Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3  usp4  ubiquitin specific peptidase 4 (proto-oncogene) 
 dre-r.3  usp4  ubiquitin specific peptidase 4 (proto-oncogene) 
 dre-u.3  usp15  ubiquitin specific peptidase 15 
 dre-u.3  usp11  ubiquitin specific peptidase 11 
 hsa-u.4  USP15  ubiquitin specific peptidase 15 
 hsa-u.4  USP4  ubiquitin specific peptidase 4 
 hsa-u.4  USP11  ubiquitin specific peptidase 11 
 mmu-u.4  Usp4  ubiquitin specific peptidase 4 (proto-oncogene) 
 mmu-u.4  Usp11  ubiquitin specific peptidase 11 
 rno-u.3  Usp4  ubiquitin specific peptidase 4 
 rno-u.3  Usp11  ubiquitin specific peptidase 11 
 rno-u.3  Usp15  ubiquitin specific peptidase 15 
 gga-u.3  USP4  ubiquitin specific peptidase 4 
 gga-u.3  USP15  ubiquitin specific peptidase 15 
 mcc-u.3  USP4  ubiquitin specific peptidase 4 
 mcc-u.3  USP11  ubiquitin specific peptidase 11 
 cfa-u.3  USP4  ubiquitin specific peptidase 4 
 cfa-u.3  USP11  ubiquitin specific peptidase 11 
 cel-u.3  H34C03.2  Ubiquitin carboxyl-terminal hydrolase 
 sce-u.3  UBP12  putative ubiquitin-specific protease UBP12 

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Top 50 coexpressed genes to usp4 (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre3050   Proteasome  6 53 6.72
 dre4141   Protein processing in endoplasmic reticulum  6 198 5.06
 dre4120   Ubiquitin mediated proteolysis  5 156 4.40
 dre4144   Endocytosis  4 324 2.09
 dre4068   FoxO signaling pathway  2 181 -

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dre:usp4 (ubiquitin specific peptidase 4 (proto-oncogene)) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID
Other ID LINK Target Reference

dre-u.3
for
usp4


dre-r.3
for
usp4


dre-u.3
for
usp15


dre-u.3
for
usp11


hsa-u.4
for
USP15


hsa-u.4
for
USP4


hsa-u.4
for
USP11


mmu-u.4
for
Usp4


mmu-u.4
for
Usp11


rno-u.3
for
Usp4


rno-u.3
for
Usp11


rno-u.3
for
Usp15


gga-u.3
for
USP4


gga-u.3
for
USP15


mcc-u.3
for
USP4


mcc-u.3
for
USP11


cfa-u.3
for
USP4


cfa-u.3
for
USP11


cel-u.3
for
H34C03.2


sce-u.3
for
UBP12

1 psmd11b proteasome 26S subunit, non-ATPase 11b 322265 7.7 4.0
2.4
1.1
1.2
-0.2
0.5
-0.7
1.8
2.5
-1.5
2.8
-0.2
2.7
1.3
1.9
3.7
0.5
2.5
-0.1
3.4
-0.3
2 dnajc7 DnaJ (Hsp40) homolog, subfamily C, member 7 406579 7.6 4.0
0.4
0.9
1.9
0.8
0.1
2.0
0.7
3.0
0.4
2.0
0.4
2.8
2.7
-1.5
0.1
0.1

0.0
3 ube2g1a ubiquitin-conjugating enzyme E2G 1a (UBC7 homolog, yeast) 334133 7.5 3.9
-0.1
-0.2
1.5
-0.7
-0.3
-0.5
-0.9
0.7
-1.6
2.5
-1.6
3.1
0.2
3.0
0.3
-0.6
-0.0
2.0
5.1

