Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3   aco1   aconitase 1, soluble 
 dre-r.3   aco1   aconitase 1, soluble 
 dre-m.5   aco1   aconitase 1, soluble 
 dre-u.3   ireb2   iron-responsive element binding protein 2 
 hsa-u.4   IREB2   iron responsive element binding protein 2 
 hsa-u.4   ACO1   aconitase 1 
 mmu-u.4   Ireb2   iron responsive element binding protein 2 
 mmu-u.4   Aco1   aconitase 1 
 rno-u.3   Ireb2   iron responsive element binding protein 2 
 rno-u.3   Aco1   aconitase 1 
 gga-u.3   IREB2   iron responsive element binding protein 2 
 gga-u.3   ACO1   aconitase 1, soluble 
 mcc-u.3   IREB2   iron responsive element binding protein 2 
 mcc-u.3   ACO1   aconitase 1 
 cfa-u.3   ACO1   aconitase 1 
 cfa-u.3   IREB2   iron responsive element binding protein 2 
 dme-u.3   Irp-1A   Iron regulatory protein 1A 
 dme-u.3   Irp-1B   Iron regulatory protein 1B 
 cel-u.3   aco-1   putative cytoplasmic aconitate hydratase 
 spo-u.3   hcs1   3-hydroxy-3-methylglutaryl-CoA synthase 

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Top 50 coexpressed genes to aco1 (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre4144   Endocytosis  6 324 3.86
 dre1200   Carbon metabolism  4 133 3.50
 dre1240   Biosynthesis of cofactors  4 179 3.01
 dre5132   Salmonella infection  4 306 2.17
 dre3320   PPAR signaling pathway  3 84 2.94

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dre:aco1 (aconitase 1, soluble) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dre-u.3
for
aco1
dre-r.3
for
aco1
dre-m.5
for
aco1
dre-u.3
for
ireb2
hsa-u.4
for
IREB2
hsa-u.4
for
ACO1
mmu-u.4
for
Ireb2
mmu-u.4
for
Aco1
rno-u.3
for
Ireb2
rno-u.3
for
Aco1
gga-u.3
for
IREB2
gga-u.3
for
ACO1
mcc-u.3
for
IREB2
mcc-u.3
for
ACO1
cfa-u.3
for
ACO1
cfa-u.3
for
IREB2
dme-u.3
for
Irp-1A
dme-u.3
for
Irp-1B
cel-u.3
for
aco-1
spo-u.3
for
hcs1
1 gusb glucuronidase, beta 571441 6.4 3.3
-1.5
 -0.5
 0.3
 -0.3
 1.2
 1.2
 1.9
 0.1
 2.3
 0.6
 0.0
 2.4
 0.1
 3.9
-1.3
 1.6
1.3
 1.3
 1.7
2 ermp1 endoplasmic reticulum metallopeptidase 1 101883637 6.1 3.2
0.6
 1.2
 2.7
 0.2
 1.2
 1.8
 1.3
 -1.4
 1.7
 -0.2
 2.3
 2.4
 1.1
 1.4
0.6
 2.2
1.3
 3.4
2.3
3 dera deoxyribose-phosphate aldolase (putative) 450077 5.6 4.0
 1.2
 0.2
 -0.8
 1.8
 2.0
 4.2
 -0.6
 3.0
 -1.7
 2.5
 -0.7
 1.1
 1.5
 1.2
 2.9
 1.2
 2.4
4 slc27a4 solute carrier family 27 member 4 550432 5.5 2.9
0.5
0.4
 0.3
0.2
 1.5
1.2
 0.9
0.7
 1.9
1.1
 0.7
0.6
 2.5
1.3
 -0.2
-0.4
 2.8
1.1
 0.0
-1.1
 1.3
1.2
 2.1
1.1
 0.9
0.8
 2.6
1.1
 3.9
1.2
 -0.4
-0.5
 -0.4
5 arhgap18 Rho GTPase activating protein 18 100004252 5.5 2.9
0.1
-0.7
 1.7
-1.1
 1.8
0.5
 1.3
-0.6
 1.6
0.6
 1.6
0.1
 1.5
0.1
 1.5
0.8
 1.6
0.9
 0.9
0.5
 2.1
0.2
 2.4
1.7
 0.5
0.3
 -0.7
 0.7

