Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3   cyp8b1   cytochrome P450, family 8, subfamily B, polypeptide 1 
 dre-r.3   cyp8b1   cytochrome P450, family 8, subfamily B, polypeptide 1 
 dre-m.5   cyp8b1   cytochrome P450, family 8, subfamily B, polypeptide 1 
 dre-u.3   cyp8b2   cytochrome P450, family 8, subfamily B, polypeptide 2 
 dre-u.3   cyp8b3   cytochrome P450, family 8, subfamily B, polypeptide 3 
 hsa-u.4   CYP8B1   cytochrome P450 family 8 subfamily B member 1 
 mmu-u.4   Cyp8b1   cytochrome P450, family 8, subfamily b, polypeptide 1 
 rno-u.3   Cyp8b1   cytochrome P450 family 8 subfamily B member 1 
 mcc-u.3   CYP8B1   cytochrome P450 family 8 subfamily B member 1 
 cfa-u.3   CYP8B1   cytochrome P450 family 8 subfamily B member 1 

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Top 50 coexpressed genes to cyp8b1 (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre140   Steroid hormone biosynthesis  11 53 6.72
 dre1240   Biosynthesis of cofactors  11 179 6.58
 dre980   Metabolism of xenobiotics by cytochrome P450  9 58 6.52
 dre982   Drug metabolism - cytochrome P450  8 55 6.64
 dre830   Retinol metabolism  8 66 6.23

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dre:cyp8b1 (cytochrome P450, family 8, subfamily B, polypeptide 1) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dre-u.3
for
cyp8b1
dre-r.3
for
cyp8b1
dre-m.5
for
cyp8b1
dre-u.3
for
cyp8b2
dre-u.3
for
cyp8b3
hsa-u.4
for
CYP8B1
mmu-u.4
for
Cyp8b1
rno-u.3
for
Cyp8b1
mcc-u.3
for
CYP8B1
cfa-u.3
for
CYP8B1
1 cyp8b3 cytochrome P450, family 8, subfamily B, polypeptide 3 447848 8.4 3.5
 4.2
 13.3
6.3
 13.3
8.4




2 shbg sex hormone-binding globulin 322604 7.7 2.6
 4.5
 0.9
 1.5

-0.0
 1.8
3 cyp7a1 cytochrome P450, family 7, subfamily A, polypeptide 1 394148 7.5 3.9
2.5
 2.4
7.6
 4.2

4 ugt5d1 UDP glucuronosyltransferase 5 family, polypeptide D1 100415794 6.4 3.4
1.7
1.1
 1.5
1.5
 4.5
4.3
 6.2
6.0
 2.3
2.0
 5.2
5.1
 2.3
0.4
5 kmo kynurenine 3-monooxygenase 368242 6.4 2.5
 3.4
 1.8
 1.8
 2.9
 2.7
 0.4
 1.3
 2.0
6 tdo2a tryptophan 2,3-dioxygenase a 100008541 6.4 2.9
 3.0
 0.6
-0.6
 0.6
0.4
 2.1
 3.5
 1.3
 1.2
7 cyp8b2 cytochrome P450, family 8, subfamily B, polypeptide 2 100004274 6.3 3.3
13.3
6.3
 13.3
8.4




8 si:ch211-288g17.4 si:ch211-288g17.4 795729 6.2 2.5
 3.2






9 sec14l7 SEC14-like lipid binding 7 566865 6.1 3.2
1.9
0.9
 1.0
0.0
 1.9
0.9
 3.1
2.7
 1.2
0.4
 3.5
0.4
 1.4
0.9
10 serpinf2a serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a 560308 6.0 2.5
 3.1
 0.8
-0.2
 0.7
-0.1
 4.6
 3.7
 2.0
 1.3
 1.3
11 adamts13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 100320289 6.0 3.1
0.7
 1.3