4 abcf2a ATP-binding cassette, sub-family F (GCN20), member 2a 336770 7.4 3.9
1.1
0.3
1.1
-0.9
-0.3
0.3
1.7
3.7
-0.3
1.7
0.4
2.6
2.2
1.5
1.7
2.6
4.0
0.1
2.4
0.7
5 ppp6r3 protein phosphatase 6, regulatory subunit 3 324530 7.2 3.8
1.7
0.9
1.3
1.3
3.2
0.5
1.0
0.8
1.9
0.4
3.4
2.8
0.6
0.1
2.9
2.3
1.3
0.7
2.3
1.5
4.0
1.8
4.4
1.1
4.8
1.5
3.8
1.2
3.4
2.0
1.9
0.3
5.3
4.8
3.9
6 ppp2r2ab protein phosphatase 2, regulatory subunit B, alpha b 327263 6.7 3.5
1.5
0.1
2.4
0.9
2.7
1.1
1.8
0.5
2.1
0.0
0.5
0.5
1.3
0.8
2.3
1.0
1.4
-0.4
3.6
1.1
0.6
0.6
3.7
3.4
0.9
0.8
1.8
1.6
0.4
0.1
2.2
-0.0
3.9
-0.0
7 naa25 N-alpha-acetyltransferase 25, NatB auxiliary subunit 568789 6.5 3.4
4.0
1.4
4.9
0.3
-0.1
1.6
-1.0
2.8
-1.3
2.9
1.5
3.5
0.6
1.5
-1.7
0.8
6.7
0.8
8 cul1a cullin 1a 323883 6.5 3.4
2.8
1.6
1.9
0.8
1.0
-0.1
1.4
1.8
-0.8
3.2
0.6
4.2
0.1
5.7
4.6
-0.2
2.7
1.0
3.3
-1.1
-0.6
9 eif4g2a eukaryotic translation initiation factor 4, gamma 2a 323453 6.4 3.4
2.1
0.6
0.2
-0.2
-0.0
1.2
1.5
2.5
-1.7
1.1
-1.4
2.3
-0.1
2.4
1.9
-0.9
0.5
-1.3

3.6
10 uba1 ubiquitin-like modifier activating enzyme 1 406335 6.3 3.3
0.4
-0.4
2.3
1.8
3.5
-0.2
2.8
1.7
8.3
2.0
5.3
1.5
3.0
1.4
3.5
0.9
5.0
0.5
1.9
0.3
1.9
-0.1
3.3
-2.0
1.3
0.6
5.1
1.9
2.4
2.3
6.4
-0.0
5.4
0.4
11 edc4 enhancer of mRNA decapping 4 565659 6.3 3.3
1.0
2.3
0.3
0.2
3.8
4.0
2.0
0.5
2.0
-0.4
1.7
1.3
0.2
1.8
2.5
3.5
3.1

12 psmd1 proteasome 26S subunit, non-ATPase 1 554967 6.3 3.3
3.7
0.3
1.2
1.9
0.5
4.5
-0.6
3.6
0.5
3.5
3.7
1.6
2.8
1.6
0.5
-1.9
2.6
0.1
13 ap2a1 adaptor related protein complex 2 subunit alpha 1 558153 6.2 3.3
0.2
0.6
1.0
-0.7
2.7
1.2
1.2
0.9
3.5
1.3
1.3
-0.4
3.6
2.4
1.7
1.6
3.0
0.9
0.2
1.5
1.6
1.6
1.8
1.3
2.8
2.5
0.8
0.3
2.5
1.5
14 zzef1 zinc finger, ZZ-type with EF hand domain 1 566682 6.2 3.3
1.0
1.6
1.7
3.3
-0.0
3.2
-0.4
-0.1
-2.0
-0.8
1.7
2.1
2.4
0.5
2.2
1.4


