Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3  pfkfb1  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 dre-r.3  pfkfb1  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 dre-m.5  pfkfb1  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 dre-u.3  pfkfb2b  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b 
 dre-u.3  pfkfb4a  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a 
 hsa-u.4  PFKFB2  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 hsa-u.4  PFKFB3  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 
 mmu-u.4  Pfkfb2  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 mmu-u.4  Pfkfb1  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 mmu-u.4  Pfkfb4  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 
 rno-u.3  Pfkfb3  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 
 rno-u.3  Pfkfb2  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 gga-u.3  PFKFB4  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 
 gga-u.3  PFKFB1  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 gga-u.3  PFKFB2  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 mcc-u.3  PFKFB4  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 
 mcc-u.3  PFKFB2  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 mcc-u.3  PFKFB3  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 
 cfa-u.3  PFKFB4  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 
 cfa-u.3  PFKFB2  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 cfa-u.3  PFKFB3  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 
 dme-u.3  Pfrx  6-phosphofructo-2-kinase 
 cel-u.3  pfkb-1.1  6-phosphofructo-2-kinase 
 cel-u.3  pfkb-1.2  Fructose-2,6-bisphosphatase 
 sce-u.3  YLR345W  bifunctional fructose-2,6-bisphosphate 2-phosphatase/6-phosphofructo-2-kinase 
 sce-u.3  FBP26  fructose-2,6-bisphosphatase 

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Top 50 coexpressed genes to pfkfb1 (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre3008   Ribosome biogenesis in eukaryotes  4 75 4.46
 dre830   Retinol metabolism  2 93 -
 dre564   Glycerophospholipid metabolism  2 112 -
 dre1240   Biosynthesis of cofactors  2 202 -
 dre4020   Calcium signaling pathway  2 377 -

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dre:pfkfb1 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1) External Links;


Show/Hide Columns:        
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID
Other ID LINK Target Reference

dre-u.3
for
pfkfb1


dre-r.3
for
pfkfb1


dre-m.5
for
pfkfb1


dre-u.3
for
pfkfb2b


dre-u.3
for
pfkfb4a


hsa-u.4
for
PFKFB2


hsa-u.4
for
PFKFB3


mmu-u.4
for
Pfkfb2


mmu-u.4
for
Pfkfb1


mmu-u.4
for
Pfkfb4


rno-u.3
for
Pfkfb3


rno-u.3
for
Pfkfb2


gga-u.3
for
PFKFB4


gga-u.3
for
PFKFB1


gga-u.3
for
PFKFB2


mcc-u.3
for
PFKFB4


mcc-u.3
for
PFKFB2


mcc-u.3
for
PFKFB3


cfa-u.3
for
PFKFB4


cfa-u.3
for
PFKFB2


cfa-u.3
for
PFKFB3


dme-u.3
for
Pfrx


cel-u.3
for
pfkb-1.1


cel-u.3
for
pfkb-1.2


sce-u.3
for
YLR345W


sce-u.3
for
FBP26

1 itih6 inter-alpha-trypsin inhibitor heavy chain family member 6 565328 4.6 2.4

0.8
-0.0
-1.0
-0.5





0.4
0.0
1.7











2 rrp12 ribosomal RNA processing 12 homolog 563195 4.2 2.2

0.0
-0.3
1.5
2.5
0.8
-0.6
1.9
0.5
-0.3
-0.5
-0.0
-0.8
2.3
2.4
1.4
1.6
1.3
2.3
1.6
-2.4
-0.7
-1.0
-1.1
3 sdad1 SDA1 domain containing 1 286746 4.1 2.2
1.6
-0.8
0.3
-0.5
-2.3
-0.3
-0.6
0.2
0.5
-0.7
-1.2
-1.5
-0.6
-1.4
-0.3
-0.9



