Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3  aplp1  amyloid beta (A4) precursor-like protein 1 
 dre-r.3  aplp1  amyloid beta (A4) precursor-like protein 1 
 dre-m.5  aplp1  amyloid beta (A4) precursor-like protein 1 
 dre-u.3  appa  amyloid beta (A4) precursor protein a 
 dre-u.3  aplp2  amyloid beta (A4) precursor-like protein 2 
 dre-u.3  appb  amyloid beta (A4) precursor protein b 
 hsa-u.4  APP  amyloid beta precursor protein 
 hsa-u.4  APLP1  amyloid beta precursor like protein 1 
 hsa-u.4  APLP2  amyloid beta precursor like protein 2 
 mmu-u.4  App  amyloid beta (A4) precursor protein 
 mmu-u.4  Aplp2  amyloid beta (A4) precursor-like protein 2 
 mmu-u.4  Aplp1  amyloid beta (A4) precursor-like protein 1 
 rno-u.3  Aplp2  amyloid beta precursor like protein 2 
 rno-u.3  Aplp1  amyloid beta precursor like protein 1 
 rno-u.3  App  amyloid beta precursor protein 
 gga-u.3  APP  amyloid beta precursor protein 
 gga-u.3  APLP2  amyloid beta precursor like protein 2 
 mcc-u.3  APP  amyloid beta precursor protein 
 mcc-u.3  APLP1  amyloid beta precursor like protein 1 
 mcc-u.3  APLP2  amyloid beta precursor like protein 2 
 cfa-u.3  APLP1  amyloid beta precursor like protein 1 
 cfa-u.3  APP  amyloid beta precursor protein 
 cfa-u.3  APLP2  amyloid beta precursor like protein 2 
 dme-u.3  Appl  beta amyloid protein precursor-like 
 cel-u.3  apl-1  Amyloid-beta-like protein 

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Top 50 coexpressed genes to aplp1 (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre30   Pentose phosphate pathway  1 33 -
 dre52   Galactose metabolism  1 34 -
 dre62   Fatty acid elongation  1 42 -
 dre10   Glycolysis / Gluconeogenesis  1 81 -
 dre230   Purine metabolism  1 165 -

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dre:aplp1 (amyloid beta (A4) precursor-like protein 1) External Links;


Show/Hide Columns:        
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID
Other ID LINK Target Reference

dre-u.3
for
aplp1


dre-r.3
for
aplp1


dre-m.5
for
aplp1


dre-u.3
for
appa


dre-u.3
for
aplp2


dre-u.3
for
appb


hsa-u.4
for
APP


hsa-u.4
for
APLP1


hsa-u.4
for
APLP2


mmu-u.4
for
App


mmu-u.4
for
Aplp2


mmu-u.4
for
Aplp1


rno-u.3
for
Aplp2


rno-u.3
for
Aplp1


rno-u.3
for
App


gga-u.3
for
APP


gga-u.3
for
APLP2


mcc-u.3
for
APP


mcc-u.3
for
APLP1


mcc-u.3
for
APLP2


cfa-u.3
for
APLP1


cfa-u.3
for
APP


cfa-u.3
for
APLP2


dme-u.3
for
Appl


cel-u.3
for
apl-1

1 spock3 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 562002 5.7 3.0

3.1
3.0
2.7
1.6
4.5
3.6
1.4
1.2
1.6
1.4
1.6
0.7
2.0
1.5
1.9
0.3
4.5
2.5
2.4
0.4
2.7
1.5
2.6
1.8
2.3
1.7
1.4
1.4
0.9
0.4
1.1
-0.9
2.2
1.4
1.2
0.5
1.1
0.5
0.8
-0.4
5.5
0.5
2 si:dkey-178k16.1 si:dkey-178k16.1 569390 5.2 2.7

1.7
1.0
1.6
-1.0
3.1
0.6
3.4
-0.4
2.3
0.9
3.1
-0.3
1.0
0.2
1.6
-0.2
0.5
2.9
-0.8
0.7
-0.1
0.3
1.2


3 scn2b sodium channel, voltage-gated, type II, beta 777666 5.1 2.7

3.7
1.0
0.3
0.8
0.2
0.4
1.0
-0.0
0.9
1.6
0.4
1.7


1.4
1.3
2.2
-0.8
-1.0
0.5


4 spock2 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2 100320541 5.0 2.6

