Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4   PIKFYVE   phosphoinositide kinase, FYVE-type zinc finger containing 
 hsa-r.6   PIKFYVE   phosphoinositide kinase, FYVE-type zinc finger containing 
 hsa-m.7   PIKFYVE   phosphoinositide kinase, FYVE-type zinc finger containing 
 hsa-m2.4   PIKFYVE   phosphoinositide kinase, FYVE-type zinc finger containing 
 mcc-u.3   PIKFYVE   phosphoinositide kinase, FYVE-type zinc finger containing 
 mmu-u.4   Pikfyve   phosphoinositide kinase, FYVE type zinc finger containing 
 rno-u.3   Pikfyve   phosphoinositide kinase, FYVE-type zinc finger containing 
 cfa-u.3   PIKFYVE   phosphoinositide kinase, FYVE-type zinc finger containing 
 gga-u.3   PIKFYVE   phosphoinositide kinase, FYVE-type zinc finger containing 
 dre-u.3   pikfyve   phosphoinositide kinase, FYVE finger containing 
 sce-u.3   FAB1   1-phosphatidylinositol-3-phosphate 5-kinase 
 spo-u.3   mug71   putative endoribonuclease 

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Top 50 coexpressed genes to PIKFYVE (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa4120   Ubiquitin mediated proteolysis  3 134 2.12
 hsa562   Inositol phosphate metabolism  1 73 -
 hsa1521   EGFR tyrosine kinase inhibitor resistance  1 79 -
 hsa4144   Endocytosis  2 251 -
 hsa5014   Amyotrophic lateral sclerosis  2 364 -

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hsa:PIKFYVE (phosphoinositide kinase, FYVE-type zinc finger containing) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-u.4
for
PIKFYVE
hsa-r.6
for
PIKFYVE
hsa-m.7
for
PIKFYVE
hsa-m2.4
for
PIKFYVE
mcc-u.3
for
PIKFYVE
mmu-u.4
for
Pikfyve
rno-u.3
for
Pikfyve
cfa-u.3
for
PIKFYVE
gga-u.3
for
PIKFYVE
dre-u.3
for
pikfyve
sce-u.3
for
FAB1
spo-u.3
for
mug71
1 BIRC6 baculoviral IAP repeat containing 6 57448 0 10.5 11.7
 3.1
 6.8
 4.4
 7.5
 5.6
 4.4
 4.9
 0.7

2 TRIP12 thyroid hormone receptor interactor 12 9320 0 8.6 8.9
 2.1
 6.3
 1.7
 5.0
 2.8
 2.2
 4.5
 0.5
 2.9
 -0.5
3 KIAA1109 KIAA1109 84162 0 8.1 9.6
 2.7
 4.7
 3.1
 6.8
 2.7
 1.8
 3.7
 2.7
 5.5
4 TNKS2 tankyrase 2 80351 0 8.1 9.5
 1.8
 4.9
 4.8
1.9
 5.1
4.9
 1.6
0.7
 1.5
0.7
 2.7
1.7
 1.4
0.6

5 FRYL FRY like transcription coactivator 285527 0 8.1 9.7
 1.5
 4.5
 2.6
0.4
 3.6
1.1
 1.8
1.4
 2.5
1.9
 2.0
1.7
 3.1
0.7
 6.0
 0.7
0.1
6 RANBP2 RAN binding protein 2 5903 0 8.1 10.7
 1.8
 3.4
 2.6
 4.9
 2.2
 1.0
1.6

7 INO80D INO80 complex subunit D 54891 0 7.9 8.9
 2.3
 4.9
 2.5
 5.8
 2.0
 1.6
 3.2
 1.2

8 USP24 ubiquitin specific peptidase 24 23358 0 7.8 9.9
 2.2
 3.9
 5.1
1.3
 6.0
4.7
 2.6
1.4
 2.4
1.9
 2.6
2.3
 2.4
2.2

9 BRWD3 bromodomain and WD repeat domain containing 3 254065 0 7.6 9.6
 1.4
 3.7
 2.8
2.4
 5.5
3.9
 3.7
1.0
 5.3
2.4
 3.5
2.7
 0.8
-0.4

10 FAM126B family with sequence similarity 126 member B 285172 0 7.1 8.3
 2.1
 4.2
 3.4
1.7
 6.5
2.0
 2.3
-1.0
 2.9
2.2
 1.6
0.3
 1.2
0.2