6 aldh3a2b aldehyde dehydrogenase 3 family, member A2b 447920 5.4 2.8
-0.1
-0.6
 0.0
 3.3
0.2
 3.1
-0.1
 2.2
0.2
 1.2
-0.3
 5.2
0.6
 1.1
-1.2
 5.8
0.2
 0.5
0.1
 2.8
0.3
 0.1
-1.0
 0.6
-1.3
 1.7
 5.4
 3.7
-0.2
 2.8
0.5
7 pi4kaa phosphatidylinositol 4-kinase, catalytic, alpha a 556956 5.1 2.7
1.0
-0.2
 1.3
 1.3
 1.6
 1.4
 -0.2
 2.3
 1.4
 -0.8
 1.2
 1.2
 1.9
 2.0
 1.9
 2.0
 1.2
 0.9
8 LOC100333227 carnitine O-palmitoyltransferase 1, liver isoform-like 100333227 5.1 2.7
0.6
0.1
 1.2
-0.4
 0.3
0.1
 1.7
 2.2
0.2
 2.2
0.3
 4.4
1.4
 -0.2
 2.3
 0.1
0.1
 0.7
-1.0
 0.3
-1.1
 0.0
-0.3
 -0.3
 3.1
 -1.8
9 slc25a1b slc25a1 solute carrier family 25 member 1b 795332 5.0 2.6
-0.7
-1.5
 0.3
 4.7
 0.7
 4.6
 -0.6
 2.9
 -1.0
 3.4
 -0.1
 1.5
 3.4
 1.1

4.0
-0.7
 -0.4
10 zgc:100918 zgc:100918 449549 4.9 2.6
1.4
-0.1
 -0.6
 1.1
 0.7
 0.8
 1.1
 1.4
 2.4
 0.8
 1.7
 1.9
 1.0
 0.6
 -0.2
 0.1
 -0.8
11 actr2b actin related protein 2b 554861 4.8 2.5
-0.1
-0.9
 1.5
 0.9
 1.9
 -0.7
 1.2
 1.0
 0.2
 1.9
 3.1
 0.6
 -1.1
 0.2
 0.0
 0.8
 0.1
12 pcyox1 prenylcysteine oxidase 1 550289 4.8 2.5
0.6
 0.1
 5.3
 0.0
 3.7
 1.1
 2.2
 0.6
 2.0
 -0.0
 5.0
 0.3
 0.4



13 appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 571540 4.8 2.5
-1.1
 1.2
 0.5
 2.7
 -0.4
 1.8
 -1.1
 1.4
 -1.3
 1.6
 1.7
 -0.2
 0.3



14 vcpip1 valosin containing protein (p97)/p47 complex interacting protein 1 570582 4.7 2.5
1.6
 2.3
 0.6
 3.5
 -0.3
 6.3
 -0.7
 2.0
 -0.3
 3.4
 0.9
 -0.1
 0.4



15 exoc4 exocyst complex component 4 559866 4.7 2.5
0.8

0.7
 0.7
 1.1
 1.6
 0.8
 1.6
 -0.1
 0.6
 -0.2
 0.2
 4.6
 1.2
 0.3
16 snx27a sorting nexin 27a 566205 4.7 2.5
3.0
-0.1
 3.3
 1.5
 1.9
 0.1
 -1.2
 0.8
 1.5
 1.5
 0.7
 0.3
 0.6
 1.0
 1.2
 -0.3
 -0.6
17 man1b1b mannosidase, alpha, class 1B, member 1b 556237 4.6 2.4
0.4
0.3
 -1.2
 0.9
 -0.9
 0.0
 0.3
 -0.4
 0.6
 2.8
 0.7
 1.6
 1.4
0.3
 1.6
-0.8
 0.3
 -0.1
 2.5
-0.7
18 hic2 hypermethylated in cancer 2 359828 4.6 2.4
-1.0
 1.0
 -1.0
 0.0
 0.1
 -0.7
 -0.6
 0.6
 0.4
 0.9
 -1.3
 -0.6
 0.2



