Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3   mlx   MAX dimerization protein MLX 
 dre-r.3   mlx   MAX dimerization protein MLX 
 hsa-u.4   MLX   MAX dimerization protein MLX 
 mmu-u.4   Mlx   MAX-like protein X 
 rno-u.3   Mlx   MAX dimerization protein MLX 
 gga-u.3   MLX   MLX, MAX dimerization protein 
 mcc-u.3   MLX   MAX dimerization protein MLX 
 cfa-u.3   MLX   MAX dimerization protein MLX 
 dme-u.3   bigmax   bigmax 
 cel-u.3   mxl-2   BHLH domain-containing protein 

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Top 50 coexpressed genes to mlx (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre4144   Endocytosis  5 324 2.93
 dre4130   SNARE interactions in vesicular transport  2 40 2.36
 dre4217   Necroptosis  2 196 -
 dre4140   Autophagy - animal  2 200 -
 dre5132   Salmonella infection  3 332 -

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dre:mlx (MAX dimerization protein MLX) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dre-u.3
for
mlx
dre-r.3
for
mlx
hsa-u.4
for
MLX
mmu-u.4
for
Mlx
rno-u.3
for
Mlx
gga-u.3
for
MLX
mcc-u.3
for
MLX
cfa-u.3
for
MLX
dme-u.3
for
bigmax
cel-u.3
for
mxl-2
1 rnaseka ribonuclease, RNase K a 751692 6.4 3.3
2.7
 2.6
 0.4
 1.8
 1.5
 0.8
 0.6
0.2
2 mob1a MOB kinase activator 1A 100005014 6.2 3.3
 3.3
1.1
 1.7
1.1
 0.8
0.8
 1.1
0.7
 1.0
0.9
 1.0
0.7
 0.4
-0.3
 2.7
2.0
3 si:dkey-16l2.16 si:dkey-16l2.16 100003902 5.8 3.0
2.5
 0.3
 2.7
 1.1
 0.0
 0.9
 1.1
4 mtmr14 myotubularin related protein 14 323929 5.7 3.0
 2.2
 0.9
 1.7
 2.2
 1.8
 0.7
 2.2
5 cemip2 cell migration inducing hyaluronidase 2 566851 5.5 2.9
 -0.5
 1.2
 -0.1
 -1.4
 -0.7
 -0.5

6 trnau1apa tRNA selenocysteine 1 associated protein 1a 553636 5.4 2.8
 2.3
 0.8
 -0.1
 4.1
0.3
 0.9
 1.7
 2.4
 -0.7
7 stx4 syntaxin 4 323735 5.2 2.7
 0.9
0.8
 1.4
1.3
 2.0
0.2
 0.1
0.0
 3.1
2.7
 2.5
0.2
 0.3
 1.9
-0.7
8 st3gal3a ST3 beta-galactoside alpha-2,3-sialyltransferase 3a 393326 5.2 2.7
1.8
 0.6
 0.4
 0.4
 0.6

9 fuca1.2 alpha-L-fucosidase 1, tandem duplicate 2 445165 5.0 2.6
 0.4
-0.4
 1.4
0.2
 1.4
-0.8
 -0.0
-0.7
 1.7
1.2
 0.2
-0.3
-1.2
10 tmem110l transmembrane protein 110, like 393166 4.8 2.5
 1.1
 0.9
1.5
0.9
 0.9
 0.5

11 pbx2 pre-B-cell leukemia homeobox 2 58136 4.8 2.5
 1.6
1.2
 0.5
-0.2
 1.5
0.0
 0.4
-0.0
 0.4
0.4
 0.7
0.6
 -0.6
 0.6
0.0
12 snx1a sorting nexin 1a 337386 4.7 2.5
 2.0
0.7
 1.4
0.7
 2.3
1.5
 1.2
0.3
 2.9
1.2
 1.3
-1.4
 0.2
 1.0
13 pa2g4b proliferation-associated 2G4, b 323462 4.6 2.4
 0.8
 -0.9
 0.5
 1.5
 0.8
 1.1
 0.7
 0.2
14 eif5a2 eukaryotic translation initiation factor 5A2 406546 4.6 2.4
 0.8
0.1
 2.4
-2.1
 2.7
-0.4
 2.0
0.2
 1.1
-0.8
 1.2
0.6
 1.4
 1.1
-1.4
15 ppardb peroxisome proliferator-activated receptor delta b 30754 4.5 2.4
 2.1
 1.5
 1.0
 -0.1
 0.1
 0.1

16 si:ch211-218c6.8 si:ch211-218c6.8 100001903 4.5 2.4
-0.7
 -0.3
 0.3
 -1.0
 -0.6

17 zfand6 zinc finger, AN1-type domain 6 336461 4.5 2.4
 0.1
-0.4
 -0.6
-1.1
 0.6
-0.1
 0.2
-0.3
 1.7
1.2
 1.2
-1.3
4.7
18 bri3 brain protein I3 100002236 4.5 2.4
 1.4

0.6
 1.9
 1.9
 3.2
19 tradd tnfrsf1a-associated via death domain 58130 4.5 2.4
 0.5
 2.8
 0.6
 -1.1
 0.6
 2.5

20 tspan14 tetraspanin 14 751700 4.5 2.4
 1.7
-1.4
 0.8
0.3
 0.4
-0.5
 -0.1
-0.5
 1.2
0.6
 0.5
0.1
 -0.6
 1.7
21 arf1 ADP-ribosylation factor 1 114428 4.5 2.4
 1.0
0.8
 4.5
1.7
 5.8
4.3
 3.0
0.7
 3.6
1.7
 3.8
0.5
 -1.0
-1.1
 0.7
-1.4
22 nenf neudesin neurotrophic factor 571299 4.4 2.3
 -0.9
 -2.5
 -0.8
 1.2
 0.3
 0.7

