Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3   adora2b   adenosine A2b receptor 
 dre-r.3   adora2b   adenosine A2b receptor 
 dre-u.3   adora4a   adenosine A4 receptor a 
 hsa-u.4   ADORA1   adenosine A1 receptor 
 mmu-u.4   Adora2a   adenosine A2a receptor 
 mmu-u.4   Adora1   adenosine A1 receptor 
 rno-u.3   Adora1   adenosine A1 receptor 
 rno-u.3   Adora2b   adenosine A2B receptor 
 gga-u.3   ADORA2A   adenosine A2a receptor 
 gga-u.3   ADORA1   adenosine A1 receptor 
 mcc-u.3   ADORA3   adenosine A3 receptor 
 mcc-u.3   ADORA2A   adenosine A2a receptor 
 mcc-u.3   ADORA1   adenosine A1 receptor 
 cfa-u.3   ADORA2B   adenosine A2b receptor 
 cfa-u.3   ADORA2A   adenosine A2a receptor 
 cfa-u.3   ADORA1   adenosine A1 receptor 
 dme-u.3   AdoR   Adenosine receptor 
 cel-u.3   ador-1   G_PROTEIN_RECEP_F1_2 domain-containing protein 

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Top 50 coexpressed genes to adora2b (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre1040   Biosynthesis of unsaturated fatty acids  2 31 2.58
 dre62   Fatty acid elongation  2 36 2.45
 dre1212   Fatty acid metabolism  2 78 -
 dre4020   Calcium signaling pathway  3 377 -
 dre4010   MAPK signaling pathway  3 409 -

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dre:adora2b (adenosine A2b receptor) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dre-u.3
for
adora2b
dre-r.3
for
adora2b
dre-u.3
for
adora4a
hsa-u.4
for
ADORA1
mmu-u.4
for
Adora2a
mmu-u.4
for
Adora1
rno-u.3
for
Adora1
rno-u.3
for
Adora2b
gga-u.3
for
ADORA2A
gga-u.3
for
ADORA1
mcc-u.3
for
ADORA3
mcc-u.3
for
ADORA2A
mcc-u.3
for
ADORA1
cfa-u.3
for
ADORA2B
cfa-u.3
for
ADORA2A
cfa-u.3
for
ADORA1
dme-u.3
for
AdoR
cel-u.3
for
ador-1
1 btbd11b BTB (POZ) domain containing 11b 100034519 4.4 2.3
 0.9
-0.2
 1.1
-0.1
 1.6
-0.9
 0.1
-1.6
 1.5
0.6
 1.5
-0.0
 -0.3
-1.2
 2.4
0.5
 0.4
0.2
 2.5
1.5
 0.4
-0.7
 0.4
0.0
 -0.8
-1.2
 0.9
0.3
 0.4
2 plcl2 phospholipase C like 2 100334276 4.2 2.2
 -0.4
-1.4
 -0.5
-0.8
 1.9
1.0
 1.1
-0.5
 0.2
0.1
 0.1
-2.0
 1.5
1.0
 2.0
1.1
 0.4
-0.2
 0.2
-0.9
 0.4
-0.6
 -1.2
-2.1
 0.3
-0.4
 -0.9
-1.1
3.3
3 cables2b Cdk5 and Abl enzyme substrate 2b 564291 3.6 1.9
 0.5
0.3
 0.7
-0.1
 0.6
0.2
 1.9
0.6
 2.3
-0.0
 1.6
0.2
 1.9
0.8
 0.1
-0.0
 0.5
-0.7
 0.6
-0.9
 0.3
-0.4
 1.4
-0.4
 0.5
-0.1
 -0.6
-1.2
-0.6
4 adora2aa adenosine A2a receptor a 561701 3.5 1.9
 0.0
-0.2
 0.9
 1.5
0.2
 0.2
0.2
 0.6
0.0
 0.5
0.0
 1.5
0.3
 2.3
0.3
 1.6
-0.1
 1.1
-0.1
 -0.8
-0.8
 1.7
0.7
 1.7
0.6
 -0.4
-0.5

5 LOC110438003 uncharacterized LOC110438003 110438003 3.5 1.9















6 hacd4 3-hydroxyacyl-CoA dehydratase 4 561303 3.5 1.8
 -0.5
-0.8
 -0.3
-0.9
 -0.2
-1.8
 0.3
-1.3
 -0.2
-0.6
 1.3
-0.6
 0.3
-1.2
 -1.4
-1.6
 1.2
-0.7
 0.4
-0.9
 0.3
-1.3
 0.1
-0.3
 0.3
-1.4
 0.4
0.0
 -0.9
 -1.1
7 cracdlb cracd like b 571514 3.5 1.8
 0.2
-0.6
 1.2
 0.5
 2.1
 0.3
 0.1
 -0.7
 0.4
 0.1
 0.1
 1.5
 0.7
 0.8
 0.0