3.1
3.0
2.7
1.6
4.5
3.6
1.4
1.2
1.6
1.4
1.6
0.7
2.0
1.5
1.9
0.3
4.5
2.5
2.4
0.4
2.7
1.5
2.6
1.8
2.3
1.7
1.4
1.4
0.9
0.4
1.1
-0.9
2.2
1.4
1.2
0.5
1.1
0.5
0.8
-0.4
5.5
0.5
5 dpp6b dipeptidyl-peptidase 6b 566832 4.9 2.6

0.8
0.4
0.1
0.1
2.3
0.3
1.3
0.3
0.9
0.4
1.1
-0.2
0.5
0.2
0.6
-0.1
2.2
0.5
1.1
0.4
1.4
0.4
1.5
1.2
1.1
1.1
1.2
1.2
1.5
1.2
0.2
-0.2
2.0
1.5
0.7
0.5
1.0
0.6
0.5
-0.3
3.1
1.5
2.2
1.5
6 ywhag1 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1 117604 4.9 3.1
1.4
3.1
2.4
2.4
2.1
3.2
2.8
2.3
2.2
1.4
1.0
1.8
1.5
2.1
1.2
3.1
3.0
2.0
1.0
3.3
2.6
1.9
1.7
3.2
2.8
4.1
3.5
4.4
2.5
3.4
3.0
0.9
0.8
2.9
2.7
1.1
0.8
1.5
1.5
1.4
1.4
4.8
0.5
4.4
-0.1
7 rac3b Rac family small GTPase 3b 795167 4.8 2.3
2.1
1.8
0.6
1.0
1.0
4.0
3.0
1.5
0.4
2.2
0.1
3.3
0.3
1.3
1.1
2.5
0.1
1.2
0.6
2.6
0.4
0.7
0.7
2.3
0.1
2.0
1.3
1.4
0.1
1.2
-0.2
2.1
0.6
3.2
-0.3
2.9
0.2
2.2
0.5
1.2
-0.3
0.4
0.2
1.0
0.1
8 edil3a EGF-like repeats and discoidin I-like domains 3a 793444 4.8 2.5

2.5
1.4
2.9
0.6
5.5
0.4
1.3
0.8
-0.3
2.0
0.6
2.4
-0.4
1.9
1.4
1.5
1.8
0.4
2.0
0.4
0.7
1.0
1.4


9 sptbn4a spectrin, beta, non-erythrocytic 4a 100003123 4.7 2.5























10 nrxn3b neurexin 3b 570698 4.6 2.4

1.9
0.5
1.0
0.7
1.9
1.3
-0.3
2.1
-0.3
0.7
0.5
0.4
0.3
2.8
0.7
0.8
0.2
0.6
-0.1
1.5
0.9
1.1
1.0
0.4
0.0
1.0
0.4
0.9
0.2



5.9

11 si:ch211-288d18.1 si:ch211-288d18.1 558401 4.6 2.4

3.0
0.9
2.0
1.6
1.3
1.1



0.0
1.0
-1.6
-0.1
-0.1
0.8
1.2
-1.6
2.1
-0.3
0.4
0.5
-0.7
0.1
0.6
0.2
-1.7

12 clip3 CAP-GLY domain containing linker protein 3 562450 4.6 2.4

2.0
-0.5
1.7
-0.6
2.1
0.3
0.6
0.4
4.0
-0.6
-0.4
-1.0
0.4
-0.3
1.0
-1.5
5.8
-0.7
0.4
-1.0
1.6
-0.9
2.3
-0.3
0.6
-0.3
0.4
-2.0
2.1
-0.2
-1.6
-2.6
3.4
-0.4
-1.1
-2.2
-0.9
-1.3


13 cplx2l complexin 2, like 436732 4.5 1.9
2.3
3.1
2.0
0.6
0.3
2.9
2.5
0.5
-0.8
2.0
2.0
-0.3
-0.7
-0.3
0.9
2.8
1.9
1.1
1.5
1.2
1.3
1.0
2.2
1.4
1.3
-0.5
0.1
-0.8
0.3
0.2
-0.0
-0.5
0.1
-0.1
0.4
-0.2
0.5
0.0


14 elavl4 ELAV like neuron-specific RNA binding protein 4 30737 4.5 2.7
1.5
2.2
2.1
0.8
0.2
1.7
0.5
1.5
0.9
3.9
1.3
0.1
-0.0
0.2
-0.5
0.8
0.1
3.9
1.2
0.8
-0.0
1.1
0.3
0.8
0.3
1.0
0.6
0.5
0.5
0.2
-0.2
1.6
0.6
0.6
-0.1
1.6
0.3
0.3
0.0
0.6
-0.2
9.3
4.7
1.8
15 kif1ab kinesin family member 1Ab 566766 4.4 2.3

