Orthologous genes in OrthoFinder**

Species Gene Description
 cfa-u.3   LETM1   leucine zipper and EF-hand containing transmembrane protein 1 
 cfa-r.3   LETM1   leucine zipper and EF-hand containing transmembrane protein 1 
 cfa-m.4   LETM1   leucine zipper and EF-hand containing transmembrane protein 1 
 hsa-u.4   LETM1   leucine zipper and EF-hand containing transmembrane protein 1 
 mmu-u.4   Letm1   leucine zipper-EF-hand containing transmembrane protein 1 
 rno-u.3   Letm1   leucine zipper and EF-hand containing transmembrane protein 1 
 mcc-u.3   LETM1   leucine zipper and EF-hand containing transmembrane protein 1 
 gga-u.3   LETM1   leucine zipper and EF-hand containing transmembrane protein 1 
 dre-u.3   letm1   leucine zipper-EF-hand containing transmembrane protein 1 
 dme-u.3   Letm1   Leucine zipper and EF-hand containing transmembrane protein 1 
 cel-u.3   letm-1   LETM1 (Leucine zipper, EF-hand, TransMembrane mitochondrial protein) homolog 
 sce-u.3   YLH47   Ylh47p 
 sce-u.3   MDM38   ribosome-binding protein MDM38 

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Top 50 coexpressed genes to LETM1 (cfa-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 cfa5014   Amyotrophic lateral sclerosis  7 300 4.31
 cfa5022   Pathways of neurodegeneration - multiple diseases  7 398 3.55
 cfa5012   Parkinson disease  6 227 4.05
 cfa5010   Alzheimer disease  6 326 3.20
 cfa5016   Huntington disease  5 254 2.86

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cfa:LETM1 (leucine zipper and EF-hand containing transmembrane protein 1) External Links;


Show/Hide Columns:        
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

cfa-u.3
for
LETM1
cfa-r.3
for
LETM1
cfa-m.4
for
LETM1
hsa-u.4
for
LETM1
mmu-u.4
for
Letm1
rno-u.3
for
Letm1
mcc-u.3
for
LETM1
gga-u.3
for
LETM1
dre-u.3
for
letm1
dme-u.3
for
Letm1
cel-u.3
for
letm-1
sce-u.3
for
YLH47
sce-u.3
for
MDM38
1 WDR37 WD repeat domain 37 607652 6.4 3.0
 3.8
 0.9
 0.2
 1.9
 0.7
 -0.1
 -0.5
 1.7
 -0.5

2 GRPEL1 GrpE like 1, mitochondrial 488784 6.4 3.2
 3.5
 6.2
0.5
 2.2
0.1
 3.4
-0.6
 0.1
 1.7
0.9
 1.5
0.8
 1.3
 3.1
 -0.4
 0.5
3 NOP14 NOP14 nucleolar protein 479076 6.2 3.5
 3.0
 8.3
 1.3
 0.9
 4.6
 5.7
 0.5
 0.2
 1.1
 -0.1
 1.6
4 LRRC59 leucine rich repeat containing 59 491080 6.1 2.8
 3.7
 3.5
 3.0
 3.5
 6.1
 0.7
 0.4
 -0.6


5 EIF4G1 eukaryotic translation initiation factor 4 gamma 1 100688785 5.9 3.1
6.4
 4.6
 3.6
1.3
 5.4
-0.3
 2.6
0.8
 2.2
1.7
 2.8
1.1
 2.9
 1.4
 1.3
6 POLG DNA polymerase gamma, catalytic subunit 100856383 5.7 3.0
5.2
 0.6
 1.4
 3.7
 -0.7
 0.6
 0.6
 -0.4
 -0.4
 -0.1
7 OGDH oxoglutarate dehydrogenase 475499 5.7 3.0
3.2
0.7
 7.8
-0.6
 4.9
0.3
 6.3
-0.1
 0.7
0.0
 2.6
2.4
 3.9
 1.9
 -0.2
 1.2
8 UNC45A unc-45 myosin chaperone A 488743 5.6 3.2
 2.6
 3.2
-0.9
 3.1
-0.8
 1.5
-0.3
 4.2
-0.8
 0.5
-0.5
 -0.4
-0.9
 2.4
 2.3
 -1.4
 -0.5
9 IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha 479066 5.2 2.5
 3.1
 3.8
 5.5
 2.7
 3.3
 1.7
 0.5
 1.3
 -0.2
 0.6
 -0.3
10 TOMM40 translocase of outer mitochondrial membrane 40 611055 5.1 2.8
 2.6
 5.1
3.5
 4.8
2.3
 5.5
2.3
 5.4
0.9
 1.1
0.5
 0.9
-0.2
 -0.9
-0.9
 1.5
 1.3
 1.7
11 DDX54 DEAD-box helicase 54 486279 4.9 2.6
 2.6
 4.4
 3.1
 2.1
 2.9
 2.7
 0.7
 0.6
 0.9
 0.8
 2.6
12 KLF13 Kruppel like factor 13 119871187 4.9 2.6
0.8
 0.4
 0.8
 1.1
 2.0
 2.1
1.0