0.5
-1.3
-1.0
0.1
0.6
4 utp4 UTP4 small subunit processome component 406571 4.1 2.7
1.1
-0.2
0.7
-0.8
0.5
-0.6
-0.4
-0.6
0.6
-0.4
-1.0
-1.1
0.1
-1.5
-0.6
0.5
0.0
-0.1
-0.3
-0.1
0.8
0.8
0.8
-0.5
5 znhit6 zinc finger HIT-type containing 6 100332549 4.1 2.2

-0.3
1.4
1.0
-0.2
-1.8
-0.4
-1.7
-1.0
-0.8
1.0
-0.3
-1.4
-1.9
0.0
-0.6
-0.8
-0.6
-0.9
-0.2
-0.6
0.4
-0.2
-1.6
6 msrb1a methionine sulfoxide reductase B1a 352916 4.0 2.3
1.4
-0.1
-1.1
1.7
0.9
-0.7
0.6
-0.8
0.8
1.6
0.7
-1.0
-0.3
0.7
0.4
2.9
1.3
-0.2
0.8
1.7
-1.1





7 stim2a tromal interaction molecule 2a 100334881 3.8 2.0

1.1
0.4
0.4
0.4
1.7
-0.6
0.5
-0.2
-0.1
-1.2
0.2
-1.1
1.2
-0.3
0.1
-0.2
-0.2
-0.4
-1.1
-2.5
0.2
-0.3
0.9
-0.5
0.7
-0.2
-1.1
-2.0
1.6
-0.4
2.7
-0.5
0.4
-1.4
1.7
1.5
-0.3
1.8
2.1


8 dph2 diphthamide biosynthesis 2 562538 3.8 2.0

0.4
0.3
1.0
-0.6
-0.3
-0.9
1.5
0.6
1.1
-1.3
0.2
-0.4
-0.7
-0.9
-0.4
0.4
0.4
-0.4
1.1
-0.8
1.3
-1.3
-1.2
9 ngrn neugrin, neurite outgrowth associated 569275 3.8 2.0

-0.8
1.7
-0.1
-0.3
0.1
-0.2
-0.2
-0.3
2.2



-0.2
0.8
0.9
-0.7
0.2
0.3
-0.2




10 b4galnt3b beta-1,4-N-acetyl-galactosaminyl transferase 3b 553524 3.7 2.0

1.2
2.1
0.7
0.4
0.4
0.2
0.8


-0.3
-0.4
-0.5
-1.4
0.3
-0.7
0.1
-0.1
0.9





11 tpcn2 two pore segment channel 2 777614 3.7 1.9

-0.5
1.5
1.9
1.2





0.0
0.2
-0.5
2.7
-1.6
-1.6
2.8
1.6
-0.7





12 coq8aa coenzyme Q8A, genome duplicate a 437001 3.6 2.3
1.1
1.3
0.7
2.6
1.3
1.0
0.7
0.8
0.7
1.4
-0.7
1.0
0.4
1.8
-0.9
0.3
-0.4
1.0
-0.8
0.2
0.9
-0.5
1.3
-1.2
1.3
-1.2
-0.8
-0.9
0.9
0.6
1.1
-0.5
0.7
0.7
0.8
0.8
3.1
-1.4
-1.0
13 mical2b microtubule associated monooxygenase, calponin and LIM domain containing 2b 569564 3.6 1.9

1.9
0.7
2.5
-1.0
0.8
-0.3
1.1
-0.1
0.8
2.2
0.4
2.3
-0.1
-0.9
-0.1
-0.0
-1.6
-0.3
-0.9
0.8
-0.2




14 fhip2b FHF complex subunit HOOK interacting protein 2B 777718 3.5 1.9
























15 asap3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 664764 3.5 1.9

0.7
0.8
1.2
-0.9
1.0
-0.1
0.4
-0.6
0.5
0.5
-0.3
0.9
0.1
2.1
-1.1
1.4
0.3
-1.4





16 ognb osteoglycin, paralog b 100170815 3.5 1.9

1.5
0.4
-0.7
-1.7
0.1
-0.6
-0.5
-0.6
-0.2
0.4
-0.4
-0.3
-0.3
-0.6
2.0
-0.4
-0.2
-1.5