1.8
1.7
2.0
1.7
4.9
3.0
1.5
0.6
4.3
0.9
0.9
0.3
3.9
2.0
3.0
1.2
3.5
0.1
1.3
0.3
4.0
0.5
1.8
0.1
2.4
0.8
1.2
-0.1
1.1
-0.4
1.7
0.4
0.6
0.5
0.7
0.2
1.0
0.9
1.6
1.2
6.5
1.5
16 LOC110439786 uncharacterized LOC110439786 110439786 4.4 2.3























17 syn1 synapsin I 570672 4.4 1.7
2.4
2.6
1.0
0.4
0.3
2.0
2.0
0.6
0.3
2.8
1.0
0.5
-0.1
1.3
0.9
1.5
0.5
5.9
2.0
0.9
0.8
2.5
1.6
1.8
1.4
1.1
0.0
0.8
0.2
1.2
-0.6
0.3
-0.0
1.3
0.9
0.9
-0.7
-0.0
-0.1
0.7
0.3
9.7
0.8
18 snap25a synaptosome associated protein 25a 30712 4.4 2.6
1.5
0.8
0.3
0.5
0.3
2.6
1.0
1.3
0.5
4.0
-1.1
0.8
-0.7
0.5
-1.3
1.0
0.6
2.5
-0.8
1.7
-2.2
1.1
-1.0
1.1
-0.3
0.4
-0.1
0.9
-0.6
1.1
0.3
-0.1
-0.5
0.4
-0.2
2.0
-0.2
-0.1
-0.5
1.0
-1.5
4.6
-0.4
2.3
-0.1
19 robo2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 60309 4.4 2.3
1.8
1.5
1.2
1.3
1.1
2.4
0.8
0.7
0.3
1.1
1.0
0.3
0.2
1.4
-0.3
0.8
1.0
1.7
2.0
1.6
-0.1
-0.6
-0.7
1.7
-0.6
2.1
-0.7
0.4
-0.7
1.9
0.8
-0.3
-0.5
0.2
-1.1
2.9
1.3
2.5
20 sv2a synaptic vesicle glycoprotein 2A 568033 4.2 2.2

2.8
1.2
0.9
0.7
3.7
3.1
1.1
0.8
2.0
-0.7
0.3
-0.2
0.4
0.4
0.1
-0.3
4.8
0.8
1.3
0.7
4.2
0.6
1.8
0.9
1.1
1.0
0.5
-0.1
0.5
-0.2
1.0
0.8
1.6
1.2
0.8
0.1
0.5
-0.9
-0.4
-0.8
2.3
0.9

21 gpm6ab glycoprotein M6Ab 407734 4.2 3.0
0.9
2.8
0.6
1.2
0.1
4.0
2.4
0.9
0.6
1.5
0.7
0.4
-1.0
1.3
1.2
1.3
0.4
2.1
1.5
1.2
0.2
1.4
0.7
1.6
1.6
0.9
-0.0
-0.2
1.4
-0.5
1.9
1.1
0.8
0.1
1.4
0.8
1.0
0.3
0.3
-0.9
-0.3
-0.5
22 dpysl3 dihydropyrimidinase like 3 553166 4.2 1.9
2.1
2.6
1.7
2.3
1.7
5.2
3.2
3.1
1.5
5.5
5.2
2.6
0.4
1.8
1.5
0.7
0.3
5.3
2.1
1.7
1.0
2.9
2.1
4.0
0.5
3.2
1.9
2.2
1.5
3.6
2.0
2.1
1.1
1.7
1.6
1.8
1.5
2.1
1.9
1.5
0.3
2.4
0.8
0.8
23 pcdh1g9 protocadherin 1 gamma 9 553997 4.2 2.2

3.4
1.9
0.8
0.2
2.9
0.7
1.8
1.4
0.9
0.9
0.7
0.6
2.7
2.5
0.8
0.6
1.4
1.3
0.6
0.5
0.5
0.5
2.2
1.9
4.4
1.2
2.0
1.0
1.4
1.3
2.0
1.1
1.4
1.2
-0.3
1.3
-2.1


24 brinp2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 561009 4.2 2.2























25 pcdh7a protocadherin 7a 568198 4.1 2.2























26 LOC100330186 coiled-coil domain-containing protein 136-like 100330186 4.1 2.2

3.1
0.4
3.1
2.1
3.8
1.0



-0.4
0.7
2.4
-0.0
1.0
0.7


1.0
-0.3
0.4
0.3
0.8
-0.4


27 shisa7b shisa family member 7 100034520 4.1 2.2

2.6
0.7
1.1
0.6
1.5
0.5
0.1
-1.4
-0.3
-0.2
0.6
-0.6
0.4
0.5
0.1
0.1
-1.3
-0.5
-0.6
0.5





