Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3   vars2   valyl-tRNA synthetase 2, mitochondrial 
 dre-r.3   vars2   valyl-tRNA synthetase 2, mitochondrial 
 dre-u.3   vars1   valyl-tRNA synthetase 1 
 hsa-u.4   VARS2   valyl-tRNA synthetase 2, mitochondrial 
 hsa-u.4   VARS1   valyl-tRNA synthetase 1 
 mmu-u.4   Vars2   valyl-tRNA synthetase 2, mitochondrial 
 mmu-u.4   Vars   valyl-tRNA synthetase 
 rno-u.3   Vars2   valyl-tRNA synthetase 2, mitochondrial 
 rno-u.3   Vars1   valyl-tRNA synthetase 1 
 gga-u.3   107050659   valine--tRNA ligase-like 
 gga-u.3   107049913   valine--tRNA ligase, mitochondrial-like 
 mcc-u.3   VARS2   valyl-tRNA synthetase 2, mitochondrial 
 mcc-u.3   VARS1   valyl-tRNA synthetase 1 
 cfa-u.3   VARS2   valyl-tRNA synthetase 2, mitochondrial 
 cfa-u.3   VARS1   valyl-tRNA synthetase 1 
 dme-u.3   ValRS-m   Valyl-tRNA synthetase, mitochondrial 
 dme-u.3   ValRS   Valyl-tRNA synthetase 
 cel-u.3   glp-4   Valine--tRNA ligase 
 cel-u.3   vars-1   Valyl-tRNA synthetase 
 sce-u.3   VAS1   valine--tRNA ligase 
 spo-u.3   clp1   Cdc14 family protein phosphatase Clp1 

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Top 50 coexpressed genes to vars2 (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre280   Valine, leucine and isoleucine degradation  4 57 4.94
 dre3010   Ribosome  4 131 3.52
 dre1212   Fatty acid metabolism  3 73 3.11
 dre640   Propanoate metabolism  2 31 2.58
 dre970   Aminoacyl-tRNA biosynthesis  2 43 2.30

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dre:vars2 (valyl-tRNA synthetase 2, mitochondrial) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dre-u.3
for
vars2
dre-r.3
for
vars2
dre-u.3
for
vars1
hsa-u.4
for
VARS2
hsa-u.4
for
VARS1
mmu-u.4
for
Vars2
mmu-u.4
for
Vars
rno-u.3
for
Vars2
rno-u.3
for
Vars1
gga-u.3
for
107050659
gga-u.3
for
107049913
mcc-u.3
for
VARS2
mcc-u.3
for
VARS1
cfa-u.3
for
VARS2
cfa-u.3
for
VARS1
dme-u.3
for
ValRS-m
dme-u.3
for
ValRS
cel-u.3
for
glp-4
cel-u.3
for
vars-1
sce-u.3
for
VAS1
spo-u.3
for
clp1
1 mtif2 mitochondrial translational initiation factor 2 556465 6.7 3.5
 2.9
 1.8
 1.2
 3.0
 -0.2
 3.0
 1.4
 0.2
 -0.0
 1.6
 -0.2
 0.3
 0.0
 5.4
 3.0
 2.2
 9.0
 0.9
2 drosha drosha ribonuclease III 567505 6.2 3.3
 3.5
 1.5
 3.2
 1.7
 1.7
 3.0
 1.4
 -0.8
 2.3
 3.4
 0.9
 2.2
 2.5
 2.0
 2.1
 0.6
 3.0
 -0.8
 -0.8
3 aars2 alanyl-tRNA synthetase 2, mitochondrial (putative) 792787 6.0 3.1
 5.8
1.9
 6.4
1.5
 5.8
3.1
 5.5
0.3
 5.1
3.2
 5.9
-1.1
 5.8
3.5
 2.9
1.5
 0.9
0.3
 2.5
1.4
 4.8
1.2
 2.4
0.3
 3.3
2.0
 0.8
 10.4
 7.0
1.6
 9.0
2.7
 7.9
4 ptcd3 pentatricopeptide repeat domain 3 553325 5.9 3.1
 2.5
 2.7
 0.8
 2.7
 -1.2
 3.1
 1.3
 -0.6
 0.9
 1.5
 1.1
 3.0
 1.7
 3.9
 3.8
 2.0
 5.9

5 pex1 peroxisomal biogenesis factor 1 793906 5.6 2.9
 2.7
 1.1
 -0.2
 1.5
 -0.5
 1.2
 -1.3
 -0.2
 -1.0
 2.9
 -1.4
 1.6
 -0.3
 1.7
 1.1

