Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3   srd5a2a   steroid-5-alpha-reductase, alpha polypeptide 2a 
 dre-r.3   srd5a2a   steroid-5-alpha-reductase, alpha polypeptide 2a 
 dre-m.5   srd5a2a   steroid-5-alpha-reductase, alpha polypeptide 2a 
 hsa-u.4   SRD5A1   steroid 5 alpha-reductase 1 
 hsa-u.4   SRD5A2   steroid 5 alpha-reductase 2 
 mmu-u.4   Srd5a2   steroid 5 alpha-reductase 2 
 mmu-u.4   Srd5a1   steroid 5 alpha-reductase 1 
 rno-u.3   Srd5a1   steroid 5 alpha-reductase 1 
 gga-u.3   SRD5A1   steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 
 gga-u.3   SRD5A2   steroid 5 alpha-reductase 2 
 mcc-u.3   SRD5A1   steroid 5 alpha-reductase 1 
 cfa-u.3   SRD5A1   steroid 5 alpha-reductase 1 
 cel-u.3   ZK1251.3   3-oxo-5-alpha-steroid 4-dehydrogenase 
 cel-u.3   F42F12.3   3-oxo-5-alpha-steroid 4-dehydrogenase 
 cel-u.3   F19H6.4   3-oxo-5-alpha-steroid 4-dehydrogenase 
 spo-u.3   SPCC126.08c   putative lectin family glycoprotein receptor 

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Top 50 coexpressed genes to srd5a2a (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre120   Primary bile acid biosynthesis  5 22 6.64
 dre3320   PPAR signaling pathway  5 84 5.71
 dre230   Purine metabolism  4 156 3.23
 dre920   Sulfur metabolism  2 10 3.58
 dre240   Pyrimidine metabolism  2 74 -

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dre:srd5a2a (steroid-5-alpha-reductase, alpha polypeptide 2a) External Links;


Show/Hide Columns:        
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dre-u.3
for
srd5a2a
dre-r.3
for
srd5a2a
dre-m.5
for
srd5a2a
hsa-u.4
for
SRD5A1
hsa-u.4
for
SRD5A2
mmu-u.4
for
Srd5a2
mmu-u.4
for
Srd5a1
rno-u.3
for
Srd5a1
gga-u.3
for
SRD5A1
gga-u.3
for
SRD5A2
mcc-u.3
for
SRD5A1
cfa-u.3
for
SRD5A1
cel-u.3
for
ZK1251.3
cel-u.3
for
F42F12.3
cel-u.3
for
F19H6.4
spo-u.3
for
SPCC126.08c
1 papss2a 3'-phosphoadenosine 5'-phosphosulfate synthase 2a 777719 6.0 3.1
2.0
1.1
 -0.6
-0.7
 1.7
-0.9
 1.7
-0.6
 2.1
1.0
 0.9
-0.0
 -0.2
-0.3
 1.0
0.0
 1.7
0.8
 -0.8
 -1.4
 -1.0
 -0.6
2 si:dkey-91i10.3 si:dkey-91i10.3 565876 5.8 3.1
1.1
0.7
 1.2
0.5
 0.2
 1.5
 1.9
 0.9
0.4
 -0.4
-0.5
 -0.6
-1.0
 0.5
-0.0


0.5
0.3
3 gcshb glycine cleavage system protein H (aminomethyl carrier), b 436852 5.6 2.8
 2.4
 2.9
 0.3
 1.1
 1.2
 1.4
 -0.6
 -1.0
 1.3
 1.2
 1.4
-0.4
 1.5
0.0
 -0.3
-1.1
4 si:ch211-107o10.3 si:ch211-107o10.3 407663 5.5 2.7
 2.4
 1.5
0.7
 0.5
0.5
 1.0
0.0
 2.7
2.0
 3.0
0.5
 0.8
0.5
 1.8
-0.3
 2.5
0.9
 1.6
1.2
 -0.6
-1.1
 1.2
0.7
 1.1
0.2
5 entpd8 ectonucleoside triphosphate diphosphohydrolase 8 436652 5.5 2.9
-0.9
 1.1
 4.3
 1.1
 0.6
 -0.4
-0.4
 1.2
0.4
 0.2




6 cyp7a1 cytochrome P450, family 7, subfamily A, polypeptide 1 394148 5.5 2.9


1.8
 0.3
 0.3
 -0.0
 -0.3





7 cyp8b3 cytochrome P450, family 8, subfamily B, polypeptide 3 447848 5.4 2.3
 2.7
 -0.0
 4.1
 0.7
 1.4
 -0.1

-0.7
 -1.2



8 nt5e 5'-nucleotidase, ecto (CD73) 393906 5.1 1.4
 3.3
 0.3
 0.1
 1.5
 -0.8
 0.6
 0.5
 0.7
 0.6
 -0.6


