Orthologous genes in OrthoFinder**

Species Gene Description
 cfa-u.3   EGR1   early growth response 1 
 cfa-r.3   EGR1   early growth response 1 
 cfa-m.4   EGR1   early growth response 1 
 cfa-u.3   EGR3   early growth response 3 
 cfa-u.3   EGR2   early growth response 2 
 hsa-u.4   EGR2   early growth response 2 
 hsa-u.4   EGR3   early growth response 3 
 hsa-u.4   EGR1   early growth response 1 
 mmu-u.4   Egr3   early growth response 3 
 mmu-u.4   Egr2   early growth response 2 
 mmu-u.4   Egr1   early growth response 1 
 rno-u.3   Egr3   early growth response 3 
 rno-u.3   Egr2   early growth response 2 
 rno-u.3   Egr1   early growth response 1 
 mcc-u.3   EGR3   early growth response 3 
 mcc-u.3   EGR1   early growth response 1 
 mcc-u.3   EGR2   early growth response 2 
 gga-u.3   101748577   uncharacterized LOC101748577 
 gga-u.3   EGR3   early growth response 3 
 gga-u.3   EGR1   early growth response 1 
 dre-u.3   797711   zinc finger protein ZFP69-like 
 dre-u.3   egr3   early growth response 3 
 dre-u.3   egr2b   early growth response 2b 
 dme-u.3   sr   stripe 
 cel-u.3   egrh-3   EGR (Early Growth factor Response factor) Homolog 
 cel-u.3   egrh-2   EGR (Early Growth factor Response factor) Homolog 
 cel-u.3   egrh-1   EGR (Early Growth factor Response factor) Homolog 

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Top 50 coexpressed genes to EGR1 (cfa-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 cfa4010   MAPK signaling pathway  9 258 6.90
 cfa4657   IL-17 signaling pathway  6 74 6.86
 cfa4668   TNF signaling pathway  6 102 6.03
 cfa4380   Osteoclast differentiation  6 105 5.96
 cfa4625   C-type lectin receptor signaling pathway  5 93 4.90

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cfa:EGR1 (early growth response 1) External Links;


Show/Hide Columns:        
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

cfa-u.3
for
EGR1
cfa-r.3
for
EGR1
cfa-m.4
for
EGR1
cfa-u.3
for
EGR3
cfa-u.3
for
EGR2
hsa-u.4
for
EGR2
hsa-u.4
for
EGR3
hsa-u.4
for
EGR1
mmu-u.4
for
Egr3
mmu-u.4
for
Egr2
mmu-u.4
for
Egr1
rno-u.3
for
Egr3
rno-u.3
for
Egr2
rno-u.3
for
Egr1
mcc-u.3
for
EGR3
mcc-u.3
for
EGR1
mcc-u.3
for
EGR2
gga-u.3
for
101748577
gga-u.3
for
EGR3
gga-u.3
for
EGR1
dre-u.3
for
797711
dre-u.3
for
egr3
dre-u.3
for
egr2b
dme-u.3
for
sr
cel-u.3
for
egrh-3
cel-u.3
for
egrh-2
cel-u.3
for
egrh-1
1 FOS Fos proto-oncogene, AP-1 transcription factor subunit 490792 20.4 10.9
 10.1
 4.4
 10.1
 11.7
 10.9
 24.5
 6.5
 10.8
 22.1
 3.9
 12.2
 19.8
 1.9
 12.5
 9.3
 5.2
 4.8
 15.9
 4.4
 7.0
 3.4



2 IER2 immediate early response 2 484917 15.8 8.2
 8.1
 3.7
 7.0
 8.6
 8.7
 16.5
 6.1
 8.0
 17.6
 2.9
 7.7
 13.5
 5.4
 12.0
 9.6


