Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3   tmco4   transmembrane and coiled-coil domains 4 
 dre-r.3   tmco4   transmembrane and coiled-coil domains 4 
 hsa-u.4   TMCO4   transmembrane and coiled-coil domains 4 
 mmu-u.4   Tmco4   transmembrane and coiled-coil domains 4 
 rno-u.3   Tmco4   transmembrane and coiled-coil domains 4 
 gga-u.3   TMCO4   transmembrane and coiled-coil domains 4 
 mcc-u.3   TMCO4   transmembrane and coiled-coil domains 4 
 cfa-u.3   TMCO4   transmembrane and coiled-coil domains 4 
 cel-u.3   F35D11.3   putative membrane protein F35D11.3 
 sce-u.3   MIL1   Mil1p 
 spo-u.3   rev1   putative deoxycytidyl transferase Rev1 

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Top 50 coexpressed genes to tmco4 (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre4010   MAPK signaling pathway  7 369 4.51
 dre5132   Salmonella infection  6 306 4.00
 dre5168   Herpes simplex virus 1 infection  4 173 3.07
 dre4620   Toll-like receptor signaling pathway  3 78 3.03
 dre4510   Focal adhesion  3 278 -

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dre:tmco4 (transmembrane and coiled-coil domains 4) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dre-u.3
for
tmco4
dre-r.3
for
tmco4
hsa-u.4
for
TMCO4
mmu-u.4
for
Tmco4
rno-u.3
for
Tmco4
gga-u.3
for
TMCO4
mcc-u.3
for
TMCO4
cfa-u.3
for
TMCO4
cel-u.3
for
F35D11.3
sce-u.3
for
MIL1
spo-u.3
for
rev1
1 xkr8.3 XK, Kell blood group complex subunit-related family, member 8, tandem duplicate 3 497082 5.0 2.6
 2.5
 0.5
 -0.1
 0.3
 1.4
 2.7


2 cep63 centrosomal protein 63 393574 4.9 2.6
 1.0
 0.7
 1.2
 1.3
 -0.1
 -2.4


3 pskh1 protein serine kinase H1 554840 4.6 2.4
 1.2
 3.6
1.1
 1.3
 2.3
 0.5
-0.9
4 tmco6 transmembrane and coiled-coil domains 6 559069 4.5 2.4
 0.7
 0.7
 1.5
 -1.2
 -0.3
 2.5


5 hps5 HPS5 biogenesis of lysosomal organelles complex 2 subunit 2 100037388 4.3 2.3
 -0.3
 0.4
 1.3
 -0.4
 1.8
 0.8
 0.5

6 cdk5rap3 CDK5 regulatory subunit associated protein 3 415195 3.9 2.1
 1.1
 0.5
 0.9
 1.8
 1.5
 0.1
 -0.4

7 dnm2b dynamin 2b 406525 3.9 2.1
 0.6
-0.9
 1.9
-0.5
 1.3
-2.1
 1.3
-0.2
 1.3
-0.5
 3.5
-0.4
 0.2
-0.4
8 golph3b golgi phosphoprotein 3b 561662 3.9 2.1
 0.7
-0.0
 1.0
0.3
 0.6
0.1
 1.0
0.1
 -0.0
-0.1
 -0.8
-1.2
 0.4
 0.5
9 akt2l v-akt murine thymoma viral oncogene homolog 2, like 403146 3.9 2.1
 1.8
1.6
 2.5
1.1
 1.5
1.3
 -0.1
-0.4
 1.7
0.5
 1.4
-0.9
 2.9
1.6

10 pcsk5b proprotein convertase subtilisin/kexin type 5b 559556 3.7 2.0
 3.3
0.6
 2.4
0.9
 1.6
0.4
 1.6
0.8
 1.6
1.4
 1.4
0.9
 2.0
1.5
 1.0
 -0.1
11 arhgef28a Rho guanine nucleotide exchange factor (GEF) 28a 559941 3.7 2.0
 1.5
 0.2
 1.2
 0.2
 -0.8
 -0.4


12 st3gal3b ST3 beta-galactoside alpha-2,3-sialyltransferase 3b 407659 3.6 1.9
1.7
 0.6
 0.4
 0.5
 0.1


13 trim32 tripartite motif containing 32 562764 3.6 1.9
 -0.5
 -0.3
 -1.3
 0.7
 -0.2
 0.3
 1.0
0.9

14 arl4aa ADP-ribosylation factor-like 4aa 393834 3.6 1.9
 -0.1
-0.1
 0.3
-0.9
 0.2
0.2
 -0.4
-1.2
 0.5
-1.2
 0.6
-0.7


15 marc1 mitochondrial amidoxime reducing component 1 378742 3.6 1.9
 1.8
0.8
 1.0
0.2
 1.2
0.1
 0.3
 0.9
0.0
 -0.8
-1.1
 1.7
1.4
-0.9
16 tab2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 494163 3.4 1.8
0.4
 0.8
 -0.2
 -1.7
 -1.0


17 snx10a sorting nexin 10a 403027 3.4 1.8
 -1.0
 0.9
 0.9
 -1.0
 -0.1
 0.3


18 pdgfab platelet-derived growth factor alpha polypeptide b 767790 3.4 1.8
 -0.1
-0.3
 -0.6
-1.3
 0.8
-0.1
 -1.3
-1.8
 0.6
0.1
 0.4
-0.6


19 txnrd2.2 thioredoxin reductase 2, tandem duplicate 2 798259 3.4 1.8
 3.2
0.0
 1.9
0.8
 1.8
1.3
 1.4
1.2
 2.3
0.1
 1.5
-0.3
 1.3
1.0

20 ehhadh enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 100000859 3.4 1.8
 1.9
 2.0
 0.1
 1.4
 2.5
 1.0


