Orthologous genes in OrthoFinder**

Species Gene Description
 cfa-u.3   HPD   4-hydroxyphenylpyruvate dioxygenase 
 cfa-r.3   HPD   4-hydroxyphenylpyruvate dioxygenase 
 cfa-m.4   HPD   4-hydroxyphenylpyruvate dioxygenase 
 hsa-u.4   HPD   4-hydroxyphenylpyruvate dioxygenase 
 mmu-u.4   Hpd   4-hydroxyphenylpyruvic acid dioxygenase 
 rno-u.3   Hpd   4-hydroxyphenylpyruvate dioxygenase 
 mcc-u.3   HPD   4-hydroxyphenylpyruvate dioxygenase 
 gga-u.3   HPD   4-hydroxyphenylpyruvate dioxygenase 
 dre-u.3   hpdb   4-hydroxyphenylpyruvate dioxygenase b 
 dre-u.3   hpda   4-hydroxyphenylpyruvate dioxygenase a 
 dme-u.3   Hpd   4-hydroxyphenylpyruvate dioxygenase 
 cel-u.3   hpd-1   4-hydroxyphenylpyruvate dioxygenase 

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Top 50 coexpressed genes to HPD (cfa-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 cfa4610   Complement and coagulation cascades  11 66 7.17
 cfa5171   Coronavirus disease - COVID-19  6 190 4.48
 cfa4979   Cholesterol metabolism  5 44 6.53
 cfa3320   PPAR signaling pathway  5 69 5.54
 cfa5150   Staphylococcus aureus infection  4 58 4.43

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cfa:HPD (4-hydroxyphenylpyruvate dioxygenase) External Links;


Show/Hide Columns:        
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

cfa-u.3
for
HPD
cfa-r.3
for
HPD
cfa-m.4
for
HPD
hsa-u.4
for
HPD
mmu-u.4
for
Hpd
rno-u.3
for
Hpd
mcc-u.3
for
HPD
gga-u.3
for
HPD
dre-u.3
for
hpdb
dre-u.3
for
hpda
dme-u.3
for
Hpd
cel-u.3
for
hpd-1
1 NNMT nicotinamide N-methyltransferase 489396 6.2 1.9
 5.0
 1.8
1.1
 2.7
2.5
 1.3
0.7
 2.3
1.0
 0.1
 -1.1
 -0.1
1.4
1.2
2 APOH apolipoprotein H 403945 5.0 1.1
 4.7
 3.8
 7.5
 2.6
 1.4
 3.9
 1.4
 -1.2
 1.5
3 APOA1 apolipoprotein A1 479427 5.0 0.7
 5.1
 2.4
 5.4
 0.9
 1.2
 1.1
 0.9
 -1.6

4 ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 491368 4.9 0.9
 4.9
 4.1
 3.0
 2.7
 1.4
 2.9
 0.8
0.2
 3.7
-0.7

5 LOC489397 nicotinamide N-methyltransferase 489397 4.8 1.5
 3.8
 1.8
1.1
 2.7
2.5
 1.3
0.7
 2.3
1.0
 0.1
 -1.1
 -0.1
1.4
1.2
6 APOC3 apolipoprotein C3 442970 4.7 1.5
 3.8
 3.7
 9.0
 4.1
 1.0
 3.3



7 HPX hemopexin 610982 4.7 1.5
 3.8
 2.7
 4.6
 1.0
 1.2
 1.9
 -0.9
-1.1
 3.5
3.5

8 VTN vitronectin 480621 4.7 0.6
 4.9
 4.6
 2.7
 1.0
 1.1
 3.2
 0.0
-0.1
 4.6
2.4

9 LOC479668 haptoglobin-like 479668 4.5 1.1
 4.1
 3.0
2.9
 1.3
 1.0
 0.6
0.1
-2.5
 0.9

10 APOA2 apolipoprotein A2 478982 4.5 1.3
 3.8
 4.0
 7.0
 2.1
 0.7
 4.8



11 KNG1 kininogen 1 478666 4.4 0.5
 4.7
 3.7
 7.5
3.7
 2.0
1.4
 1.0
 3.1
 0.0
-0.7
 3.5
-0.6
0.8
0.6
12 CYP2D15 cytochrome P450 2D 415120 4.3 1.4
 3.4
 0.0
 10.2
8.5
 3.5
1.4
 0.7
-0.2
 0.3


