Orthologous genes in OrthoFinder**

Species Gene Description
 cfa-u.3  PFKFB1  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 cfa-r.3  PFKFB1  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 cfa-m.4  PFKFB1  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 cfa-u.3  PFKFB4  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 
 cfa-u.3  PFKFB2  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 cfa-u.3  PFKFB3  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 
 hsa-u.4  PFKFB2  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 hsa-u.4  PFKFB3  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 
 mmu-u.4  Pfkfb2  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 mmu-u.4  Pfkfb1  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 mmu-u.4  Pfkfb4  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 
 rno-u.3  Pfkfb3  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 
 rno-u.3  Pfkfb2  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 mcc-u.3  PFKFB4  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 
 mcc-u.3  PFKFB2  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 mcc-u.3  PFKFB3  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 
 gga-u.3  PFKFB4  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 
 gga-u.3  PFKFB1  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 gga-u.3  PFKFB2  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 dre-u.3  pfkfb2b  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b 
 dre-u.3  pfkfb4a  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a 
 dme-u.3  Pfrx  6-phosphofructo-2-kinase 
 cel-u.3  pfkb-1.1  6-phosphofructo-2-kinase 
 cel-u.3  pfkb-1.2  Fructose-2,6-bisphosphatase 
 sce-u.3  YLR345W  bifunctional fructose-2,6-bisphosphate 2-phosphatase/6-phosphofructo-2-kinase 
 sce-u.3  FBP26  fructose-2,6-bisphosphatase 

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Top 50 coexpressed genes to PFKFB1 (cfa-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 cfa3320   PPAR signaling pathway  7 69 7.05
 cfa4923   Regulation of lipolysis in adipocytes  5 47 6.39
 cfa4080   Neuroactive ligand-receptor interaction  5 146 3.96
 cfa4920   Adipocytokine signaling pathway  4 62 4.32
 cfa4152   AMPK signaling pathway  4 113 3.31

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cfa:PFKFB1 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1) External Links;


Show/Hide Columns:        
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID
Other ID LINK Target Reference

cfa-u.3
for
PFKFB1


cfa-r.3
for
PFKFB1


cfa-m.4
for
PFKFB1


cfa-u.3
for
PFKFB4


cfa-u.3
for
PFKFB2


cfa-u.3
for
PFKFB3


hsa-u.4
for
PFKFB2


hsa-u.4
for
PFKFB3


mmu-u.4
for
Pfkfb2


mmu-u.4
for
Pfkfb1


mmu-u.4
for
Pfkfb4


rno-u.3
for
Pfkfb3


rno-u.3
for
Pfkfb2


mcc-u.3
for
PFKFB4


mcc-u.3
for
PFKFB2


mcc-u.3
for
PFKFB3


gga-u.3
for
PFKFB4


gga-u.3
for
PFKFB1


gga-u.3
for
PFKFB2


dre-u.3
for
pfkfb2b


dre-u.3
for
pfkfb4a


dme-u.3
for
Pfrx


cel-u.3
for
pfkb-1.1


cel-u.3
for
pfkb-1.2


sce-u.3
for
YLR345W


sce-u.3
for
FBP26

1 ADIPOQ adiponectin, C1Q and collagen domain containing 403625 6.7 2.6
4.7
0.9
-0.0
1.7
-0.6
0.6
-1.0
1.9
0.5
0.9
0.0
-2.2
-1.0
-0.5
-0.1
0.0
-0.2







2 GPD1 glycerol-3-phosphate dehydrogenase 1 607942 6.6 2.0
5.3
1.4
0.3
1.2
-0.1
1.2
-1.4
1.6
0.6
0.3
-0.4
1.5
-0.4
1.4
-0.0
0.6
-0.1
2.2
1.8
2.0
-1.3
-2.1
1.9
0.4
3.8
0.9
1.2
1.0
0.8
-0.0
0.5
0.4
0.9
0.6
3.1
-1.3
2.0
-1.7
3.4
-1.7
0.4
-1.1
-1.1
-1.2
3 CIDEC cell death inducing DFFA like effector c 484662 6.6 2.9
4.2
0.5
0.1
-0.3
-0.6
2.2
1.2
-0.6
-1.1
0.5
-0.2
0.5
0.3
2.8
0.6
0.5
0.1
1.5
0.3
0.1
-0.5
-0.3
-0.8
0.4
0.2
-0.5
-0.5
3.5
1.1
1.2
-0.1
-0.3
-1.2
-0.4
-0.4
1.5
0.1
0.0
-0.1