17 klhl38b kelch-like family member 38b 563341 3.5 1.9

1.0
1.1
0.7
-0.5
0.8
0.8
0.1
-0.2
-0.4
0.4
-0.1
-0.8



1.2
-0.0
-1.0





18 crls1 cardiolipin synthase 1 405867 3.5 2.4
0.9
0.3
1.0
0.4
0.0
-0.6
1.0
-1.9
0.3
-1.2
-2.0
-0.7
0.4
-1.1
-0.7
-0.2
-0.5
-1.2
-1.3
0.5
2.0
2.2
-0.3
1.4
19 mtrf1 mitochondrial translational release factor 1 503530 3.5 1.8

0.2
-1.5
-0.2
-1.0
0.0
4.2
-0.7
0.5
0.3
-1.6
1.3
-0.9
0.2
-0.9
-0.4
-0.4
0.8
-1.5





20 zgc:161973 zgc:161973 556635 3.4 1.2
2.0
2.8
1.1
0.3
-0.1


0.2
0.5
-0.5
0.1
0.5
-0.0
-0.8
0.0
-0.2
0.5
-0.1








21 cep63 centrosomal protein 63 393574 3.4 1.8

-0.5
1.6
0.5
-0.4
0.6
0.3
0.1
-0.9
0.2
-0.4
-0.7
0.7
-0.8
1.3
0.1
-1.5
-0.9
0.3





22 metap1d methionyl aminopeptidase type 1D (mitochondrial) 554090 3.4 1.8

-0.8
1.1
-0.2
-1.2
3.0
2.5
-0.4
-0.0
-1.2
-0.6
0.1
2.0
-0.4
-0.7
0.9
-0.2
-0.6
0.3
-1.4




23 si:dkey-238d18.4 si:dkey-238d18.4 796120 3.4 1.8
























24 rdh14a retinol dehydrogenase 14a 450010 3.4 1.8

1.5
0.5
3.5
1.4
2.0
1.2
2.1
0.7
2.3
0.4
1.0
0.6
2.4
1.6
-0.4
-0.7
0.5
0.0
0.6
0.3
2.5
0.1
1.0
0.4
-0.0
-0.1
0.5
0.5
1.3
1.0
1.5
1.1
2.6
1.5
1.3
0.8
1.0
0.5
4.0
2.1
3.2
2.8
-0.7
-0.6
25 lsg1 large 60S subunit nuclear export GTPase 1 323464 3.3 1.6
1.5
0.3
-0.0
0.4
-0.3
-0.7
-0.6
-0.4
-0.8
1.2
0.3
-0.5
0.2



-0.7
-0.4
0.1
2.6
1.7
-0.2
1.0
-0.7
26 c19h1orf109 c19h1orf109 homolog (H. sapiens) 286778 3.3 1.5
1.6
-0.9
-1.5
1.2
-0.5
0.9
-0.8
1.2
1.2
1.6
-1.1
1.3
-0.5
1.7
-0.3
-0.1
-0.4
1.0
-0.4





27 sec16b SEC16 homolog B, endoplasmic reticulum export factor 553356 3.3 1.8

0.1
-0.8
0.5
-0.0
1.4
1.2
1.5
1.4
1.9
-0.6
0.4
0.2
-0.8
-1.6
1.6
-0.3
-0.6
-1.4
0.4
-0.6
0.3
0.3
-0.9
-1.1
-0.3
-0.8
-0.7
-1.0
1.6
-1.0
1.5
-0.3
1.9
-0.5
-0.9
0.2
0.2
-0.4
-2.6
-1.5
-0.6
28 lmbr1l limb development membrane protein 1-like 321314 3.3 1.5
1.6
-0.1
-0.9
1.2
0.3
0.9
-1.1
1.5
0.7
3.0
-0.7
1.1
0.1
1.8
0.9
1.6
-0.4
2.6
1.5
2.2
0.3
0.2
-0.5
1.1
1.0
1.5
-0.6
0.9
-0.8
0.0
-0.5
0.5
-0.1
1.1
1.0
0.3
-1.2
-1.3
1.4
4.2


