Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3   syde2   synapse defective 1, Rho GTPase, homolog 2 (C. elegans) 
 dre-r.3   syde2   synapse defective 1, Rho GTPase, homolog 2 (C. elegans) 
 dre-u.3   syde1   synapse defective Rho GTPase homolog 1 
 hsa-u.4   SYDE2   synapse defective Rho GTPase homolog 2 
 hsa-u.4   SYDE1   synapse defective Rho GTPase homolog 1 
 mmu-u.4   Syde2   synapse defective 1, Rho GTPase, homolog 2 (C. elegans) 
 mmu-u.4   Syde1   synapse defective 1, Rho GTPase, homolog 1 (C. elegans) 
 rno-u.3   Syde2   synapse defective Rho GTPase homolog 2 
 rno-u.3   Syde1   synapse defective Rho GTPase homolog 1 
 gga-u.3   SYDE1   synapse defective Rho GTPase homolog 1 
 gga-u.3   SYDE2   synapse defective Rho GTPase homolog 2 
 mcc-u.3   SYDE2   synapse defective Rho GTPase homolog 2 
 mcc-u.3   SYDE1   synapse defective Rho GTPase homolog 1 
 cfa-u.3   SYDE1   synapse defective Rho GTPase homolog 1 
 cfa-u.3   SYDE2   synapse defective Rho GTPase homolog 2 
 dme-u.3   RhoGAP100F   Rho GTPase activating protein at 100F 
 cel-u.3   syd-1   Rho GTPase-activating protein syd-1 

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Top 50 coexpressed genes to syde2 (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre4910   Insulin signaling pathway  4 172 3.08
 dre4530   Tight junction  4 230 2.61
 dre4270   Vascular smooth muscle contraction  3 153 2.20
 dre4068   FoxO signaling pathway  3 173 2.05
 dre4010   MAPK signaling pathway  4 409 -

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dre:syde2 (synapse defective 1, Rho GTPase, homolog 2 (C. elegans)) External Links;


Show/Hide Columns:        
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dre-u.3
for
syde2
dre-r.3
for
syde2
dre-u.3
for
syde1
hsa-u.4
for
SYDE2
hsa-u.4
for
SYDE1
mmu-u.4
for
Syde2
mmu-u.4
for
Syde1
rno-u.3
for
Syde2
rno-u.3
for
Syde1
gga-u.3
for
SYDE1
gga-u.3
for
SYDE2
mcc-u.3
for
SYDE2
mcc-u.3
for
SYDE1
cfa-u.3
for
SYDE1
cfa-u.3
for
SYDE2
dme-u.3
for
RhoGAP100F
cel-u.3
for
syd-1
1 LOC101884560 uncharacterized LOC101884560 101884560 19.6 10.1














2 lats2 large tumor suppressor kinase 2 567674 5.8 3.0
 2.8
2.2
 3.5
1.5
 5.0
0.7
 0.7
0.3
 4.4
-0.4
 2.0
1.5
 4.6
0.2
 2.0
0.1
 4.3
0.6
 2.8
0.4
 1.0
0.6
 2.2
0.9
 2.6
1.1
 0.1
3 mbd6 methyl-CpG binding domain protein 6 561863 5.0 2.6
 2.0
 -0.4
 1.0
 -0.6
 1.2
 -0.4
 0.9

-0.8
 -0.5
 0.8
 -0.2

4 si:ch211-126j24.1 si:ch211-126j24.1 571137 5.0 2.6
 2.4
2.2
 0.7
0.1
 1.0
-0.5
 -0.9
-1.5
 1.9
-0.9
 1.3
-1.0
 0.3
-0.0
 1.7
-0.0
 1.0
-0.0
 -0.1
-1.6
 1.0
-0.2
 0.8
0.7
 0.2
-0.8
 0.5
 2.2
5 smg7 SMG7 nonsense mediated mRNA decay factor 565575 4.9 2.6
 1.1
 -0.3
 -0.2
 -0.5
 0.9
 -1.1
 -0.6
 1.1
 0.3
 -0.8
 -1.7
 -1.2
 -2.2
0.4
6 tulp4a TUB like protein 4a 557730 4.8 2.5
 1.0
-1.0
 0.8
 -1.5
 -0.2
 -1.5
 0.9
 -0.2
 1.3
 -0.2
 0.5
 -0.8
 -1.1
 0.5
 2.5
 0.2
7 si:dkey-46g23.1 si:dkey-46g23.1 793145 4.8 2.5
 2.8
2.1
 -0.4
 -1.3
 -0.5
 -0.7
 1.0
 -1.3
 -0.4
 -0.8
 0.3
 0.3
 -0.4
 -0.9

