Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4   IRX5   iroquois homeobox 5 
 hsa-r.6   IRX5   iroquois homeobox 5 
 hsa-m.7   IRX5   iroquois homeobox 5 
 hsa-m2.4   IRX5   iroquois homeobox 5 
 mcc-u.3   IRX5   iroquois homeobox 5 
 mmu-u.4   Irx5   Iroquois homeobox 5 
 rno-u.3   Irx5   iroquois homeobox 5 
 cfa-u.3   IRX5   iroquois homeobox 5 
 gga-u.3   IRX5   iroquois homeobox 5 
 dre-u.3   irx5a   iroquois homeobox 5a 

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Top 50 coexpressed genes to IRX5 (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa4950   Maturity onset diabetes of the young  2 20 2.79
 hsa3018   RNA degradation  1 79 -
 hsa4350   TGF-beta signaling pathway  2 94 -
 hsa4550   Signaling pathways regulating pluripotency of stem cells  2 143 -
 hsa4060   Cytokine-cytokine receptor interaction  2 295 -

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hsa:IRX5 (iroquois homeobox 5) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-u.4
for
IRX5
hsa-r.6
for
IRX5
hsa-m.7
for
IRX5
hsa-m2.4
for
IRX5
mcc-u.3
for
IRX5
mmu-u.4
for
Irx5
rno-u.3
for
Irx5
cfa-u.3
for
IRX5
gga-u.3
for
IRX5
dre-u.3
for
irx5a
1 IRX3 iroquois homeobox 3 79191 49 21.5 23.5
 11.2
 14.3
 8.8
 25.7
 18.5
 17.1
 11.7
 12.8
3.7
2 CRNDE colorectal neoplasia differentially expressed 643911 18 21.2 21.4
 10.9






3 IRX1 iroquois homeobox 1 79192 0 7.2 7.2
 2.4
 5.5
 7.5
 12.1
 6.9
 3.5
 3.8
 11.3
4 IRX2 iroquois homeobox 2 153572 6 7.1 7.2
 2.7
 5.3
 8.1
 17.5
 10.9
 4.3
 3.7
 7.9
5.3
5 IRX6 iroquois homeobox 6 79190 6 6.9 7.7
4.4
5.2
 4.5
 0.5
 5.6
2.3
 4.7
4.3
6 C5orf38 chromosome 5 open reading frame 38 153571 0 6.0 6.2
4.4





7 LRRC26 leucine rich repeat containing 26 389816 0 5.3 1.6
7.8
0.4
1.6
 1.6
8 FOXC1 forkhead box C1 2296 0 5.3 4.3
 2.1
 4.9
 2.6
0.4
 6.3
4.4
 1.8
1.6
 2.0
1.6
 1.9
1.4
 4.5
3.9
9 TFAP2A transcription factor AP-2 alpha 7020 0 5.0 5.8
 2.8
 3.1
 2.8
1.8
 5.5
5.1
 3.1
2.5
 2.3
2.0
 1.3
1.2
 3.8
3.6
10 GBX2 gastrulation brain homeobox 2 2637 0 4.6 2.7
 0.8
 5.4
2.3

0.7
 4.1
2.7
11 SIX2 SIX homeobox 2 10736 0 4.6 4.0
 1.0
 4.1
 2.1
1.9
 4.6
 1.5
 2.2
0.8
 2.5
1.7
 2.8
1.3
12 FOXA1 forkhead box A1 3169 0 4.5 4.5
 1.9
 3.4
 1.2
 3.8
 2.3
 0.8
 1.0
 5.5
13 FOXC2 forkhead box C2 2303 0 4.4 1.8
 0.9
 5.9
3.4
 1.0
 0.9
 1.1
 1.9
14 OTX1 orthodenticle homeobox 1 5013 0 4.3 3.0
 0.9
 4.6
 2.9
0.6
 2.8
2.5
 0.6
-0.1
3.3
0.1
 3.9
2.8
15 INHBB inhibin subunit beta B 3625 0 4.3 2.2
 1.7
 5.4
 0.9
0.2
 1.5
-0.8
 0.8
-0.1
 0.5
-0.2
 0.2
-0.5
 2.7
1.6
16 POU3F3 POU class 3 homeobox 3 5455 0 4.3 3.3
 1.3
 4.2
 0.6
0.2
 2.3
1.4
 1.2
0.6
 0.7
-0.1
 2.5
0.9
 4.8
4.3
17 POU3F2 POU class 3 homeobox 2 5454 0 4.1 3.4
 0.7
 3.9
 0.6
0.2
 2.3
1.4
 1.2
0.6
 0.7
-0.1
 2.5
0.9
 4.8
4.3
18 PAX3 paired box 3 5077 0 4.1 3.9
 2.5
 3.3
7.1

1.0
-0.5
 2.9
2.0
19 FAM222A family with sequence similarity 222 member A 84915 0 4.0 3.5
 1.2
 3.5
 1.0
 0.7
 1.3
 -0.4
 1.0
 -0.6
20 IRX4 iroquois homeobox 4 50805 0 4.0 2.7
 1.2
 4.2
5.2
 4.5
 0.5
 5.6
2.3
 4.7
4.3
21 UNCX UNC homeobox 340260 0 3.9 3.8
3.1
3.8
 1.8
0.7
 3.7
3.2
22 RASSF10 Ras association domain family member 10 644943 0 3.9 3.0
 1.6
 3.9
 1.5
 2.9
2.4
 1.2
1.0
 0.8
0.5
 1.6
0.3
 2.5
2.3
23 ZIC2 Zic family member 2 7546 0 3.9 3.8
 1.2
 3.1
 2.1
1.4
 3.3
2.7
 0.2
-0.2
 0.2
-1.1
 0.8
0.3
 4.3
4.2
24 TFAP2C transcription factor AP-2 gamma 7022 0 3.9 3.4
 1.9
 3.4
 2.8
1.8
 5.5
5.1
 3.1
2.5
 2.3
2.0
 1.3
1.2
 3.8
3.6
25 HOXC13 homeobox C13 3229 0 3.9 2.8
 0.9
 4.0