29 cyp2p7 cytochrome P450, family 2, subfamily P, polypeptide 7 100034406 3.3 1.8

1.9
1.8
0.8
0.1
-0.1
-1.1
0.8
-0.9
0.5
0.2
-0.7
-0.9
0.4
0.4
0.4
-1.0
0.5
-0.2
2.6
2.4
1.6
0.5
-1.2
1.3
0.1
-0.5
0.1
-0.7
0.3
0.3
1.0
0.7
1.1
0.5


30 erich1 glutamate rich 1 100002532 3.3 1.8

-0.0
1.0


-0.5
-0.4
-0.4
0.9
0.5
-1.0
-1.7
-0.6
1.0
0.3
1.2
-0.8
-0.4
1.5





31 rpp30 ribonuclease P/MRP 30 subunit 541352 3.3 1.7

1.1
-0.8
-1.5
-0.9
-1.8
0.9
-0.1
0.3
-0.8
0.6
-0.6
-1.0
0.4
-2.0
-1.8
-0.5
-0.3
-0.9
-0.9
-0.6
1.0
-1.4
-1.6
32 LOC566640 solute carrier family 22 member 6-like 566640 3.2 1.7

1.6
1.1
1.1
1.0
3.5
2.0
0.8
0.6
2.4
0.7
2.7
1.0
1.5
1.5
1.0
0.9
1.1
1.1
2.6
1.3
1.0
0.9
1.3
1.1
3.2
1.1
0.5
0.3
1.6
0.9
1.0
1.0
1.8
1.5
1.8
0.6
1.7
1.6
2.3
1.9
2.3
1.4


33 acy3.1 aspartoacylase (aminocyclase) 3, tandem duplicate 1 791456 3.2 1.7
























34 selenop2 selenoprotein P2 791479 3.2 1.6
1.4
-1.4
-1.4
0.3
-0.5
0.2
-0.6
-0.3
-0.5
-0.5
-1.3
-0.6
2.7
1.2
1.4
-0.7
0.9
0.5
0.2
-0.8
1.1
-1.2
0.2
-1.3





35 ddx31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 325248 3.2 1.5
1.5
0.1
0.2
0.8
0.9
1.1
0.9
1.0
-0.5
-0.3
1.9
-0.8
-0.6
-0.9
0.9
-0.8
-0.4
0.6
-0.5
0.6


-0.9
-1.3
36 ivd isovaleryl-CoA dehydrogenase 368775 3.2 1.9
1.1
2.3
0.9
1.0
-0.7
1.0
1.7
-0.3
-0.8
0.3
0.3
-0.4
0.1
1.7
0.7
3.0
2.8
2.0
0.3
0.5
0.3
0.1


37 si:dkey-239h2.3 si:dkey-239h2.3 100537903 3.2 1.7
























38 etnppl ethanolamine-phosphate phospho-lyase 393421 3.2 1.3
1.7
0.6
0.3
-0.5
-1.2
0.7
-0.9
-0.6
-0.7
0.2
0.2
2.2
1.0
-0.8
-0.9
-0.1
-0.3
0.8
-0.6
-0.4
-0.6
0.7
0.3
0.1
-0.2
-0.2
-0.5
1.6
0.2
1.7
0.6
0.7
-0.1
0.9
0.9
0.6
0.3
3.6
1.4
-0.8
-1.0
1.0
-0.2


39 metap1 methionyl aminopeptidase 1 503783 3.1 2.4
0.6
0.3
0.1
-1.3
-0.7
0.9
1.7
0.3
0.6
0.4
0.0
-0.7
-1.1
0.0
-2.0
-1.5
0.2
1.2
-0.8
-0.2


0.1
-0.1
40 arhgap36 Rho GTPase activating protein 36 559813 3.1 1.7

0.2
-0.0
3.2
1.2
-0.3
0.3
-0.8
-0.9
-0.5
-0.5
-1.1
1.1
-0.5
-0.6
-0.7
-0.2
-1.4
1.4
-1.3
0.5
0.0
-0.7
-0.0
0.8
-1.4
-0.1


