Orthologous genes in OrthoFinder**

Species Gene Description
 gga-u.3   SIK2   salt inducible kinase 2 
 gga-r.3   SIK2   salt inducible kinase 2 
 hsa-u.4   SIK2   salt inducible kinase 2 
 mmu-u.4   Sik2   salt inducible kinase 2 
 mcc-u.3   SIK2   salt inducible kinase 2 
 cfa-u.3   SIK2   salt inducible kinase 2 
 dre-u.3   sik2a   salt-inducible kinase 2a 
 dre-u.3   sik2b   salt-inducible kinase 2b 
 dme-u.3   Sik2   Salt-inducible kinase 2 

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Top 50 coexpressed genes to SIK2 (gga-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 gga4120   Ubiquitin mediated proteolysis  5 132 4.25
 gga4144   Endocytosis  4 224 2.28
 gga4910   Insulin signaling pathway  3 116 2.25
 gga4140   Autophagy - animal  3 129 2.12
 gga4010   MAPK signaling pathway  3 260 -

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gga:SIK2 (salt inducible kinase 2) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

gga-u.3
for
SIK2
gga-r.3
for
SIK2
hsa-u.4
for
SIK2
mmu-u.4
for
Sik2
mcc-u.3
for
SIK2
cfa-u.3
for
SIK2
dre-u.3
for
sik2a
dre-u.3
for
sik2b
dme-u.3
for
Sik2
1 GIT2 GIT ArfGAP 2 374035 5.8 3.1
 2.0
1.4
 1.6
0.6
 1.5
0.7
 2.5
0.1
 0.1
-0.7
 0.6
-0.3
 -0.8
2 ATP11C ATPase phospholipid transporting 11C 422254 5.5 3.0
 1.5
 1.5
 -0.1
 0.1
 1.1
 0.4
3 DYRK1A dual specificity tyrosine phosphorylation regulated kinase 1A 395233 5.4 2.9
 1.8
 1.5
 -0.5
 -0.6
 -0.9
-0.9
 1.8
1.3
 -0.1
4 KIAA0232 KIAA0232 422860 5.3 2.8
 0.2
 1.6
 1.9
 1.1
 -1.2
 1.3
5 MCM3AP minichromosome maintenance complex component 3 associated protein 424036 5.0 2.7
 1.6
 0.5
 0.4
 -0.0
 -1.4
 -0.4
6 PIAS1 protein inhibitor of activated STAT 1 427514 4.9 2.7
 1.1
0.9
 1.0
0.6
 0.9
0.7
 1.1
1.0
 1.2
0.5
 0.8
0.4
 0.5
7 BTBD9 BTB domain containing 9 421429 4.9 2.6
 1.8
 2.5
 -0.2
 2.7
 -0.0
 -0.4
 0.1
8 UVRAG UV radiation resistance associated 419091 4.9 2.6
 3.2
 -0.2
 2.5
 1.5
 0.1
 -0.9
 -0.5
9 TRAPPC9 trafficking protein particle complex 9 420312 4.8 2.6
 1.5
 2.2
 2.8
 2.9
 0.6
 0.2
 1.1
10 GPATCH2L G-patch domain containing 2 like 423368 4.8 2.6
 -0.2
-0.4
 0.5


11 ASB7 ankyrin repeat and SOCS box containing 7 415518 4.8 2.6
 0.3
 -0.4
 0.2
 -0.2
 0.5
 -0.9
12 LPGAT1 lysophosphatidylglycerol acyltransferase 1 421375 4.7 2.6
 0.8
 1.1
 0.7
 0.1
 -0.1
 0.9
13 LOC121107537 uncharacterized LOC121107537 121107537 4.7 2.6