8 usp6nl USP6 N-terminal like 561983 4.7 2.5
 1.1
0.4

0.4
 1.0
 1.1
 -0.3
 1.9
0.6
 0.3
-0.5
 -0.3
 -0.3
 -0.4
 1.6
 0.2
9 jarid2a jumonji, AT rich interactive domain 2a 100007426 4.6 2.4
 1.6
1.2
 -1.2
 -1.8
 0.6
 -2.4
 0.2
 -1.5
 -0.4
 -1.0
 -1.0
 -1.4
 -1.6
 -1.7
 -0.0
10 fez2b fasciculation and elongation protein zeta 2b 565010 4.5 2.4
 2.7
2.3
 -0.6
-0.9
 0.7
0.5
 0.3
-0.6
 3.4
1.3
 1.1
-0.3
 0.6
-0.3
 0.7
-0.2
 -0.1
-0.3
 0.3
-1.1
 1.6
0.3
 0.5
-0.3
 0.7
-1.2
 -0.3
 2.8
11 arhgap21b Rho GTPase activating protein 21b 326745 4.4 2.3
 1.1
 -1.2
 0.1
 2.7
 0.5
 2.2
 0.6
 -0.6
 1.3
 -1.0
 -1.4
 0.6
 0.0

12 phlpp1 PH domain and leucine rich repeat protein phosphatase 1 100331906 4.3 2.3
 0.7
 2.1
0.2
 0.5
0.1
 1.6
0.5
 0.7
0.2
 2.5
1.2
 0.3
0.1
 0.3
0.0
 1.8
-0.5
 0.3
0.0
 -0.3
-0.3
 1.2
-0.5
 0.3
-0.4
2.1
13 arid3a AT rich interactive domain 3A (BRIGHT-like) 562799 4.3 2.3
 2.7
2.7
 0.7
0.1
 1.0
-0.5
 -0.6
-1.0
 -0.1
-1.3
 0.7
0.2
 1.2
0.3
 1.6
0.9
 0.1
-0.2
 0.2
-1.3
 0.4
0.4
 1.2
0.0
 -0.6
-1.4
 -1.0
 3.5
14 gramd1a GRAM domain containing 1A 555994 4.3 2.3
 2.8
0.8
 0.5
-1.0
 1.4
-0.2
 0.1
-1.5
 -0.4
-0.7
 0.4
-1.1
 0.1
-0.3
 0.6
-0.4
 0.4
0.1
 2.7
-0.7
 0.8
-0.7
 1.0
-0.7
 1.1
-1.3
 -0.5
-0.8
 0.5
15 kmt2a lysine (K)-specific methyltransferase 2A 557048 4.3 2.3
 1.6
 1.0
 0.2
 -0.7
 1.5
 0.1
 0.4
 0.6
 0.1
 0.8
 -0.9
 -0.4
 0.1