3.9
3.3
 7.5
6.0
 3.2
2.6



3 JUNB JunB proto-oncogene, AP-1 transcription factor subunit 100856456 13.6 7.2
6.2
3.2
 9.9
4.4
 9.3
6.3
 9.2
4.7
 14.7
10.9
 6.8
3.0
 9.2
5.2
 16.9
9.7
 4.3
1.9
 10.4
4.1
 15.4
6.6
 2.9
2.0
 9.4
7.4
 8.1
4.8
 6.0
3.5
 4.3
2.3
 9.1
6.1
 2.7
1.9
 7.8
6.6
 1.7
1.6
 1.4
 -1.0
 0.7
 3.5
4 ZFP36 ZFP36 ring finger protein 484510 13.4 7.2
 6.7
 4.0
 7.9
 6.4
 7.8
 13.3
 4.1
 5.6
 12.2
 1.8
 5.5
 9.7
 2.4
 8.4
 2.8
 5.7
 4.4
 6.1
 0.2
-0.2
 0.0
-0.9
 1.8
-0.8
-0.7
 0.1
 2.7
5 EGR2 early growth response 2 479219 13.0 9.0
 3.8
 10.4
6.5
 13.0
10.4
 21.7
20.5
 21.7
20.5
 20.5
20.5
 21.8
15.2
 21.8
19.2
 19.2
15.2
 7.6
6.4
 16.9
7.6
 16.9
6.4
 10.6
8.3
 16.3
8.3
 16.3
10.6
 9.5
7.3
 9.5
7.0
 7.3
7.0
 7.3
3.7
 10.0
9.7
 5.1
4.6
1.5
1.3
 1.5
0.3
 1.3
0.3
6 DUSP1 dual specificity phosphatase 1 489117 11.6 6.0
 6.2
 2.8
 6.5
 4.3
 4.4
 10.9
 2.1
 5.3
 10.7
 1.6
 5.6
 8.3
 1.5
 8.0
 6.2
 1.8
 1.8
 9.6
 1.1
 5.4
 1.5



7 BTG2 BTG anti-proliferation factor 2 488559 11.5 6.2
 5.7
 4.0
3.4
 7.1
2.6
 6.7
1.0
 6.7
0.8
 6.7
1.4
 4.8
2.8
 6.9
2.7
 10.5
3.3
 2.2
1.4
 7.1
1.1
 9.2
1.9
 2.3
-0.3
 4.6
-0.3
 5.6
0.8
 2.6
-0.1
 3.0
-0.0
 7.6
2.8
 3.2
1.6
 7.1
6.3
 4.1
1.3
-0.2
 1.4
 -0.5
8 NR4A1 nuclear receptor subfamily 4 group A member 1 403897 11.3 6.0
 5.8
 4.0
3.3
 7.2
4.6
 8.2
6.8
 10.1
8.6
 8.3
7.3
 11.1
8.1
 11.4
7.4
 14.5
4.5
 4.7
3.4
 12.0
7.7
 12.9
6.1
 7.3
6.7
 10.7
5.4
 10.6
6.5
 5.6
4.2
 7.3
7.1
 9.3
7.1
 3.4
1.0
 9.5
8.6
 3.0
2.7
 9.7
 0.8
 -0.5
 7.1
9 FOSB FosB proto-oncogene, AP-1 transcription factor subunit 484445 10.2 6.4
 3.8
 4.2
 7.0
 12.7
 13.5
 20.9
 9.5
 10.1
 16.0
 10.6
 11.1
 13.7
 6.5
 13.2
 9.2
 7.6
 8.9
 9.1
 2.8
 8.5
 2.2



10 ATF3 activating transcription factor 3 612911 9.7 4.4
 5.9
 3.1
 6.2
 7.8
 5.9
 7.8
 4.3
 7.2
 6.8
 1.7
 7.0
 6.5
 1.0
 3.1
 4.8
 2.4
 1.7
 6.4
 1.1
 5.5
 0.1