15 ubqln4 ubiquilin 4 334337 6.1 3.2
2.2
0.4
2.8
0.6
2.4
0.8
3.9
1.0
2.3
1.9
1.9
1.0
3.3
1.0
2.4
1.5
2.0
1.6
2.3
0.5
1.9
0.5
2.0
1.5
2.6
1.8
1.5
1.0
3.5
1.5
2.5
-0.4
16 ube3a ubiquitin protein ligase E3A 792398 6.0 3.2
3.3
1.7
0.1
-1.4
0.5
0.7
-0.4
0.6
0.4
3.0
1.2
4.9
1.5
0.0
-2.0
-0.6


17 naa30 N-alpha-acetyltransferase 30, NatC catalytic subunit 100192212 5.9 3.1
1.3
3.3
0.4
-1.6
0.1
-0.2
-0.2
0.6
-0.2
2.9
-0.2
1.1
0.8
-0.7
-0.3
-0.7
-0.5
0.6
18 usp14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 335736 5.8 3.1
1.3
0.0
-0.5
-0.8
0.8
1.2
0.5
0.8
2.4
2.8
-0.4
1.0
0.2
2.1
0.3
-0.5
4.2
-0.5
19 eif4enif1 eukaryotic translation initiation factor 4E nuclear import factor 1 541411 5.8 3.0
1.7
3.8
-0.3
2.5
2.2
2.1
0.8
2.2
1.7
1.7
0.4
1.2
1.6
1.0
1.2
2.3
6.9

20 psmd11a proteasome 26S subunit, non-ATPase 11a 503934 5.7 3.0
2.4
1.1
1.2
-0.2
0.5
-0.7
1.8
2.5
-1.5
2.8
-0.2
2.7
1.3
1.9
3.7
0.5
2.5
-0.1
3.4
-0.3
21 psmb5 proteasome 20S subunit beta 5 30387 5.7 3.0
1.3
-0.5
1.6
-0.2
0.5
-0.7
0.6
-0.4
1.3
-0.6
0.3
-0.8
0.1
-1.6
-0.3
-0.5
0.3
-0.9
0.5
-0.9
1.4
-0.0
1.5
0.5
1.5
-1.0
1.5
0.8
0.7
-1.4
3.6
-0.0
22 dnajc11a DnaJ (Hsp40) homolog, subfamily C, member 11a 322953 5.7 3.0
-0.2
-1.2
2.0
1.3
0.6
2.6
1.4
3.8
-0.7
2.4
-0.8
2.6
4.5
1.9
0.3
3.1
3.8
-0.8
1.2

23 nrbp1 nuclear receptor binding protein 1 569806 5.6 3.0
-0.0
2.9
1.0
1.6
3.3
4.2
1.6
1.7
1.7
1.2
2.0
2.1
1.9
2.7
2.5
4.3
4.5

24 eif4g1a eukaryotic translation initiation factor 4 gamma, 1a 572435 5.6 2.9
2.4
2.4
3.8
3.5
0.7
0.3
0.7
2.3
-1.2
3.4
3.3
0.1
-1.1
2.5
2.4
1.8
1.7
1.1
-0.4
3.2
1.7
3.0
2.3
1.6
-0.0
1.6
-1.3
4.2
1.4
25 dnajc10 DnaJ (Hsp40) homolog, subfamily C, member 10 557858 5.5 2.9
0.4
1.3
-0.5
-1.2
-0.8
1.1
0.3
0.7
1.9
2.1
-0.3
-0.3
0.8
-0.6
-1.7
-0.7
-0.6

26 cltcb clathrin, heavy chain b (Hc) 503600 5.5 2.9
1.7
0.6
1.2
0.5
0.7
0.1
0.8
0.8
0.7
-0.7
3.7
0.0
0.6
1.3
1.7
2.5
1.2
1.2
0.5
0.2
-0.1
2.0
-1.1
-0.4
-1.4
0.4
-0.2
3.4
1.4
27 dpp9 dipeptidyl-peptidase 9 768170 5.4 2.9
0.9
1.9
2.6
0.9
1.8
0.6
0.2
-0.4
3.5
1.6
0.5
-0.2
4.6
2.2
0.2
-1.1
2.4
0.8
2.0
1.5
2.6
0.4
3.4
0.3
0.1
-0.1
2.4
1.9
-0.4
-2.4
4.8