41 whamm WAS protein homolog associated with actin, golgi membranes and microtubules 110438074 3.1 1.7

-0.4
-0.1
0.5
1.1
0.8
0.8
-0.6
1.9
0.7
-0.1
0.6
-0.3
-0.1
0.3
0.1
-0.3
1.0
-1.2





42 tmem106a transmembrane protein 106A 407612 3.1 1.6
1.3























43 tsen54 TSEN54 tRNA splicing endonuclease subunit 553550 3.1 1.6

0.2
0.5
-0.0
-0.7
-0.5
-1.5
0.3
-1.5
-0.0
1.7
0.6
2.0
1.6
-1.5
-1.0
-0.7
-0.1
0.1
-1.6
-0.1
-0.8
0.9
-0.6
44 ugt5g1 UDP glucuronosyltransferase 5 family, polypeptide G1 570913 3.1 1.6

1.5
1.3
2.1
1.0
0.2
-0.1
-0.3
-0.4
1.1
0.7
2.2
1.6
1.5
0.1
0.6
0.2
1.1
0.5
0.3
-0.1
0.7
-0.4
1.7
0.2
-0.7
-0.8
0.3
-0.1
0.5
0.4
-0.1
-0.6
0.7
-0.3
0.5
-0.9
2.7
1.0
1.2
1.0
2.0
1.8
1.4
0.3
45 dusp22a dual specificity phosphatase 22a 436787 3.1 1.3
1.5
0.7
-0.3
1.8
1.0


-0.8
1.8
0.8
0.5
-1.3
-0.3
-0.9
1.8
-0.1
0.4
-0.6
1.0
-0.2
-0.9
2.3
-0.4
1.1
0.6
1.2
0.6
-0.3
2.1


46 acsl5 acyl-CoA synthetase long chain family member 5 447860 3.1 1.6

1.4
-0.2
1.8
1.6
1.8
0.3
3.6
-0.8
0.4
0.3
3.8
0.9
1.0
-0.7
0.8
-0.4
1.5
-0.5
1.3
0.1
2.7
1.4
0.2
-0.1
2.4
0.2
1.4
0.4
2.8
0.3
2.0
0.9
1.2
1.1
1.7
0.1
1.0
1.0
0.6
0.9
0.5
0.7
-0.5
47 cbsa cystathionine beta-synthase a 550524 3.1 1.6

0.6
0.1
1.5
0.5


0.2
-0.8
-1.4
-1.4
-1.3
1.3
-0.6
1.4
1.3
0.7
-0.3
-0.4
0.5
-0.5
-0.3
1.4
0.1
0.8
0.7
0.5
1.5
-0.4
0.6
-0.2
48 ganc glucosidase, alpha; neutral C 100536353 3.1 1.6

1.2
-0.1
1.4
0.4
1.7
-0.8
0.5
-0.6
1.6
0.8
1.7
-0.4
0.8
-0.8
1.2
-1.5
2.1
-0.8
0.5
2.9
-1.1
0.6
0.6
3.3
-1.0
1.7
-0.4
2.4
1.4
1.3
-0.3
1.0
0.8
0.3
1.4
-0.5
0.7
0.2
-0.0
-1.8
49 rcl1 RNA terminal phosphate cyclase-like 1 445388 3.1 1.7
1.1
-1.8
-0.1
-0.3
1.5
-1.9
0.9
-1.3
-0.3
-1.6
0.7
-0.2
0.6
-1.3
0.0
0.8
1.0
0.5
0.2
-0.6
-0.4
1.4
-0.1
-0.6
50 bco1 beta-carotene oxygenase 1 84039 3.0 1.4
1.5
1.4
-1.4
1.8
1.8


2.2
1.0
-0.2


0.2
0.7
-1.0
-0.2
-0.0
0.6




0.1
-0.2


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