4 PCK1 phosphoenolpyruvate carboxykinase 1 403560 6.2 3.4
3.1
0.5
-0.3
-0.4
-0.7
1.1
-0.3
0.1
0.0
1.0
-1.1
0.0
-1.3
2.6
-0.5
1.2
-1.0
0.5
-0.7
-0.3
-0.9
0.4
0.1
-0.3
-0.9
0.2
-1.7
0.9
0.5
0.4
-0.3
-1.0
0.2
-0.1
0.0
4.8
-0.1
-0.2
-0.8


5 APOC3 apolipoprotein C3 442970 6.0 2.5
3.9
0.3
-0.3
0.4
-1.7
-1.6
-1.3
0.9
-0.3
-0.1
-0.5
0.7
-1.4
-1.5
-0.2
-0.1
-0.5







6 TMEM182 transmembrane protein 182 611413 6.0 3.0
3.2
-0.0
-0.7
1.1


-0.6
1.7
-0.2
-0.2
0.3



-0.2
0.1
0.4
1.4
0.7





7 TECRL trans-2,3-enoyl-CoA reductase like 475157 5.9 3.2
3.0
0.5
0.4
-0.1
-0.7
0.5
-0.3
-0.1
-1.2
-0.3
-0.5
0.8
-0.9
1.5
-0.8
0.3
-1.0
0.2
-1.7
0.4
-0.3
-0.9
-0.9
0.8
0.1
-0.1
2.2
0.7
0.6
-0.0
0.7
-0.3
-0.2
-0.6
0.8
1.2
0.8
-0.2
-1.1
8 PLIN1 perilipin 1 100856637 5.9 3.2

-1.4
0.1
0.2
-1.0
0.6
-0.4
0.9
-0.1
1.7
1.0
-1.4
1.1
-2.2
-0.1
0.8
1.4


0.9




9 SLC22A1 solute carrier family 22 member 1 484068 5.6 2.4
3.6
1.0
1.0
1.8
1.5
1.8
0.6
3.5
2.0
0.8
0.6
2.4
0.7
2.7
1.0
1.5
1.5
1.0
0.9
1.1
1.1
3.2
1.1
0.5
0.3
1.6
0.9
2.6
1.3
1.0
0.9
1.3
1.1
1.6
1.1
1.1
1.0
1.7
1.6
2.3
1.9
2.3
1.4


10 LOC479668 haptoglobin-like 479668 5.4 2.6
3.2
-0.5
0.2
0.4
0.3
-0.3
0.9
0.1
-0.3
1.6
0.9
-0.1
-0.7
-0.4
-1.2
0.6
0.3
0.0
-0.9



0.2
-0.2





11 MTARC1 mitochondrial amidoxime reducing component 1 488601 5.3 2.2
3.6
-0.4
-1.3
0.2
-0.8
1.1
-1.4
1.8
1.4
0.2
-0.2
0.1
-1.2
3.1
0.4
-0.6
-0.7
0.3
-0.9
-1.1
-1.5
2.4
-0.6
0.2
-0.2
0.1
0.1
-2.4
0.9
0.6
0.8
-0.4
0.1
0.4
0.3
1.6
0.8


12 AQP7 aquaporin 7 474742 5.2 1.0
5.0
-0.4
1.1
1.0
0.7
0.6



0.5
0.4
0.8
0.6
-1.4










13 FGG fibrinogen gamma chain 475474 4.8 2.9
2.0
-1.3
-0.1
0.1
-0.8
-0.3
0.3
0.9
-0.3
0.9
0.5
-1.9
-0.6
-1.4
-1.2
-0.1
-0.5
0.4
0.0





14 G6PC1 glucose-6-phosphatase catalytic subunit 1 403492 4.8 1.8
3.5
1.4
0.1
0.0
-0.2
0.9
0.2
-0.6
-0.8
-0.5
-1.0
-0.3
-0.5
0.3
0.2
0.9
-0.2
-0.0
-0.5
0.1
0.0
0.7
-0.6
-1.0
-1.2
0.4
-0.6
0.5
0.1
1.0
0.1
0.3
-0.3
-0.4
-0.5
-0.3
-0.4
-0.6




