Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3   arhgef1a   Rho guanine nucleotide exchange factor (GEF) 1a 
 dre-r.3   arhgef1a   Rho guanine nucleotide exchange factor (GEF) 1a 
 dre-u.3   101884284   rho guanine nucleotide exchange factor 28-like 
 dre-u.3   arhgef2   rho/rac guanine nucleotide exchange factor (GEF) 2 
 hsa-u.4   ARHGEF2   Rho/Rac guanine nucleotide exchange factor 2 
 mmu-u.4   Arhgef2   rho/rac guanine nucleotide exchange factor (GEF) 2 
 rno-u.3   Arhgef2   Rho/Rac guanine nucleotide exchange factor 2 
 gga-u.3   ARHGEF2   Rho/Rac guanine nucleotide exchange factor 2 
 mcc-u.3   ARHGEF2   Rho/Rac guanine nucleotide exchange factor 2 
 cfa-u.3   ARHGEF2   Rho/Rac guanine nucleotide exchange factor 2 
 dme-u.3   cyst   cysts 
 spo-u.3   orc4   origin recognition complex subunit Orc4 

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Top 50 coexpressed genes to arhgef1a (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre4144   Endocytosis  5 324 2.93
 dre4012   ErbB signaling pathway  4 104 3.91
 dre600   Sphingolipid metabolism  2 61 2.01
 dre4810   Regulation of actin cytoskeleton  3 308 -
 dre4010   MAPK signaling pathway  3 409 -

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dre:arhgef1a (Rho guanine nucleotide exchange factor (GEF) 1a) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dre-u.3
for
arhgef1a
dre-r.3
for
arhgef1a
dre-u.3
for
101884284
dre-u.3
for
arhgef2
hsa-u.4
for
ARHGEF2
mmu-u.4
for
Arhgef2
rno-u.3
for
Arhgef2
gga-u.3
for
ARHGEF2
mcc-u.3
for
ARHGEF2
cfa-u.3
for
ARHGEF2
dme-u.3
for
cyst
spo-u.3
for
orc4
1 nav1a neuron navigator 1a 100536287 5.7 3.0
 0.3
0.3
 3.7
1.5
 2.9
1.0
 1.5
0.7
 2.8
0.6
 4.2
1.2
 2.4
-0.1
 1.3
1.2
 0.4
2 LOC103909207 uncharacterized LOC103909207 103909207 5.6 2.9









3 shc1 SHC (Src homology 2 domain containing) transforming protein 1 323818 5.1 2.7
 0.3
0.1
 1.9
0.2
 2.6
0.3
 1.6
1.4
 1.6
1.3
 1.7
0.6
 1.1
-0.2
 1.8
0.7
 1.7
4 prdm1a PR domain containing 1a, with ZNF domain 323473 5.1 2.7
 -0.2
-0.9
 2.8
2.3
 0.7
 0.8
 0.9
 1.1
 0.3
 0.5
 -0.1
5 slc7a3b solute carrier family 7 member 3b 100003376 4.8 2.5
 0.7
0.3
 1.7
1.1
 2.8
0.4
 1.8
0.9
 2.8
0.8
 1.5
1.4
 0.6
0.0
 1.8
1.0
 1.2
0.8
6 wipf3 WAS/WASL interacting protein family member 3 368364 4.6 2.4
 0.0
 0.4
 -1.0
 0.3
 1.3
 -0.9
 0.4
 0.1

7 spag1a sperm associated antigen 1a 564953 4.5 2.4
 0.2
0.2
 0.9
-0.1
 0.5
-1.2
 -0.1
-1.5
 0.1
-0.8
 -0.8
-1.6
 0.6
-1.8
 2.3
-0.9
 -0.3
 0.6
-0.8
8 sgpp1a sphingosine-1-phosphate phosphatase 1a 556439 4.5 2.4
 0.3
-0.0
 2.2
2.0
 -0.3
-0.6
 -3.4
 -0.2
-1.4
 2.0
-1.4
 0.8
0.4
 0.7
-2.1
-1.5
9 abca1b ATP-binding cassette, sub-family A (ABC1), member 1B 100136868 4.4 2.3
 1.2
0.5
 2.1
1.5
 1.1
0.8
 0.7
-0.1
 1.5
0.0
 1.2
0.4
 2.0
1.1
 0.2
-0.5

10 tmem108 transmembrane protein 108 563089 4.4 2.3
 -0.1
 -0.5
 0.3
 -0.7
 1.2
 0.1
 -0.0
 0.7

