0.3
0.0
 0.0
-2.7
 4.0
 -0.4
 1.8
34 KPNA6 karyopherin subunit alpha 6 23633 0 5.2 5.6
 1.7
 3.5
 2.0
1.5
 2.8
1.1
 2.6
2.5
 2.0
1.6
 3.6
2.3
 1.6
1.5
 -0.2
 -0.0
 -0.7
 1.1
35 VPS4A vacuolar protein sorting 4 homolog A 27183 0 5.2 5.2
 2.2
 4.0
 2.2
-0.9
 3.1
0.1
 2.9
0.1
 1.0
0.1
 0.8
-0.4
 2.7
0.7
 0.7
 0.2
 1.7
 2.0
36 TMEM129 transmembrane protein 129, E3 ubiquitin ligase 92305 0 5.2 4.6
 2.7
 4.5
 0.3
 1.8
 0.5
 3.4
 1.0
 0.2
 -1.2
 0.1

37 POLG DNA polymerase gamma, catalytic subunit 5428 0 5.2 4.6
 1.7
 4.5
 3.7
 0.6
 1.4
 5.7
 -0.7
 0.6
 0.6
 -0.4
 -0.4
 -0.1
38 TUFM Tu translation elongation factor, mitochondrial 7284 0 5.2 5.4
 1.8
 3.7
 4.2
 5.9
 4.2
 3.7
1.3
 1.7
0.2
 3.4
3.4
 0.1
 1.2
39 IRGQ immunity related GTPase Q 126298 0 5.2 5.1
 1.2
 4.0
 3.0
 1.2
 2.5
 -0.2





40 KIF1C kinesin family member 1C 10749 0 5.1 4.0
 1.4
 5.0
 2.6
0.4
 2.1
1.5
 1.8
-1.1
 1.7
1.4
 2.4
-0.6
 0.7
0.5
 2.1
 0.5

41 URB2 URB2 ribosome biogenesis homolog 9816 0 5.1 5.2
 2.3
 3.8
 3.0
 -0.2
 1.3
 1.5
 1.3
 0.8



42 TOMM40 translocase of outer mitochondrial membrane 40 10452 0 5.1 4.1
 1.7
 4.9
 5.4
0.9
 4.8
2.3
 5.5
2.3
 5.1
0.7
 1.1
0.5
 0.9
-0.2
 -0.9
-0.9
 1.5
 1.3
 1.7
43 UPF1 UPF1 RNA helicase and ATPase 5976 0 5.1 3.7
 1.1
 5.3
 3.6
 2.2
 1.1
 2.6
 3.0
 2.8
 2.2
 2.0
 -0.2
 -0.4
44 MARS2 methionyl-tRNA synthetase 2, mitochondrial 92935 0 5.1 4.3
 1.2
 4.6
 1.5
 1.4
 3.5
 0.6
 1.3
 -1.6
 -0.4
 1.0
 1.8
 1.8
45 TBRG4 transforming growth factor beta regulator 4 9238 0 5.0 4.8
 0.5
 4.0
 4.0
 4.2
 2.4
 4.6
 1.2
 0.6
 0.9


46 KLHL18 kelch like family member 18 23276 0 5.0 4.8
 1.3
 3.9
 1.6
 1.5
 2.7
 1.8
 -1.1
 1.2
 -0.8
 1.5

47 HTT huntingtin 3064 0 5.0 4.5
 2.9
 4.2
 2.5
 1.1
 2.2
 2.3
 1.9
 1.6
 2.3


48 GRWD1 glutamate rich WD repeat containing 1 83743 0 4.9 4.9
 2.4
 3.8
 4.3
 0.6
 0.3
 2.3
2.0
 -0.8
 -0.2
 0.8
 -0.4
49 PDCD11 programmed cell death 11 22984 0 4.9 4.7
 2.6
 4.0
 2.9
 0.8
 1.0
 1.4
 3.7
 0.6
 0.3
 3.0
 -0.8
 0.4
50 GTF3C1 general transcription factor IIIC subunit 1 2975 0 4.9 4.4
 1.0
 4.3
 3.7
 3.3
 -0.3
 1.2
 1.2
 -1.8
-2.6
 -0.2
 -0.4

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