15 LOC100856533 alcohol dehydrogenase E chain 100856533 4.7 2.5

0.3
-0.1
0.4
-0.1
-0.5
-1.6
-0.4
-0.5
0.0
-0.3
0.9
0.2
1.1
1.0
0.1
0.1
-0.1
-0.3
0.1
-0.4
0.3
-0.8
0.8
-0.3
1.2
0.4
-0.6
-0.7
0.3
-0.3
0.1
0.1
0.1
-0.3
0.7
4.1
1.5
0.2
-0.3
16 ACVR1C activin A receptor type 1C 488361 4.5 1.5
3.5
1.2
0.2
0.7
0.3
1.2
0.5
2.3
2.0
2.8
1.7
1.3
0.5
1.5
-0.1
2.8
2.5
4.5
1.5
1.6
1.3
1.5
0.4
1.7
0.2
1.3
0.5
2.6
1.1
1.1
0.5
0.6
0.4
1.8
0.7
2.2
1.4
1.5
0.3
1.9
0.6
0.3
-0.3


17 PLIN4 perilipin 4 491467 4.5 1.4
3.6
1.1
1.3
1.6
1.1
1.6
1.1
2.7
-0.4
2.6
0.1
-1.7
-0.2
-0.5










18 DGAT2 diacylglycerol O-acyltransferase 2 485185 4.4 1.9
2.9
1.2
0.4
1.7
0.5
1.5
-0.2
0.2
1.4
0.2
-0.8
2.8
1.8
1.8
-0.0
2.1
0.8
0.2
-0.1
1.6
1.5
0.7
0.4
0.5
-0.1
1.2
0.4
1.9
0.9
1.1
0.7
0.6
0.6
1.5
-0.7
-0.7
-0.8
2.4
1.1
3.4
1.3
2.7
1.5
19 AGT angiotensinogen 403783 4.4 2.4
2.1
-0.1
1.0
1.1
0.8
0.0
-0.4
0.4
-1.1
0.4
-0.8
-1.7
0.4
0.0
-0.6
-0.3
-0.2
-0.4
-0.6





20 CIDEA cell death inducing DFFA like effector a 490559 4.3 2.0
2.7
0.5
0.1
-0.3
-0.6
2.2
1.2
-0.6
-1.1
0.5
-0.2
0.5
0.3
2.8
0.6
0.5
0.1
1.5
0.3
0.1
-0.5
-0.3
-0.8
0.4
0.2
-0.5
-0.5
3.5
1.1
1.2
-0.1
-0.3
-1.2
-0.4
-0.4
1.5
0.1
0.0
-0.1




21 LOC479821 acyl-coenzyme A synthetase ACSM4, mitochondrial 479821 4.2 2.4
1.9
0.5
0.5
0.9




















22 CYYR1 cysteine and tyrosine rich 1 478395 4.1 1.5
3.1
0.4
-0.3
-0.4
0.8
0.1
-0.1
0.8
-1.4
-0.4
-0.9
-1.2
0.3
1.5
0.5
0.2
-2.0
-0.8
-2.7





23 GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 477056 4.0 2.0
2.3
-0.6
-0.0
0.5


-0.2
0.9
0.4





-0.1
-0.6
-1.2







24 FMO3 flavin containing dimethylaniline monoxygenase 3 403603 4.0 1.2
3.4
1.9
0.1
0.7
0.6
1.3
1.2
1.6
1.5
0.0
-0.2
2.0
0.3
2.8
2.1
1.5
-0.6
0.4
-0.1
0.7
0.6
0.5
-0.7
1.8
0.3
0.2
-0.6
-1.2
1.0
-0.3
1.2
0.3
0.9
0.7
1.8
1.2
2.3
0.2
2.6
1.7
1.2
0.1
-0.5
0.6
25 LOC100688697 cytochrome P450 2C23-like 100688697 4.0 2.1

0.4
-0.1
0.3
0.2
0.0
0.0
-0.1
-0.1
-0.2
-0.5
1.4
0.3
3.2
1.4
0.2
-0.1
0.1
0.0
0.6
0.6
0.7
0.1
0.9
0.4
0.3
-0.0
0.1
-0.1
1.1
1.0
0.6
0.2
0.9
-0.7
-0.3
-0.3

