Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3   hsd3b7   hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 
 dre-r.3   hsd3b7   hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 
 dre-m.5   hsd3b7   hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 
 dre-u.3   hsd3b2   hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 
 hsa-u.4   HSD3B1   hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 
 hsa-u.4   HSD3B7   hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 
 rno-u.3   Hsd3b3   hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 
 rno-u.3   Hsd3b1   hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 
 gga-u.3   121108723   3 beta-hydroxysteroid dehydrogenase type 7-like 
 gga-u.3   HSD3B1   hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 
 gga-u.3   HSD3B7   hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 
 mcc-u.3   HSD3B7   hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 
 cfa-u.3   HSD3B2   hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 
 cfa-u.3   HSD3B7   hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 
 dme-u.3   CG7724   uncharacterized protein 
 cel-u.3   C32D5.12   3Beta_HSD domain-containing protein 
 spo-u.3   rpl3702   60S ribosomal protein L37 
 spo-u.3   rpl3703   60S ribosomal protein L37 

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Top 50 coexpressed genes to hsd3b7 (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre3320   PPAR signaling pathway  5 84 5.71
 dre120   Primary bile acid biosynthesis  4 21 6.73
 dre140   Steroid hormone biosynthesis  4 53 5.06
 dre230   Purine metabolism  3 156 2.18
 dre240   Pyrimidine metabolism  2 74 -

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dre:hsd3b7 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase) External Links;


Show/Hide Columns:        
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dre-u.3
for
hsd3b7
dre-r.3
for
hsd3b7
dre-m.5
for
hsd3b7
dre-u.3
for
hsd3b2
hsa-u.4
for
HSD3B1
hsa-u.4
for
HSD3B7
rno-u.3
for
Hsd3b3
rno-u.3
for
Hsd3b1
gga-u.3
for
121108723
gga-u.3
for
HSD3B1
gga-u.3
for
HSD3B7
mcc-u.3
for
HSD3B7
cfa-u.3
for
HSD3B2
cfa-u.3
for
HSD3B7
dme-u.3
for
CG7724
cel-u.3
for
C32D5.12
spo-u.3
for
rpl3702
spo-u.3
for
rpl3703
1 bpnt1 bisphosphate nucleotidase 1 436627 5.0 2.5
 2.1
 -1.7
 0.3
 0.2
 0.6
 0.5
 -0.4
 0.9
 1.6
 -0.1
 0.0
 0.4
 1.2
 0.2

2 papss2a 3'-phosphoadenosine 5'-phosphosulfate synthase 2a 777719 4.7 2.5
0.9
0.3
 0.2
-0.7
 0.6
0.3
 -0.0
-0.4
 -0.5
-0.5
 0.7
0.6
 0.5
-1.3
 0.6
-0.1
 0.3
-1.1
 0.4
-0.2
 1.8
0.1
 -0.1
 -0.4
 -2.0
 -1.1
3 cyp8b3 cytochrome P450, family 8, subfamily B, polypeptide 3 447848 4.5 1.9
 2.2
 -0.9
-1.3
 3.0
 0.2
 1.3
 1.7


1.2
 1.3
 0.7



4 sult2st3 sulfotransferase family 2, cytosolic sulfotransferase 3 777792 4.4 2.3
0.2
-0.1
 4.2
2.1
 1.4
0.9
 1.8
1.6
 2.8
2.6
 1.8
1.3
 1.9
0.6
 3.5
3.4
 1.2
1.2
 1.6
0.9
 2.3
1.9
 3.3
1.7
 -0.3

5 zgc:158403 zgc:158403 790939 4.3 2.3
-0.1
-0.9
 -0.8
 -0.1
 0.7
0.1
 0.6
0.5
 1.2
-0.4
 -0.1
-0.3
 1.1
0.6
 1.8
0.1
 0.1
0.0
 1.5
0.8
-0.6

6 srd5a2a steroid-5-alpha-reductase, alpha polypeptide 2a 550398 4.3 1.7
 2.3
 -1.5
 0.5
-0.2
 1.4
0.4
 -0.0
 0.2
 -0.1
-0.7
 0.9
-1.3
 -0.1
-1.5
 0.1
 0.4
 -0.1
0.8
0.7
 -0.4
 0.7
7 si:dkey-91i10.3 si:dkey-91i10.3 565876 4.2 2.2
0.4
0.0
 0.7
0.3
 1.7
1.3
 0.7
 -0.3
 1.5
-0.9
 1.2
-1.1
 1.3
-1.4
 0.9
0.3
 1.4
0.5
 1.4
0.5

