Orthologous genes in OrthoFinder**

Species Gene Description
 gga-u.3   RAPGEF5   Rap guanine nucleotide exchange factor 5 
 gga-r.3   RAPGEF5   Rap guanine nucleotide exchange factor 5 
 gga-u.3   RAPGEF4   Rap guanine nucleotide exchange factor 4 
 gga-u.3   RAPGEF3   Rap guanine nucleotide exchange factor 3 
 hsa-u.4   RAPGEF5   Rap guanine nucleotide exchange factor 5 
 hsa-u.4   RAPGEF3   Rap guanine nucleotide exchange factor 3 
 mmu-u.4   Rapgef5   Rap guanine nucleotide exchange factor (GEF) 5 
 mmu-u.4   Rapgef3   Rap guanine nucleotide exchange factor (GEF) 3 
 rno-u.3   Rapgef4   Rap guanine nucleotide exchange factor 4 
 rno-u.3   Rapgef5   Rap guanine nucleotide exchange factor 5 
 rno-u.3   Rapgef3   Rap guanine nucleotide exchange factor 3 
 mcc-u.3   RAPGEF4   Rap guanine nucleotide exchange factor 4 
 mcc-u.3   RAPGEF5   Rap guanine nucleotide exchange factor 5 
 mcc-u.3   RAPGEF3   Rap guanine nucleotide exchange factor 3 
 cfa-u.3   RAPGEF5   Rap guanine nucleotide exchange factor 5 
 cfa-u.3   RAPGEF4   Rap guanine nucleotide exchange factor 4 
 cfa-u.3   RAPGEF3   Rap guanine nucleotide exchange factor 3 
 dre-u.3   101885382   rap guanine nucleotide exchange factor 5-like 
 dre-u.3   rapgef5a   Rap guanine nucleotide exchange factor (GEF) 5a 
 dme-u.3   Epac   Exchange protein directly activated by cAMP 
 cel-u.3   epac-1   Rap guanine nucleotide exchange factor 1 
 spo-u.3   SPBC1539.06   putative acyl-coenzyme A binding protein 

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Top 50 coexpressed genes to RAPGEF5 (gga-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 gga4270   Vascular smooth muscle contraction  2 122 -
 gga230   Purine metabolism  2 125 -
 gga4514   Cell adhesion molecules  2 126 -
 gga4020   Calcium signaling pathway  2 225 -
 gga4010   MAPK signaling pathway  3 260 -

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gga:RAPGEF5 (Rap guanine nucleotide exchange factor 5) External Links;


Show/Hide Columns:        
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

gga-u.3
for
RAPGEF5
gga-r.3
for
RAPGEF5
gga-u.3
for
RAPGEF4
gga-u.3
for
RAPGEF3
hsa-u.4
for
RAPGEF5
hsa-u.4
for
RAPGEF3
mmu-u.4
for
Rapgef5
mmu-u.4
for
Rapgef3
rno-u.3
for
Rapgef4
rno-u.3
for
Rapgef5
rno-u.3
for
Rapgef3
mcc-u.3
for
RAPGEF4
mcc-u.3
for
RAPGEF5
mcc-u.3
for
RAPGEF3
cfa-u.3
for
RAPGEF5
cfa-u.3
for
RAPGEF4
cfa-u.3
for
RAPGEF3
dre-u.3
for
101885382
dre-u.3
for
rapgef5a
dme-u.3
for
Epac
cel-u.3
for
epac-1
spo-u.3
for
SPBC1539.06
1 PLEKHG1 pleckstrin homology and RhoGEF domain containing G1 421632 6.1 3.3
 0.5
 0.4

3.6
 2.1
 1.5
 2.9
 2.2
 -0.5
 1.3
 0.9
 3.4
 -0.2
 -0.2
 1.2
 1.6
 3.3

2 ADGRG1 adhesion G protein-coupled receptor G1 415633 5.3 2.9
 0.0
 2.7
 -0.4
 1.8
 0.2
 3.9
 -0.5
 1.0
 4.0
 -0.8
 -0.2
 2.9
 2.2
 0.4
 3.2
 1.6
 0.8