16 pias1a protein inhibitor of activated STAT, 1a 564496 4.3 2.3
 1.7
1.4
 0.8
0.3
 1.3
1.0
 1.7
-0.4
 1.4
0.6
 0.8
-0.2
 2.1
0.8
 4.3
1.1
 1.8
0.1
 0.7
-0.1
 0.4
0.4
 1.0
0.6
 0.3
-0.5
 0.6
 0.7
17 epc1a enhancer of polycomb homolog 1 (Drosophila) a 566686 4.3 2.3
 0.6
0.6
 0.7
 0.7
 0.5
 0.3
 0.8
-1.1
 0.3
-1.0
 -0.4
-1.0
 -0.4
-0.7
 0.6
-0.7
 0.1
-1.0
 -0.0
-0.6
 1.4
-0.1
 2.0
 0.8
18 leng8 leukocyte receptor cluster (LRC) member 8 100037367 4.2 2.2
 1.8
 -0.2
 0.5
 -1.1
 0.7
 -0.7
 1.4
 4.0
 0.4
 -0.5
 -0.7
 -1.0
 -1.1
 -0.3
 -0.0
19 dlg5b.1 discs, large homolog 5b (Drosophila), tandem duplicate 1 101883945 4.2 2.2
 4.6
2.2
 1.1
 1.2
 -0.2
 2.7
 2.9
 -0.6
 0.2
 -1.3
 -0.1
 1.1
 0.3
 1.2
 1.2
 1.2
20 LOC568955 zinc finger protein 513-like 568955 4.2 2.2
 3.3
-0.4
 -1.1
 -0.9
 -2.4
 0.9
 -1.2
 1.5
 0.9
 0.5
 -1.1
 -1.0
 -0.0
 -1.5

21 prkacaa protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a 564064 4.2 2.2
 2.2
2.1
 0.9
0.4
 0.8
-0.0
 1.3
-0.2
 0.8
-0.0
 -0.6
-0.6
 1.0
0.0
 -0.3
-1.5
 0.6
-0.4
 0.6
0.3
 -0.5
-0.6
 0.8
0.4
 0.5
0.3
 0.9
0.6
 2.0
1.8
22 brpf3b bromodomain and PHD finger containing, 3b 100003354 4.2 2.2
 2.4
1.9
 1.7
0.3
 1.0
0.3
 2.0
1.4
 1.4
-0.1
 1.2
1.1
 1.0
0.9
 2.0
0.7
 0.9
0.7
 0.5
-0.1
 0.9
0.1
 0.8
0.2
 -0.0
-0.5
 -0.6
 1.7
23 map3k21 mitogen-activated protein kinase kinase kinase 21 561518 4.1 2.2
 2.0
1.7
 2.6
1.0
 1.5
0.8
 2.4
0.0
 1.9
1.1
 1.9
0.3
 1.8
1.0
 -1.0
-1.0
 0.1
-0.4
 2.3
0.3
 0.2
-0.4
 1.3
0.8
 1.4
0.6
 1.2
 2.0
24 ttc14 tetratricopeptide repeat domain 14 541501 4.1 2.2
 1.9
 -0.5
 0.4
 -0.4
 -0.6
 1.6
 -0.6
 -1.1
 -0.1
 -0.8
 -1.7
 -1.0
 -0.4
 0.3
25 wwtr1 WW domain containing transcription regulator 1 568008 4.1 2.2
 4.5
0.9
 2.4
0.7
 4.0
3.0
 1.8
1.6
 2.8
2.3
 1.9
1.8
 3.6
2.9
 0.9
0.5
 1.8
1.1
 2.8
1.0
 2.3
1.9
 3.4
3.2
 2.3
1.6
 -1.0
 1.0
26 znf652 zinc finger protein 652 557571 4.1 2.2
 2.7
1.9
 -0.3
 3.2
 1.4
 2.5
 2.2
 1.4
 2.1
 0.4
 -0.0
 -0.2
 2.4
 0.7

