Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3   esco2   establishment of sister chromatid cohesion N-acetyltransferase 2 
 dre-r.3   esco2   establishment of sister chromatid cohesion N-acetyltransferase 2 
 dre-m.5   esco2   establishment of sister chromatid cohesion N-acetyltransferase 2 
 dre-u.3   esco1   establishment of sister chromatid cohesion N-acetyltransferase 1 
 hsa-u.4   ESCO1   establishment of sister chromatid cohesion N-acetyltransferase 1 
 hsa-u.4   ESCO2   establishment of sister chromatid cohesion N-acetyltransferase 2 
 mmu-u.4   Esco1   establishment of sister chromatid cohesion N-acetyltransferase 1 
 mmu-u.4   Esco2   establishment of sister chromatid cohesion N-acetyltransferase 2 
 rno-u.3   Esco1   establishment of sister chromatid cohesion N-acetyltransferase 1 
 rno-u.3   Esco2   establishment of sister chromatid cohesion N-acetyltransferase 2 
 gga-u.3   ESCO1   establishment of sister chromatid cohesion N-acetyltransferase 1 
 gga-u.3   ESCO2   establishment of sister chromatid cohesion N-acetyltransferase 2 
 mcc-u.3   ESCO1   establishment of sister chromatid cohesion N-acetyltransferase 1 
 mcc-u.3   ESCO2   establishment of sister chromatid cohesion N-acetyltransferase 2 
 cfa-u.3   ESCO1   establishment of sister chromatid cohesion N-acetyltransferase 1 
 cfa-u.3   ESCO2   establishment of sister chromatid cohesion N-acetyltransferase 2 
 dme-u.3   eco   Establishment of cohesion 
 cel-u.3   F08F8.4   Uncharacterized protein 
 sce-u.3   ECO1   Eco1p 

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Top 50 coexpressed genes to esco2 (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre3030   DNA replication  10 38 7.46
 dre4110   Cell cycle  9 153 7.04
 dre3430   Mismatch repair  4 22 6.64
 dre3420   Nucleotide excision repair  4 44 5.39
 dre240   Pyrimidine metabolism  4 69 4.61

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dre:esco2 (establishment of sister chromatid cohesion N-acetyltransferase 2) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dre-u.3
for
esco2
dre-r.3
for
esco2
dre-m.5
for
esco2
dre-u.3
for
esco1
hsa-u.4
for
ESCO1
hsa-u.4
for
ESCO2
mmu-u.4
for
Esco1
mmu-u.4
for
Esco2
rno-u.3
for
Esco1
rno-u.3
for
Esco2
gga-u.3
for
ESCO1
gga-u.3
for
ESCO2
mcc-u.3
for
ESCO1
mcc-u.3
for
ESCO2
cfa-u.3
for
ESCO1
cfa-u.3
for
ESCO2
dme-u.3
for
eco
cel-u.3
for
F08F8.4
sce-u.3
for
ECO1
1 chtf18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) 554366 10.8 6.4
 3.4
 -0.4
 -1.3
 1.1
 -0.9
 3.7
 -2.2
 4.7
 0.1
 4.6
 -0.6
 1.5
 -0.2
 2.4
 3.7
 1.9
 3.9
2 ncapg non-SMC condensin I complex, subunit G 492707 10.6 5.3
 4.4
 -1.2
 0.4
 11.5
 2.3
 13.5
 1.2
 8.5
 1.4
 4.9
 0.4
 8.4
 -1.8
 8.0
 2.8
-0.3
3 ncapg2 non-SMC condensin II complex, subunit G2 100037337 10.4 5.4
-1.8
 -1.3
 5.2
 0.6
 8.7
 0.2
 5.4
 -0.3
 4.1
 -0.4
 6.0
 -0.5
 6.6
2.0
4 zgc:110540 zgc:110540 541538 10.4 5.2
 4.2
 -2.2