0.8
 0.4
6 acsf3 acyl-CoA synthetase family member 3 562292 5.5 2.9
 2.6

6.2
 2.6
 2.8
 1.5
 1.4
 1.7
 2.1
 1.5
 2.2
 0.6
 0.5
-0.1
 1.4
-0.8
 0.9
0.4
 1.7
0.5
 0.9
 0.7
0.6
7 nudcd1 NudC domain containing 1 553654 5.4 2.9
 1.9
 0.6
 2.1
 0.8
 3.7
 0.7
 1.5
 1.1
 0.9
 0.1
 0.5
 0.2
 1.0
 2.6
 0.0
 -0.4
 2.6

8 cars2 cysteinyl-tRNA synthetase 2, mitochondrial 555187 5.4 2.8
 1.1
 1.6
 1.9
 2.6
 0.9
 3.0
 0.2
 0.4
 1.3
 0.9
 2.2
 1.3
 3.4
 4.9
 2.3



9 coq3 coenzyme Q3 methyltransferase 436893 5.4 2.8
 -0.9
 0.2
 2.1
 1.8
 -0.1
 1.4
 1.4
 0.6
 0.8
 0.7
 1.2
 1.2
 -0.1
 2.1
 -0.1
 -0.0
 1.1
 0.0
 1.6
10 abcb8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 548340 5.2 2.7
 1.3
 4.5
 2.9
 4.7
 2.0
 6.9
 1.1
 7.5
 4.6
 4.7
 4.7
 5.1
 1.9
 0.9
 1.4
 1.5
 2.3

11 mipepa mitochondrial intermediate peptidase a 100005953 5.2 2.7
 4.0
1.1
 0.4
 3.1
 3.2
 1.5
 2.5
 -0.1
 1.6
 -1.2
 2.0
 0.3
 -0.3
 1.3
 2.3
 4.4
 0.3
 4.7
 0.0
 -0.2
12 acad8 acyl-CoA dehydrogenase family, member 8 394130 5.1 2.7
 1.1
 0.9
 0.9
 2.1
 -1.5
 3.6
 -0.4
 1.0
 1.1
 1.0
 1.0
 0.5
 0.1

1.7
 0.3

13 lrpprc leucine-rich pentatricopeptide repeat containing 557195 5.0 2.6
 5.5
 1.1
 4.1
 3.0
 3.6

3.3
 1.2
 2.0
 3.5
 0.9
 3.0
 4.0
 6.4



14 timm21 translocase of inner mitochondrial membrane 21 560369 4.9 2.6
 0.1
 1.0
 0.1
 3.3
 -1.6
 2.4
 0.0
 1.6
 -0.3
 -0.1
 -0.3
 0.2
 -0.3
 2.2
 0.3
 1.3
 3.3
 -0.1
 0.6
15 si:ch211-198n5.11 si:ch211-198n5.11 100004018 4.9 2.6
 0.9
0.4
 -0.3
 2.7
 2.0
 0.8
 2.0
 -0.1
 0.8
-0.3
 -0.2
-1.0
 1.3
 1.9
 1.3
 2.4
 1.2
 2.6
 4.8
 3.3

16 uvrag UV radiation resistance associated gene 394044 4.8 2.5
 0.4
 -1.6
 0.4
 0.7
 1.3
 -1.8
 -0.8
 0.3
 -0.9
 0.1
 -0.6
 -2.3
 -0.7
 0.7
 0.0
 0.3
-0.6
 0.7
-0.0
-0.1
17 mrpl9 mitochondrial ribosomal protein L9 572170 4.8 2.5
 2.3
 -0.3
 2.2
 0.8
 -0.3
 0.7
 -0.5
 1.9
 1.1
 0.1
 0.6
 0.9
 2.2
 0.9
 1.8
 2.2
 4.1
-0.6
18 mrps9 mitochondrial ribosomal protein S9 751681 4.7 2.5
 2.6
 1.1
 1.4
 2.0
 0.3
 3.2
 0.8
 0.3
 0.3
 -1.5
 1.0
 0.4
 -0.0
 0.1
 1.6
 2.9
 5.7
 -0.2
 -1.5
19 ppp1r11 protein phosphatase 1, regulatory (inhibitor) subunit 11 550290 4.7 2.5
 -1.0
 1.2
 1.7
 -1.0
 0.3
 0.7
 -1.1