21 rab12 RAB12, member RAS oncogene family 553657 3.3 1.8
 -0.1
 -0.3
 -1.2
 -2.1
 -1.3
 0.8


22 irak4 interleukin-1 receptor-associated kinase 4 393132 3.3 1.8
 2.0
 3.1
 0.7
 3.0
 0.6
 0.7
 0.0

23 pkn2a protein kinase N2a 571965 3.3 1.8
 1.8
1.8
 1.4
0.8
 2.5
0.5
 0.1
-0.3
 0.5
0.2
 1.7
-0.2
 1.2
-0.5
24 dipk2aa divergent protein kinase domain 2Aa 492795 3.3 1.8
 -0.9
 -0.6
 -1.1
 0.1
-0.8
 -0.1
-1.5
 0.3
0.3


25 rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase 405832 3.3 1.8
 0.5
-0.3
 0.9
-0.6
 0.6
0.5
 -0.3
-0.5
 0.9
-0.5
 1.3
-0.7


26 rab13 RAB13, member RAS oncogene family 373105 3.3 1.8
 1.0
0.5
 1.5
0.8
 0.5
0.2
 -0.2
-0.5
 0.3
-0.1
 0.6
0.3
 0.1
-0.2
 1.0
27 invs inversin 245946 3.3 1.8
 -0.0
 -0.3
 0.6
 1.3
 2.6
 -0.1
 -1.4

28 zgc:77158 zgc:77158 402971 3.3 1.7
 -0.3
 -0.5
 1.0
 2.1
 0.1
 -0.4


29 igsf9b immunoglobulin superfamily, member 9b 553348 3.3 1.7
 -0.3
-1.1
 -0.6
 -0.5
 0.9
-1.3
 -0.9
-1.2
 1.4
 -1.0
-0.5
30 tradd tnfrsf1a-associated via death domain 58130 3.2 1.7
 2.4
 1.3
 1.4
 3.5
 0.5
 1.2


31 furina furin (paired basic amino acid cleaving enzyme) a 566557 3.2 1.7
 3.3
0.6
 2.4
0.9
 1.6
0.4
 1.6
0.8
 1.6
1.4
 1.4
0.9
 2.0
1.5
 1.0
 -0.1
32 upf3b UPF3B regulator of nonsense mediated mRNA decay 393929 3.2 1.7
 0.1
 0.7
-1.6
 -0.1
-1.3
 -0.7
 -1.1
-1.2
 0.1
-0.3
 -1.1

33 ppox protoporphyrinogen oxidase 664750 3.2 1.7
 0.9
 -0.3
 1.0
 -0.0
 1.9
 1.1
-0.1
34 armt1 acidic residue methyltransferase 1 541518 3.2 1.7
 -1.3
 -0.4
 -1.0
 0.5
 -0.2
 0.1
 0.6
 0.2
 -0.9
35 stx17 syntaxin 17 492808 3.2 1.7
 1.4
 0.4
 0.8
 1.3
 0.5
 -2.1


36 pgghg protein-glucosylgalactosylhydroxylysine glucosidase 777617 3.2 1.7
 1.4
 1.7
 3.0
 1.0
 0.2
 1.9
1.0
37 itga9 integrin, alpha 9 394012 3.2 1.7
 -0.7
 -0.3
 0.9
 -1.2
 0.5
 -1.1


38 znf277 zinc finger protein 277 393402 3.2 1.7
 -0.8
 0.4
 1.5
 -0.4
 -1.5
 0.3
 1.2

39 rasa1b RAS p21 protein activator (GTPase activating protein) 1b 564822 3.2 1.7
 0.1
 -0.0
 -1.5
 0.1
-2.3
 -0.5
 0.1


40 foxj2 forkhead box J2 558490 3.2 1.7
 0.8
0.3
 1.4
0.8
 1.2
0.5
 1.1
0.0
 1.4
0.1
 1.8
1.0
 2.2
1.4
 1.2
0.3
41 rint1 RAD50 interactor 1 562894 3.2 1.7
 -1.4
 0.2
 -2.1
 0.6
 -2.0
 -0.5


42 snx9b sorting nexin 9b 558917 3.1 1.7
 -0.0
 1.6
 1.7
 0.0
 -0.4
 -0.7


43 fhip2b FHF complex subunit HOOK interacting protein 2B 777718 3.1 1.7








44 bnip2 BCL2 interacting protein 2 394197 3.1 1.7
 -1.0
-1.2
 -0.2
-0.4
 -0.5
-1.3
 -0.3
-2.3
 -0.4
-1.0
 1.1
-1.5


45 insig2 insulin induced gene 2 399645 3.1 1.7
 -1.0
-1.8
 -0.2
-1.9
 0.2
-0.9
 0.3
-0.3
 -1.1
-1.9
 0.7


46 arih1l ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like 405859 3.1 1.7
 -0.8
 -0.4
 -0.4
 -1.1
 -0.7
 -1.1
 1.6
0.8
 2.0
47 spata13 spermatogenesis associated 13 568426 3.1 1.6
 -0.2
 0.8
-0.2
 0.5
-0.2
 1.3
0.1
 1.2
0.2
 2.0
0.9
1.3
48 surf4 surfeit 4 394102 3.1 1.6
 0.3
 0.7
 -0.1
 1.0
 0.2
 -0.7
 -0.8
-0.9
 -0.9
 0.3
49 rps6ka4 ribosomal protein S6 kinase, polypeptide 4 561959 3.1 1.6
 1.8
1.2
 1.9
-0.4
 1.3
1.3
 -1.5
 0.7
-0.2
 2.9
-0.7
 2.5

50 pnpt1 polyribonucleotide nucleotidyltransferase 1 100750260 3.1 1.6








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