8 cst3 cystatin C (amyloid angiopathy and cerebral hemorrhage) 791878 3.4 1.8
 0.2
-0.2
 0.1
-0.8
 0.5
 0.6
 1.0
 -0.0
 -1.7
 0.5
 1.6
 -2.0
 0.9
 -1.3
 -2.9
 0.7

9 mmd2a monocyte to macrophage differentiation-associated 2a 558749 3.4 1.8
 0.5
-0.9
 1.3
 2.0
0.4
 4.7
1.8
 1.3
0.4
 2.5
1.0
 0.8
-1.2
 1.4
0.8
 -0.4
 -0.3
 1.0
 -0.0
 0.4
 -0.5
 -0.9
 0.9
10 slc25a35 solute carrier family 25 member 35 557185 3.4 1.8
 -0.4
-1.0
1.1
-0.0
 1.1
0.1
 1.0
0.5
 0.7
0.7
 0.4
 0.4
 -0.9
 -0.3
 0.1
 0.0
-0.8
 1.9
1.5
 1.3
-0.9
 0.6
0.3
11 fam117bb family with sequence similarity 117 member Bb 100003476 3.4 1.8















12 unm_sa911 un-named sa911 100334992 3.4 1.8
 0.4
-0.1
 -0.1
-0.2
 2.3
1.4
 1.3
0.5
 0.6
-0.1
 1.3
0.8
 1.0
0.2
 0.8
0.6
 0.0
-0.1
 2.0
0.9
 0.2
-0.3
 -0.1
-0.5
 0.9
0.3
 -0.3
-0.4
1.7
13 rp2 RP2 activator of ARL3 GTPase 406755 3.3 1.8
 -0.2
 -1.2
 -0.4
 -0.3
 -0.0
 -0.0
 1.8
 -0.9
 -1.2
 1.4
 0.5
 -0.3
 0.6
 -1.4
0.7
14 LOC100333265 proteinase-activated receptor 3-like 100333265 3.3 1.7
 -0.2
-0.9
 0.6
 0.6
 -1.1
 -0.5
 1.7
 0.7
 -0.6


1.2
 -1.4
 -0.0

15 rasgrp3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 563441 3.2 1.7
 0.1
-0.2
 -0.7
 0.3
 -0.4
 -1.1
 -0.3
 4.0
 -0.2
 0.7
 2.0
 1.1
 -0.9
 1.4
 -0.3
1.6
16 acap3a ArfGAP with coiled-coil, ankyrin repeat and PH domains 3a 322991 3.2 1.7
 1.0
0.8
 0.2
-0.6
 1.0
0.5
 0.3
0.2
 1.1
-0.4
 -0.8
-0.9
 1.2
0.1
 2.3
0.2
 0.2
-0.1
 4.2
1.0
 0.2
-0.1
 0.3
0.1
 1.0
-0.0
 -0.5
-0.5
 -0.4
 -0.8
17 napsa napsin A aspartic peptidase 336746 3.2 1.7
 0.5
-0.5
 0.7
0.6
 0.6
-0.1
 0.8
0.5
 1.7
-0.1
 1.1
0.4
 0.8
0.4
 0.5
0.4
 0.5
0.2
 1.3
0.5
 2.4
0.8
 1.4
0.9
 1.6
1.3
 0.9
0.9
 2.0
1.0
 1.3
1.2
18 camk1b calcium/calmodulin-dependent protein kinase Ib 794026 3.2 1.7
 0.7
0.1
 1.5
1.4
 1.0
0.5
 1.7
0.3
 1.8
1.2
 1.7
1.3
 1.0
-0.0
 0.9
0.6
 1.2
-0.1
 3.5
2.0
 1.6
 1.0
0.9
 1.6
1.5
 1.3
1.3
 -0.9
 3.0
19 bcl10 BCL10 immune signaling adaptor 100334750 3.2 1.7
 -1.0
 -1.2
 1.1
 -0.7
 -0.2
 1.5
 1.1
 -0.2
 -1.6
 1.2
 -1.4
 0.1
 0.4
 -0.4