3 MCF2L MCF.2 cell line derived transforming sequence like 418748 5.3 2.9
 3.9
1.5
 1.0
0.6
 3.8
0.3
 2.4
-0.4
 2.2
0.6
 3.0
0.5
 1.5
0.7
 1.5
0.3
 2.8
1.0
 1.4
0.2
 2.1
0.1
 0.3
-0.4
 0.6
0.6
 1.5
0.1
 3.2
-1.3
 1.6
0.9
 1.6
1.4
 -0.0
 0.6
 -0.1
4 FAM84B family with sequence similarity 84 member B 770776 5.2 2.8
 0.1
 2.6
 0.7
 1.6
 1.1
 -0.4
 0.2
 1.8
 -0.0
 0.3
 0.5
 0.5
 -0.2
 -0.3
 -0.2
 -1.0
 -1.7


5 HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 424050 5.2 2.8
 2.2
 1.0
 1.4
 0.4

2.6
 4.3
 2.1
 0.9
 0.7
 0.9
 2.0
 2.2
 0.2
 1.1
0.7
 1.2
0.7
 -0.0

6 SOX7 SRY-box 7 771337 5.1 2.7
 0.9
0.8
 3.8
2.5
 3.0
1.4
 2.7
1.6
 3.1
2.8
 3.4
3.2
 1.1
0.3
 2.9
2.4
 3.6
2.7
 1.1
0.9
 2.0
1.7
 2.9
2.0
 1.8
1.6
 1.2
1.0
 2.7
2.2
 1.1
0.8
 2.9
1.9
 2.2
1.5
 1.3
1.2
 -0.5
-0.5
7 SASH1 SAM and SH3 domain containing 1 421621 4.9 2.7
 1.6
 0.3
 2.9
 2.0
 1.7
 2.0
 0.8
 0.0
 2.2
 0.3
 1.2
 2.0
 -0.6
 1.0
 0.5
 0.0
-0.5
 0.9
0.3


8 LOC423752 uncharacterized LOC423752 423752 4.9 2.7
 0.8
 1.1












0.9
 1.9


9 ADGRL4 adhesion G protein-coupled receptor L4 424546 4.9 2.6
 0.7
 1.4
 2.3
 1.8
 2.8
 3.3
 0.3
 2.5
 3.8
 1.0
 1.7
 1.2
 1.6
 1.4
 2.1
 0.1
 2.2
0.3
10 NOVA1 NOVA alternative splicing regulator 1 423300 4.9 2.6
 1.1
 1.0
 2.3
 1.2
 3.5
 3.3
 0.7
-0.0
 1.9
-0.0
 2.2
-0.5
 0.9
 1.2
 1.7
 1.3
0.2
 1.6
0.5
 2.2
0.5
 0.6
0.4
 3.6
-0.6
 1.5
 -0.7
11 VEGFRKDRL vascular endothelial growth factor receptor kdr-like 422316 4.8 2.6
 0.6
0.4
 1.4
1.3
 3.7
2.2
 1.9
1.1
 3.2
3.0
 3.1
2.8
 2.1
1.4
 3.2
1.6
 3.5
1.4
 1.4
-0.2
 1.5
1.2
 0.9
0.8
 3.4
1.0
 2.0
1.4
 2.7
1.7
 1.9
1.5
 2.9
2.3
 1.7

12 TMCC3 transmembrane and coiled-coil domain family 3 417905 4.7 2.5
 0.5
0.5
 1.8
1.2
 2.8
1.4
 1.3
0.7
 1.8
0.5
 1.8
0.8
 2.1
0.8
 2.1
1.3
 1.7
0.9
 0.8
0.3
 3.1
1.0
 2.2
1.2
 0.6
-0.4
 1.4
-0.0
 0.4
0.1
 0.4
0.2
 0.7
0.3
 0.8
 -0.3
13 ANGPT2 angiopoietin 2 395610 4.7 2.5
 0.9
 1.6
 2.8
 0.6
 1.6
 2.5
 0.3
 1.9
 2.1
 0.8
 2.0
 0.2
 3.4
 1.6
 1.1
 1.2
 0.4