-0.1
9 dhrs9 dehydrogenase/reductase (SDR family) member 9 322529 5.0 2.8
 1.8
 1.6
0.6
 2.7
1.7
 5.2
3.6
 2.6
1.3
 3.5
2.8
 1.6
0.9
 2.5
1.0
 1.4
0.7
 2.1
1.0
 1.2
0.3
 1.9
1.7
 -0.5
-0.7
 -1.0
-1.1
10 cyp8b1 cytochrome P450, family 8, subfamily B, polypeptide 1 445281 4.9 2.0
 2.5
 -0.0
 4.1
 0.7
 1.4
 -0.1

-0.7
 -1.2



11 vil1 villin 1 393207 4.8 2.6
 1.9
 -0.6
 -0.6
 1.5
 -0.0
 -0.4
 -0.8
 -0.8
 -0.1
 0.1



12 serpinb1l4 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4 335229 4.6 2.4
0.7
0.6
 3.9
1.8
 1.3
0.8
 1.2
1.1
 0.4
0.2
 0.7
0.6
 1.7
0.7
 0.6
0.3
 0.7
0.2
 -0.1
-0.2
 2.5
1.2
 0.6
0.6
13 slc51a solute carrier family 51 subunit alpha 447807 4.5 2.4
1.2
 1.5
 0.9
 -1.1
 0.2
 0.5
-0.7
 1.7
-1.1
 0.2




14 hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 327462 4.3 1.7
 2.3
 1.4
0.5
 0.4
-0.2
 3.5
2.8
 4.1
2.2
 0.2
0.2
 0.9
-0.1
 -0.7
-1.3
 1.1
0.1
 0.4
-0.1
 0.8
 0.7
 -0.9
 0.7
-0.4
15 porb P450 (cytochrome) oxidoreductase b 327556 4.3 2.3
0.8
 0.5
 -0.4
 -0.5
 1.2
 0.9
 -1.6
 0.5
 0.1
 -0.9
 0.5
 -1.1
 1.4
16 upk1a uroplakin 1a 678515 4.2 1.7
 2.2

0.9
 -0.6
 -0.0


-0.5



17 bpnt1 bisphosphate nucleotidase 1 436627 4.2 1.8
 2.0
 -0.4
 -0.8
 0.8
 2.3
 0.8
 0.8
 -0.5
 0.4
 1.3
 0.8
 0.4
 0.0
18 LOC100151490 cdc42 effector protein 3-like 100151490 4.2 2.2













19 zgc:194948 zgc:194948 796981 4.1 2.2
-0.2
 -0.4

-0.6


-0.7



20 LOC565594 uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 565594 4.0 2.0
 1.8












21 fut9b.4 fucosyltransferase 9b, tandem duplicate 4 664694 4.0 1.7
 2.0
 0.9
0.7
 1.2
1.2
 0.7
0.5
 0.9
-0.1
 1.0
0.4
 0.6
0.3
 1.0
0.3
 2.1
1.4
 0.6
-0.7
 0.4
-0.2
 0.9
-0.3
 1.6
-0.4
22 mep1a.1 meprin A, alpha (PABA peptide hydrolase), tandem duplicate 1 553530 4.0 1.3
 2.4
 0.8
-0.9
 2.4
1.1
 3.2
3.1
 0.1
-0.8
 -0.7
-0.8
 0.4
0.0
 0.5
-0.4
 0.4
-1.2




23 fxyd5 FXYD domain containing ion transport regulator 5 567610 3.9 2.1













24 msmo1 methylsterol monooxygenase 1 406662 3.9 2.1
 1.5
 1.9
 0.9
 0.6
 2.9
 3.5
 1.5
 -1.3
 1.3
 1.0
0.7



25 tmprss13b transmembrane serine protease 13b 564693 3.8 1.8
 1.8
 -0.2
 -0.3

0.2
 1.3
 1.0
 1.9
 -0.9



26 slc38a4 solute carrier family 38 member 4 449771 3.8 1.6
 2.0
 1.0
0.7
 1.3
0.3
 1.2
0.3
 1.2
0.5
 1.7
0.4
 1.3
1.2
 0.6
0.4
 1.0
0.7
 1.1



27 zgc:92161 zgc:92161 447817 3.8 1.7
 1.9




1.0
0.5
 1.0
0.5

1.6
1.4
 4.2
1.9
 0.5
0.2
28 slco2a1 solute carrier organic anion transporter family, member 2A1 100038802 3.8 2.0













29 cyb5r2 cytochrome b5 reductase 2 751641 3.8 2.0
1.3
0.2
 0.3
-0.3
 0.1
-0.4
 0.9
-1.5
 2.6
-1.1
 1.9
-0.2
 0.1
-0.2
 -0.0
-0.2
 0.3
-0.0
 -1.4
 1.9
 -0.4
 0.5
30 dio1 iodothyronine deiodinase 1 799937 3.7 2.0
 1.4
 -0.5
 4.4
 1.3
 0.8
 0.3
 -0.5
 -0.8
 0.1
 -0.7