27 hipk3a homeodomain interacting protein kinase 3a 564413 4.1 2.2
 2.3
2.2
 2.3
-1.0
 -0.2
-1.4
 0.3
0.1
 1.5
0.6
 1.5
1.3
 1.6
-0.4
 0.6
 1.3
0.3
 -0.0
-0.4
 -0.4
-0.4
 -0.0
-1.0
 0.8
-1.4
 2.6
 1.1
28 dlg1b discs large MAGUK scaffold protein 1b 497648 4.0 2.1
 2.4
2.4
 1.2
-0.0
 1.5
0.2
 3.0
0.6
 0.5
0.1
 2.7
0.4
 0.1
-0.1
 0.4
-0.5
 1.2
-1.2
 0.4
-0.3
 -0.9
-0.9
 0.0
-0.2
 2.4
0.9
0.6
29 insrb insulin receptor b 245700 4.0 2.1
 3.1
1.9
 2.5
0.4
 1.1
0.9
 2.3
2.0
 2.1
0.5
 2.8
1.0
 1.1
-0.0
 2.0
0.6
 1.1
0.6
 0.9
0.7
 0.9
-0.7
 -0.0
-0.2
 1.9
0.2
 1.0
 -0.8
30 araf A-Raf proto-oncogene, serine/threonine kinase 403063 4.0 2.1
 1.0
0.9
 0.2
-0.2
 1.0
-0.1
 -0.5
-0.5
 0.5
-0.5
 0.4
-1.3
 -0.8
-0.9
 -0.5
 -0.7
 -0.8
-1.3
 0.6
0.6
 0.8
0.4
 2.3
0.3
 -2.2
 0.6
31 pals1a protein associated with LIN7 1, MAGUK family member a 252845 4.0 2.1
 1.8
 3.1
 1.3
 1.5
 0.4
 2.8
 0.8
 0.2
 0.6
 0.6
 -0.1
 -0.7
 1.4
 0.8
 2.0
32 hip1 huntingtin interacting protein 1 793823 4.0 2.1
 2.2
1.1
 -0.1
-0.5
 0.5
-1.3
 0.6
-0.3
 0.9
0.3
 -0.3
-0.3
 2.0
1.0
 2.7
-0.7
 1.2
1.0
 1.1
-1.2
 1.0
-1.0
 0.8
0.4
 0.4
0.3
 -0.3
 1.4
33 ptch1 patched 1 30189 4.0 2.1
 1.7
1.7
 2.3
-1.1
 0.9
-0.4
 2.1
-0.3
 0.5
0.1
 4.0
1.0
 2.2
1.1
 1.8
-0.5
 1.3
-0.1
 1.1
0.6
 -0.1
-0.7
 0.6
0.5
 0.8
-0.8
 -0.6
 0.6
0.5
34 ubr2 ubiquitin protein ligase E3 component n-recognin 2 559136 3.9 2.1
 1.6
-0.2
 -0.1
 -0.4
 1.7
-0.3
 0.6
0.1
 2.8
0.5
 -0.5
-1.2
 -0.5
-1.1
 0.1
-0.4
 0.5
-0.3
 0.2
-1.0
 0.6
-1.6
 0.2
-0.4
 -0.1
 0.5
35 fyco1a FYVE and coiled-coil domain autophagy adaptor 1a 565649 3.9 2.1
 2.4
0.9
 2.0
 0.0
 -0.8
 -1.3
 1.4
 -0.7
 2.0
 0.7
 1.7
 0.9
 -0.5
 -0.4

36 ddx17 DEAD-box helicase 17 556764 3.9 2.1
 0.9
0.4
 0.4
-0.5
 -0.1
-1.0
 -0.1
 -1.1
 0.9
-0.8
 -0.1
-0.8
 1.1
-0.0
 0.1
-0.1
 -0.2
-0.2
 -0.3
-0.4
 -0.9
-0.9
 0.3
-0.0
 3.7
1.8
 -0.3
-1.3
37 sox5 SRY-box transcription factor 5 567413 3.9 2.0
 2.6
1.5
 1.1
 0.2
 0.9
0.4
 1.5
0.3
 1.7
-0.8
 0.8
-0.1
 1.2
0.3
 1.3
0.3
 -0.1
-0.5
 -0.7
-0.7
 0.5
 0.5
-0.4