14 PREX2 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 420172 4.6 2.5
 1.5
0.1
 0.5
-1.1
 3.7
0.4
 3.7
0.4
 3.4
1.0
 4.1
-0.3
 1.7
0.0
 1.1
1.1
 2.3
0.9
 0.7
0.6
 2.2
0.0
 0.9
0.5
 2.9
-1.0
 0.6
-0.1
 2.0
1.9
 -0.1
-0.4
 2.4
1.9


15 DOCK9 dedicator of cytokinesis 9 418779 4.5 2.4
 2.3
0.7
 1.5
0.6
 4.1
 2.3
0.2
 6.1
1.8
 3.0
0.9
 1.0
-0.1
 2.2
1.6
 1.6
0.6
 1.2
0.1
 3.6
0.5
 1.8
-0.2
 5.1
-0.4
 3.1
0.8
 1.1
0.9
 0.5
0.1
 1.4
0.6
 0.9
 -0.7
16 SLC9A3R2 SLC9A3 regulator 2 416550 4.5 2.4
 0.3
0.0
 3.7
0.9
 0.7
-0.3
 3.0
-1.3
 1.9
-1.7
 5.1
0.7
 -0.0
-0.6
 1.1
-1.2
 3.9
-1.0
 1.4
-0.2
 0.9
-0.5
 1.5
-0.3
 1.8
-1.1
 0.7
0.1
 4.2
0.4
 1.3
-0.3
 3.5
0.8
 -1.0
2.8
17 CNN3 calponin 3 424485 4.4 2.4
 0.5
-0.1
 1.4
1.0
 1.5
0.4
 0.5
-0.0
 0.0
-0.3
 1.2
0.1
 0.6
0.3
 0.7
0.3
 1.1
0.8
 0.8
-0.2
 1.0
0.7
 1.6
1.2
 0.6
0.4
 0.2
-0.6
 0.6
0.2
 2.7
1.0
 1.3
1.3
 0.6
-1.3
 -1.0
-1.0
 0.6
18 PDZD2 PDZ domain containing 2 427421 4.4 2.4
 1.5
 0.5
 2.5
 3.1
 2.1
 2.5
 -0.4
 0.5
 2.0
 0.9
 0.0
 0.7
 1.1
 -0.7
 1.3
 0.7
 -0.4


19 FAR2 fatty acyl-CoA reductase 2 419043 4.4 2.4
 1.0
0.9
 0.8
-0.1
 1.2
-0.2
 1.0
0.6
 0.9
0.4
 -0.3
-0.4
 1.2
0.7
 1.6
0.9
 -0.2
-0.5
 0.1
-0.7
 0.8
0.7
 0.5
-1.9
 1.2
-0.1
 0.0
-0.4
 0.9
-0.5
 2.1
0.4
 -0.4
-0.8
 1.2
0.5
 0.5
 0.3
0.2
20 CDC42BPA CDC42 binding protein kinase alpha 416746 4.4 2.4
 2.0
-0.2
 1.8
0.5
 2.2
1.0
 1.9
1.5
 3.4
1.2
 1.8
1.6
 0.6
0.3
 0.7
0.6
 2.4
1.8
 0.5
-0.1
 1.1
0.4
 1.3
0.2
 2.5
0.1
 2.0
1.6
 1.1
0.4
 1.7
0.2
 1.6
1.2
 0.8
 0.9
21 EPB41L2 erythrocyte membrane protein band 4.1 like 2 421703 4.4 2.4
 0.6
 -0.0
 2.3
 1.6
 2.2
 1.2
 0.2
 3.7
 1.4
 1.6
 2.9
 -0.1
 -0.4
 -0.6
 -0.2
 -0.3
-0.3
 2.3
0.1