0.1
 0.9
 0.2
 1.9
 2.2
0.4
 0.4
-0.8
 0.3
0.2
 -0.5
-2.0
1.6
20 pdss2 prenyl (decaprenyl) diphosphate synthase, subunit 2 436624 4.7 2.5
 2.4
 1.1
 2.7
 3.9
 -0.7
 2.1
 0.7
 0.8
 -1.3
 1.7
 -0.1
 0.7
 -0.1
 1.6
 -0.5



21 aifm1 apoptosis inducing factor mitochondrion associated 1 373125 4.6 2.4
 3.2
 0.6
 2.0
 2.2
 0.2
 3.0
 1.6
 1.2
 0.3
 1.9
 4.2
 -0.0
 1.6
 7.3
 1.7
 4.1
 5.3

22 rpap1 RNA polymerase II associated protein 1 570666 4.6 2.4
 3.9
 4.3
 6.0
 4.9
 3.9
 3.9
 2.9
 0.0
 0.9
 4.0
 3.7
 3.0
 2.2
 1.4
 1.8

-0.3
23 rbfa ribosome binding factor A 100037330 4.6 2.4
 -0.1
 1.8
 2.2
 3.0
 0.9
 4.1
 -0.2
 0.5
 -0.8
 1.6
 1.8
 2.3
 2.1
 0.7
 -1.1



24 twnk twinkle mtDNA helicase 100330448 4.6 2.4
 1.8
 1.3
 3.5
 2.9
 0.9
 2.8
 2.0
 3.8
 2.2
 2.0
 2.5
 2.0
 2.4
 1.5
 2.4
 -0.3
 -0.4

25 fan1 FANCD2 and FANCI associated nuclease 1 565458 4.5 2.4
 0.6
 2.0
 0.8
 2.5
 -0.9
 2.4
 -0.5
 1.2
 0.6
 4.0
 -0.2
 -0.1
 -0.8

-0.5
 3.0

26 acss2 acyl-CoA synthetase short chain family member 2 436914 4.4 2.3
 1.0
0.3
 0.7
0.7
 0.4
0.0
 1.1
1.0
 1.1
-0.3
 1.8
-0.0
 0.2
-0.6
 1.0
0.5
 1.0
-0.3
 1.8
0.8
 0.5
0.1
 0.4
-1.1
 -0.3
-0.7
 1.0
 1.1
 1.7
 -0.4
 3.4
-1.0
 0.9
-0.2
27 dnajc11a DnaJ (Hsp40) homolog, subfamily C, member 11a 322953 4.4 2.3
 2.9
0.8
 1.8
 4.0
 2.0
 1.1
 0.9
 5.1
 0.3
 0.2
 2.8
 5.3
 1.7
 3.3
 6.5
 4.2
 4.0
 5.9

28 mto1 mitochondrial tRNA translation optimization 1 100009640 4.4 2.3
 1.4
 0.4
 1.8
 3.0
 0.3
 1.7
 1.2
 1.5
 -0.8
 -0.1
 1.3
 3.8
 4.1
 2.9
 3.2
 0.6
 6.7
 0.4
 0.6
29 mks1 MKS transition zone complex subunit 1 556706 4.4 2.3
 -0.1
 3.0
 2.7
 3.2
 0.3
 2.6
 -1.0
 1.6
 1.4
 2.9
 1.7
 -0.1
 -0.6





30 atpaf2 ATP synthase mitochondrial F1 complex assembly factor 2 560253 4.4 2.3
 0.3
 0.2
 0.9
 1.5
 0.8
 1.4
 0.1
 1.0
 0.0
 0.2
 2.4
 1.7
 0.1
 0.4
 1.0
 1.8
 3.8
 -0.7
 -0.3
31 prorp protein only RNase P catalytic subunit 555630 4.3 2.3
 2.3
 1.0
 1.7
 1.9
 1.1
 2.8
 0.0
 2.0
 -0.4
 1.5
 2.3
 -0.6
 -0.7
 2.2
 1.3



32 mrps22 mitochondrial ribosomal protein S22 556778 4.3 2.3
 1.6
 -0.7
 -0.2
 0.8
 -0.8
 2.0
 1.8
 0.2
 -0.2
 -1.0
 -0.2

1.7
 2.2
 4.1
 5.6
1.0
33 dhx29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 553505 4.3 2.3
 3.6
 -1.2
 1.1
 1.2
 1.6
 0.3
 1.8
 1.6
 0.1
 -0.0
 0.0
 -0.7
 1.7





34 fastkd3 FAST kinase domains 3 100003734 4.3 2.3
 -0.9
 -0.1
 -0.4
 -0.7
 -0.9
 1.4
 -0.6
 0.3
 1.4
 1.2
 0.1
 0.9
 0.9