38 LOC101885270 F-BAR and double SH3 domains protein 2-like 101885270 3.8 2.0
 2.1
1.6
 -1.0
 0.9
 1.3
 -0.8
 0.1
 -1.7
 -0.4
 0.9
 -0.5
 -0.0
 1.1
 -1.0
 3.9
39 ip6k1 inositol hexakisphosphate kinase 1 564478 3.8 2.0
 1.7
0.2
 0.6
-0.5
 1.2
0.9
 -0.6
-0.8
 0.5
0.2
 1.2
-0.3
 0.8
0.7
 2.1
0.7
 0.6
-0.3
 -0.4
-0.4
 0.6
-1.1
 -0.2
-0.3
 0.4
-0.5
 1.3
 0.9
-0.2
40 brd1a bromodomain containing 1a 569574 3.8 2.0
 2.4
1.9
 1.7
0.3
 1.0
0.3
 2.0
1.4
 1.4
-0.1
 1.2
1.1
 1.0
0.9
 2.0
0.7
 0.9
0.7
 0.5
-0.1
 0.9
0.1
 0.8
0.2
 -0.0
-0.5
 -0.6
 1.7
41 scrib scribble planar cell polarity protein 368473 3.8 2.0
 1.5
 0.6
 0.0
 0.3
 -0.5
 1.5
 0.1
 0.2
 0.6

-1.4
 -0.7
 3.0
42 c2cd2 C2 calcium dependent domain containing 2 100332559 3.8 2.0
 2.1
 1.3
 1.5
 -1.3
 0.4
 2.0
 0.1
 0.2
 -0.1
 1.6
 1.2
 1.4
 1.6

43 mib1 MIB E3 ubiquitin protein ligase 1 352910 3.8 2.0
 4.3
1.4

2.0
-0.4
 1.0
-1.0
 2.6
-0.0
 1.2
0.3
 0.3
0.1
 1.5
-0.4
 1.0
-0.3
 0.9
0.2
 1.5
-1.4
 0.6
-1.5
 1.4
-0.1
 -0.9
44 rorca RAR-related orphan receptor C a 559245 3.8 2.0
 1.4
0.1
 0.5
-0.2
 -0.1
-0.5
 1.2
-0.2
 1.0
0.8
 -0.1
-0.3
 0.7
0.4
 0.9
-0.4
 0.1
-0.4
 0.3
-0.2
 -0.6
-1.1
 -0.3
-1.6
 0.9
-0.3
-0.8
45 dlg5a discs, large homolog 5a (Drosophila) 569065 3.8 2.0
 4.6
2.2
 1.1
 1.2
 -0.2
 2.7
 2.9
 -0.6
 0.2
 -1.3
 -0.1
 1.1
 0.3
 1.2
 1.2
 1.2
46 braf B-Raf proto-oncogene, serine/threonine kinase 403065 3.8 2.0
 0.9
 1.3
 -0.4
 1.3
 0.1
 0.3
 0.3
 -1.1
 0.7
 1.0
 -0.7
 0.1
 0.0

47 LOC100331938 activin receptor type-2B-like 100331938 3.7 2.0
 2.3
1.2
 2.2
2.2
 0.6
-1.4
 2.1
1.7
 -0.5
-1.3
 2.4
1.4
 1.3
-0.5
 -0.8
-1.1
 1.0
0.9
 1.4
-0.1
 0.2
-0.7
 1.1
-0.6
 0.9
0.3
 0.0
 0.9
48 magi1a membrane associated guanylate kinase, WW and PDZ domain containing 1a 100319849 3.7 2.0
 -0.0
-1.2
 1.9
 0.3
 -0.2
 1.9
 2.0
 1.0
 0.5
 2.5
 1.2
 -1.6
 0.8
 -0.0
 0.1
 1.1
49 nipbla NIPBL cohesin loading factor a 570900 3.7 2.0
 2.9
1.3
 0.9
 -0.3
 0.0
 -0.3
 -0.4
 -1.3
 0.5
0.2
 -0.3
-1.0
 0.1
 -0.8
 -1.8
 0.9
 -1.1
 -0.1
50 ambra1b autophagy/beclin-1 regulator 1b 559106 3.7 2.0
 0.8
 -0.6
 -0.7
 -0.9
 0.4
 -1.0
 -0.0
 1.0
 1.9
 -0.5
 -0.5
 0.2
 -0.7

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