22 JAM2 junctional adhesion molecule 2 418476 4.3 2.3
 1.5
0.6
 1.7
1.7
 1.6
1.1
 0.8
-0.1
 1.8
0.9
 2.5
1.5
 1.5
1.0
 3.5
2.5
 4.0
2.7
 0.2
0.2
 1.3
0.7
 0.8
0.5
 2.3
0.9
 1.1
0.3
 1.9
0.7
 0.3
-0.0
 1.6
0.3
2.8
23 ADGRA1 adhesion G protein-coupled receptor A1 423825 4.3 2.3
 2.0
0.6
 0.9
-0.1
 0.4
-0.5
 0.2
-0.8
 0.3
0.3
 2.1
-0.1
 0.7
-0.7
 0.9
-0.2
 0.1
-0.1
 0.5
0.2
 0.5
0.5
 0.7
0.5
 -0.2
-2.3
 0.5
-1.2
 0.3
-0.9
 0.3
0.2
 -0.8
-0.9
 0.3

24 ICA1 islet cell autoantigen 1 420581 4.3 2.3
 1.0
 0.0
 0.2
 -0.5
 4.2
 2.2
 0.5
0.2
 2.7
0.5
 0.7
0.5
 0.6
0.6
 1.0
-0.4
 0.9
-0.1
 0.3
 2.1
 2.0
 0.3
-0.4
 1.0
0.1
 1.0
 1.3
25 TJP2 tight junction protein 2 395751 4.2 2.3
 0.9
 -0.6
 2.1
 1.8
 1.3
 0.0
 0.0
 0.4
 1.1
 -1.0
 1.3
 1.0
 1.4
 0.6
 0.2
 -0.4
 2.3


26 GUCY1B3 guanylate cyclase 1 soluble subunit beta 422408 4.2 2.3
 2.4
 -0.2
 1.2
 0.5
 3.2
 -0.4
 1.1
 4.1
 0.9
 1.3
 0.1
 -0.2
 2.5
 1.7
 1.3
 0.6
 1.4
 1.3

27 CARMIL1 capping protein regulator and myosin 1 linker 1 421002 4.2 2.3
 1.2
0.8
 0.3
-0.6
 2.5
0.4
 0.4
0.1
 1.1
-1.1
 1.0
0.2
 0.7
-0.6
 1.2
-0.6
 1.3
1.3
 0.6
-0.2
 0.2
-0.5
 0.3
-0.6
 1.6
 -0.3
 0.1
 1.1
-0.3
 0.2
-0.2
 2.6
 0.4
28 BTBD3 BTB domain containing 3 427688 4.2 2.3
 2.0
-0.3
 0.8
0.3
 2.1
-0.2
 0.7
-0.5
 2.4
0.2
 -0.2
-1.6
 1.3
-0.5
 2.5
-1.3
 -0.4
-0.4
 1.8
0.4
 1.6
-1.5
 -0.1
-0.8
 1.0
0.8
 0.4
0.3
 0.0
-0.1
 2.4
1.1
 1.9
0.9
 0.5

29 ZSWIM6 zinc finger SWIM-type containing 6 770670 4.2 2.3
 0.1
0.0
 -0.6
-1.4
 1.3
0.8
 2.0
-0.5
 1.8
1.1
 -0.7
-0.7
 0.9
0.7
 3.0
1.0
 1.2
0.6
 0.0
-0.1
 0.8
0.0
 0.5
-0.3
 2.0
0.6
 0.8
0.2
 0.7
0.0
 0.5
0.3
 0.5
-0.5


