Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4   CLDN16   claudin 16 
 hsa-r.6   CLDN16   claudin 16 
 hsa-m.7   CLDN16   claudin 16 
 hsa-m2.4   CLDN16   claudin 16 
 rno-u.3   Cldn16   claudin 16 
 cfa-u.3   CLDN16   claudin 16 
 gga-u.3   CLDN16   claudin 16 

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Top 50 coexpressed genes to CLDN16 (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa140   Steroid hormone biosynthesis  3 45 3.48
 hsa830   Retinol metabolism  3 52 3.29
 hsa982   Drug metabolism - cytochrome P450  3 56 3.20
 hsa980   Metabolism of xenobiotics by cytochrome P450  3 61 3.09
 hsa4514   Cell adhesion molecules  3 130 2.16

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hsa:CLDN16 (claudin 16) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-u.4
for
CLDN16
hsa-r.6
for
CLDN16
hsa-m.7
for
CLDN16
hsa-m2.4
for
CLDN16
rno-u.3
for
Cldn16
cfa-u.3
for
CLDN16
gga-u.3
for
CLDN16
1 CLDN1 claudin 1 9076 11 15.1 17.8
 1.6
 8.8
 0.2
-0.3
 2.1
0.4
 3.3
2 MUC15 mucin 15, cell surface associated 143662 0 5.3 5.6
 0.8
 3.7
0.0
3 BBOX1 gamma-butyrobetaine hydroxylase 1 8424 0 4.8 4.7
 0.7
 3.6
 -1.4
 0.5
 -0.4
4 ADGRF1 adhesion G protein-coupled receptor F1 266977 0 4.2 3.5
 0.2
 3.9
 2.5
 2.7
5 P3H2 prolyl 3-hydroxylase 2 55214 0 4.0 4.4
 -0.3
 2.6
 1.2
 0.0
 0.6
6 KCNJ16 potassium inwardly rectifying channel subfamily J member 16 3773 0 3.9 3.9
 1.0
 2.9
 1.5
 1.9
 1.5
7 CLDN8 claudin 8 9073 0 3.8 4.3
 0.4
 2.4
 1.3
 0.8
8 DCDC2 doublecortin domain containing 2 51473 0 3.7 2.4
 1.8
 4.1
 2.2
 1.8
 0.8
0.1
9 SRD5A2 steroid 5 alpha-reductase 2 6716 0 3.7 3.2
 -1.5
 3.3
 -0.9
 0.2
 1.1
0.2
10 DNAH5 dynein axonemal heavy chain 5 1767 0 3.6 3.0
 0.8
 3.2
 1.1
0.9
 0.9
0.8
 1.7
1.7
11 AGXT2 alanine--glyoxylate aminotransferase 2 64902 0 3.5 2.5
 1.9
 3.7
 1.5
0.9
 0.6
0.4
 0.5
0.4
12 HAO2 hydroxyacid oxidase 2 51179 0 3.4 2.5
 1.8
 3.4
 2.7
1.2
 0.6
 1.9
0.3
13 DSG1 desmoglein 1 1828 0 3.4 3.5
 0.5
 2.4
 0.3
0.2
 1.3
1.1
 1.0
0.5
14 UGT2A1 UDP glucuronosyltransferase family 2 member A1 complex locus 10941 0 3.3 3.2
2.7
 0.9
0.9
 1.1
0.7
 2.3
0.8
15 SLC16A12 solute carrier family 16 member 12 387700 0 3.3 2.1
3.8
 1.3
1.1
 1.3
0.7
 1.8
1.6
16 ANO3 anoctamin 3 63982 0 3.3 3.4
 0.5
 2.4
 1.2
0.9
 -0.2
-0.9
 -0.2
-0.3
17 ACE2 angiotensin converting enzyme 2 59272 0 3.3 2.1
 0.5
 3.7
 1.1
-0.3
 0.4
-0.5
 0.8
-0.8
18 SERPINA6 serpin family A member 6 866 0 3.3 2.7
 1.2
 3.0
 -0.5