1.7
 0.7
12 asgrl1 asialoglycoprotein receptor-like 1 100000463 5.6 2.9
2.6
1.4
 2.1
0.7
 3.3
2.1
 4.6
4.2
 3.0
1.5
 2.4
1.8
 1.7
1.0
13 abcb11b ATP-binding cassette, sub-family B (MDR/TAP), member 11b 571189 5.6 2.9
1.0
0.1
 1.3
0.5
 2.2
0.7
 5.2
3.0
 1.4
1.1
 1.8
1.6
 -0.1
-0.7
14 gja12.1 gap junction protein, alpha 12.1 492358 5.5 2.9
0.4
-0.5
 0.7
-0.1
 -0.4
 -0.1
 -0.1
 0.3
15 acsbg1 acyl-CoA synthetase bubblegum family member 1 100006023 5.5 2.9
1.7
0.6
 2.0
1.0
 -0.4
 -0.6
 0.4
0.0
 0.7
-0.5
 0.1
16 kynu kynureninase 100334830 5.3 2.8
1.2
 1.2
 0.8
 3.2
 2.9
 0.8
 0.3
17 gcshb glycine cleavage system protein H (aminomethyl carrier), b 436852 5.2 1.9
 2.9
 2.5
-0.6
 2.0
-0.2
 1.3
 0.1
 -0.1
 0.6
 0.6
18 cyb5r2 cytochrome b5 reductase 2 751641 5.2 2.7
1.9
0.9
 2.0
1.3
 0.2
0.0
 0.9
-1.2
 0.2
-0.4
 -0.2
-1.0
 0.1
-0.2
19 si:dkey-91i10.3 si:dkey-91i10.3 565876 5.1 2.7
4.6
2.9
 4.6
2.0
 1.4
0.5
 2.6
 1.2
 0.9
0.4
 2.3
1.0
20 LOC571431 epidermal growth factor receptor-like 571431 5.1 2.7
1.0
0.4
 1.1
0.7
 1.0
0.6
 1.6
-0.1
 0.8
0.1
 0.3
-0.0
 0.1
-0.6
21 LOC569025 alpha-2-macroglobulin-like protein 1 569025 5.1 2.7







22 cyp2k19 cytochrome P450, family 2, subfamily k, polypeptide 19 562304 5.0 2.7
 2.0
 2.3
1.1
 2.8
0.8




23 npc1l1 NPC1-like 1 100616532 5.0 2.6
0.3
-0.6
 0.2
-0.2
 -0.9
 0.5
0.1
 0.5
 -0.2
 1.0
-0.5
24 sult3st3 sulfotransferase family 3, cytosolic sulfotransferase 3 571461 4.9 2.6
3.9
1.8
 5.0
2.0
 3.5
2.3
 6.4
2.6
 3.4
2.3
 4.3
2.7
 2.2
1.2
25 uox urate oxidase 436604 4.9 1.8
 2.8
 0.1
 0.7
4.2
 2.9
 0.7
26 ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 641488 4.9 2.6
1.7
1.1
 1.5
1.5
 4.5
4.3
 6.2
6.0
 2.3
2.0
 5.2
5.1
 2.3
0.4
27 srd5a2a steroid-5-alpha-reductase, alpha polypeptide 2a 550398 4.9 2.0
 2.5
 2.5
 5.4
 4.1
-0.0
 1.4
0.7
 -0.1
 -0.7
 -1.2
28 si:dkey-105h12.2 si:dkey-105h12.2 100006782 4.8 1.8
 2.6






29 zgc:77748 zgc:77748 393832 4.8 2.5
-0.2
-0.7
 0.4
0.2
 -0.7
 0.5
 -0.1
 0.1
 -1.0
30 hpda 4-hydroxyphenylpyruvate dioxygenase a 394142 4.8 2.1
 2.3
 1.0
0.7
 2.3
-0.1
 3.5
 5.7
 0.7
 1.2
 2.1
31 ugt5b3 UDP glucuronosyltransferase 5 family, polypeptide B3 100415792 4.8 2.5
1.7
1.1
 1.5
1.5
 4.5
4.3
 6.2
6.0
 2.3
2.0
 5.2
5.1
 2.3
0.4
32 cyp2p9 cytochrome P450, family 2, subfamily P, polypeptide 9 393592 4.8 1.9
 2.6
 0.4
0.4
 0.8
0.6
 1.7
 5.1
0.2
 2.6
-0.1
 1.0
 1.2
33 si:ch73-15n24.1 si:ch73-15n24.1 322603 4.7 2.5