30 ZNF366 zinc finger protein 366 431599 4.0 2.2
 0.3
 2.8
 1.3
 3.3
 2.9
 3.1
 1.3
 2.6
 2.1


1.0
 0.8
 1.5
 1.3
 0.2


31 LDB2 LIM domain binding 2 395631 4.0 2.2
 0.0
-0.8
 1.8
0.4
 -1.1
 -0.1
 4.1
-0.8
 1.5
1.3
 1.2
-1.4
 3.3
-1.3
 1.3
0.4
 0.5
-0.3
 1.9
0.4
 1.1
0.5
 1.7
-0.7
 0.7
-1.3
 1.5
0.7
 1.4
0.6
 0.8
-0.2
 0.7
 1.8
32 PCDH19 protocadherin 19 422263 4.0 2.2
 0.2
 1.4
 0.2
 0.6
 0.5
 0.8
 -0.3
 2.1
 2.1
 -0.6
 -0.6
 -0.2
 1.5
 1.1
 1.6
 0.3
 2.9


33 NBEA neurobeachin 395195 3.9 2.1
 1.2
0.5
 0.8
-0.3
 1.9
0.4
 0.3
-0.3

0.4
-0.4
 3.2
-0.4
 -0.2
-0.6
 -0.6
-0.7
 0.1
0.0
 -0.0
-2.2
 2.6
-1.0
 2.6
-0.4
 0.1
-0.9
 0.6
0.4
 1.9
0.5
1.3
 -0.1
34 GUCY1A2 guanylate cyclase 1 soluble subunit alpha 2 771678 3.9 2.1
 -0.7
 2.0
 1.5
 -0.1
 1.4
 -0.4


1.1
 2.1
 -0.6
 3.7
 1.5
 1.6
 2.2
 -1.4
 0.6

35 MTCL1 microtubule crosslinking factor 1 426050 3.9 2.1
 0.5
 0.3
 0.7
 -0.6
 0.2
 0.2
 2.0
 0.2
 0.3
 0.7
 -0.2
 -0.6
 0.7
 3.0
 -0.6
 1.8
 -0.3


36 ARL4A ADP ribosylation factor like GTPase 4A 420589 3.9 2.1
 0.3
0.1
 -0.3
-0.7
 -0.2
-0.4
 0.3
-1.2
 1.3
0.9
 0.7
-0.5
 0.1
-0.2
 3.2
1.4
 2.3
-0.2
 0.4
-0.2
 0.2
-0.8
 -0.0
-0.5
 2.3
0.8
 0.5
-0.3
 1.3
1.1
 0.3
-0.0
 1.0
0.1
 -0.7

37 CRIM1 cysteine rich transmembrane BMP regulator 1 395067 3.9 2.1
 0.1
 1.0
 1.0
 1.4
 1.4
 0.9
 1.0
 3.5
 2.0
 0.2
 0.5
 -1.7
 1.2
 1.1
 -0.4
 1.0
 2.0
 1.1
0.4
 1.1
 0.6
38 HSPA12A heat shock protein family A (Hsp70) member 12A 423917 3.9 2.1
 1.0
 -0.3
 0.3
 0.3
 3.1
 0.4
 1.2
 1.1
 1.6
 1.4
 1.0
 0.8
 -0.6
 -0.4
 -0.5
 1.4
 -0.3


39 PHLDB2 pleckstrin homology like domain family B member 2 418418 3.9 2.1
 -0.8
 0.3
 0.2
 0.4
 -0.8
 1.3
 0.2
 -1.3
 0.3
 0.3
 2.2
 1.2
 0.4
 -0.2
 0.2
 0.8
-0.4
 0.8
-0.1
 0.3
-1.3
40 PTPRM protein tyrosine phosphatase, receptor type M 421049 3.9 2.1
 1.7
0.5
 2.0
1.6
 1.2
0.2
 1.3
0.6
 3.1
2.5
 2.3
1.6
 1.6
1.3
 1.4
1.3
 2.5
1.2
 0.7
0.7
 1.1
1.0
 1.8
0.6
 2.4
1.7
 1.8
0.1
 1.6
1.5
 1.5
1.2
 1.9
1.3