11 LOC111095540 uncharacterized LOC111095540 111095540 7.8 4.1
























12 JUN Jun proto-oncogene, AP-1 transcription factor subunit 609429 7.7 4.8
 3.0
 6.2
3.2
 9.9
4.4
 9.3
6.3
 9.2
4.7
 14.7
10.9
 6.8
3.0
 9.2
5.2
 16.9
9.7
 4.3
1.9
 10.4
4.1
 15.4
6.6
 2.9
2.0
 9.4
7.4
 8.1
4.8
 6.0
3.5
 4.3
2.3
 9.1
6.1
 2.7
1.9
 7.8
6.6
 1.7
1.6
 1.4
 -1.0
 0.7
 3.5
13 PPP1R15A protein phosphatase 1 regulatory subunit 15A 476419 7.7 3.8
 4.2
 2.3
 4.2
 5.1
 4.9
 8.4
 2.0
 3.8
 7.3
 2.1
 4.7
 7.0
 1.1
 3.4
 2.4
 3.9
 3.6
 7.9
 0.3
-0.3
 3.6
0.6
 0.2
-0.4
 -0.3


14 KLF6 Kruppel like factor 6 487151 7.3 3.6
 4.0
 1.8
-1.0
 3.6
0.2
 3.4
 2.9
 6.7
 2.5
0.6
 4.0
1.5
 5.3
2.0
 1.2
0.1
 3.4
0.6
 4.7
1.1
 0.4
0.2
 2.5
0.2
 3.3
0.7
 2.9
-0.2
 3.0
-0.1
 6.2
0.1
 1.7
1.6
 3.1
1.2
 0.7
0.4
 1.6
 0.7
 -0.1
 1.7
15 BHLHE40 basic helix-loop-helix family member e40 484680 6.8 3.6
 3.5
 1.9
 4.9
 4.9
 4.5
 4.4
 3.1
 4.2
 3.8
 0.8
 4.4
 4.8
 1.8
 3.0
 6.1
 4.2
 4.4
 4.3
 2.1
 3.0
 0.5



16 EGR3 early growth response 3 486121 6.5 5.9
 0.2
 10.4
6.5
 13.0
10.4
 21.7
20.5
 21.7
20.5
 20.5
20.5
 21.8
15.2
 21.8
19.2
 19.2
15.2
 7.6
6.4
 16.9
7.6
 16.9
6.4
 10.6
8.3
 16.3
8.3
 16.3
10.6
 9.5
7.3
 9.5
7.0
 7.3
7.0
 7.3
3.7
 10.0
9.7
 5.1
4.6
1.5
1.3
 1.5
0.3
 1.3
0.3
17 PLK3 polo like kinase 3 475380 6.2 3.3
 3.3
 1.8
0.9
 3.9
1.6
 5.3
1.3
 5.2
2.5
 5.0
2.2
 3.8
3.7
 4.8
4.1
 5.0
4.8
 3.3
1.5
 4.6
4.4
 4.9
4.6
 3.9
2.3
 2.5
1.9
 3.8
2.6
 2.9
0.8
 3.9
2.1
 4.6
3.9
 3.5
2.9
 5.7
4.6
 2.3
0.8
 -0.1
 1.6
0.5
 2.8
1.6
 0.0
-0.5
18 DUSP6 dual specificity phosphatase 6 482594 6.0 3.4
 2.9
 3.4
1.6
 4.2
0.6
 5.8
0.2
 4.4
1.0
 7.7
0.8
 5.9
1.2
 6.7
0.1
 8.5
1.0
 1.4
0.8
 5.9
0.7
 8.4
1.8
 2.2
1.0
 4.7
1.4
 4.3
0.1
 1.5
0.3
 2.2
0.7
 3.4
1.4
 1.8
1.5
 2.9
2.2
 2.5
1.2
 4.5
 2.0
 1.9
 2.3
19 DUSP5 dual specificity phosphatase 5 486884 6.0 2.9
 3.4
 3.4
 4.9
 4.6
 5.5
 5.3
 5.7
 6.3
 7.1
 2.5
 4.9
 6.0
 1.4
 1.5
 1.8
 4.7
 5.1
 7.4
 2.7
 8.2
 4.2