11 skia v-ski avian sarcoma viral oncogene homolog a 30101 4.3 2.3
 -0.4
-0.8
 0.9
-1.9
 0.9
 1.1
 0.8
 -0.8
 2.2
 1.3
 -0.5
12 grk4 G protein-coupled receptor kinase 4 560761 4.3 2.3
 0.4
0.1
 2.3
0.2
 1.4
1.2
 0.7
0.5
 0.9
-0.0
 2.2
1.3
 2.0
0.2
 2.9
1.5
 1.3
 1.0
13 abi1a abl-interactor 1a 393711 4.2 2.2
 1.0
0.5
 3.0
0.7
 0.5
-0.2
 2.6
0.7
 2.4
1.3
 0.5
0.3
 0.3
-0.8
 1.0
0.5
 1.5
14 arpc5a actin related protein 2/3 complex, subunit 5A 336504 4.2 2.2
 -0.3
-0.4
 2.3
0.1
 1.6
-0.3
 0.4
-0.3
 -0.1
-0.2
 0.9
-1.8
 2.5
0.4
 1.8
-0.7
 -1.3
 -0.5
15 arid5b AT-rich interaction domain 5B 100536827 4.1 2.2
 1.0
 0.5
 -0.5
 -0.2
 0.5
 -1.0
 -0.6
 0.0

16 cdkn1ba cyclin-dependent kinase inhibitor 1Ba 402862 4.1 2.2
 0.3
-0.8
 0.8
-0.2
 1.4
 0.5
 0.1
 -0.9
 -0.2
 -0.7

17 tiam1b TIAM Rac1 associated GEF 1b 100330358 4.1 2.2
 0.8
-0.2
 3.1
0.4
 1.3
0.8
 -0.4
 2.4
0.1
 1.6
0.8
 1.5
-0.3
 1.4
0.0

18 mrasb muscle RAS oncogene homolog b 100317924 4.1 2.2
 0.5
-0.0
 1.5
-0.2
 0.8
 0.3
 1.9
 1.6
 2.3
 -0.1
0.1
19 ubtd2 ubiquitin domain containing 2 436991 4.0 2.1
 1.4
-0.2
 2.3
0.0
 1.5
0.2
 1.3
0.6
 0.1
 1.2
-0.9
 1.5
-0.6
 2.3
0.5
 -0.3
 0.9
20 si:dkey-118j18.2 si:dkey-118j18.2 100331646 3.9 2.1









21 st6galnac ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 407706 3.9 2.1
 -0.8
 0.8


1.1



22 fosl2 FOS like 2, AP-1 transcription factor subunit 558921 3.9 2.1
 0.7
 0.4
 0.1
 0.6
 0.1
 1.1
 -0.5
 1.4

23 fmnl3 formin-like 3 407694 3.9 2.1
 1.6
0.9
 2.7
2.2
 4.0
3.5
 3.5
2.8
 3.1
3.0
 3.1
2.7
 3.2
2.5
 3.8
1.3
 -0.6
24 slc30a1a solute carrier family 30 member 1a 393853 3.9 2.1
 0.9
0.6
 1.0
0.4
 -0.2
-0.7
 -0.4
-1.5
 -0.7
-1.3
 -0.7
-1.7
 0.2
-1.4
 -0.4
-1.2
 0.0
 -1.5
25 tagln2 transgelin 2 259183 3.9 2.1
 1.4
1.2
 1.3
0.5
 1.8
1.0
 1.9
1.5
 3.1
1.6
 2.1
0.2
 2.2
1.7
 3.3
1.5
 -0.5
-1.0
 -0.4
26 LOC101882826 complement component C1q receptor 101882826 3.9 2.1
 -0.8
 0.3
 0.8
 1.4
 0.8
 1.9
 0.9
 -0.1

27 egfra epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) 378478 3.9 2.0
 0.7
0.6
 1.1
0.5
 -0.4
-0.5
 0.6
-0.0
 0.4
-0.3
 0.9
0.2
 -0.4
-0.9
 0.3
0.0
 -0.1
28 nck1b NCK adaptor protein 1b 100334953 3.8 2.0
 0.2
0.1
 0.2
-0.1
 0.8
0.5
 3.1
0.5
 2.0
-0.5
 0.4
 0.2
0.1
 2.9
0.1
 1.8
29 plxdc2b plexin domain containing 2b 100000303 3.8 2.0
 1.1
0.6
 0.3
-0.7
 -0.1
-0.8
 1.0
0.3
 1.4
0.9
 0.5
-0.7
 0.9
0.6
 -0.8
-1.3
 2.1
30 rin2a Ras and Rab interactor 2a 100006622 3.8 2.0
 2.5
1.3
 1.2
0.8
 1.5
0.6
 3.6
1.7
 1.4
0.6
 0.1
-0.9
 2.9
-0.2
 1.8
1.0
 2.1
31 kalrnb kalirin RhoGEF kinase b 678652 3.8 2.0
 1.0
1.0
 1.6
0.8
 0.7
 2.3
 2.3
1.5
 -0.4
 1.2
 1.0
 1.9
32 pld1b phospholipase D1b 572492 3.8 2.0
 3.1
0.4
 -0.1
-0.1
 0.4
-0.3
 1.2
1.0
 1.5
0.4
 0.8
 1.4
 1.2
0.3
 1.2
 -2.3
33 kbtbd11 kelch repeat and BTB domain containing 11 557467 3.8 2.0
 0.3
 0.4
 0.7
 1.1
 -0.1
 1.1
 0.1
 0.1