1.7
26 NANOS1 nanos C2HC-type zinc finger 1 340719 0 3.9 2.5
 0.7
 4.3
 0.7
 0.1
 -0.3
2.4
-0.8
 1.6
0.1
27 PAX9 paired box 9 5083 0 3.9 3.4
 1.1
 3.4
3.4
1.5
 1.1
2.7
 1.5
1.1
28 MNX1 motor neuron and pancreas homeobox 1 3110 0 3.8 3.0
 1.8
 3.7



1.6
0.1
 1.9
29 TFAP2B transcription factor AP-2 beta 7021 0 3.8 4.4
 2.2
 2.2
 2.8
1.8
 5.5
5.1
 3.1
2.5
 2.3
2.0
 1.3
1.2
 3.8
3.6
30 EXOSC6 exosome component 6 118460 0 3.7 1.0
 0.7
 5.6
 1.2
0.9
 0.9
 1.5
 -0.3
31 C2CD4B C2 calcium dependent domain containing 4B 388125 0 3.7 0.5
 -0.0
 6.0
 1.3
 1.5
 0.8
-0.7
 -0.3

32 ZBTB7C zinc finger and BTB domain containing 7C 201501 0 3.7 2.8
 1.2
 3.8
 0.9
 1.5
 0.1
 1.9
 1.5
 1.5
33 LMX1B LIM homeobox transcription factor 1 beta 4010 0 3.7 3.6
 0.9
 3.0
5.0
 1.0
 -0.2
 0.4
-0.1
 1.7
1.1
34 OSR2 odd-skipped related transciption factor 2 116039 0 3.7 3.7
 1.6
 2.8
 0.4
-0.2
 1.9
1.9
 1.0
0.3
 2.7
2.3
 1.0
0.1
 1.8
1.7
35 NKX6-1 NK6 homeobox 1 4825 0 3.7 2.9
 0.0
 3.6
 -0.2
 1.4
 2.4
-0.3
0.5
-0.2
 4.0
2.8
36 SAP30 Sin3A associated protein 30 8819 0 3.7 2.4
 1.2
 4.1
 0.4
-0.8
 1.7
0.9
 1.1
0.9
 0.4
-0.6
 0.9
0.2
 -0.4
-0.9
37 AMH anti-Mullerian hormone 268 0 3.6 1.9
 1.1
 4.5
 -0.0
 -0.2
 0.5
 0.2
 1.2
 0.1
38 EPHB3 EPH receptor B3 2049 0 3.6 2.9
 2.1
 3.5
 2.0
0.6
 2.8
2.2
 1.6
0.8
 1.8
1.7
 1.8
1.0
 2.9
2.2
39 ZNF503 zinc finger protein 503 84858 0 3.6 2.8
 1.9
 3.6
 2.0
1.8
 5.0
2.0
 2.7
0.2
 1.5
1.4
 1.8
1.2
 5.0
4.2
40 HOXC10 homeobox C10 3226 0 3.6 3.3
 1.8
 3.1
 1.4
 2.2
 -0.6
 2.2
 -0.3
41 FAM43B family with sequence similarity 43 member B 163933 0 3.6 0.2
 0.5
 6.2
 0.7
-0.5
 0.6
0.1
 1.3
-0.8
 -0.8
 2.5
0.1
 1.1
0.3
42 EN2 engrailed homeobox 2 2020 0 3.6 3.2
 1.2
 3.1
3.4
 2.8
1.4
 4.3
3.6
43 HOXC11 homeobox C11 3227 0 3.6 3.0
 0.5
 3.3

-0.9

1.8
0.8
44 PITX1 paired like homeodomain 1 5307 0 3.6 3.4
 2.0
 2.8
 1.6
0.8
 3.8
2.3
 2.9
1.8
 2.6
0.7
 -0.0
-0.2
 4.2
2.3
45 EN1 engrailed homeobox 1 2019 0 3.6 4.5
 1.7
 1.7
6.2
 1.6
 0.5
 0.9
 4.3
46 CBX4 chromobox 4 8535 0 3.5 3.1
 1.7
 3.0
 0.9
 2.5
 0.3
 0.3
 0.8
 2.7
47 TMEM158 transmembrane protein 158 25907 0 3.5 0.9
 0.1
 5.2
 -0.2
 0.7
 0.1
0.3
 -0.5
48 TFAP2A-AS2 TFAP2A antisense RNA 2 109729173 0 3.5 3.5







49 FOXB1 forkhead box B1 27023 0 3.5 1.5
 1.1
 4.6
 2.6
0.4
 6.3
4.4
 1.8
1.6
 2.0
1.6
 1.9
1.4
 4.5
3.9
50 CASZ1 castor zinc finger 1 54897 0 3.5 3.0
 1.8
 3.1
 1.4
1.7
 0.3
-0.2
 1.9
 2.4
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