20 ZFP36L1 ZFP36 ring finger protein like 1 490748 6.0 4.3
 1.6
 2.5
2.3
 4.2
1.5
 4.5
1.4
 3.8
1.8
 5.7
3.6
 4.8
2.7
 4.5
1.8
 5.9
4.1
 1.8
1.5
 2.2
2.2
 4.7
2.6
 3.4
0.5
 2.8
1.7
 2.7
1.8
 2.4
0.6
 4.5
1.0
 5.3
3.1
 2.1
0.6
 5.9
2.2
 1.2
1.2
 0.0
 1.0
0.8
 0.4
0.1
 1.5
1.4
21 TRIB1 tribbles pseudokinase 1 482039 6.0 3.6
 2.5
 3.6
0.5
 4.1
1.4
 7.3
1.7
 6.4
0.7
 8.2
1.1
 5.0
2.2
 6.3
1.5
 7.2
1.3
 3.7
0.1
 6.1
0.9
 5.7
0.2
 2.3
-0.2
 5.3
0.6
 5.7
1.8
 3.3
1.1
 3.2
1.6
 4.8
2.4
 1.0
0.9
 3.7
2.9
 -0.0
-0.4
 -0.1


22 NFKBIZ NFKB inhibitor zeta 478549 5.9 3.6
 2.5
 3.0
2.7
 4.1
3.8
 4.6
3.6
 5.4
4.2
 7.1
2.5
 4.7
4.0
 4.8
4.4
 7.6
4.4
 3.5
1.7
 5.1
2.6
 5.7
1.9
 5.6
1.0
 2.6
2.1
 2.9
2.4
 1.6
1.4
 2.1
0.8
 3.0
1.7
 -0.7
-1.6
 0.8
-1.6
 0.6
-1.4
-1.6
 -1.1
 1.4
23 JUND JunD proto-oncogene, AP-1 transcription factor subunit 609409 5.9 3.1
6.2
3.2
 9.9
4.4
 9.3
6.3
 9.2
4.7
 14.7
10.9
 6.8
3.0
 9.2
5.2
 16.9
9.7
 4.3
1.9
 10.4
4.1
 15.4
6.6
 2.9
2.0
 9.4
7.4
 8.1
4.8
 6.0
3.5
 4.3
2.3
 9.1
6.1
 2.7
1.9
 7.8
6.6
 1.7
1.6
 1.4
 -1.0
 0.7
 3.5
24 NR4A2 nuclear receptor subfamily 4 group A member 2 478754 5.6 2.8
 3.1
 4.0
3.3
 7.2
4.6
 8.2
6.8
 10.1
8.6
 8.3
7.3
 11.1
8.1
 11.4
7.4
 14.5
4.5
 4.7
3.4
 12.0
7.7
 12.9
6.1
 7.3
6.7
 10.7
5.4
 10.6
6.5
 5.6
4.2
 7.3
7.1
 9.3
7.1
 3.4
1.0
 9.5
8.6
 3.0
2.7
 9.7
 0.8
 -0.5
 7.1
25 CCN1 cellular communication network factor 1 479967 5.3 2.4
 3.3
 1.6
0.7
 1.8
1.4
 5.0
3.7
 4.1
2.4
 8.3
4.2
 4.0
1.8
 6.1
2.5
 8.5
1.8
 2.2
0.7
 7.0
2.8
 8.4
2.5
 3.3
2.5
 4.2
2.9
 4.8
4.0
 2.4
1.6
 3.2
1.6
 9.3
5.1
 1.2
0.5
 4.1
2.9
 2.5
1.7
 0.4


26 LOC119869317 uncharacterized LOC119869317 119869317 5.3 2.8
























27 HES1 hes family bHLH transcription factor 1 119865321 5.3 2.8
3.5
0.2
 2.5
0.6
 4.3
0.1
 4.2
1.2
 5.7
0.2
 2.4
 1.6
 3.4
 1.0
 3.2
 3.8
 1.9
1.5
 2.1
-0.7
 1.7
-0.5
 2.1
0.1
 2.0
1.3
 0.9
-0.0
 -0.2
-0.4
 2.0
0.0
 1.7
0.5
 1.4
0.4
 0.8
 0.1
 0.4
28 KLF2 Kruppel like factor 2 111091360 5.2 2.8
4.2
 5.1
 2.7
 3.4
 4.8
 3.6
 2.7
 4.5
 2.0
 3.6
 4.9
 2.3
 3.3
 3.1
 1.9
 3.8
 4.1
 1.2
-0.2
 3.8
2.1
 1.5
-0.1



