Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3   plk4   polo-like kinase 4 (Drosophila) 
 dre-r.3   plk4   polo-like kinase 4 (Drosophila) 
 dre-m.5   plk4   polo-like kinase 4 (Drosophila) 
 hsa-u.4   PLK4   polo like kinase 4 
 mmu-u.4   Plk4   polo like kinase 4 
 rno-u.3   Plk4   polo-like kinase 4 
 gga-u.3   PLK4   polo like kinase 4 
 mcc-u.3   PLK4   polo like kinase 4 
 cfa-u.3   PLK4   polo like kinase 4 
 dme-u.3   SAK   Sak kinase 

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Top 50 coexpressed genes to plk4 (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre4110   Cell cycle  8 153 7.04
 dre4914   Progesterone-mediated oocyte maturation  6 106 6.64
 dre4114   Oocyte meiosis  6 145 5.84
 dre3440   Homologous recombination  2 37 2.43
 dre4218   Cellular senescence  3 200 -

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dre:plk4 (polo-like kinase 4 (Drosophila)) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dre-u.3
for
plk4
dre-r.3
for
plk4
dre-m.5
for
plk4
hsa-u.4
for
PLK4
mmu-u.4
for
Plk4
rno-u.3
for
Plk4
gga-u.3
for
PLK4
mcc-u.3
for
PLK4
cfa-u.3
for
PLK4
dme-u.3
for
SAK
1 knl1 kinetochore scaffold 1 327226 8.7 4.9
 3.1
 10.1
 8.0
 9.2
 6.5
 5.2
 10.5
2 aurkb aurora kinase B 791894 8.5 4.4
5.7
4.8
 6.5
6.0
 5.6
4.7
 7.6
 4.1
3.3
 5.9
5.2
 2.7
1.2
3 bub1 BUB1 mitotic checkpoint serine/threonine kinase 100307076 8.2 4.3
9.1
 7.6
 9.2
 7.3
 5.4
 8.8
 1.5
0.5
4 cenpi centromere protein I 558570 8.2 4.3
7.3
 8.0
 8.8
 9.6
 3.0
 6.9
5 cenpl centromere protein L 445401 8.0 4.2
5.4
 7.0
 2.6
 7.8
 5.6
 4.5
6 kifc1 kinesin family member C1 30453 8.0 4.2
11.5
6.0
 10.1
4.6
 7.1
5.7
 6.9
2.4
 4.4
4.3
 7.4
6.8
 4.1
1.9
7 incenp inner centromere protein 572121 7.8 4.3
 2.8
 3.4
 7.8
 3.2
 8.0
 2.6
 3.3
8 anln anillin, actin binding protein 562517 7.7 4.0
9.8
 7.1
 5.3
 7.1
 3.5
 6.6
 1.0
9 pbk PDZ binding kinase 360218 7.6 4.0
7.8
 6.4
 6.9
 7.8
 4.6
 8.2
 1.3
10 foxm1 forkhead box M1 394072 7.5 3.8
 3.1
 6.1
 7.1
 6.9
 8.0
-0.9
 5.3
 6.0
11 cenpe centromere protein E 767754 7.5 4.0
 2.9
 11.5
6.0
 10.1
4.6
 7.1
5.7
 6.9
2.4
 4.4
4.3
 7.4
6.8
 4.1
1.9
12 kif18a kinesin family member 18A 393209 7.4 4.4
 2.4
 10.5
4.4
 9.5
5.0
 8.4
7.3
 9.4
5.9
 4.8
3.6
 5.4
5.1
 4.0
-0.4
13 cenpt centromere protein T 562197 7.3 4.7
 2.0
 0.7
 2.3
 4.4
 8.2
 1.3
 7.1
14 ncapd2 non-SMC condensin I complex, subunit D2 552978 7.3 3.8
2.5
 5.7
 6.1
 5.7
 4.3
 5.6
 1.8
15 ska3 spindle and kinetochore associated complex subunit 3 570479 7.3 3.8
9.2
 7.0
 5.0
 8.3
 4.4
 6.7
16 blm BLM RecQ like helicase 572540 7.1 3.7
6.7
1.4
 7.6
2.1
 4.7
1.6
 6.0
1.0
 2.8
2.3
 1.7
0.2
 3.2
17 tpx2 TPX2 microtubule nucleation factor 107966129 7.1 3.7
7.6
 6.8
 5.0
 9.9
 4.7
 8.2
18 cdca8 cell division cycle associated 8 492815 7.0 4.7
 1.7
 7.0
 7.6
 7.3
5.4
 6.6
19 nuf2 UF2 component of NDC80 kinetochore complex 393280 7.0 4.6
 1.9
 11.1
 7.8
 9.6
 9.8
 4.8
 9.0
20 cdk1 cyclin-dependent kinase 1 80973 7.0 4.8
 1.6
 9.0
2.8
 6.1
2.5
 7.5
3.7
 9.2
5.4
 6.3
0.7
 5.3
2.1
 1.2
1.1
21 arhgap19 Rho GTPase activating protein 19 100537002 7.0 3.7
2.5
 4.0
 2.9
 6.7
 3.9
 4.0
 1.7
22 smc4 structural maintenance of chromosomes 4 192332 7.0 3.3
 3.1
 6.5
 7.9
 6.3
 6.9
 5.3
 5.7
 0.9
23 fbxo5 F-box protein 5 445392 6.9 4.3
 2.1
 7.7
 7.8
 4.6
 2.3
 4.7
 6.4
24 rad54l RAD54 like 394119 6.9 3.7
 2.6
 5.1
 4.3
 4.3
 5.2
 3.0
 6.3
 2.8
25 si:ch211-63o20.7 si:ch211-63o20.7 566836 6.9 3.6