-1.1
 3.0






5 pcna proliferating cell nuclear antigen 30678 10.2 6.0
 3.3
 -1.5
 -0.9
 5.0
 0.2
 3.3
 -0.6
 3.6
 0.5
 4.4
 1.7
 4.3
 0.1
 4.3
 2.1
-1.3
 1.2
 3.6
6 ccna2 cyclin A2 192295 10.1 5.6
 3.6
 1.0
-2.0
 -0.1
-0.3
 6.8
-0.3
 0.5
 10.9
 0.6
0.1
 9.8
0.8
 0.2
-0.5
 2.7
1.1
 -0.7
-0.7
 7.3
-0.3
 0.2
 8.4
 1.0
 0.7
7 chaf1b chromatin assembly factor 1, subunit B 406285 9.8 5.6
 3.4
 -0.5
 -1.4
 4.1
 -1.3
 4.5
 -2.4
 4.6
 0.0
 2.4
 -1.9
 3.0
 -1.0
 3.5
 2.8
 1.8
 5.1
8 ncaph non-SMC condensin I complex, subunit H 570062 9.5 5.7
 3.0
 -0.7
 -0.2
 8.4
 -1.4
 9.2

-1.4
 4.8
 1.5
 5.7
 -0.6
 6.1
 3.5
2.6
9 chaf1a chromatin assembly factor 1, subunit A (p150) 563212 9.5 5.0
-1.4
 -0.3
 4.0
 -0.8
 4.4
 -1.8
 5.4
 0.3
 3.5
 0.3
 4.0
 -1.1
 3.6
 4.5
 5.5
10 tyms thymidylate synthetase 81540 9.4 5.0
 3.5
 -1.0
 -0.6
 6.2
 -1.7
 4.7
 0.5
 3.0
 -1.3
 2.5
 -0.1
 6.3
 0.7
 3.1
 2.9
 1.0
 4.4
11 mcm4 minichromosome maintenance complex component 4 337598 9.4 4.8
 3.8
 -1.5
 -1.7
 6.6
 -0.4
 4.0
 -0.9
 5.8
 -0.0
 5.8
 -0.6
 4.3
 -1.6
 3.7
 3.8
 1.4
 1.3
12 wdhd1 WD repeat and HMG-box DNA binding protein 1 436999 9.3 3.7
 4.8
 0.4
 2.4
 5.4
 -1.0
 4.4
 -2.0
 5.9
 -1.3
 3.7
 -0.4
 6.2
 1.4
 4.1
 5.2
 1.9
 4.4
13 haus4 HAUS augmin-like complex, subunit 4 436698 9.2 4.6
 3.8
 -0.8
 -1.1
 0.0
 -0.1
 3.3
 -0.7
 5.3
 -0.7
 2.9
 -0.7
 2.1




14 rrm2 ribonucleotide reductase M2 polypeptide 30733 9.2 4.4
 4.0
 0.4
0.2
 1.9
-1.5
 11.2
0.9
 2.9
-0.4
 10.0
0.4
 3.2
-0.3
 6.8
5.0
 0.5
-1.1
 4.2
1.1
 1.1
-0.9
 8.0
-0.9
 1.2
-0.2
 5.6
0.4
 3.8
 1.1
 0.5
0.2
15 ncapd3 non-SMC condensin II complex, subunit D3 556493 9.2 4.9
 3.5
 -0.8
 -2.4
 3.6
 1.2
 3.9
 -0.2
 3.7
 -1.7
 3.8
 -0.7
 1.6
 1.6
 2.6
0.8
16 krcp kelch repeat-containing protein 323406 9.2 4.8
 3.6
 -0.2
-0.9














17 cdca7a cell division cycle associated 7a 550236 9.0 4.2
 4.0
 -1.3
 -1.4
 3.1
 -1.1
 3.1
 -1.0
 3.3
 -0.7
 4.6
 -0.4
 4.0
 0.4
 3.3


18 mybl2b v-myb avian myeloblastosis viral oncogene homolog-like 2b 445390 9.0 5.2
 3.0
 4.5
0.0
 -0.5
-0.6
 7.1
4.3
 0.4
0.1
 5.4
5.2
 1.3
0.2
 3.9
3.1
 2.3
0.9
 4.1
3.2
 0.9
-0.3
 6.7
2.5
 0.8
0.4
 5.9
3.6


19 smc2 structural maintenance of chromosomes 2 321452 8.9 4.9
 3.2
 -0.4
 1.2
 6.2
 2.7
 7.3
 0.8
 5.9
 -1.1
 2.5
 0.6
 7.0
 -0.9
 4.2
 1.7
 0.0
 1.7
20 mis12 MIS12 kinetochore complex component 393349 8.9 5.1
 3.0
 -1.6
 1.9
 1.1
 3.3
 1.6
 0.9
 0.7
 -1.3
 4.6
 -0.7
 -0.2
 -0.7
 2.4