19 pparg peroxisome proliferator-activated receptor gamma 557037 4.6 2.4
-0.5
 -0.1
 1.1
 -0.1
 2.4
 0.0
 0.6
 -1.8
 0.6
 -0.5
 0.6
 2.0
 0.2



20 dctn1a dynactin 1a 407638 4.5 2.4
-0.6
-0.9
 -0.9
 2.1
 0.4
 -0.5
 -2.7
 0.6
 0.4
 0.7
 -0.3
 1.8
 0.3
 1.1
 1.5
 1.3
 -0.5
 1.2
21 ogdha oxoglutarate dehydrogenase a 564552 4.5 2.4
2.6
0.9
 0.5
0.4
 2.2
0.1
 1.1
0.6
 2.8
-0.5
 0.2
-0.9
 3.6
0.9
 0.8
-0.3
 1.0
 -0.1
-1.5
 2.9
0.9
 2.1
-0.4
 0.9
-0.0
 0.8
 2.1
 4.1
22 pcyt2 phosphate cytidylyltransferase 2, ethanolamine 450016 4.5 2.4
1.8
 -0.9
 2.4
 0.4
 2.7
 0.0
 1.1
 -0.1
 1.5
 -1.3
 2.5
 2.2
 1.2
 0.3
 1.7
 -0.2
-2.0
 1.0
23 LOC101884968 regulator of microtubule dynamics protein 2-like 101884968 4.5 2.4
1.4
-1.2
 0.7
 1.7
 0.3
 3.3
 0.0
 0.9
 2.0
 1.4
 -0.4
 2.0
 1.8
 0.9



24 ehd3 EH-domain containing 3 562949 4.4 2.3
0.8
0.4
 -0.4
-0.5
 1.2
0.8
 -0.2
-0.5
 1.4
-0.0
 0.7
-0.3
 1.1
-0.0
 0.2
-0.8
 1.2
1.0
 0.8
0.4
 1.4
0.0
 2.6
1.6
 -0.4
-1.0
 1.9
 1.4
 1.5
25 man1a1 mannosidase, alpha, class 1A, member 1 566078 4.4 2.3
2.2
1.1
 1.6
1.5
 1.6
0.5
 1.5
1.3
 1.3
0.6
 3.7
1.2
 1.2
0.1
 0.4
-0.7
 1.9
0.2
 1.2
-0.3
 1.5
-0.0
 0.5
0.1
 1.0
-0.4
 0.7
-0.1
 0.8
0.1
 1.0
0.0
26 pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 404211 4.4 2.3
1.1
-0.1
 0.8
-0.9
 1.5
0.5
 1.8
-0.1
 2.0
1.2
 2.1
1.3
 0.7
0.5
 -0.3
-0.5
 0.7
-0.9
 1.8
0.8
 1.7
1.0
 0.7
-0.0
 0.6
-0.5
 0.9
 0.2
 -0.8
27 idh1 isocitrate dehydrogenase (NADP(+)) 1 100006589 4.4 2.2
 1.8
 0.1
-0.1
 1.4
0.8
 5.5
1.8
 2.4
0.3
 8.1
1.5
 2.0
-1.7
 5.9
0.9
 -0.3
-0.8
 5.0
0.2
 0.6
0.1
 2.9
2.4
 4.2
1.2
 1.3
1.2
 -0.6
 9.9
 6.8
5.9
28 si:ch73-22o12.1 si:ch73-22o12.1 560816 4.4 2.3
-0.7
-1.5
 0.7
-0.6
 0.4
0.0
 0.7
-1.2
 0.8
0.1
 1.2
0.3
 0.1
0.1