-0.4
-0.3


26 FGB fibrinogen beta chain 475472 4.0 1.9
2.3
-0.7
-0.8
-0.0
-1.7
0.5
0.1
0.6
-0.4
0.3
0.1
-0.7
0.6
-1.7
-2.3
0.8
-0.6
-0.2
-0.9





27 TTN titin 478820 4.0 2.1
2.0
0.9
-0.4
-0.3





0.7
-0.2
0.6
1.9
-0.1
0.2
-0.0
0.0
0.3
-0.5
0.3
0.1
0.6
-0.4
-0.0


28 TENM2 teneurin transmembrane protein 2 489135 3.9 1.3
3.2
0.6
0.0
0.5
-0.2
1.0
0.9
-0.3
-0.7
0.5
0.4
-0.5
-0.6
0.8
-0.1
0.4
0.1
0.6
-0.5
-0.2
-0.5
-0.0
-0.2
0.6
-0.2
0.8
-0.4
1.7
1.5
0.4
-0.6
0.8
-0.3
0.6
0.4
0.2
-0.0
0.9
0.1
-0.3
-0.2


29 RHBG Rh family B glycoprotein 403538 3.9 1.1
3.3
1.8
0.2
1.2
1.2
0.4
0.2
0.9
-0.5
0.8
-0.2
0.3
0.3
0.5
0.4
0.9
0.6
1.1
1.0
0.7
0.0
0.1
-0.1
2.4
-1.2
1.1
0.1
0.3
-0.1
0.3
-0.3
0.4
0.4
1.4
0.9
0.2
0.2
-0.1
1.0
-0.5
1.0
0.5


30 CCDC68 coiled-coil domain containing 68 483973 3.9 2.0
2.1
-1.1
-1.5
0.9
0.6
-0.8
1.7
0.1
-0.1


-0.7
-0.1
-0.3










31 PALMD palmdelphin 479933 3.9 1.7
2.4
-0.6
-0.5
-1.3
-0.2
-0.2
0.1
0.7
-1.6
-0.2
-1.5
-0.0
-0.4
0.1
-0.5
0.6
-0.2
0.3
-1.1





32 ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 491368 3.7 1.1
3.1
-0.3
-0.4
-0.3
-0.6
-1.3
0.1
-0.5
0.0
-0.7
-0.5
-1.9
-1.1
0.0
0.2
-0.5
0.4
-0.0
-0.3
0.6
-0.4





33 RERGL RERG like 486658 3.6 2.1
1.7
-0.6
-1.2
-1.1







-0.7
-0.9
1.8
0.2
-0.4
-0.9
-0.9
0.2
0.3
-1.1
-2.1


34 LEP leptin 403616 3.6 2.7
0.9
1.0
-0.8
1.8
-0.7
0.2
-1.4
2.1
0.4
3.8
0.4
0.6
-1.8
-0.8










35 A1CF APOBEC1 complementation factor 477581 3.6 1.7
2.1
0.4
-0.8
-0.9
-0.6
-0.6
-0.5
-0.1
-1.2
-0.2
0.4
-0.0
-0.1
-1.0
-0.2
0.4
0.5
0.5
-1.1





36 ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 476590 3.5 1.8
2.0
-0.1
-0.6
-1.1
-1.6
-0.5
-0.3
0.1
-0.7
-0.6
0.2
0.2
0.3
-0.5










37 ASB5 ankyrin repeat and SOCS box containing 5 482933 3.5 1.0
2.9
0.3
0.2
0.2
0.1
0.5
0.4
0.3
0.2
-0.3
-0.5
1.1
0.4
1.6
0.6
0.5
-0.1
1.4
-1.4
0.5
0.3
0.4
0.1
0.7
-0.5
-1.4
1.2
-0.4
0.4
-0.9
0.8
-0.1
0.1
-0.3

-0.4
0.7


38 LOC611458 pregnancy zone protein-like 611458 3.5 1.5
2.3
-0.3
-0.3
0.9
-0.4
1.6
0.3
-0.3
-1.4
-0.9
-1.0
0.4
0.4
0.5
0.4
-0.1
-0.6
0.9
0.1
0.4
0.2
0.9
0.2
0.7
1.6
0.4
-0.1
-0.6
0.7
-0.5
1.0
0.1