13 INTS1 integrator complex subunit 1 100685475 4.9 2.6
3.8
 3.4
 4.9
 5.1
 1.1
 -0.6
 2.6
 1.5

14 TRMT44 tRNA methyltransferase 44 homolog 488791 4.7 2.7
 2.2
 4.8
 0.6
 0.3
 1.2
 1.1
 -0.9
 -1.3
 2.8
 0.6
 0.1
15 ADRM1 ADRM1 26S proteasome ubiquitin receptor 100855986 4.6 2.5
2.1
 2.9
 1.5
 2.4
 0.2
 -0.4
 2.6
-0.0
 0.8

16 TBRG4 transforming growth factor beta regulator 4 482691 4.6 2.5
 2.4
 5.0
 4.2
 2.4
 4.0
 1.2
 0.6
 0.9


17 LRRC47 leucine rich repeat containing 47 489622 4.6 2.3
 2.6
 4.9
 2.4
 2.1
 3.4
 -1.0
 -0.8
0.4

18 CLUH clustered mitochondria homolog 491203 4.6 2.1
 2.9
 9.7
 4.8
 3.6
 6.2
 2.5
 2.4
-0.4
 2.2
 3.8
 2.9
 3.3
19 EIF6 eukaryotic translation initiation factor 6 477210 4.6 2.0
 2.9
 1.8
 1.3
 1.4
 1.2
 0.4
 -0.8
 0.2
 -0.2
 0.8
 0.3
20 ZC3H18 zinc finger CCCH-type containing 18 489665 4.5 2.7
 2.0
3.5
 1.1
 3.5
 0.2
 0.9
 0.6


21 MRPL16 mitochondrial ribosomal protein L16 100855464 4.5 2.4
1.5
 5.3
 3.2
 0.3
 1.9
 0.9
 -1.2
 1.1
 1.0
 1.7
22 KIF5B kinesin family member 5B 100855651 4.5 2.4
1.6
0.7
 1.4
0.8
 2.1
0.4
 0.7
-0.5
 3.6
1.4
 4.2
4.0
 0.5
 3.1

23 GAK cyclin G associated kinase 479133 4.5 2.3
 2.5
 7.7
0.7
 2.7
-0.1
 3.1
0.9
 3.2
0.0
 1.2
0.0
 0.8
-0.9
 0.9
 1.8
0.7
 0.1
 0.4
24 NIPA2 NIPA magnesium transporter 2 479002 4.5 2.7
 1.9
 2.4
 0.8
 1.0
 0.9
 -0.2
-1.5
 1.9
-0.5
 0.5
 -1.2

25 WDR1 WD repeat domain 1 611070 4.5 2.2
 2.5
 4.5
 1.4
 1.0
 3.1
 -0.6
 -1.7
 -1.8
 0.2
-0.4
 -1.1
 -0.3
26 GSPT1 G1 to S phase transition 1 479846 4.4 1.9
 3.0
 2.8
-0.1
 3.6
-0.7
 3.3
0.2
 3.5
 3.5
 0.9
-0.8
 2.0
 3.4
 1.1
 0.8
27 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 479182 4.4 2.6
 1.9
 1.1
 0.3
 1.8
 2.1
 -0.4
 1.4
-1.2
 2.5
 6.0
 -0.4
-1.0
 1.0
-0.1
28 SLC39A1 solute carrier family 39 member 1 100855713 4.4 2.4
2.7
0.4
 2.3
-0.5
 1.0
0.2
 3.0
2.6
 0.5
 0.1
-1.5
 -0.3
-0.6
 0.9

29 HSPA4 heat shock protein family A (Hsp70) member 4 474680 4.4 2.4
 2.1
 3.7
1.1
 4.0
3.0
 3.5
2.7
 4.3
2.1
 3.2
2.3
 0.9
0.4
 1.0
 1.8
 2.8
0.2
 1.0
-0.9
30 IPPK inositol-pentakisphosphate 2-kinase 484215 4.3 2.2
 2.3
 2.1
 0.8
 1.7
 4.5
 1.0
 0.5
 -0.2
 1.1