14 LAMP2 lysosomal associated membrane protein 2 414800 4.7 2.5
 0.9
0.0
 -0.3
-0.8
 1.0
0.8
 0.3
-0.4
 1.2
0.9
 0.7
-0.5
 -1.1
15 UBR2 ubiquitin protein ligase E3 component n-recognin 2 421387 4.6 2.5
 1.3
 3.0
0.9
 0.2
-0.5
 0.4
0.2
 -0.6
-1.0
 0.7
0.3
 0.9
16 CAND2 cullin associated and neddylation dissociated 2 (putative) 416121 4.6 2.5
 0.1
-0.4
 -0.1
-0.9
 -0.5
-1.3
 -0.0
-1.3
 -0.2
-0.7
 0.4
0.3
 0.1
17 CBL Cbl proto-oncogene 374038 4.6 2.5
 4.1
2.3
 2.6
1.2
 1.8
1.4
 1.7
1.3
 0.3
0.1
 1.0
0.5
 -0.6
18 ACACA acetyl-CoA carboxylase alpha 396504 4.6 2.5
 3.7
1.2
 2.9
1.2
 1.3
1.1
 1.3
0.9
 1.2
-0.4
 2.3
2.1
 1.6
19 PRRC2B proline rich coiled-coil 2B 417177 4.6 2.5
 3.2
 0.4
 2.4
 1.1
 0.0
-0.2
 3.0
-0.5
20 ZDHHC8 zinc finger DHHC-type containing 8 416788 4.6 2.5
 3.3
0.7
 2.6
1.0
 1.4
0.9
 2.0
1.1
 0.5
0.0
 1.0
0.4
 0.2
21 TRAPPC11 trafficking protein particle complex 11 428748 4.5 2.5
 1.2
 0.2
 1.5
 -0.4
 0.4
 -0.8
 0.0
22 ANKHD1 ankyrin repeat and KH domain containing 1 416143 4.5 2.5
 4.3
1.5
 2.1
0.8
 2.8
1.1
 2.0
1.1
 1.0
 1.1
 0.3
23 CTSD cathepsin D 396090 4.5 2.5
 0.7
0.3
 0.2
0.1
 0.7
0.3
 1.0
0.0
 0.1
0.1
 -0.0
-0.5
 0.8
0.2
24 ZBTB11 zinc finger and BTB domain containing 11 418400 4.5 2.4
 0.3
 2.8
 1.5
 -0.6
 -0.4
 0.2
25 FECH ferrochelatase 374020 4.5 2.4
 -0.5
 0.6
 0.3
 -0.5
 2.0
 1.1
 -0.1
26 RAB8B RAB8B, member RAS oncogene family 415371 4.5 2.4
 0.3
-0.2
 1.1
-0.6
 0.2
-0.5
 2.0
-0.5
 1.0
0.5
 0.5
-0.1
 -0.1
-1.7
27 PNPLA2 patatin like phospholipase domain containing 2 431066 4.5 2.4
 1.9
 3.4
 1.7
 3.1
 0.1
-0.2
 1.2
1.0
 -0.1
-1.5
28 TBC1D22A TBC1 domain family member 22A 428128 4.5 2.4
 1.7
0.6
 0.2
-0.6
 1.0
-0.4
 0.7
-1.0
 0.5
-0.2
 -0.1
-1.3
 0.3
29 UBE3B ubiquitin protein ligase E3B 776286 4.4 2.4
 2.8
 2.2
 0.0
 1.9
 -1.5
 -0.3
 -0.2
30 ZBTB44 zinc finger and BTB domain containing 44 101751641 4.4 2.4
 2.3
 0.8
 -0.2
 1.9
 0.5
 -1.4
31 BRAF B-Raf proto-oncogene, serine/threonine kinase 396239 4.4 2.4
 1.8
 4.1
 1.0
 1.9
 -0.3
 -0.6
32 C2CD2L C2CD2 like 428233 4.3 2.4
 3.2
 1.2
 -1.7
 0.1
 -0.2
 0.8
33 ELMSAN1 ELM2 and Myb/SANT domain containing 1 423245 4.3 2.4
 1.7
 2.2
 0.5
 1.3
 0.2
 1.8
34 TNKS tankyrase 374252 4.3 2.4
 2.4
0.2
 2.9
2.0
 0.2
-0.2
 0.7
-0.4
 1.1
-0.9
 0.8
0.8
 1.5
35 MAP3K3 mitogen-activated protein kinase kinase kinase 3 419954 4.3 2.3
 0.9
0.5
 0.8
0.7
 2.0
0.1
 0.8
-0.0
 0.3
-0.9
 1.1
0.1
36 USP49 ubiquitin specific peptidase 49 419925 4.3 2.3
 0.4
 1.4
 -1.0
 1.4


37 FADS2 fatty acid desaturase 2 423122 4.3 2.3
 2.1
0.9
 1.5
-0.3
 0.4
-0.4
 -0.5
-0.8
 1.3
 -0.3
38 MTF1 metal regulatory transcription factor 1 428218 4.3 2.3
 1.8
 2.5
 0.1
 1.5
 -0.7
 -0.3
 0.7
39 SNX13 sorting nexin 13 420598 4.2 2.3
 0.3
 -0.6
 1.0
 0.6
 -1.7
 -1.2
40 ZC3H7B zinc finger CCCH-type containing 7B 417996 4.2 2.3
 2.7
 1.1
 1.3
 1.5


41 SLAIN2 SLAIN motif family member 2 422766 4.1 2.3
 1.7
 0.7
 0.6
 0.9
 0.1
 2.2
42 TMEM94 transmembrane protein 94 422124 4.1 2.3
 1.8
 1.7
 -0.5
 1.7
 -0.7
 -0.2
 -0.1
43 PARK2 parkin RBR E3 ubiquitin protein ligase 421577 4.1 2.2
 0.8
-1.2
 0.3
 2.4
 1.1
 -0.9
44 CCM2 CCM2 scaffolding protein 420410 4.1 2.2
 0.4
 0.1
 1.1
 -1.0
 -0.1
 -0.3
45 EPN2 epsin 2 416524 4.1 2.2
 0.5
-0.4
 0.1
-0.1
 -0.5
-0.8
 2.3
0.7
 1.6
1.3
 2.8
1.7
 -0.2
46 DENND1B DENN domain containing 1B 424351 4.1 2.2
 0.9
 1.3
0.5
 0.6
0.2
 2.5
-0.9
 0.4
0.1
 0.9
-0.8
 0.6
47 INTS6L integrator complex subunit 6 like 422239 4.1 2.2
 0.5
-1.3
 -0.0
 0.9
-0.4
 0.2
-0.8
 0.9
-0.1
 0.0
-0.8
 0.5
48 NFX1 nuclear transcription factor, X-box binding 1 420796 4.0 2.2
 1.7
 2.1
 2.8
 0.2
 0.6
 0.6
 0.8
49 PPM1B protein phosphatase, Mg2+/Mn2+ dependent 1B 421404 4.0 2.2
 -0.2
-0.5
 1.3
1.0
 1.2
-1.6
 -0.3
-0.4
 2.5
1.5
 2.2
2.0
 0.4
-0.2
50 ITCH itchy E3 ubiquitin protein ligase 419145 4.0 2.2
 1.1
-0.9
 -0.1
-0.5
 1.2
0.9
 1.7
1.3
 1.2
0.3
 0.7
0.5
 0.2
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