20 LOC100331257 rho-related BTB domain-containing protein 2-like 100331257 3.2 1.7















21 snx27a sorting nexin 27a 566205 3.2 1.7
 -0.1
-1.0
 0.7
 -0.5
 0.1
 -0.3
 0.3
 0.3
 -0.1
 -0.3
 -0.2
 -0.1
 0.0
 -0.3
 -0.2
 0.2
 -0.5
22 smpd2a sphingomyelin phosphodiesterase 2a 567548 3.2 1.7
 0.3
-0.6
 -1.0
 -0.8
 -0.9
 -0.9
 0.3
 0.4
 0.7
 -0.2
 -0.3
 -0.1
 0.2
 0.4
 0.1
 -0.9
 0.4
23 slc16a3a solute carrier family 16 member 3a 561627 3.2 1.7
 1.6
1.2
 0.8
0.2
 1.7
0.0
 1.7
0.9
 1.6
0.8
 1.0
0.8
 1.6
1.2
 1.3
1.0
 0.8
0.1
 1.4
1.1
 0.7
0.4
 1.3
-0.3
 1.4
1.4
 1.8
0.5
 1.5
1.0
 1.0
0.3
24 rnf217 ring finger protein 217 567287 3.2 1.7
 0.4
-1.0
 -0.1
 -1.8
 1.2
 -0.1
 -0.3
 0.5
 -2.0
 -0.1
 -0.3
 0.8
 0.7

25 agtrap angiotensin II receptor-associated protein 793937 3.1 1.7
 -0.9
 0.1
 1.0
 -1.9
 1.7
 1.1
 1.1
 -1.4
 -0.7
 0.2
 1.0
 -1.4
 1.1
 0.4
 -0.6
26 prkacba protein kinase, cAMP-dependent, catalytic, beta a 393998 3.1 1.7
 0.3
-0.1
 0.9
0.5
 1.3
0.6
 0.7
-0.3
 1.2
0.3
 0.8
-0.1
 0.2
-0.3
 0.4
0.4
 2.2
0.5
 0.8
0.6
 1.3
1.0
 -1.1
-1.5
 -0.3
-0.4
 0.7
0.0
 0.8
0.3
 1.1
1.0
27 si:rp71-1g18.13 si:rp71-1g18.13 560271 3.1 1.7
 0.6
-0.1
 -0.7
 3.1
 0.2

-0.0
 -1.0
 -0.6
 0.7
 -0.6
 -0.4
 -0.4
 0.7

28 arhgap46b Rho GTPase activating protein 46b 568268 3.1 1.7
 0.2
-0.2
 0.6
 -2.2
 0.7
 1.0
 -0.2
 -0.9
-1.5
 1.0
0.6
 0.6
 -0.1
 1.1
 1.5
 0.1
 0.0
 -0.4
 -0.1
29 dicp3.1 diverse immunoglobulin domain-containing protein 3.1 100884138 3.1 1.7















30 dlgap1b discs, large (Drosophila) homolog-associated protein 1b 571372 3.1 1.7
 1.1
-0.1
 0.6
-0.5
 1.9
0.6
 3.3
1.6
 1.4
1.1
 -0.1
-0.2
 -0.1
-0.2
 1.5
1.3
 0.6
-0.1
 1.2
0.4
 1.0
0.8
 0.2
 1.2
0.0
 1.9
1.1
 -0.9
31 rilp Rab interacting lysosomal protein 100005026 3.1 1.7
 -0.3
-0.9
 -0.2
 1.2
 -0.1
 0.1
 1.1
 -1.5
 -0.4
 -0.4
 0.3
 1.5
 1.2
 0.6
 0.6
 0.7
 -0.7
32 usp46 ubiquitin specific peptidase 46 100148916 3.1 1.7
 1.4
-0.4
 0.5
-1.3
 1.4
-1.7
 0.3
-0.4
 1.6
1.3
 0.5
0.3
 -0.1
-0.6
 1.8
1.7
 0.8
-0.3
 -0.2
-1.6
 -0.7
-0.8
 0.5
-0.1
 0.1
-0.2
 0.0
-0.7
 -1.5
 -1.1
33 cd7al cd7 antigen-like 100001623 3.1 1.6















34 hnf1a HNF1 homeobox a 266961 3.0 1.6
 -1.2
 -0.2
 1.0
 -0.7
 -0.4
 0.1
 0.4
 -0.9
 -0.2
 -0.4
 0.1
 -0.1
 1.3
 0.3

35 rflna refilin A 368489 3.0 1.6
 -0.2
-0.6
 -1.2
 -1.0
 1.5
 0.3
 -1.1


-1.5
 -0.2
 0.7

36 rinl Ras and Rab interactor-like 101884339 3.0 1.6
 0.4
0.1
 1.9
0.9
 1.2
0.6
 0.7
0.7
 2.0
-0.5
 0.0
-0.3
 2.4
0.7
 -0.7
-1.2
 1.1
0.4
 2.8
1.6
 0.2
-0.2
 0.0
-0.9
 1.3
-1.0
 0.5
0.1
 -0.2
 -0.7
37 camkk1a calcium/calmodulin-dependent protein kinase kinase 1, alpha a 541526 3.0 1.6
 0.8
-0.8
 1.2
-1.4
 1.9
-0.6
 1.2
1.1
 1.0
-0.0
 0.8
0.6
 0.3
-0.7
 0.3
-0.9
 1.1
-0.3
 1.1
-0.7
 0.7
0.1
 1.5
-0.6
 0.0
-1.5
 0.1
-0.3
 -0.5
 2.8
38 mical1 microtubule associated monooxygenase, calponin and LIM domain containing 1 568573 3.0 1.6
 -0.4
 -1.5
 0.8
 -0.5
 -0.4
 -0.3
 0.4
 0.4
 0.2
 -0.1
 0.3
 -1.1
 0.8
 -0.4