26 haus1 HAUS augmin-like complex, subunit 1 553389 6.9 3.6
2.1
 3.0
 2.7
 5.1
 2.9
 2.8
27 kif2c kinesin family member 2C 100136875 6.9 4.4
 1.9






28 nusap1 nucleolar and spindle associated protein 1 567446 6.9 3.9
 2.4
 8.1
 7.7
 6.8
 10.5
 4.2

29 hmmr hyaluronan-mediated motility receptor (RHAMM) 322012 6.9 3.6
8.1
 7.3
 6.7
 7.1
 5.1
 5.0
30 dlgap5 discs, large (Drosophila) homolog-associated protein 5 447853 6.9 3.6
 2.6
 8.7
 5.6
 6.6
 8.2
 4.1
 8.7
 3.3
31 ttk ttk protein kinase 317763 6.8 3.8
 2.4
 13.8
 8.2
 8.0
 10.1
 6.9
 11.8
 1.9
32 ndc80 NDC80 kinetochore complex component 445386 6.8 4.4
 1.9
 10.2
 7.1
 7.6
 8.4
 5.5
 9.4
33 cenpj centromere protein J 568957 6.8 3.5
 2.7
 5.3
 4.0
 1.3
 7.7
 2.3
 3.9
 1.9
34 chaf1a chromatin assembly factor 1, subunit A (p150) 563212 6.8 3.5
5.2
 6.4
 5.5
 4.5
 4.1
 5.1
 -0.2
35 sgo1 shugoshin 1 791138 6.8 3.6
 2.6
 8.3
 8.4
 7.1
 8.8
 4.6
 9.5
36 ube2c ubiquitin-conjugating enzyme E2C 566441 6.7 3.5
5.2
 5.2
 5.6
 6.8
5.3
 2.7
37 plk1 polo-like kinase 1 (Drosophila) 280649 6.7 3.8
 2.4
 5.7
0.5
 5.9
-0.2
 5.4
0.6
 8.5
0.4
 3.6
-0.1
 7.3
-0.1
 2.2
38 kif11 kinesin family member 11 195818 6.6 3.7
 2.4
 11.9
 9.8
 8.4
 8.8
 6.6
 9.6
 1.3
39 dbf4 DBF4 zinc finger 799015 6.6 3.4
6.2
1.0
 8.9
 7.4
 3.4
2.8
 3.8
0.5
 4.4
2.8
 0.7
40 ncaph non-SMC condensin I complex, subunit H 570062 6.6 3.5
 2.5
 9.4
 7.5
9.1
 3.9
 6.9
 5.2
41 haspin histone H3 associated protein kinase 557879 6.5 3.9
 2.1
 6.1
 6.2
 5.7
 8.7
 3.4
 4.7
 1.7
42 ccnb3 cyclin B3 767751 6.5 4.1
 1.9
 6.6
6.0
 6.7
6.0
 6.7
5.3
 6.9
6.7
 4.4
3.0
 8.6
7.0
 0.9
0.8
43 kif14 kinesin family member 14 562052 6.5 3.9
 2.1
 8.8
 4.0
 6.1
 4.6
 4.6
 7.0
 3.5
44 cdc7 cell division cycle 7 homolog (S. cerevisiae) 492768 6.5 3.6
 2.4
 6.5
 5.1
 2.8
 8.2
 2.4
 2.4
 0.4
-0.8
45 top2a DNA topoisomerase II alpha 323733 6.5 4.6
 1.4
 9.0
0.5
 6.9
0.7
 7.8
-0.6
 9.4
1.1
 5.8
1.8
 9.4
0.6
 0.4
46 spdl1 spindle apparatus coiled-coil protein 1 568360 6.5 3.6
 2.3
 4.4
 9.4
 6.3
 4.2
 4.0
 4.8
47 melk maternal embryonic leucine zipper kinase 30724 6.4 3.8
 2.2
 9.2
 6.3
 6.2
 7.4
 4.3
 5.2
48 cdc25b cell division cycle 25B 57925 6.4 3.2
 2.7
 5.3
5.1
 4.9
3.2
 3.1
1.2
 2.1
 3.4
1.6
 4.2
3.6
 4.1
0.1
49 ckap2l cytoskeleton associated protein 2-like 569937 6.4 4.0
 1.8
 9.7
 8.2
 8.5
 2.0
 5.3
 7.3
50 aurka aurora kinase A 445246

5.7
4.8
 6.5
6.0
 5.6
4.7
 7.6
 4.1
3.3
 5.9
5.2
 2.7
1.2
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