21 cdca5 cell division cycle associated 5 559398 8.8 5.0
 3.1
 -1.7
 -0.6
 7.5
 -0.1
 11.7



-1.4
 5.9




22 ncaph2 non-SMC condensin II complex, subunit H2 562678 8.8 4.6
-0.9
 -1.5
 1.4
 -1.1
 1.2
 -0.6
 1.6
 -1.9
 1.4
 -1.8
 1.6
 -0.6
 -0.9
1.1
23 slbp stem-loop binding protein 407727 8.8 3.7
 4.3
 0.4
0.3
 0.2
 1.9
 1.7
 3.9
 0.4
 2.8
 1.5
0.3
 2.9
1.0
 1.5
 2.7
 0.5
 1.5
 3.8
 0.1
24 cdc6 cell division cycle 6 homolog (S. cerevisiae) 402825 8.8 3.9
 4.1
 0.4
 -0.4
 9.0
 -0.8
 7.3
 -1.2
 4.7
 -1.5
 3.3
 -0.7
 6.5
 -0.6
 6.9
 2.4
 0.5
 2.3
25 prim1 DNA primase subunit 1 30440 8.7 4.7
 3.3
 -1.7
 -0.4
 2.9
 -0.5
 5.7
 -0.8
 4.4
 1.1
 3.2
 0.8
 2.8
 0.3
 4.5
 1.7
 2.7
1.3
 1.9
26 mcm5 minichromosome maintenance complex component 5 286747 8.6 4.5
 3.4
 -1.8
 -1.6
 3.1
 -1.0
 5.9
 -2.5
 6.4
 -1.7
 6.3
 -0.3
 4.2
 -1.5
 5.9
 3.5
 0.4
 2.1
27 fen1 flap structure-specific endonuclease 1 386707 8.6 4.4
 3.5
 -0.1
 -1.1
 4.8
 -0.6
 3.8
 -2.2
 4.6
 -2.5
 3.9
 0.8
 3.1
 -0.7
 3.3
 1.8
 1.9
 4.6
28 spc25 SPC25 component of NDC80 kinetochore complex 100144563 8.6 4.5
-0.7
 -0.9
 10.7
 0.6
 9.5
 -0.5
 8.1
 -0.1
 2.2
 -0.5
 9.4
 0.6
 6.4


29 ercc6l excision repair cross-complementation group 6-like 100005291 8.6 4.6
 3.3
 0.2
 0.1
 7.0
 1.1
 8.1
 -1.2
 7.7
 -1.0
 2.6
 -0.7
 7.7
 -0.5
 6.8


30 nasp nuclear autoantigenic sperm protein (histone-binding) 799570 8.5 4.3
 3.5
 0.2
 -0.1
 0.2
 0.1
 1.7
 0.0
 2.8
 0.4
 3.6
 0.5
 3.0
 -0.3
 2.0
 0.1
 4.0
1.7
31 cdk2 cyclin-dependent kinase 2 406715 8.5 4.4
 3.4
 2.0
1.5
 2.6
1.7
 10.4
2.8
 2.7
1.3
 10.3
4.9
 3.1
2.6
 7.8
2.2
 2.0
0.6
 3.9
2.2
 5.2
2.9
 6.3
2.3
 1.7
1.7
 6.8
2.7
 2.6
2.2
 1.9
0.5
 3.0
1.0
32 cenpi centromere protein I 558570 8.5 4.4
-0.7
 -0.9
 8.0
 -0.6
 9.2
 -0.6
 8.8
 -0.6
 4.1
 0.6
 6.2
 0.5
 8.7


33 zwilch zwilch kinetochore protein 336439 8.4 4.5
 3.2
 -0.7
 0.2
 4.4
 -1.4
 8.3
 0.2
 5.2
 -1.0
 2.4
 0.6
 4.9
 0.0
 3.7
 -0.0
 0.7
34 uhrf1 ubiquitin-like with PHD and ring finger domains 1 406350 8.3 4.1
 3.5
 -2.9
 -2.6
 6.0
 -0.3
 8.8
 -0.9
 6.8
 -0.2
 3.0
 -1.2
 5.4
 -0.9
 4.4