39 ptgis prostaglandin I2 (prostacyclin) synthase 559148 3.0 1.6
 -1.2
 0.4
 -1.2
 -1.0
 0.1
 0.1

-1.4
 0.8
 -0.2
 1.1
 -0.6
 0.2

40 rasa3 RAS p21 protein activator 3 100318936 3.0 1.6
 0.2
-0.4
 1.2
-0.4
 0.3
0.1
 2.0
0.4
 1.8
-0.3
 1.4
0.9
 1.7
-0.1
 -0.2
-0.3
 1.5
-1.3
 2.1
1.8
 1.4
-0.9
 1.3
-1.8
 0.7
-0.1
 -0.3
-0.6
 -0.4
 1.3
41 elovl5 ELOVL fatty acid elongase 5 393425 3.0 1.6
 1.2
0.5
 0.8
0.6
 1.5
-0.1
 0.6
0.5
 1.4
1.4
 0.7
0.0
 0.7
0.4
 1.4
0.8
 0.1
-0.0
 0.8
0.5
 2.3
0.8
 1.6
1.3
 1.0
-0.4
 1.2
-0.1
 0.7
0.5
42 vwa5a von Willebrand factor A domain containing 5A 447865 3.0 1.6
 0.3
0.1
 1.4
 -0.7
-1.0
 -0.6
-1.1
 0.6
 1.0
 0.4
 0.4
 1.0
 -1.3
 -1.0
 -0.8
 -1.1
 0.3

43 rasgrp4 RAS guanyl releasing protein 4 558453 2.9 1.6
 0.1
-0.2
 -0.7
 0.3
 -0.4
 -1.1
 -0.3
 4.0
 -0.2
 0.7
 2.0
 1.1
 -0.9
 1.4
 -0.3
1.6
44 cebpa CCAAT enhancer binding protein alpha 140815 2.9 1.6
 -0.7
 0.0
 -1.0
 3.4
 1.9
 -0.1
 -0.5
 -0.0
 0.6
 -1.9
 -0.2
 0.5
 2.4
 0.5

45 ccdc120a coiled-coil domain containing 120a 799619 2.9 1.6
 -0.2
-0.3
 -1.3
 -1.1
 0.5
 1.0
 1.5
 -0.3
 -1.5
 -0.4
 0.2
 0.8
 0.2
 -0.7
 0.4

46 neurl1aa neuralized E3 ubiquitin protein ligase 1Aa 561943 2.9 1.6
 -0.1
-0.5
 1.9
1.3
 1.0
-0.1
 1.0
1.0
 0.4
-0.7
 -0.6
-0.8
 2.7
-0.2
 1.9
1.0
 1.2
-0.3
 0.9
-2.0
 0.3
-0.6
 -0.6
-0.6
 0.4
-0.3
 1.1
-0.6
 -0.0
47 lrrc15 leucine rich repeat containing 15 791200 2.9 1.6















48 slc24a3 solute carrier family 24 member 3 557196 2.9 1.6
 1.4
-0.2
 0.5
 1.0
-0.9
 2.2
2.1
 1.9
0.9
 0.8
-0.3
 3.0
0.3
 1.1
-0.1
 3.7
0.8
 -0.1
-0.2
 0.1
0.1
 0.7
-0.3
 0.7
0.0
 0.5
0.5
 0.1
-0.6
49 ablim3 actin binding LIM protein family, member 3 566821 2.9 1.5
 0.8
-0.4
 1.3
0.2
 2.8
0.4
 2.1
1.9
 2.7
2.5
 0.4
-0.9
 1.0
0.9
 5.0
1.8
 1.4
-1.0
 0.6
0.3
 0.7
-0.3
 1.2
-0.2
 1.3
0.8
 0.6
0.3
 0.5
 -0.3
50 mtss1lb MTSS I-BAR domain containing 2b 564555 2.9 1.5
 -0.3
-0.5
 0.6
-0.1
 0.5
-1.4
 0.2
-0.7
 -0.7
-0.9
 0.5
-0.8
 -0.3
-0.4
 2.2
-0.6
 0.4
0.1
 1.0
-1.6
 0.7
0.1
 -1.0
-2.0
 0.4
-2.0
 1.1
0.6
 1.7
 -0.9
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