19 MMP7 matrix metallopeptidase 7 4316 0 3.2 2.8
 0.5
 2.9
 1.1
0.9
 0.5
-0.2
 0.6
0.0
20 SLC2A2 solute carrier family 2 member 2 6514 0 3.2 2.2
 0.4
 3.4
 1.6
0.6
 0.8
0.5
 2.9
1.6
21 TMPRSS3 transmembrane serine protease 3 64699 0 3.2 1.9
 0.6
 3.7
0.6
22 UGT1A1 UDP glucuronosyltransferase family 1 member A1 54658 0 3.1 1.9
3.7
 0.9
0.9
 1.1
0.7
 2.3
0.8
23 CYP4B1 cytochrome P450 family 4 subfamily B member 1 1580 0 3.1 2.4
 0.8
 3.1
 3.3
2.9
 4.8
4.1
 1.5
-0.2
24 ABCA13 ATP binding cassette subfamily A member 13 154664 0 3.1 1.9
 -0.3
 3.6
 0.9
 1.3
 1.3
25 NWD1 NACHT and WD repeat domain containing 1 284434 0 3.1 2.7
2.7
 -1.4
 1.1
26 AADACL2 arylacetamide deacetylase like 2 344752 0 3.1 2.9
 0.8
 2.5
 1.0
-0.1
 0.1
-0.0
 1.0
0.9
27 UNC13C unc-13 homolog C 440279 0 3.1 2.8
 0.2
 2.6
 1.3
0.6
 1.1
-0.6
 0.7
0.1
28 ADGRF4 adhesion G protein-coupled receptor F4 221393 0 3.1 2.9
 0.7
 2.5

-0.1
29 IL1RAP interleukin 1 receptor accessory protein 3556 0 3.0 3.5
 -0.1
 1.8
 -1.0
 0.5
 0.3
30 TP63 tumor protein p63 8626 0 3.0 3.3
 0.4
 2.1
1.1
 0.5
31 CFAP43 cilia and flagella associated protein 43 80217 0 3.0 2.1
 0.6
 3.2
 0.4
-0.2
32 CX3CL1 C-X3-C motif chemokine ligand 1 6376 0 3.0 2.2
 -0.1
 3.1
 0.4
 0.6
33 SCEL sciellin 8796 0 3.0 3.6
 0.3
 1.6
 0.3
 1.4
 1.0
34 C6 complement C6 729 0 3.0 2.8
 0.4
 2.4
 -0.4
 0.1
 0.6
35 CFAP57 cilia and flagella associated protein 57 149465 0 2.9 3.2
 -0.5
 1.9
 0.5
2.3
36 MYO3B myosin IIIB 140469 0 2.9 2.7
 1.2
 2.4
 2.6
 0.6
37 GJB4 gap junction protein beta 4 127534 0 2.9 3.6
 1.0
 1.5
1.0
38 CWH43 cell wall biogenesis 43 C-terminal homolog 80157 0 2.9 3.5
 -0.7
 1.5
 3.1
1.3
39 SLC26A7 solute carrier family 26 member 7 115111 0 2.9 1.6
 0.1
 3.5
 2.3
 1.3
40 ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 131 0 2.9 3.4
 0.9
 1.7
 1.7
0.3
 0.7
0.1
 1.2
0.7
41 HRG histidine rich glycoprotein 3273 0 2.9 3.0
 1.2
 2.1
 0.2
0.1
 0.9
 0.8
42 ROS1 ROS proto-oncogene 1, receptor tyrosine kinase 6098 0 2.9 2.0
 0.4
 3.0
 1.1
0.8
43 VTCN1 V-set domain containing T cell activation inhibitor 1 79679 0 2.9 2.4
 1.3
 2.6
 -0.9
 0.8
44 EHF ETS homologous factor 26298 0 2.9 2.2
 0.4
 2.8
 2.1
1.3
 1.6
0.4
 1.4
1.2
45 RASSF9 Ras association domain family member 9 9182 0 2.9 3.1
 0.5
 2.0
 1.5
0.4
 0.6
-1.1
 0.6
0.5
46 AFM afamin 173 0 2.9 2.5
 1.4
 2.6
 1.8
 0.7
47 CYP4A11 cytochrome P450 family 4 subfamily A member 11 1579 0 2.9 2.8
 3.0
 2.2
 3.3
2.9
 4.8
4.1
 1.5
-0.2
48 AADAC arylacetamide deacetylase 13 0 2.9 3.4
 0.4
 1.7
 1.0
-0.1
 0.1
-0.0
 1.0
0.9
49 CFAP47 cilia and flagella associated protein 47 286464 0 2.9 3.1
 5.4
 1.9
 -0.3
0.6
50 DEFB1 defensin beta 1 1672 0 2.8 1.3
 0.9
 3.7
 1.9
 1.1
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