1.2
-0.0
 1.1
-0.2
 0.2
-0.6
 0.6
0.6



29 rc3h1b ring finger and CCCH-type domains 1b 558213 4.3 2.3
1.0
0.8
 5.5
1.8
 -0.5
-0.7
 4.3
1.5
 -0.9
-1.9
 5.6
3.1
 -0.6
-1.6
 3.1
0.9
 0.3
-0.8
 2.2
-0.3
 -0.4
-0.7
 0.1
-0.3
 2.5
-0.5
 1.0
 0.7
 0.4
30 ugp2a UDP-glucose pyrophosphorylase 2a 555748 4.3 2.3
1.1
-0.0
 0.7
 2.2
 0.9
 1.5
 1.0
 0.8
 1.0
 1.0
 0.7
 4.9
 1.7
 1.4
 -0.9
 3.6
 1.1
31 kat2b K(lysine) acetyltransferase 2B 563942 4.3 2.3
0.4
-0.7
 -1.3
-1.7
 -0.5
-0.5
 2.6
-2.0
 0.5
-1.3
 1.9
-1.1
 -0.3
-0.8
 0.1
-0.6
 0.1
-0.4
 1.2
-0.3
 1.1
-0.8
 -0.4
-0.6
 0.3
0.1
 2.9
 1.5
 0.1
32 rab8a RAB8A, member RAS oncogene family 571897 4.2 2.2
0.4
-0.2
 2.6
-0.1
 2.6
1.1
 0.3
-0.2
 1.6
1.3
 2.3
-0.6
 1.5
1.5
 1.7
0.9
 0.9
0.8
 3.7
0.5
 2.8
1.5
 0.4
0.2
 1.1
0.5
 0.6
-1.2
 0.8
0.6
 -0.4
-2.1
33 camk2b1 calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 562064 4.2 2.2
0.9
0.8
 0.6
0.0
 0.6
-0.4
 0.2
-0.1
 -0.3
-0.8
 1.1
-0.4
 0.6
0.6
 0.6
0.1
 -1.3
-1.4
 2.1
-0.1
 1.5
0.6
 -0.2
-0.6
 1.9
0.8
 0.6
 0.1

34 szt2 SZT2 subunit of KICSTOR complex 571986 4.2 2.2
0.1
-0.1
 -0.1
 -0.3
 1.5
 0.8
 1.3
 2.2
 1.8
 0.0
 2.0
 0.4
 -0.4
 1.1

-0.4
35 shmt2 serine hydroxymethyltransferase 2 (mitochondrial) 100144628 4.2 2.6
 1.3
 2.4
0.7
 0.1
-0.1
 2.9
0.9
 0.3
0.2
 2.2
2.0
 0.5
0.3
 2.2
0.3
 -0.1
 2.4
 -0.0
-0.4
 1.0
0.7
 2.1
1.6
 1.4
0.1
 3.6
 2.4
 3.0
36 zbtb10 zinc finger and BTB domain containing 10 566269 4.2 2.2
0.0
 -0.6
 -1.0
 1.0
 -1.1
 2.6
 0.5
 0.1
 1.6
 -1.0
 -0.9
 0.9
 1.7



37 itchb itchy E3 ubiquitin protein ligase b 100330031 4.2 2.2
1.0
0.6
 4.6
1.2
 -0.1
-0.3
 3.3
1.3
 2.1
1.8
 4.3
1.3
 0.8
0.0
 0.3
0.3
 0.2
0.0
 2.2
2.0
 1.0
0.6
 0.9
0.8
 2.2
1.5
 0.4
 0.2
 -0.6
38 fermt2 FERM domain containing kindlin 2 553051 4.2 2.2
-0.6
 0.2
 1.3
 0.6
 0.4
 1.4
 2.2
 0.3
 0.6
 0.1
 0.4
 1.8
 1.2
 1.3
-0.9
 2.0
-0.8
 2.1
39 pard6b par-6 partitioning defective 6 homolog beta (C. elegans) 100124652 4.2 2.2
1.0
 0.4
 -1.0
 0.4
 1.1
 1.1
 -0.2
 -0.5
 -0.9
 -0.3
 -0.5
 -0.7
 0.5
 0.6
 -1.0