34 zgc:77938 zgc:77938 402939 4.6 2.4







35 ugt1ab UDP glucuronosyltransferase 1 family a, b 406731 4.6 2.4
1.7
1.1
 1.5
1.5
 4.5
4.3
 6.2
6.0
 2.3
2.0
 5.2
5.1
 2.3
0.4
36 ugt1a4 UDP glucuronosyltransferase 1 family, polypeptide A4 100384901 4.6 2.4
1.7
1.1
 1.5
1.5
 4.5
4.3
 6.2
6.0
 2.3
2.0
 5.2
5.1
 2.3
0.4
37 si:cabz01068815.1 si:cabz01068815.1 569661 4.6 1.9
 2.3
 2.1
 1.0
 0.9
 0.0
 -0.8
 -0.6
 1.1
38 fabp10a fatty acid binding protein 10a, liver basic 171481 4.5 2.3
 1.9
 1.0
 0.6




39 aqp8a.2 aquaporin 8a, tandem duplicate 2 563130 4.5 2.4
1.1
-0.1
 0.7
0.7
 1.5
 3.4
 2.6
1.9
40 hsd11b1lb hydroxysteroid (11-beta) dehydrogenase 1-like b 100333777 4.5 2.4
3.6
0.2
 3.2
0.8
 1.1
-0.3
 0.8
 0.6
-0.5
 0.7
-0.7
 0.4
-1.1
41 si:ch73-281k2.5 si:ch73-281k2.5 100002182 4.5 2.4







42 bfb complement component bfb 30489 4.4 1.6
 2.5






43 slco1d1 solute carrier organic anion transporter family, member 1D1 326845 4.4 2.2
 1.9
 2.7
1.9
 2.6
2.1
 2.6
1.7
 4.2
0.5
 4.5
-0.4
 3.4
2.2
 3.1
44 sult2st2 sulfotransferase family 2, cytosolic sulfotransferase 2 777793 4.4 2.2
 1.9
 3.9
1.8
 5.0
2.0
 3.5
2.3
 6.4
2.6
 3.4
2.3
 4.3
2.7
 2.2
1.2
45 si:zfos-411a11.2 si:zfos-411a11.2 100000156 4.4 2.0
 2.0
 0.9
0.4
 1.0
0.5
 4.2
3.7
 7.0
6.1
 5.9
3.0
 4.4
4.1
 2.8
2.6
46 pygl phosphorylase, glycogen, liver 493916 4.3 1.9
 2.1






47 tm7sf2 transmembrane 7 superfamily member 2 494054 4.3 2.3
2.0
1.7
 2.1
1.7
 0.7
0.2
 1.3
0.7
 0.9
0.1
 1.0
0.2
 0.5
0.2
48 bpnt1 bisphosphate nucleotidase 1 436627 4.3 1.6
 2.5
 2.4
 4.1
 -0.1
 0.2
 0.5
 0.6
 -0.0
49 ugt5b1 UDP glucuronosyltransferase 5 family, polypeptide B1 100415791 4.3 2.3
1.7
1.1
 1.5
1.5
 4.5
4.3
 6.2
6.0
 2.3
2.0
 5.2
5.1
 2.3
0.4
50 ugt5b4 UDP glucuronosyltransferase 5 family, polypeptide B4 791210 4.3 2.3
1.7
1.1
 1.5
1.5
 4.5
4.3
 6.2
6.0
 2.3
2.0
 5.2
5.1
 2.3
0.4
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