28 kcmf1 potassium channel modulatory factor 1 393927 5.4 2.8
4.6
2.9
0.6
0.7
-1.8
-0.2
-2.0
2.5
-1.6
4.2
0.8
0.4
2.4
1.0
0.3
-0.4
0.8
1.2
0.6

29 prmt1 protein arginine methyltransferase 1 321974 5.4 2.8
-0.5
-0.7
0.1
-0.0
-0.7
-0.4
3.8
0.8
0.0
0.8
0.8
0.5
-0.0
2.4
0.3
-0.6
-1.2
-0.7
0.9
1.7
-0.1
2.2
-0.2
1.5
0.8
0.5
-0.5
30 gnb1b guanine nucleotide binding protein (G protein), beta polypeptide 1b 406796 5.4 2.8
0.7
0.5
1.8
1.4
2.6
1.0
3.0
0.8
2.4
2.1
2.7
1.9
2.3
1.5
2.4
2.0
1.7
1.1
0.2
-0.4
-0.2
-0.4
3.0
1.6
1.9
1.8
2.5
0.8
2.4
0.3
2.8
2.4
1.7
-1.4
-0.5
31 psme4b proteasome activator subunit 4b 553346 5.3 2.8
1.7
1.2
2.0
0.3
3.3
0.4
-0.6
2.2
-2.8
1.5
-2.0
6.0
3.9
5.1
0.3
-0.5
0.2
0.6
4.5
1.0
3.0
32 psme3 proteasome activator subunit 3 30649 5.3 2.8
-0.8
-0.4
0.5
1.5
1.4
2.4
0.4
0.9
1.2
1.4
0.2
-0.7
-0.4
1.6
4.7
-0.2
2.4

33 usp10 ubiquitin specific peptidase 10 564632 5.3 2.8
1.1
0.2
0.5
1.0
0.8
2.4
0.2
1.2
1.5
2.0
1.2
2.1
2.0
1.0
1.7
-0.1

3.6
34 ube4b ubiquitination factor E4B, UFD2 homolog (S. cerevisiae) 170784 5.3 2.8
1.0
1.7
-0.6
3.0
-0.4
1.7
1.4
3.2
0.8
0.5
1.0
1.3
1.3
-0.4
0.7
0.7
3.0
0.6
35 usp7 ubiquitin specific peptidase 7 (herpes virus-associated) 553758 5.2 2.8
0.6
1.7
2.2
0.8
0.3
2.9
-0.8
2.6
-0.4
3.7
1.2
3.6
2.0
0.6
1.2
2.5
2.5
1.1
36 srm spermidine synthase 394009 5.2 2.7
1.3
0.2
-0.4
-0.3
0.6
-0.6
-0.6
-0.7
-0.4
0.1
-0.1
0.5
-1.1
3.4
-0.6
-0.4
-0.4
-0.0
-0.1
37 vcp valosin containing protein 327197 5.2 2.7
4.2
2.9
-0.5
-0.6
2.1
0.7
1.2
0.9
2.6
-0.9
5.4
1.5
0.3
0.2
3.6
1.9
1.2
0.3
3.0
2.6
2.8
1.6
0.5
-0.3
1.6
0.2
2.3
-0.9
1.5
1.4
-0.9
-1.8
3.6
2.8
2.0
0.4
38 LOC100332095 la-related protein 4 100332095 5.2 2.7
2.9
2.8
1.9
-0.1
3.9
0.4
-0.5
2.5
-0.8
-1.6
-1.9
0.1
-0.3
-1.2
-1.8
3.2
1.3
2.2
0.5
4.8
1.1
4.7
1.8
-0.4
-0.5
2.4
1.4
0.3
-2.3
1.0

39 pafah1b1b platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b 394247 5.2 2.7
1.3
-0.6
0.2
-0.5