29 LOC119873373 uncharacterized LOC119873373 119873373 5.2 2.8
























30 ERRFI1 ERBB receptor feedback inhibitor 1 489636 5.1 2.2
 3.3
 3.0
 3.4
 1.7
 2.2
 3.4
 2.2
 3.3
 3.7
 0.5
 3.2
 3.2
 1.4
 2.2
 1.0
 2.7
 3.0
 3.6
 1.5
 3.3
 -0.1



31 PTP4A1 protein tyrosine phosphatase 4A1 481863 5.1 2.3
 3.1
 1.6
0.0
 2.6
-0.8
 1.8
-0.0
 2.0
0.4
 2.6
0.1
 0.8
0.7
 0.6
0.3
 1.6
0.7
 0.6
0.3
 0.2
-0.2
 1.2
0.6
 0.9
0.9
 2.7
0.8
 2.6
0.8
 0.9
-0.7
 0.8
-0.6
 0.9
-0.2
 0.5
0.5
 1.0
0.1
 1.0
0.2
 0.4
 2.3
32 KLF4 Kruppel like factor 4 481657 5.0 3.0
 2.2
 1.6
 4.0
 4.3
 4.8
 6.4
 2.9
 3.4
 4.4
 2.6
 6.6
 5.7
 1.7
 4.6
 3.7
 2.5
 3.4
 3.0
 0.3
 4.3
 0.8



33 SGK1 serum/glucocorticoid regulated kinase 1 403647 4.8 2.6
 2.4
 2.6
-0.4
 3.0
0.3
 5.3
-0.1
 3.6
-0.4
 4.1
0.1
 1.8
0.3
 2.3
-0.2
 2.3
-0.1
 0.5
0.1
 3.7
0.2
 2.5
0.4
 0.8
-0.3
 2.3
0.2
 1.5
0.4
 1.2
-0.6
 0.6
-0.7
 3.5
-0.3
 1.8
1.0
 3.6
2.6
 1.4
1.1
0.0
 -0.9
 -0.2
34 LOC119881562 uncharacterized LOC119881562 119881562 4.6 2.4
























35 SOCS3 suppressor of cytokine signaling 3 442949 4.4 3.0
 1.5
 2.5
 3.7
 3.5
 4.2
 5.4
 1.7
 3.2
 4.6
 1.6
 3.6
 3.6
 0.8
 3.8
 3.4
 3.7
 2.5
 6.4
 2.1
-0.5
 3.5
-1.0
 1.8
-0.9



36 SERTAD1 SERTA domain containing 1 484500 4.4 2.0
 2.8
 1.4
 2.3
 7.1
 6.6
 7.1
 4.5
 5.0
 5.8
 1.6
 4.4
 3.8
 1.7
 3.8
 3.6









37 IER3 immediate early response 3 481708 4.3 1.9
 2.8
 1.2
 4.1
 5.5
 5.7
 6.8
 2.2
 3.3
 5.8
 0.1
 3.2
 5.0
 1.9
 3.4
 2.9


0.2
 4.3
 0.4



38 OTUD1 OTU deubiquitinase 1 111094497 4.2 2.2
1.7
 2.4
 2.5
 1.9
 2.5
 2.4
 2.3
 3.1
 2.4
 4.7
 4.7
 2.9
 3.6
 2.8
 1.2
 0.5
 3.4
 1.3
 2.5
 0.8



39 TNFAIP3 TNF alpha induced protein 3 484006 4.1 3.2
 0.9
 1.8
 3.9
 3.2
 2.8
 3.2
 3.2
 4.5
 4.6
 2.4
 2.8
 3.4
 1.2
 0.9
 2.1
 1.0
 1.0
 2.5
 -0.8
 2.9
 -1.1