6.3
4.1
 7.3
5.8
8 glsb glutaminase b 564746 4.1 2.2
-0.3
-0.6
 0.5
-0.4
 1.0
-0.1
 -0.7
 -1.0
 -0.6
 -0.2
 -1.2
 0.3
0.1
 1.3
-0.8
 1.6
-0.4
 -2.1
 -0.2
-0.8
 3.6
2.6
 3.4
1.7
9 rab11fip4b RAB11 family interacting protein 4 (class II) b 100151129 4.0 2.1
1.0
0.6
 -0.5
 -0.7
 -0.2
-0.6
 -0.4
-0.6
 0.5
0.5
 0.6
0.5
 1.3
0.4
 -0.9
-1.6
 -0.0
-0.4
 -0.3
-0.6
 0.3
 0.6

10 gchfr GTP cyclohydrolase I feedback regulator 393735 4.0 1.3
 2.4
 -1.2
 0.1
 1.9
 -2.6
 -1.0
 0.5
 -0.3
 0.8
 1.0
 0.1
 2.9
1.1

11 cyp8b1 cytochrome P450, family 8, subfamily B, polypeptide 1 445281 3.9 1.4
 2.3
 -0.9
-1.3
 3.0
 0.2
 1.3
 1.7


1.2
 1.3
 0.7



12 deptor DEP domain containing MTOR-interacting protein 768177 3.8 1.4
 2.2
 -1.6
 -0.9
 0.0
 0.4
 -0.5
 -0.8
 0.6
 0.1
 -0.8
 -0.1
 -1.8



13 porb P450 (cytochrome) oxidoreductase b 327556 3.7 2.0
-1.5
-1.7
 0.6
 1.0
 0.7
 0.1
 1.8
 0.2
 -0.8
 1.7
 0.1
 1.7
 1.5
 0.8
 -0.3
 1.1
14 snx9a sorting nexin 9a 368424 3.7 2.0
0.3
-0.3
 -0.4
 0.8
 -0.1
 0.5
 -0.7
 0.6
 0.6
 1.0
 -0.2
 1.1



15 oscp1b organic solute carrier partner 1b 100334608 3.7 1.9
0.6
 -0.6
 -0.4
 -0.7
 -1.5
 -0.2
 -0.6
 -1.2
 -0.4
 -0.2
 0.0
 0.8
-0.8
 -0.1
16 aldh1l1 aldehyde dehydrogenase 1 family, member L1 100526683 3.6 1.9
-0.4
-1.2
 0.6
-0.4
 0.4
-0.1
 0.4
-0.8
 -0.2
-0.9
 -2.4
 -1.1
 -0.8
 0.5
-0.7
 0.4
0.4
 2.4
0.8
 -0.0
 1.0
 -0.1
 -0.3
17 cyp8b2 cytochrome P450, family 8, subfamily B, polypeptide 2 100004274 3.6 1.9
-0.9
-1.3
 3.0
 0.2
 1.3
 1.7


1.2
 1.3
 0.7



18 cyp1a cytochrome P450, family 1, subfamily A 140634 3.6 1.5
 1.9
 -0.3
 1.8
1.0
 0.7
-0.5
 0.2
-1.2
 1.3
-0.1
 0.7
-0.1
 2.1
1.6
 3.5
2.4
 -0.3
 1.2
 0.4



19 gnmt glycine N-methyltransferase 403338 3.6 1.6
 1.8
 -1.4

-1.6
 -0.8
 2.3
 0.7
 1.3
 2.1
 1.2
 1.9
 1.1


20 dhrs9 dehydrogenase/reductase (SDR family) member 9 322529 3.5 1.6
 1.7
 -0.2
-1.1
 1.6
1.4
 2.5
0.5
 1.3
0.5
 2.8
1.0
 1.7
0.2
 0.6
-0.5
 0.5
0.2
 2.2
0.8
 2.1
0.0
 2.3
1.7
 -0.0
 3.0
1.3
 0.4
-0.8
 -0.0
-0.4
21 plpp1a phospholipid phosphatase 1a 569053 3.5 1.0
 2.3
 0.9
0.3
 -0.7
-1.1
 1.4
0.3
 0.7
0.4
 0.9
-0.3
 1.3
-0.2
 0.4
-0.8
 0.5
-0.8
 1.5
1.4
 -0.0
-1.8
 1.9
-0.2
 3.4
2.7
 1.3
-0.1