41 SORBS2 sorbin and SH3 domain containing 2 422719 3.9 2.1
 1.6
 1.7
 2.9
 0.7
 1.2
 -0.6
 4.5
 1.8
 0.3
 2.6
 0.9
 0.3
 0.2
 1.4
 0.5
 0.7
-0.4
 1.0
-0.6


42 DOCK4 dedicator of cytokinesis 4 417779 3.8 2.1
 1.8
1.1
 2.0
1.1
 2.9
2.0
 1.8
1.7
 2.8
1.7
 1.2
0.7
 1.6
0.9
 2.3
1.3
 1.2
0.2
 1.3
0.6
 1.4
0.6
 0.3
-0.0
 2.6
2.2
 1.3
0.6
 0.5
0.3
 3.0
1.0
 0.7
0.6
 1.3
1.2
 1.8
43 SPTBN1 spectrin beta, non-erythrocytic 1 421216 3.8 2.1
 2.9
1.0
 1.1
-0.2
 2.6
2.4
 2.4
1.5
 2.4
0.7
 2.2
0.1
 1.7
0.5
 1.8
1.0
 2.3
0.8
 0.9
0.5
 3.6
0.3
 1.2
0.1
 1.8
0.5
 2.1
1.0
 1.7
1.1
 0.7
0.4
 2.2
-0.5
 2.0
 1.4
44 PTPRR protein tyrosine phosphatase, receptor type R 771985 3.8 2.1
 1.5
-0.2
 1.6
0.3
 -0.1
-0.3
 0.7
0.3
 2.2
-0.1
 1.2
0.4
 0.0
-0.4
 0.7
-1.0
 0.6
0.0
 0.7
-1.1
 -0.1
-0.6
 -0.4
-0.8
 0.3
0.2
 1.5
0.1
 2.0
-0.2
 -0.1
 0.7


45 PTPRG protein tyrosine phosphatase, receptor type G 374208 3.8 2.1
 0.1
-0.2
 0.4
-0.8
 2.7
 0.7
 1.7
 1.1
 2.4
 2.3
 1.7
 2.7
 2.7
 -0.5
 -0.3
 1.5
 1.0
 -0.2
-0.8
 2.9
-1.1
 2.5
 3.7
 -0.7
46 HEY2 hes related family bHLH transcription factor with YRPW motif 2 421718 3.8 2.1
 -0.1
-0.7
 1.1
0.4
 1.2
1.1
 0.4
-0.6
 1.0
0.2
 1.2
0.3
 2.6
0.3
 2.6
0.2
 2.6
0.6
 1.9
0.2
 1.6
0.2
 1.4
0.8
 1.4
1.0
 0.2
-0.4
 1.7
0.2
 -0.7
-0.8
 0.8
-0.5
 0.4

47 STEAP2 STEAP2 metalloreductase 420541 3.8 2.1
 1.4
 0.3
 1.9
 0.3
 -0.4
 1.0
 -1.3
 -0.2
 1.8
 0.3
 0.5
 0.3
 2.2
 1.0
 -0.0
 2.7
 -0.5


48 GAS6 growth arrest specific 6 418737 3.8 2.1
 -0.0
 0.1
 0.3
 0.8
 1.8
 1.0
 0.1
 -0.2
 0.0
 0.6
 0.0
 2.6
 -0.2
 0.7
 1.3
 -0.2
 0.2


49 LOC776273 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1-like 776273 3.8 2.1
 2.2
 3.4
1.6
 1.7
1.3
 0.8
0.5
 2.2
1.4
 2.9
0.9
 -0.6
-1.0
 0.7
0.4
 3.3
0.8
 -0.1
-0.5
 -0.2
-0.3
 1.6
0.9
 0.6
-0.9
 -0.0
-1.4
 0.6
-0.2
 0.8
-0.5
 -0.4
-1.1
 -0.4
 0.7
50 MYO10L myosin-X-like 429030 3.8 2.1
 1.4
 0.7












0.1
 -0.6


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