31 dsc2l desmocollin 2 like 560091 3.6 1.4
 2.0
 -0.0
-0.4
 0.4
-0.6
 1.2
1.0
 0.9
0.7
 0.8
-0.4
 0.4
 -0.1
 0.8
0.2
 1.0
-0.2


0.3
32 fkbp5 FKBP prolyl isomerase 5 368924 3.6 1.6
 1.7
 0.6
 -0.8
 0.8
 -0.6
 -0.9
 -0.3
 -0.6
 0.0
 -0.5



33 sult1st6 sulfotransferase family 1, cytosolic sulfotransferase 6 436872 3.6 1.9
0.8
0.5
 1.8
1.3
 4.4
3.4
 2.5
2.2
 3.9
2.9
 0.7
0.4
 0.6
0.2
 1.8
0.9
 1.1
0.9
 -1.5
 -0.4
 -0.4
34 gda guanine deaminase 553701 3.6 1.1
 2.2
 0.1
 1.6
 0.2
 0.3
 -0.7
 0.7
 0.0
 0.2
 0.0
 0.2
 3.5
 -0.1
 1.9
35 cpo carboxypeptidase O 100005630 3.5 1.9
0.7
0.6
 1.2
1.0
 0.5
0.0
 1.1
0.7
 2.9
1.2
 0.7
0.5
 0.6
0.4
 0.9
-1.0
 0.3
-0.2
 0.9
0.6
 1.1
-0.1
 0.0
-0.1
36 aqp8a.2 aquaporin 8a, tandem duplicate 2 563130 3.5 1.9
-1.3
 1.1
 2.1
 0.2
 -0.9
 -0.2
 -0.5
-0.5
 0.6
-0.7
 0.4
-0.4
 0.8
0.3
37 grtp1a growth hormone regulated TBC protein 1a 406711 3.5 1.7
 1.5
 0.9
 0.6
 0.8
 1.2
 -0.2
 0.1
 0.5
 0.8
 -0.1
 -1.1
 -0.1
 -0.6
38 si:ch211-201h21.5 si:ch211-201h21.5 555526 3.4 1.8









-0.4
-0.6
 1.9
0.1
 0.1
-0.9
39 si:dkey-242g16.2 si:dkey-242g16.2 336380 3.4 1.8
0.8
-0.6
 0.4
0.1
 0.0
-0.4
 0.9
 2.0
2.0
 0.6
0.6
 2.2
0.1
 -0.7
-1.2
 -0.5
-0.9
 -0.9
 1.1
 -0.2
40 zgc:136870 zgc:136870 664693 3.4 1.8













41 shbg sex hormone-binding globulin 322604 3.4 1.2
 2.0



-0.3

0.0




42 mttp microsomal triglyceride transfer protein 406207 3.4 1.4
 1.8
 1.2
 3.2
 -0.2
 0.9
 1.9
 0.9
-0.2
 -1.6
-2.1
 0.1
 -1.4



43 cyp2n13 cytochrome P450, family 2, subfamily N, polypeptide 13 492484 3.4 1.8
0.2
 2.1
 3.8
3.3
 3.1
1.5
 2.0
0.6
 2.2
1.9
 0.2
-0.1
 1.5
 1.7
 0.1
-0.1
 2.0
1.8
 0.4
-0.1
 2.9
44 tdo2a tryptophan 2,3-dioxygenase a 100008541 3.4 1.6
 1.5
 0.2
 1.6
 0.4
 2.0
 -0.1
 0.6
 -0.3
 0.3
-0.1
 1.2
 -0.2
45 faah2b fatty acid amide hydrolase 2b 768298 3.4 1.3
 1.9
 0.3
 0.7


0.1
 -0.7
 1.9
-0.8
 0.6
 0.3
46 slc27a2b solute carrier family 27 member 2b 100004228 3.4 1.8
1.5
1.2
 1.7
0.6
 1.0
-0.3
 1.6
1.2
 1.9
1.6
 1.6
1.2
 1.5
0.9
 1.8
1.0
 1.3
-0.3
 0.7
-1.1
 3.0
-0.1
 -0.2
-1.0
 0.1
47 dsg2.1 desmoglein 2, tandem duplicate 1 560026 3.4 1.1
 2.0
 1.4
0.4
 2.1
-0.5
 0.8
0.8
 1.0
0.8
 0.9
0.4
 0.6
0.3
 1.7
-0.3
 1.2
-0.0
 0.4
0.2


1.5
48 krt1-19d keratin, type 1, gene 19d 664718 3.3 1.3
 1.9












49 tm4sf4 transmembrane 4 L six family member 4 445095 3.3 1.2
 1.9
 0.3
 1.2
 2.8
 0.3
 0.6
 -0.5
 -1.2
 0.3




50 rgs13 regulator of G protein signaling 13 100037359 3.3 1.4
 1.7












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