31 NSD2 nuclear receptor binding SET domain protein 2 479077 4.3 2.4
 2.2
 0.4
 0.3
0.3
 1.7
1.2
 2.3
0.6
 4.2
0.9
 0.5
-0.4
 1.4


32 UQCRC1 ubiquinol-cytochrome c reductase core protein 1 608455 4.3 2.4
 2.1
 3.0
-0.7
 6.1
3.2
 3.5
2.1
 2.1
0.1
 1.4
0.9
 1.5
0.2
 3.3
 3.3
 1.4
 1.7
33 REEP4 receptor accessory protein 4 486129 4.2 1.6
 3.1
 0.6
0.3
 1.1
0.5
 1.0
0.5
 1.5
0.2
 1.4
0.7
 1.1
0.7
 -0.0
 -1.0

34 MRPL12 mitochondrial ribosomal protein L12 608030 4.2 2.6
 1.7
 4.0
 3.0
 2.1
 2.9
 3.0
 0.8
 -0.9
 -0.2
 0.8
 1.6
35 DHX15 DEAH-box helicase 15 488856 4.2 2.7
 1.7
 3.4
3.3
 3.2
2.4
 2.6
2.1
 4.5
3.0
 2.6
1.9
 3.8
2.1
 1.3
0.9
 5.0
4.0
 1.8
0.7
 2.3
2.2
36 MAP2K3 mitogen-activated protein kinase kinase 3 489547 4.2 2.3
 2.1
 2.2
-0.6
 1.1
-0.6
 0.5
-0.8
 1.6
-0.3
 1.0
-0.0
 1.2
 -0.0
 -0.7

37 SLC25A38 solute carrier family 25 member 38 477028 4.2 2.4
 1.9
 1.4
 2.1
 0.1
 1.9
 -0.2
 0.9
-1.3

0.1
 -1.1
38 PMPCA peptidase, mitochondrial processing subunit alpha 480677 4.2 2.0
 2.5
 5.3
 3.5
 3.3
 5.7
 2.5
 0.4
 1.8
 2.4
 2.6
 3.6
39 DUS1L dihydrouridine synthase 1 like 475927 4.2 2.3
 2.1
 4.1
 3.0
 1.7
 1.8
 1.2
 1.0
 -0.0
 2.3
 3.5
 -0.1
40 ATAD3A ATPase family AAA domain containing 3A 479568 4.2 1.7
 2.9
 5.6
4.3
 3.5
 3.4
 2.4
1.0
 0.9
 0.6
 1.0
 5.6

41 POLR1A RNA polymerase I subunit A 475766 4.1 1.3
 3.4
 6.8
 0.9
 1.2
 7.2
 2.2
 2.8
 1.0
 0.2
 -0.9
 -0.0
42 PSMD3 proteasome 26S subunit, non-ATPase 3 491018 4.1 2.8
 1.4
 3.6
 4.4
 3.1
 3.1
 1.1
 -1.8
 1.5
 0.9
 0.0
 -0.9
43 MYBBP1A MYB binding protein 1a 489442 4.1 2.2
 2.1
 5.2
 0.7
 0.9
 3.8
 3.3
 2.7
 0.2
-0.4
 -0.7
44 TBL3 transducin beta like 3 490064 4.1 2.0
 2.4
 4.4
 3.1
 1.0
 3.7
 0.1
 -1.0
 1.0
 2.2
 0.5
 0.3
45 NRDC nardilysin convertase 475354 4.1 2.2
 2.1
 -0.1
 1.7
 1.4
 1.4
 2.0
 1.3
-0.4
 0.8
-0.3


46 USP5 ubiquitin specific peptidase 5 486718 4.1 2.5
 1.7
 3.7
0.6
 2.7
0.5
 1.3
 5.2
-0.3
 0.6
0.5
 -0.1
-0.2
 0.0
-0.8
 1.6
47 MRPL46 mitochondrial ribosomal protein L46 479035 4.1 1.8
 2.6
 1.4
 3.6
 3.8
 1.9
 3.1
 1.4
 0.0
 -0.5
 2.1
 2.1
48 TUBB4B tubulin beta 4B class IVb 102153202 4.1 2.2
1.6
0.7
 1.9
0.4
 2.8
2.0
 3.3
2.2
 1.1
0.8
 0.5
-0.3
 0.6
0.1
 1.8
1.3
 0.6
 -0.3
49 HECTD3 HECT domain E3 ubiquitin protein ligase 3 482518 4.1 1.5
 3.0
 3.6
 4.2
 2.6
 2.3
 1.1
 1.2



50 VARS1 valyl-tRNA synthetase 1 481716 4.0 2.1
 2.2









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