11 MED13 mediator complex subunit 13 9969 0 7.0 7.9
 1.4
 4.4
 4.5
1.0
 3.6
1.3
 3.5
0.7
 3.5
3.0
 3.8
3.2
 2.4
2.1

12 ZBED6 zinc finger BED-type containing 6 100381270 0 7.0 7.1
 0.9
6.6
 5.9
 2.0
 6.0



13 SHPRH SNF2 histone linker PHD RING helicase 257218 0 7.0 8.1
 1.5
 4.2
 3.5
 8.2
 0.3
 2.7
 2.6
 0.7
 1.8
 0.6
14 USP34 ubiquitin specific peptidase 34 9736 0 6.9 6.2
 2.0
 5.9
 6.8
 4.6
 1.8
 3.8
 4.5
 1.7

15 HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 8925 0 6.8 8.2
 1.5
 3.7
 2.9
 5.2
 1.9
 2.6
 3.1
 2.5

16 PCNX1 pecanex 1 22990 0 6.8 6.2
 1.4
 5.6
 3.9
1.2
 1.0
-0.1
 0.9
-0.0
 1.3
1.1
 2.7
1.1
 2.2
0.3
-0.6
17 ATAD2B ATPase family AAA domain containing 2B 54454 0 6.7 7.8
 2.9
 4.0
 4.4
0.5
 2.4
1.7
 0.7
 1.0
0.6
 3.1
0.6
 0.2
 3.4
18 PAN3 poly(A) specific ribonuclease subunit PAN3 255967 0 6.6 8.3
 1.9
 3.3
 2.8
 2.6
 1.9
 2.8
 2.8
 2.1
 1.0
 -0.9
19 PUM2 pumilio RNA binding family member 2 23369 0 6.6 7.6
 2.1
 4.1
 0.8
0.8
 4.8
0.5
 1.6
0.2
 0.8
0.3
 1.0
0.2
 -0.6
-1.4
 2.4
1.4
 -0.4
20 KAT6A lysine acetyltransferase 6A 7994 0 6.6 7.6
 1.1
 4.0
 1.6
 1.9
 1.8
 2.3
 3.3
 1.9

21 NF1 neurofibromin 1 4763 0 6.5 7.6
 1.6
 3.8
 3.3
 5.0
 1.7
 2.1
 2.7
 0.7
0.4
 3.9
3.7
22 PTAR1 protein prenyltransferase alpha subunit repeat containing 1 375743 0 6.5 8.5
 1.4
 2.8
 4.6
 4.2
 0.1
 0.1
 1.3
 -0.4

23 VPS13C vacuolar protein sorting 13 homolog C 54832 0 6.4 7.7
 2.3
 3.5
 2.1
1.1
 6.2
5.0
 3.1
 4.2
1.6
 2.6
1.4
 2.3
1.9
 4.9
 1.8
24 SETX senataxin 23064 0 6.4 5.5
 2.3
 5.7
 5.1
 3.0
 3.5
 3.8
 1.6
 1.7
 2.8
 0.8
25 FNIP1 folliculin interacting protein 1 96459 0 6.3 7.5
 1.6
 3.6
 2.6
1.6
 3.1
2.5
 4.6
2.0
 3.6
0.9
 1.4
1.0
 3.3
1.9

26 ANKRD17 ankyrin repeat domain 17 26057 0 6.3 7.3
 0.9
 3.8
 4.3
2.8
 4.3
3.7
 2.0
1.8
 2.8
2.1
 2.6
2.0
 0.9

27 KIDINS220 kinase D interacting substrate 220 57498 0 6.3 6.9
 1.2
 4.1
 6.3
 4.3
 -0.2
 3.5
 3.3
 3.6
0.2

28 VPS13B vacuolar protein sorting 13 homolog B 157680 0 6.2 7.2
 1.5
 3.7
 7.4
 5.6
 0.0
 2.8
 3.6
 -0.2

29 CHD6 chromodomain helicase DNA binding protein 6 84181 0 6.2 7.5
 1.3
 3.4
 5.3
2.1
 3.5
3.4
 0.6
0.5
 2.7
2.0
 3.4
3.0
 2.3
1.8

30 CLASP1 cytoplasmic linker associated protein 1 23332 0 6.2 7.4
 1.8
 3.5
 2.8
2.6
 3.9
2.0
 1.0
-1.2
 0.9
-0.0
 3.0
1.4
 5.5
4.1
0.5
31 ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 23527 0 6.2 5.9
 1.7
 5.0
 3.3
0.5
 2.8
0.1
 1.8
0.4
 3.4
-0.5
 1.0
0.6
 2.0
1.7
 -1.4
 0.9
-0.1
32 HELZ helicase with zinc finger 9931 0 6.1 7.5
 1.1
 3.2
 2.7
 2.2
 -0.0
 1.8
 2.9
 1.4