39 PTGER3 prostaglandin E receptor 3 403430 3.5 1.6
2.2
1.1
0.1
0.4


0.1
1.1
0.8
-0.2
0.3
-0.0
-0.4
-1.2
0.7
-0.8
0.1
-0.9
0.7





40 SERPINA4 serpin family A member 4 490840 3.5 1.4
2.5
0.5
0.1
-0.8
-1.5
-0.5



0.3
-0.3
-0.9
-0.9
0.1










41 NPY2R neuropeptide Y receptor Y2 482661 3.5 2.4
1.1
0.2
0.7
1.3


-0.4
-0.5
-0.5





-0.3
0.7
0.2
1.0
-0.5
-0.0
1.3
0.2
1.4
1.3


42 NNAT neuronatin 609195 3.4 1.3
2.5
-0.9
-0.4
2.2
0.1
1.1
0.0
0.9
0.1
0.7
-0.5
0.0
0.0
-0.0










43 APOH apolipoprotein H 403945 3.4 1.4
2.3
-0.6
-1.1
-0.5
-1.0
-0.0
-0.2
0.7
-0.2
-0.5
0.3
-1.5
-0.8
-0.6
-0.9
0.2
-0.1
-1.6
1.3
1.2




44 KNG1 kininogen 1 478666 3.4 1.7
1.9
-0.3
-0.1
-1.2
-0.6
-1.3
0.1
0.1
0.6
0.4
-0.9
-1.0
0.0
0.0
1.0
0.2
-1.6
-0.3
-0.9
-1.0
-0.3
-0.1
-0.9
-1.5
1.9
-0.8

1.7
1.1
0.5
0.4


45 GYG2 glycogenin 2 491717 3.4 1.2
2.6
0.6
-1.0
0.7
-0.3
1.4
-0.9
1.7
0.1
-0.0
-0.5
-1.6
1.6
0.6
0.7
-1.9
0.7
-0.9
1.4
0.9
1.2
0.2
0.2
0.1
0.2
-1.1
1.1
-0.7
0.5
0.3
0.0
-0.5
2.8
1.4
1.3
0.7
0.0
3.3
2.4
2.6
1.0
46 LOC489397 nicotinamide N-methyltransferase 489397 3.4 1.8
1.8
0.3
0.1
0.5
0.5
0.3
-0.5
-0.3
-0.4
0.8
-0.9
0.9
-1.4
2.9
0.8
-0.8
-0.9
0.7
-0.5
-0.2
-1.1
-0.7
-0.9
0.4
-0.6
-0.3
-0.7
-0.3
-0.3
0.1
-0.9
-0.4

0.5
0.4
1.5
1.0


47 ABCA6 ATP binding cassette subfamily A member 6 480456 3.4 1.0
2.8
0.0
-0.6
0.3
-0.2
-0.5
-1.3
0.6
0.3
-0.9
-1.3
1.7
1.5
1.5
1.3
0.5
-1.2
0.0
-1.1
0.4
-0.1
-0.4
-0.5
-0.4
-0.7
0.8
-0.0
3.2
0.8
1.7
1.2
0.4
-1.7


1.4
1.0
0.2
-0.5


48 FABP4 fatty acid binding protein 4 608476 3.4 1.9
1.6
0.5
-0.3
0.6
0.2
0.8
0.5
2.3
0.6
0.9
0.6
0.7
0.2
2.8
1.1
0.4
0.1
1.7
0.5
0.7
0.6
1.0
0.6
1.0
0.6
0.6
0.0
2.3
2.3
1.1
0.9
0.0
-0.8
0.3
-0.2
0.9
0.4

0.2
-0.1
0.6
0.1


49 PLAAT3 phospholipase A and acyltransferase 3 476045 3.4 1.1
2.7
-0.2
-0.8
1.4
-0.5
-0.6
0.8
-0.6
-1.3
0.9
-1.2
0.2
-1.8
-1.2
-3.0
-0.1
-1.5
0.0
-0.8



0.1
-0.2
0.2
-0.1





50 FETUB fetuin B 478665 3.3 2.0
1.4
-1.0
0.2
-0.9
-1.9
-1.2
0.5
0.7
-1.3
-0.3
0.4
-0.5
-0.5
-0.2
0.4
-0.5
-0.2
-0.4
0.5





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