40 acvr1bb activin A receptor type 1Bb 559222 4.1 2.2
1.4
1.3
 3.5
3.4
 1.9
1.7
 1.0
1.0
 1.2
0.6
 3.5
3.0
 2.0
1.6
 2.1
1.4
 1.9
0.5
 1.3
1.2
 1.9
1.0
 1.5
1.2
 1.0
0.9
 0.2
-0.5
 -0.1
-0.4
 1.5
 -0.5
41 shroom1 shroom family member 1 559364 4.1 2.2
-0.4





1.2
 1.4







42 acoxl acyl-CoA oxidase-like 569104 4.1 2.2
-0.6

-0.2
 -0.3





-1.2
 -1.1



43 tbc1d9b TBC1 domain family member 9B 100332046 4.1 2.2
2.1
-0.6
 0.8
0.3
 2.5
1.1
 2.5
0.6
 0.4
0.3
 2.9
0.2
 1.2
0.8
 0.9
0.5
 1.1
0.6
 1.3
0.9
 3.5
1.9
 2.5
2.2
 1.1
0.2
 1.2
 1.2
 -1.3
44 ndrg2 NDRG family member 2 494050 4.1 2.2
0.3
0.2
 0.7
0.7
 1.6
0.8
 0.2
-0.3
 0.7
-0.1
 -0.0
-0.3
 1.4
0.3
 -0.1
-1.2
 1.1
0.3
 0.4
0.0
 1.7
1.0
 1.1
0.7
 1.7
1.2
 0.1
 0.3
 -0.7
45 cat catalase 30068 4.1 2.5
 1.3
 0.6
 -0.7
 4.0
 0.7
 7.4
 1.4
 5.0
 1.3
 4.0
 -0.9
 1.0
 2.8
 0.3
 3.4
1.3
 4.2
0.3
 0.1
-0.0
46 fbxl17 F-box and leucine-rich repeat protein 17 795023 4.0 2.1
-0.6
 1.6
 0.1
 1.5
 -0.4
 0.5
 -0.6
 0.8
 1.1
 1.5
 0.3
 0.9
 -1.1



47 gipc1 GIPC PDZ domain containing family, member 1 445568 4.0 2.1
0.5
-0.7
 -0.5
-0.8
 1.1
-0.4
 -0.5
-0.8
 -0.3
-0.4
 0.2
0.2
 1.4
-0.2
 0.1
-0.6
 0.1
-0.4
 -0.9
-0.9
 0.4
0.1
 0.6
-0.2
 -0.3
-0.4
 -1.2
 1.5
 0.0
-0.5
48 pum2 pumilio RNA-binding family member 2 567494 4.0 2.1
1.8
0.8
 6.0
2.9
 0.7
-1.0
 6.9
0.9
 1.5
-2.2
 3.4
0.6
 1.0
-1.0
 2.4
2.1
 0.7
0.1
 3.6
2.5
 1.7
-0.1
 0.8
0.6
 1.8
0.4
 -0.6
 0.3
 2.1
0.2
 1.2
49 epg5 ectopic P-granules autophagy protein 5 homolog (C. elegans) 569543 4.0 2.1
1.6
 1.6
 2.9
 3.6
 1.0
 1.0
 -0.0
 2.2
 0.6
 3.0
 0.6
 -0.2
 0.8
 2.3
 1.1
 0.3
50 gfpt1 glutamine--fructose-6-phosphate transaminase 1 567861 4.0 2.1
0.2
-0.7
 2.3
-0.4
 2.2
2.0
 0.6
-0.3
 0.9
0.2
 1.8
-0.1
 -0.0
-0.8
 2.6
-0.2
 0.2
-0.5
 2.9
-0.9
 2.8
0.4
 2.1
-0.3
 0.7
-0.3
 3.2
0.1
 1.4
0.4
 1.3
-0.6
 -0.8
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