34 mpp1 membrane palmitoylated protein 1 325542 3.8 2.0
 0.0
 1.2
 -0.0
 -0.8
 0.2
 -0.6
 -0.2
 1.2

35 fam171a2a family with sequence similarity 171 member A2a 556398 3.8 2.0
 0.3
-0.3
 0.7
-1.4
 0.1
 1.7
 0.8
 4.7
 0.6
 1.2

36 sfmbt2 Scm like with four mbt domains 2 555450 3.8 2.0
 -0.4
 1.1
 -0.5
0.9
 -0.2
 -1.9
 -0.4

37 timp2b TIMP metallopeptidase inhibitor 2b 406650 3.8 2.0
 1.3
0.1
 1.1
0.8
 1.2
0.5
 0.4
 -0.5
-0.8
 1.0
0.4
 1.6
1.0
 0.5
-0.1
 -2.2
 -2.0
38 afap1l2 actin filament associated protein 1-like 2 567369 3.7 2.0
 1.6
 2.2
 0.5
 -0.3
 0.2
 0.7
 -0.3
 -0.2

39 plekho1b pleckstrin homology domain containing, family O member 1b 562940 3.7 2.0
 0.1
 2.7
 2.7
 2.7
 2.2
 2.2
 2.5
 2.5

40 chsy1 chondroitin sulfate synthase 1 324407 3.7 2.0
 0.1
 -0.6
 0.4
 1.1
0.5
 2.5
0.8
 0.7
0.0
 1.1
0.3
 3.0
-0.9
 -0.7
41 rbm47 RNA binding motif protein 47 562991 3.7 2.0
 0.9
 1.9
 -0.5
 -0.5
 -0.5
 -0.7
 0.3
 -0.3

42 cd63 CD63 molecule 321461 3.7 2.0
 -0.0
 1.0
 0.5
 0.7
 -0.5
 0.5
 0.8
 -0.4
 0.5
-0.3
 -1.4
43 gba glucosidase, beta, acid 559072 3.7 2.0
 0.4
 1.1
 1.5
 -0.5
 1.1
 3.3
0.7
 1.3
 0.3
 -0.4
-0.6
44 map3k14a mitogen-activated protein kinase kinase kinase 14a 100004261 3.7 2.0
 0.1
 0.9
 1.4
 2.1
0.6
 2.4
 -0.9

45 bcl6b BCL6B transcription repressor 793278 3.7 2.0
 0.1
 -1.0
 0.7
 0.2
 0.1
0.3
 0.3

46 agfg1b ArfGAP with FG repeats 1b 393560 3.7 1.9
 0.1
-0.3
 0.9
0.2
 1.2
 0.3
 2.3
 -0.4
 1.7
 -0.0
 2.9
 -2.2
47 bend3 BEN domain containing 3 565716 3.6 1.9
 0.1
 0.2
 1.6
 -0.3
 -0.4
 -0.8
 -0.4
 0.5

48 prkar1aa protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) a 494533 3.6 1.9
 1.2
0.4
 1.7
-0.8
 0.6
0.0
 0.9
0.4
 0.3
-1.2
 -0.0
-0.8
 1.3
-0.1
 1.4
0.8
 0.2
49 tgfbr2a transforming growth factor beta receptor 2a 100334928 3.6 1.9
 0.9
0.5
 1.3
1.1
 0.7
-0.7
 0.4
0.2
 0.2
-0.3
 -0.5
-0.8
 -0.1
-1.1
 0.2
-0.2
 1.5
50 triob trio Rho guanine nucleotide exchange factor b 368847 3.6 1.9
 1.0
1.0
 1.6
0.8
 0.7
 2.3
 2.3
1.5
 -0.4
 1.2
 1.0
 1.9
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