35 topbp1 DNA topoisomerase II binding protein 1 407679 4.3 2.3
 2.2
 0.4
 -0.7
 1.1
 3.3
 0.6
 0.2
 0.1
 1.7
 0.3
 0.3
 1.7
 0.9
 0.9
 0.6

-1.5
 -1.6
36 anapc2 anaphase promoting complex subunit 2 100318335 4.3 2.3
 1.7
 3.1
 2.3
 0.5
 2.6
 1.8
 1.4
 3.5
 1.4
 3.0
 3.3
 2.5
 2.1
 2.9
 -0.5
 1.5
 4.1
 -0.5
 -0.6
37 orc3 origin recognition complex, subunit 3 334315 4.3 2.3
 2.3
 -1.1
 0.5
 2.2
 -1.1
 1.0
 1.0
 1.4
 0.2
 0.7
 1.2
 0.1
 0.3





38 mrpl19 mitochondrial ribosomal protein L19 445150 4.2 2.2
 0.9
 0.6
 2.1
 1.1
 0.4
 2.0
 2.3
 -0.7
 -1.0
 0.9
 0.6
 -0.0
 0.8
 2.3
 1.0
 2.4
 2.3
 0.1
 0.6
39 susd2 sushi domain containing 2 793335 4.2 2.2
 0.0
 0.5
 -0.3
 -0.0
 0.2
 0.2
 0.7
 0.1
 -0.4
 -0.2
 1.4
 0.7
 0.1
 0.9
 -0.1
 -0.3
 0.4

40 mrps5 mitochondrial ribosomal protein S5 562703 4.2 2.2
 2.0
 2.5
 1.4
 3.4
 0.2
 2.1
 3.5
 -1.2
 0.6
 2.1
 3.2
 1.2
 1.5
 -0.0
 -0.5
 1.3
 3.8
 -0.1
41 fastkd5 FAST kinase domains 5 569940 4.2 2.2
 0.4
 -0.3
 0.0
 0.7
 -1.6
 0.1
 0.2
 -0.3
 -0.9
 0.7
 1.9
 1.6
 2.0
 2.9
0.9
 2.5
1.0



42 si:ch1073-143l10.2 si:ch1073-143l10.2 565165 4.2 2.2


















43 ap5z1 adaptor related protein complex 5 subunit zeta 1 100537934 4.1 2.2
 0.8
 1.5
 -0.1
 2.7
 1.1
 3.2
 0.1
 0.3
 1.7
 1.4
 1.0
 1.9
 0.6





44 opa1 OPA1 mitochondrial dynamin like GTPase 492332 4.1 2.2
 2.2
 0.2
 1.8
 2.9
 0.0
 1.2
 1.6
 0.2
 -0.2
 0.4
 1.4
 1.0
 -0.2
 2.1
 3.7
 3.4
 6.3

45 hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 393105 4.1 2.2
 1.9
 0.5
 0.8
 1.6
 -0.5
 0.9
 -1.0
 0.3
 -0.4
 0.8
 0.3
 0.1
 -0.8
 -1.2
 0.0
 -0.2
-0.3
 0.3
-0.2
 -0.9
 0.1
46 ints8 integrator complex subunit 8 553794 4.1 2.2
 2.2
 -0.7
 0.5
 -0.7
 -0.9

1.0
 -0.0
 0.5
 -1.3
 1.5
 0.1
 0.8
 2.3



47 fxn frataxin 556389 4.1 2.2
 -0.3
 0.5
 1.5
 0.6
 1.5
 0.5
 1.0
 -0.2
 -0.1
 0.8
 1.4
 1.1
 2.6
 2.3
 -1.0
 0.2
 0.8
 0.4
 -1.0
48 hadhab hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b 793834 4.1 2.2
 2.2
1.8
 -0.1
 1.3
 0.9
 1.0
 1.7
 1.4
 3.7
 0.9
 1.2
 1.7
 0.3
 -1.6
 0.5
 1.6
 1.2
-0.4
 0.9
-0.7
0.3
49 thap7 THAP domain containing 7 100006965 4.1 2.1
 0.0
 1.0
 -1.1
 0.0
 -0.4
 -0.0
 1.0
 0.9
 2.1
 0.8
 0.8
 1.2
 1.8





50 wdr6 WD repeat domain 6 100004270 4.1 2.1
 3.2
 3.7
 3.0
 3.0
 1.2
 1.9
 -0.4
 1.6
 6.1
 4.6
 1.6
 1.2
 2.2
 3.0
 3.3
 2.8
 7.5
 1.8
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