28 tspan7b tetraspanin 7b 449539 4.1 1.7
2.1
1.0
1.3
2.4
1.4
0.9
0.6
3.1
4.4
1.8
4.4
0.6
3.5
2.9
0.2
0.8
-0.8
0.6
0.2
0.8
2.3


29 basp1 brain abundant, membrane attached signal protein 1 569631 4.1 2.2























30 chrnb2 cholinergic receptor, nicotinic, beta 2 561906 4.1 2.2

1.1
0.3
1.7
-0.1
1.4
1.0
0.2
2.0
-0.9
0.7
-0.2
0.0
-0.5
1.3
1.0
-0.1
-0.9
0.5
0.0
0.7
0.1
-0.0
-1.0
0.3
-0.3
-0.6
1.0
0.7
0.3
-0.1
-0.4
-0.9
0.2
-0.5


31 pcp4b Purkinje cell protein 4b 386963 4.0 2.1

1.2
0.3
1.4
0.9
2.2
1.7
0.6
0.9
-0.1
0.1
-0.7
0.8
-0.1
1.2
-0.0
0.9
-0.9
-0.3
0.4
0.8
0.7
0.6
-0.4


32 cpe carboxypeptidase E 407979 4.0 2.6
1.1
3.9
1.1
2.9
2.4
2.9
2.4
2.2
1.5
3.6
1.2
2.2
1.7
2.0
0.7
2.1
0.2
2.2
2.4
1.7
0.9

4.0
33 elovl6 ELOVL fatty acid elongase 6 317738 4.0 2.1

0.7
-1.2
0.2
-0.9
0.4
-1.1
-0.2
-0.7
1.6
-0.7
0.2
-0.1
-1.1
-1.5
0.4
0.1
-0.7
-1.6
-0.5
-0.2
0.4
2.2
1.2
1.9
0.4
0.8
0.2
0.9
-0.5
0.9
-0.4
-1.8
1.7
0.2
-0.4
34 syngr3b synaptogyrin 3b 570094 4.0 2.1

2.9
2.0
1.7
1.3
1.4
0.6
1.0
-0.1
4.6
1.4
0.5
-0.3
0.0
-0.3
1.8
0.9
4.9
1.4
1.8
1.0
2.1
0.3
1.5
1.0
1.2
-0.6
1.0
0.5
1.1
-0.4
0.7
-0.4
0.5
-0.5
2.9
1.0
0.4
-0.2
0.8
0.8
5.4
1.7
35 ntng2b netrin g2b 101885039 4.0 2.1























36 gnaz guanine nucleotide binding protein (G protein), alpha z polypeptide 564915 4.0 2.1

2.9
2.5
1.6
1.4
3.0
2.8
2.8
2.6
3.2
2.4
3.4
1.8
2.3
1.8
2.0
1.5
4.0
2.0
2.8
2.0
2.3
1.8
4.5
2.8
2.6
2.0
3.3
1.2
2.7
2.0
1.8
1.0
2.4
1.6
1.9
1.4
3.1
1.5
2.3
1.0
4.4
-0.1
2.1
1.6
37 vsnl1a visinin-like 1a 492494 3.9 2.1

1.5
1.5
1.5
0.9
5.1
1.6
1.0
0.6
2.7
2.3
1.6
0.0
3.4
1.2
1.3
1.2
3.6
2.8
2.3
2.0
2.1
2.0
3.0
2.7
2.3
0.7
2.0
0.4
1.2
1.2
1.1
0.8
2.1
2.0
1.7
1.7
2.3
1.4
2.2
1.6
6.5
1.3
0.8
-1.3
38 tmem276b transmembrane protein 276b 559304 3.9 2.1























39 ptprd protein tyrosine phosphatase, receptor type D 100330629 3.9 2.1

3.3
2.7
2.3
1.8
3.7
1.6
2.8
1.6
3.8
1.8
1.4
1.2
1.6
1.5
1.6
1.1
1.4
0.9
2.8
1.1
1.6
1.0
1.3
0.7
2.4
1.9
2.6
1.8
1.3
0.7
1.0
0.1
0.9
0.4
2.3
1.3
3.4
2.2
1.2
0.7