0.4
13 BHMT betaine--homocysteine S-methyltransferase 479171 4.1 1.2
 3.4
 4.8
3.0
 9.0
7.8
 4.4
3.0
 1.3
0.4
 1.7
 1.1
 1.2

14 FGB fibrinogen beta chain 475472 4.1 0.5
 4.3
 2.2
 6.0
 2.4
 2.4
 3.2
 -1.5
 4.2

15 LOC481722 complement C4-A 481722 4.0 0.9
 3.7
0.5
0.1
 -0.3
-0.7
 0.7
0.7
 1.6
 -1.2
-1.3
 1.8
1.1

16 FGG fibrinogen gamma chain 475474 3.8 0.6
 3.9
 3.3
 5.3
 1.6
 1.5
 3.0
 -1.2
 4.7

17 GC GC vitamin D binding protein 475172 3.7 0.2
 4.3
 2.9
 6.4
 1.6
 1.4
 2.2
 1.4
 7.7

18 TMEM176A transmembrane protein 176A 475535 3.7 1.3
 2.8
 0.5
 -0.7
 0.2
 0.1




19 CFH complement factor H 478952 3.7 0.8
 3.4
 3.3
2.8
 6.3
3.6
 1.0
0.5
 2.3
1.1
 0.5
 -0.8
-0.8
 5.3
2.8

20 ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 476590 3.6 1.0
 3.1
 4.4
 7.0
 1.3
 0.9




21 AGTR1 angiotensin II receptor type 1 403836 3.6 1.4
 2.6
 1.2
 1.9
 0.2
 0.8
 -0.0
 1.2
 -0.8

22 A1CF APOBEC1 complementation factor 477581 3.5 0.4
 3.8
 2.5
 2.7
 0.5
 0.6
 1.3
 0.1
 3.4

23 C3 complement C3 476728 3.5 1.5
 2.3
 2.6
 1.7
 0.6
 2.1
 1.8
 0.2
0.1
 4.7
3.5

24 ALDOB aldolase, fructose-bisphosphate B 474787 3.5 0.6
 3.5
 3.0
-0.3
 6.8
0.4
 3.8
0.4
 0.6
 2.6
1.4
 2.0
0.2
 2.6
-0.4
 1.7
0.2
 3.1
1.8
25 LOC448801 mastin 448801 3.5 1.1
 2.8
0.3
1.6
0.9




26 SFRP5 secreted frizzled related protein 5 486826 3.5 1.0
 2.9
 0.3
0.1
 -0.1
-0.6
 0.3
-1.0
 0.5
-1.0
 -0.3
-0.6
 1.7
1.1
 0.4
-0.3
-0.0
27 SLC27A2 solute carrier family 27 member 2 478298 3.4 0.4
 3.7
 1.1
0.4
 3.5
0.6
 2.0
1.2
 1.2
0.7
 1.9
0.6
 0.9
0.9
 3.3
2.0
 1.0
0.2
 2.3
-0.1
28 SERPINA4 serpin family A member 4 490840 3.4 1.2
 2.6
 3.6
2.6
 1.8




29 SERPINA3 serpin family A member 3 480425 3.4 0.8
 3.1
 1.6
 8.6
3.2
 1.7
1.0
 -0.2




30 SERPINC1 serpin family C member 1 480066 3.4 0.5
 3.5
 3.7
 6.0
 3.2
 1.1
 4.7
 0.2
 4.0

31 CLEC4G C-type lectin domain family 4 member G 484999 3.3 0.7
 3.2
 0.9
 3.2
 -0.0
 0.7



1.7
32 RGN regucalcin 480893 3.3 0.9
 2.9
 2.7
 5.7
 1.7
 1.1
 1.6
 0.3
 1.5
 3.9
1.2
33 APOC2 apolipoprotein C2 442969 3.3 0.7
 3.2