22 atp11c ATPase phospholipid transporting 11C 368385 3.4 1.8
0.0
 -0.9
 0.5
 -1.0
 -0.5
 2.4
 0.4
 -0.4
 -1.3
 0.4
 -0.7



23 aldh8a1 aldehyde dehydrogenase 8 family, member A1 447801 3.4 1.5
 1.7
 -0.6
 1.5
 1.3
 -1.2
 -0.6
 -0.1
 0.8
 5.2
 0.8
 1.0
 0.3
1.4

24 hsd11b1lb hydroxysteroid (11-beta) dehydrogenase 1-like b 100333777 3.4 1.8
0.6
-0.5
 1.6
-0.9
 2.0
0.8
 1.2
-0.8
 0.3
-0.2
 2.1
-0.2
 -0.5
-0.6
 3.2
-0.0
 1.9
-0.8
 0.5
0.2
 0.7
0.0



25 slc51a solute carrier family 51 subunit alpha 447807 3.4 1.8
-1.2
 1.6
 2.0
 -0.2
 1.5
 -0.2
-0.3
 1.4
0.6
 2.5
0.6
 1.5





26 myo1ca myosin Ic, paralog a 567536 3.4 1.8
0.6
-1.0
 1.2
0.0
 3.5
0.1
 -0.1
-0.5
 0.8
-0.1
 1.3
0.5
 2.3
1.6
 0.7
-0.3
 3.5
1.6
 1.1
0.2
 3.4
0.1
 -0.5
-0.5
 -1.1
27 entpd8 ectonucleoside triphosphate diphosphohydrolase 8 436652 3.3 1.8
-1.8
 0.7
 1.4
 -0.4
 1.1
 1.5
1.0
 1.0
-0.1
 1.1
1.0
 0.1





28 pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 406598 3.3 1.5
 1.6
 -0.9
 -0.9
 -1.1
 0.0
 0.2
 0.0
 -0.4
 -1.1
 0.1
 -0.6
 1.0



29 ephx1 epoxide hydrolase 1, microsomal (xenobiotic) 394043 3.3 1.5
 1.6
 0.6
-0.8
 -0.6
 1.5
 -0.7
 -0.1
 0.4
0.4
 1.4
-0.9
 1.5
0.7
 1.0
 -0.2
 0.5
 2.7
2.4
 1.6
1.3

30 sod1 superoxide dismutase 1, soluble 30553 3.3 1.7
 1.4
 -1.8
 -0.4
 -0.9
 -0.0
 0.6
 0.5
 0.8
 0.8
 1.1
 1.1
 0.6
 1.8
 0.6
0.1

31 slc27a4 solute carrier family 27 member 4 550432 3.3 1.7
0.3
0.3
 1.2
0.5
 1.5
1.2
 1.3
0.4
 1.3
0.3
 0.8
-0.9
 0.4
0.3
 3.8
0.3
 1.0
0.9
 -0.3
-0.3
 0.5
0.4
 3.5
0.6
 1.6
1.5
 -0.3
 -0.4
32 st6galnac5b ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5b 407716 3.3 1.7
0.1
0.1
 -1.1
 -0.5
 -0.7
 -0.5
 -1.1
 -1.1
 -0.1
 -0.6





33 zgc:64106 zgc:64106 393348 3.3 1.2
 1.9
 1.7
1.2
 0.4
0.3
 1.5
0.3
 0.1
-0.3
 -0.4
-0.7
 3.2
0.6
 0.4
0.4
 0.9
0.3
 0.2
0.0
 1.7
1.2
 2.0
1.4
 3.3
3.1
 1.2
-0.7

34 pam peptidylglycine alpha-amidating monooxygenase 570822 3.3 1.7
-0.4
 -1.0
 0.9
 -0.1
 -0.2
 0.1
 1.3
 -0.1
 -0.6
 -0.4
 1.0
 -0.2
-0.2
 2.1
-0.3
 -1.0
 -1.3
35 nt5e 5'-nucleotidase, ecto (CD73) 393906 3.2 1.1
 2.0
 -0.9
 -0.3
 0.7
 0.3
 0.1
 -0.4
 -1.9
 -1.5
 0.9
 0.5
 1.3
 1.8
-0.0
0.3
 -0.1
36 crata carnitine O-acetyltransferase a 449545 3.2 2.0
 1.0
 0.6
-0.2
 0.7
 3.2
 1.3
0.2
 0.5
0.4
 0.9
 0.7
 0.4
 1.2
 0.6
 1.5
 1.6
0.0
 0.7
-0.2