40 DUSP2 dual specificity phosphatase 2 611653 4.1 2.2
4.5
 4.4
 6.8
 7.3
 6.4
 4.4
 3.0
 3.5
 1.6
 3.5
 2.2
 7.0
 6.5
 5.3


5.0
 11.1
 4.5



41 MCL1 MCL1 apoptosis regulator, BCL2 family member 403537 4.0 2.0
 2.3
 0.4
 1.7
 4.2
 4.4
 7.5
 1.6
 2.1
 1.9
 1.1
 2.3
 2.3
 0.0
 2.4
 1.0
 1.9
 1.7
 4.0
 1.5
0.7
 2.3
1.3
 0.8
0.6



42 MYC MYC proto-oncogene, bHLH transcription factor 403924 4.0 1.6
 2.8
 1.5
 2.2
 2.8
 2.8
 3.6
 3.2
0.3
 3.4
0.0
 3.0
-0.5
 0.8
-0.6
 2.1
-1.3
 2.9
-0.1
 0.2
 1.5
 3.1
 1.3
 2.5
 3.4
 1.8
1.7
 2.5
2.0
 3.4
2.5
 1.8


43 IRF2BPL interferon regulatory factor 2 binding protein like 100685860 4.0 2.1
3.1
 2.7
 2.7
 2.4
 3.0
 2.0
 2.1
 2.8
 2.7
 2.5
 3.4
 0.9
 0.7
 0.9
 1.9
 2.1
 1.9
 2.1
 2.0
 0.9



44 ID2 inhibitor of DNA binding 2 100686903 3.9 2.1
1.2
0.3
 2.7
1.4
 2.7
1.6
 2.4
2.1
 3.5
3.0
 2.5
1.5
 1.6
1.0
 2.1
1.6
 0.5
0.4
 1.4
0.6
 2.2
0.5
 1.3
0.6
 3.6
1.3
 1.7
1.3
 2.2
1.8
 0.2
0.2
 0.9
0.5
 0.0
0.0
 2.4
2.1
 1.1
0.6
 2.6


45 PTGS2 prostaglandin-endoperoxide synthase 2 442942 3.9 2.2
 1.8
 1.8
 2.4
 4.1
 5.1
 5.0
 4.9
 4.0
 4.0
 3.3
 3.7
 4.4
 4.1
 5.8
 5.0
 -0.8
 2.6
 3.2
 1.6
0.7
 6.6
3.1
 0.7
-0.3



46 RGS16 regulator of G protein signaling 16 100856402 3.8 2.1
3.0
 4.0
 4.7
 3.3
 3.0
 2.3
 3.4
 3.5
 1.6
 2.3
 3.1
 2.2
 2.0
 4.5
 -0.1
 1.5
 1.6
 2.4
 5.3
 1.8



47 LOC111093268 uncharacterized LOC111093268 111093268 3.8 2.1
























48 ARC activity regulated cytoskeleton associated protein 111098459 3.8 2.0
4.4
 3.9
 4.9
 4.5
 5.0
 7.6
 8.6
 8.5
 6.0
 9.4
 8.6
 1.6
 2.0
 3.7
 2.6
 1.4
 0.9






49 KLF10 Kruppel like factor 10 481992 3.8 2.4
 1.5
 2.1
 2.8
 6.3
 5.9
 6.9
 3.0
 4.0
 4.5
 1.7
 4.8
 5.7
 4.4
 5.6
 5.5
 -0.2
 -0.1
 -0.4






50 SPRY1 sprouty RTK signaling antagonist 1 483838 3.7 1.7
 2.4
 2.7
2.2
 2.8
2.7
 4.2
2.5
 3.7
3.4
 5.0
4.8
 3.7
3.1
 3.4
3.3
 6.0
4.9
 1.6
1.1
 5.1
4.1
 5.6
5.1
 2.0
0.5
 4.3
2.9
 4.0
2.7
 2.1
1.2
 1.9
1.2
 4.3
4.3
 3.3
0.8
 4.7
1.1
 2.5
2.2
 4.2


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