2.2
0.6
1.5
0.5
3.8
0.8
3.8
2.4
0.6
0.1
0.9
3.0

40 naa15b N-alpha-acetyltransferase 15, NatA auxiliary subunit b 334099 5.2 2.7
1.5
0.8
2.3
0.2
2.6
2.2
0.9
-0.8
-0.6
-0.7
0.5
-1.2
-1.4
-1.9
2.4
-0.5
-1.6
-1.8
5.4
2.4
1.2
0.0
4.0
2.4
1.2
0.2
0.9
-1.3
1.3
-0.2
0.0
-2.1
2.5
0.2
41 tpp2 tripeptidyl peptidase 2 100331669 5.2 2.7
1.0
2.4
1.3
1.2
0.2
1.3
-0.9
2.7
-0.1
4.3
1.0
6.5
2.1
0.6
2.0
-0.8
4.4

42 prrc2a proline-rich coiled-coil 2A 394248 5.1 2.7
3.4
0.4
0.2
-0.3
-0.2
2.2
3.3
0.3
3.3
1.5
3.6
-1.7
1.7
0.4
2.5
3.5
1.6
1.1
-1.6

43 clptm1 CLPTM1 regulator of GABA type A receptor forward trafficking 795480 5.1 2.7
1.5
0.2
-0.1
0.6
2.6
2.9
0.5
3.0
2.0
1.9


-0.1
2.6
1.7
1.5
2.0
0.8

44 ahsa1b AHA1, activator of heat shock protein ATPase homolog 1b 321945 5.1 2.7
0.2
-0.7
1.5
0.1
-0.4
0.1
1.8
-0.1
-0.5
-0.4
-0.6
0.4
0.1
-0.9
-1.8
0.9
0.6
1.6
-0.8
0.6
0.5
1.8
-0.5
0.4
-0.6
0.2
1.1
1.2
-0.4
-0.8
45 tbrg4 transforming growth factor beta regulator 4 562388 5.1 2.7
3.5
-0.2
1.3
0.1
1.6
2.3
-1.3
0.0
-0.5
1.7
1.1
-0.6
1.1
1.2
1.4
-0.5


46 kif5ba kinesin family member 5B, a 563459 5.1 2.7
1.3
0.8
1.3
0.2
1.6
0.3
0.2
-0.2
1.5
0.3
-0.0
-0.1
0.8
0.8
1.4
0.8
0.8
0.6
2.5
0.5
1.6
-0.5
3.6
1.6
1.3
0.3
1.1
0.8
0.5
-0.0
1.9
-0.2
1.0

47 bag6 BCL2 associated athanogene 6 83910 5.1 2.7
3.6
-1.1
2.0
-0.7
1.5
2.7
3.7
0.9
3.8
2.5
1.7
0.2
0.8
2.6
2.6
0.9
5.6


48 eif4e1c eukaryotic translation initiation factor 4E family member 1c 550549 5.1 2.7
1.1
0.3
0.7
-0.1
1.7
-0.1
-0.7
-0.1
-0.4
-0.2
-0.3
0.2
0.9
2.4
0.0
2.7
0.8
-0.7
0.3
0.3
-0.4
-1.7
3.5
0.9
0.6
49 cltca clathrin, heavy chain a (Hc) 323579 5.1 2.7
1.7
0.6
1.2
0.5
0.7
0.1
0.8
0.8
0.7
-0.7
3.7
0.0
0.6
1.3
1.7
2.5
1.2
1.2
0.5
0.2
-0.1
2.0
-1.1
-0.4
-1.4
0.4
-0.2
3.4
1.4
50 abce1 ATP-binding cassette, sub-family E (OABP), member 1 406324 5.1 2.7
2.1
-1.4
1.2
-1.4
-0.5
3.2
-1.5
1.5
-1.9
3.7
1.4
2.5
-0.2
-0.1
1.5
-1.1
2.9
0.4
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