23 lman2lb lectin, mannose-binding 2-like b 767766 4.4 2.3
 1.6
0.4
 2.4
0.5
 2.1
1.7
 0.4
0.3
 2.4
1.7
 2.5
2.2
 -1.6
 -1.8
24 pkn2a protein kinase N2a 571965 4.4 2.3
 0.1
-0.4
 0.5
0.4
 0.0
-0.5
 0.1
-0.4
 0.8
-1.2
 0.2
-0.5
 0.5
 -0.2
25 rhebl1 Ras homolog, mTORC1 binding like 1 767781 4.3 2.3
 -1.0
-1.3
 0.2
-0.6
 3.7
 2.1
 0.7
 1.2
-0.0
 7.2
 0.7
26 ercc1 excision repair cross-complementation group 1 100001425 4.3 2.3
 1.6
 0.1
 0.5
2.6
 1.1
 -1.4
 3.3
27 bin3 bridging integrator 3 323976 4.3 2.3
 1.7
 0.6
 1.5
 0.6
 1.6
 -0.3

28 atf1 activating transcription factor 1 325609 4.3 2.3
 3.3
2.0
 0.4
-1.4
 1.4
1.0
 3.9
-0.6
 1.1
0.7
 0.4
0.2
 1.5
 2.1
29 ormdl1 ORMDL sphingolipid biosynthesis regulator 1 368632 4.3 2.3
 4.1
1.3
 3.8
1.9
 3.0
1.3
 1.4
0.9
 3.4
1.8
 3.6
-0.7
 3.8
30 stk17b serine/threonine kinase 17b (apoptosis-inducing) 393507 4.3 2.2
 0.3
-0.4
 0.1
 0.5
 0.5
-1.4
 0.8
-1.3
 -0.1
-0.6
 2.4
31 pef1 penta-EF-hand domain containing 1 445249 4.2 2.2
 1.5
0.4
 2.7
2.6
 3.9
3.4
 4.1
1.1
 2.6
2.0
 1.5
1.5
 1.9
0.2
 1.8
32 si:dkey-6n21.12 si:dkey-6n21.12 100003436 4.2 2.2







33 csde1 cold shock domain containing E1, RNA-binding 336679 4.2 2.2
 -1.1
 -1.2
 -0.1
 1.3
 1.1
 0.2
 -2.7
34 tspan7 tetraspanin 7 406802 4.2 2.2
 -0.1

-0.1
 -0.6

-0.1
35 dcp2 decapping mRNA 2 393121 4.1 2.2
 -0.4
 -1.2
 -0.8
 1.6
 0.9
 0.6
 0.1
 3.3
36 arpc5b actin related protein 2/3 complex, subunit 5B 399482 4.1 2.2
 1.5
0.8
 2.3
0.2
 3.6
3.0
 2.9
0.6
 3.2
-0.7
 1.9
1.2
 1.1
 5.2
37 cldn12 claudin 12 81593 4.1 2.2
 1.4
 0.8
 1.2
 1.2
 -0.4
 0.4

38 reep3b receptor accessory protein 3b 393130 4.1 2.2
 0.1
0.0
 1.7
-0.1
 1.4
-0.0
 0.2
-0.1
 0.2
0.1
 1.0
-0.6
 -0.4
 1.3
39 alpk1 alpha-kinase 1 100333928 4.1 2.1
 0.3
 0.7
 -0.9
 0.2
 1.0
 -1.9

40 chmp5b charged multivesicular body protein 5b 393351 4.0 2.1
 1.4
 3.5
 2.0
 1.8
 2.4
 1.7
 3.3
 1.7
41 adam8a ADAM metallopeptidase domain 8a 368917 4.0 2.1
 0.1
-0.0
 1.0
0.2
 1.2
-0.0
 0.7
0.6
 1.6
-0.3
 -0.2
-0.4
 -0.2
-1.1
 1.7
1.4
42 tmem134 transmembrane protein 134 393340 4.0 2.1
 -1.1
 -0.2
 -1.0
0.4
 1.2
 1.1
 3.1
43 sav1 salvador family WW domain containing protein 1 447821 4.0 2.1
 -1.7
 -0.2
 -1.2
 2.6
 -0.4
 -0.5
 0.7
 1.7
44 cdyl chromodomain protein, Y-like 568457 4.0 2.1
 -0.3
 0.1
 -1.0
 -0.6
 -1.7
 0.5

45 vamp3 vesicle-associated membrane protein 3 (cellubrevin) 415163 4.0 2.1
 1.8
1.7
 1.6
0.7
 1.3
1.0
 0.1
-0.0
 1.0
0.5
 1.2
0.6
 1.1
0.5
 3.7
2.9
46 pdap1a pdgfa associated protein 1a 322973 3.9 2.1
 0.1
 0.0
 1.5
 0.5
 0.9
 1.6
 0.2
0.0
47 ptp4a3b protein tyrosine phosphatase 4A3b 567691 3.9 2.1
 0.9
0.2
 0.1
-1.6
 -0.1
-0.6
 3.0
0.5
 0.3
-0.6
 -0.2
-0.4
0.7
48 ldlrad3 low density lipoprotein receptor class A domain containing 3 570705 3.9 2.1
 0.1
 0.2
 -2.3
 -1.9
 0.3
 -0.5
 -0.3
-0.4
49 zgc:123010 zgc:123010 641500 3.9 2.1
 1.0

0.6
 2.2
 0.5

50 pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 406470 3.8 2.0
 2.0
-0.9
 2.1
-0.1
 0.8
0.1
 1.7
0.6
 0.8
0.1
 1.3
-0.0
0.2
-0.5
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