2.8
40 syngr3a synaptogyrin 3a 553617 3.9 2.0

2.9
2.0
1.7
1.3
1.4
0.6
1.0
-0.1
4.6
1.4
0.5
-0.3
0.0
-0.3
1.8
0.9
4.9
1.4
1.8
1.0
2.1
0.3
1.5
1.0
1.2
-0.6
1.0
0.5
1.1
-0.4
0.7
-0.4
0.5
-0.5
2.9
1.0
0.4
-0.2
0.8
0.8
5.4
1.7
41 islr2 immunoglobulin superfamily containing leucine-rich repeat 2 541396 3.8 1.9
1.7
1.0
-0.4
1.0
0.1
1.7
-0.9
0.1
-0.8
0.7
-2.0
0.1
-0.6
0.7
1.1
0.8
0.7
0.0
0.9
-0.9
-0.2


42 rims2a regulating synaptic membrane exocytosis 2a 393672 3.8 2.9
0.7
2.4
0.2
1.9
0.1
1.1
-0.4
-0.2
0.3
1.5
0.2
1.1
0.2
0.8
1.0
0.3
-0.6
1.2





43 adam23a ADAM metallopeptidase domain 23a 794175 3.8 2.0
1.5
1.0
-1.2
0.0
-0.6
1.8
-0.5
0.6
1.1
0.6
0.6
1.1
1.6
1.3
0.8
0.8
0.6
1.0
1.0
1.4
0.9
0.1
-0.1
-1.0


44 doc2b double C2-like domains, beta 100006713 3.8 2.0

3.2
2.0
3.5
2.2
2.6
2.6
1.7
1.2
4.0
3.8
1.4
0.4
0.6
0.5
1.7
1.6
5.6
4.5
1.9
1.7
4.0
3.9
2.7
2.0
1.4
1.2
1.7
1.1
2.0
1.1
3.0
2.1
1.8
1.3
3.3
2.7
1.8
1.0
0.5
0.5
9.7
8.7
3.4
2.8
45 fam171b family with sequence similarity 171 member B 561242 3.8 2.1
1.5
0.1
-1.4
3.4
1.8
1.8
-0.4
0.1
-0.2
2.2
1.8
3.0
1.5
0.7
0.9
0.5
1.0
0.3
1.1
0.5
-0.6


46 pgm2 phosphoglucomutase 2 405822 3.8 2.0

2.0
-0.5
1.3
-0.0
0.9
0.4
1.5
-0.2
0.9
-1.2
1.1
0.3
0.2
-0.2
1.1
0.2
1.1
-0.5
1.0
-0.0
0.3
0.2
0.8
0.1
2.6
0.7
1.7
-1.0
0.9
0.5
1.8
-0.3
0.9
-0.2
-0.6
-1.0
-0.5
-1.2
3.7
1.0
-0.2
-1.0
0.1
47 rhobtb4 Rho related BTB domain containing 4 553415 3.8 2.0

2.1
-0.1
1.6
1.3
2.6
1.4
1.7
-0.7
0.3
-0.4
0.4
-1.1
-0.5
-0.5
-0.9
-1.0
-0.1
-0.9
0.9
-1.2
0.2
-0.7
0.7
0.3
1.1
0.8
1.7
0.8
2.1
-0.8
0.9
0.7
0.2
-1.9
0.4
-1.0
0.9
0.4
-0.0
-1.4
-1.4

48 appb amyloid beta (A4) precursor protein b 170846 3.8 1.8
1.7
4.0
2.6
4.0
2.8
3.8
2.8
6.2
0.2
1.0
0.2
6.2
1.0
5.3
1.7
5.3
1.6
1.7
1.6
6.2
2.0
2.3
2.0
6.2
2.3
4.4
4.4
7.5
-1.5
-0.9
-1.5
7.5
-0.9
1.9
-0.2
2.3
1.9
2.3
-0.2


49 nell2a neural EGFL like 2a 790930 3.7 2.1
1.4
1.2
0.5
0.5
-0.2
2.2
1.7
0.4
0.1
0.8
0.0
0.4
0.1
0.7
0.4
0.1
-1.3
1.7
0.6
0.7
0.4
2.1
-0.6
0.6
0.2
2.3
1.2
0.8
-0.6
0.8
0.6
1.0
0.7
1.1
1.0
2.4
0.2
0.2
-0.2
0.3
-0.5
0.9

50 ndrg4 NDRG family member 4 692305 3.7 2.1
1.3
3.4
1.3
2.1
2.0
4.9
3.6
1.4
1.3
3.1
0.9
2.4
1.9
1.9
0.8
2.7
1.2
4.3
1.4
1.1
1.0
2.0
1.8
2.4
1.7
2.8
1.7
2.3
0.8
1.3
1.1
0.7
0.6
2.3
1.9
1.9
1.6
2.2
1.8
2.1
1.9
1.6
2.2
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