37 akr1b1.2 aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2 553452 3.2 1.8
 1.2
 0.6
-0.4
 2.8
0.8
 1.9
1.7
 2.9
2.7
 4.5
2.3
 2.6
1.2
 0.4
0.2
 1.0
1.0
 1.5
1.0
 0.7
0.2
 1.9
0.9
 1.9
1.1
 1.2
0.4

38 rgs4 regulator of G protein signaling 4 569876 3.2 1.6
 1.4
 1.0
0.9
 -0.5
 -1.4
 0.9
 0.7
 0.2
 0.2
 -0.3
 -1.3
 0.6
 0.3
0.8
-0.1

39 prkcda protein kinase C, delta a 334571 3.2 1.6
 1.4
 1.0
0.7
 0.0
-0.1
 0.8
0.5
 1.4
-0.0
 0.6
0.4
 0.4
0.0
 0.7
-0.0
 0.7
0.1
 -0.4
-0.4
 0.3
0.0
 1.6
-0.1
 1.4
0.2
 0.8
0.5
 -0.2
 0.7
40 sphk2 sphingosine kinase 2 100150090 3.2 1.7
0.0
 0.4
-0.7
 2.1
0.9
 1.6
-0.2
 1.8
0.5
 1.0
 -1.1
 -0.5
 -0.5
-0.6
 0.6
-0.0
 0.5
-0.0
 0.8
-0.3
 0.2
 0.4
 1.0
41 hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 768185 3.1 1.7
-0.9
 0.6
 0.5
 -0.2
 0.3
 0.6
 1.5
 -0.2
 1.7
 -0.1
 1.6



42 ccdc18 coiled-coil domain containing 18 564276 3.1 1.7
0.2
-0.8
 0.1
 0.2
 0.5
 0.0
 -0.6
 0.6
 -2.0
 -1.5
 -1.3
 -0.4



43 aktip akt interacting protein 378716 3.1 1.5
 1.4
 0.0
 0.1
 0.2
 -0.7
 -0.5
 -0.9
 -0.2
 -0.8
 1.9
 0.3
 1.0
 -0.0
-1.0
 0.8

44 gse1a Gse1 coiled-coil protein a 100538211 3.1 1.7
0.9
-0.5

-0.9
 -0.5
 0.4
 -0.4
 0.2
 -0.4
 -1.0
 -1.1
 0.3


45 thrab thyroid hormone receptor alpha b 558427 3.1 1.7
-0.1
-0.3
 0.4
-1.3
 0.8
0.6
 -0.6
-1.1
 -0.1
-0.8
 0.6
-0.0
 0.4
-0.4
 0.6
0.1
 -0.5
-1.6
 0.8
-1.0
 0.9
-0.8

0.2
 0.3
46 tmem185 transmembrane protein 185 393409 3.1 1.7
-0.1
 -0.8
 0.8
 0.3
-0.3
 0.3
-0.0
 -1.0
 0.6
 0.1
 0.1
-0.9
 0.3
-1.0
 1.6
-0.1
 -0.5
 -0.3

47 rnf128a ring finger protein 128a 322325 3.1 0.9
 2.0
 -1.7
 1.8
 1.3
 -1.0
 -1.4
 -0.1
 0.2
 -0.3
 1.0
 1.2
 1.1



48 pon3.2 paraoxonase 3, tandem duplicate 2 568655 3.1 0.4
 2.5
 0.4
-0.8
 1.4
1.3
 1.2
0.9
 -0.5
-1.1
 -0.3
-0.4
 -0.6
 0.7
 0.6
 1.0
0.6
 2.4
0.3
 0.3
-0.2
-0.2
-0.2
 0.3
0.0
 1.7
0.2
49 fdx1 ferredoxin 1 100126232 3.1 1.1
 1.8
 -0.2
 1.8
 -0.6
 2.5
 1.8
 1.8
0.8
 2.4
0.9
 1.6
1.0
 0.1
 0.7
 -1.4
 0.2
1.1
0.1
 0.3
-0.3
50 hivep1 HIVEP zinc finger 1 100000517 3.1 1.6
0.4
-0.4
 -0.1
-0.5
 0.2
-0.0
 0.1
-0.1
 0.3
-0.3
 1.0
0.8
 0.4
-0.2
 -0.8
-0.9
 -0.1
-0.2
 0.2
-1.2
 0.9
0.2
 -1.3
 -1.2

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