2.8
 1.0
 3.0
 -1.5
 3.8

34 PCK1 phosphoenolpyruvate carboxykinase 1 403560 3.3 1.6
 1.9
 2.7
1.3
 7.2
-0.6
 2.1
0.3
 0.6
0.2
 1.1
 2.0
0.7
 2.3
0.8
 -0.2
 4.1
1.8
35 TMEM176B transmembrane protein 176B 610914 3.3 1.5
 2.1
 0.6
 -0.4
 -0.4
 -0.2




36 IL3RA interleukin 3 receptor subunit alpha 609293 3.3 0.6
 3.2
 1.1
-0.9
 -1.0
-1.0
 1.0
-0.7
0.7
-0.1



37 CES1 carboxylesterase 1 403643 3.3 1.1
 2.5
 3.5
2.7
 10.9
9.3
 1.9
1.7
 0.5
0.4
 2.4
1.5
 1.4
0.9
 4.3
3.1
 3.1
2.6
 3.8
2.5
38 C6 complement C6 479348 3.2 0.6
 3.2
 2.1
 1.1
 0.2
 1.2
 0.5
 -0.9
-2.1
 0.3
-0.5

39 IGFBP4 insulin like growth factor binding protein 4 608158 3.2 1.2
 2.3
 1.2
 1.5
 0.5
 0.9
 1.4
 0.7
0.2
 1.8
1.2

40 DIO1 iodothyronine deiodinase 1 403635 3.2 1.0
 2.6
 2.5
 3.8
 -0.4
 0.4
 2.2
 0.4
 1.8

41 CYP2E1 cytochrome P450 family 2 subfamily E member 1 415128 3.2 1.0
 2.6
 1.7
1.6
 8.6
8.6
 6.4
2.9
 2.3
2.0
 1.4
1.4
 0.4
0.2
 0.9
0.3
2.6
42 FCER1A Fc fragment of IgE receptor Ia 478970 3.1 0.8
 2.8
 0.4
0.4
 0.1
0.1
 0.9
0.7
 0.5
0.1
 1.9
1.0



43 HAAO 3-hydroxyanthranilate 3,4-dioxygenase 611728 3.1 1.0
 2.6
 2.3
 3.8
 2.7
 2.8
 0.5
 1.2
 1.3
2.1
44 F10 coagulation factor X 476993 3.1 0.1
 3.7
 2.9
 2.1
 2.4
 2.2
 1.4
 0.2
 2.1

45 TCN2 transcobalamin 2 486355 3.1 1.4
 2.0
 1.1
 0.5
 0.9
 0.4
 1.7
 0.5
 0.7

46 SLC22A1 solute carrier family 22 member 1 484068 3.1 1.2
 2.3
 3.4
2.2
 5.1
3.6
 1.5
1.3
 1.7
1.3
 1.3
1.3
 2.6
1.8
 2.9
0.9
 2.7
1.1
 2.7
2.0
47 ASS1 argininosuccinate synthase 1 480693 3.1 1.0
 2.5
 2.1
 3.1
 3.5
 0.7
 0.9
 0.2
 -1.0
 0.2
48 PROC protein C, inactivator of coagulation factors Va and VIIIa 476104 3.1 0.6
 3.0
 2.0
 7.4
 2.5
 0.5
 2.2
 -0.7
 4.7

49 RAB3IL1 RAB3A interacting protein like 1 612267 3.0 1.6
 1.6
 -0.4
 0.9
-0.1
 0.8
-0.9
 1.0
0.1
 -0.6
-1.1
 -0.4
-0.6
 -0.3
-1.3
-0.5
50 FAM167B family with sequence similarity 167 member B 611831 3.0 0.2
 3.5
 0.6
 1.2
 -0.0
 1.1
 0.8
 0.4
 -0.1

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