35 chek1 checkpoint kinase 1 393162 8.3 4.5
 3.1
 -0.6
 -0.5
 6.8
 0.6
 9.5
 0.8
 3.4
 -1.1
 4.5
 -0.2
 4.6
 0.2
 5.1
 -0.8
 1.6
-0.5
 -0.5
-1.8
36 rrm1 ribonucleotide reductase M1 polypeptide 30740 8.3 4.5
 3.0
 0.0
 -1.9
 4.2
 -1.2
 3.3
 -2.9
 5.5
 -0.5
 5.3
 0.0
 3.2
 -1.2
 5.1
 3.3
 -0.7
 2.9
0.2
37 pbk PDZ binding kinase 360218 8.3 4.3
-0.5
 -1.0
 12.4
 -0.5
 13.7
 -0.3
 8.7
 -1.1
 5.6
 -0.1
 3.4
 -1.1
 12.5
 -2.5

38 si:dkey-6i22.5 si:dkey-6i22.5 564240 8.3 4.5
 3.1
 -0.5
 -0.5
 -0.5
 -1.0
 1.5
 -1.5
 4.7
 -0.4
 2.6
 0.1
 1.5




39 cenph centromere protein H 567359 8.2 4.3
















40 pola2 polymerase (DNA directed), alpha 2 322059 8.1 3.8
 3.7
 0.9
 -3.0
 2.9
 -0.2
 1.5
 -1.4
 2.7
 -1.8
 2.5
 -0.6
 2.6
 -1.7
 2.2
 3.7
 0.4
 4.2
41 rfc4 replication factor C (activator 1) 4 406435 8.1 4.1
 3.4
 -1.4
 -0.1
 2.4
 0.4
 4.3
 0.9
 5.1
 -0.6
 2.6
 -0.8
 1.5
 0.6
 3.2
 2.9
 3.5
 -0.8
42 ncapd2 non-SMC condensin I complex, subunit D2 552978 8.1 4.2
-0.6
 -2.2
 1.6
 -1.1
 4.8
 -1.6
 6.2
 -0.7
 6.1
 -1.7
 3.8
 -1.3
 3.7
 2.8
 -0.7
 0.7
43 ttk ttk protein kinase 317763 8.1 4.9
 2.5
 -0.8
 1.6
 9.2
 -0.1
 11.5
 1.0
 8.3
 0.9
 3.6
 0.5
 7.1
 -0.3
 10.3
 2.3
-0.0
44 e2f8 E2F transcription factor 8 565952 8.0 5.3
 2.0
 -0.3
 -0.7
 9.6
 -0.8
 7.9
 -1.2
 6.1
 0.8
 3.6
 -0.6
 6.0
 -0.9
 6.6


45 rpa2 replication protein A2 65226 8.0 4.5
 2.8
 -0.8
 -0.6
 -0.3
 -0.1
 2.6
 -0.7
 5.1
 -1.8
 2.4
 0.5
 0.9
 1.1
 2.7
 1.1
 1.7
1.1
 4.7
46 dtl denticleless E3 ubiquitin protein ligase homolog (Drosophila) 192314 7.9 4.5
 2.7
 0.2
 -0.8
 11.6
 -1.3
 7.8
 -0.9
 6.4
 -1.1
 4.3
 -0.4
 5.4
 -0.5
 5.7
 3.9
 1.4
47 atad5a ATPase family AAA domain containing 5a 560591 7.9 4.6
 2.7
 2.1
1.6
 1.8
 5.6
 -1.1
 5.5
 0.1
 6.4
 1.2
 4.1
 3.7
 5.2
 1.7
 4.4
 6.4
3.8
48 ndc80 NDC80 kinetochore complex component 445386 7.9 4.0
 3.3
 0.6
 2.0
 6.3
 0.2
 10.9
 -0.3
 7.6
 -0.7
 2.6
 0.4
 6.5
 0.6
 8.0
4.2
 1.3
49 mcm3 minichromosome maintenance complex component 3 192323 7.9 3.6
 3.6
 -0.5
-1.2
 -2.3
 2.9
 -1.5
 4.9
 -2.5
 5.5
 -2.3
 3.9
 -0.7
 4.4
 -0.4
 5.7
 2.6
 1.1
 1.1
50 pold1 polymerase (DNA directed), delta 1, catalytic subunit 556456 7.9 4.8
 2.4
 0.0
 -0.8
 1.3
 -0.9
 2.8
 -2.7
 5.5
 -1.3
 2.8
 1.0
 1.2
 -1.0
 2.8
 4.3
 1.1
 2.6
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