33 RAPGEF6 Rap guanine nucleotide exchange factor 6 51735 0 6.0 7.1
 1.7
 3.5
 5.7
3.1
 5.5
1.2
 2.0
1.8
 5.7
4.0
 3.6
2.5
 2.9
2.1
0.7
34 TNKS tankyrase 8658 0 6.0 6.8
 1.4
 3.7
 4.8
1.9
 5.1
4.9
 1.6
0.7
 1.5
0.7
 2.7
1.7
 1.4
0.6

35 RC3H2 ring finger and CCCH-type domains 2 54542 0 6.0 8.1
 1.0
 2.4
 4.7
0.8
 2.9
2.6
 3.8
0.4
 3.4
0.3
 2.9
2.5
 0.0
-0.9

36 LTN1 listerin E3 ubiquitin protein ligase 1 26046 0 6.0 7.8
 1.2
 2.7
 3.1
 6.0
 0.7
 2.2
 3.0
 0.3
 1.3
 1.3
37 SF3B1 splicing factor 3b subunit 1 23451 0 6.0 6.2
 2.4
 4.3
 4.8
 3.3
 1.3
 2.9
 2.1
-0.9
 1.7
38 PBRM1 polybromo 1 55193 0 5.9 7.1
 0.5
 3.3
 3.7
 0.8
 -0.2
 2.6
 1.4
 3.3
2.1
 1.7
-0.1
39 GAPVD1 GTPase activating protein and VPS9 domains 1 26130 0 5.9 5.9
 1.4
 4.4
 3.6
 4.4
 -0.3
 1.7
 1.3
 2.0

40 UBN2 ubinuclein 2 254048 0 5.9 7.2
 1.0
 3.1
 2.7
0.5
 2.0
0.5
 2.3
-0.1
 2.9
-0.8
 1.5
1.3
 1.2
0.9
0.0
41 DMXL2 Dmx like 2 23312 0 5.9 6.9
 1.1
 3.4
 4.8
0.9
 4.6
3.1
 5.4
2.0
 5.3
0.7
 3.1
1.1
 4.3
1.2
 4.0
42 PIK3C2A phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha 5286 0 5.7 6.1
 1.7
 4.0
 6.4
0.9
 4.3
-0.4
 1.7
-1.4
 1.4
1.1
 4.0
1.1
 2.1
1.1

43 MKLN1 muskelin 1 4289 0 5.7 4.9
 1.7
 5.2
 3.8
 2.0
 -0.3
 0.2
 1.0
 1.4

44 ZYG11B zyg-11 family member B, cell cycle regulator 79699 0 5.7 8.5
 0.7
 1.5
 3.7
0.1
 3.2
1.0
 4.2
 0.5
 1.5
 0.1
-0.0

45 IREB2 iron responsive element binding protein 2 3658 0 5.7 7.8
 1.5
 2.3
 2.6
-1.2
 4.7
1.2
 0.2
-0.6
 2.3
0.7
 2.2
-0.1
 0.9
0.2
0.6
46 PHF3 PHD finger protein 3 23469 0 5.7 6.6
 1.4
 3.4
 2.5
 2.6
 2.5
 1.1
 0.7
 1.3

47 NBEAL1 neurobeachin like 1 65065 0 5.7 6.9
 0.5
 3.0
 4.5
0.9
 7.5
-0.6
 3.5
0.9
 3.5
0.6
 1.5
1.2
 0.5
0.4

48 DCAF17 DDB1 and CUL4 associated factor 17 80067 0 5.6 5.9
 1.6
 3.9
 3.0
 2.4
 2.6
 1.8
 -1.4
 1.0

49 TTBK2 tau tubulin kinase 2 146057 0 5.6 7.0
 1.5
 2.8
 1.1
 2.8
 1.3
 1.4
 0.2
 1.8
0.2

50 ARFGEF2 ADP ribosylation factor guanine nucleotide exchange factor 2 10564 0 5.6 5.4
 2.3
 4.4
 3.0
2.9
 4.2
3.1
 3.4
1.3
 4.4
2.6
 3.3
2.9
 1.7
1.5
 3.4
 1.7
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