Orthologous genes in OrthoFinder**

Species Gene Description
 cfa-u.3   SPEN   spen family transcriptional repressor 
 cfa-r.3   SPEN   spen family transcriptional repressor 
 hsa-u.4   SPEN   spen family transcriptional repressor 
 mmu-u.4   Spen   spen family transcription repressor 
 rno-u.3   Spen   spen family transcriptional repressor 
 mcc-u.3   SPEN   spen family transcriptional repressor 
 gga-u.3   SPEN   spen family transcriptional repressor 
 dre-u.3   si:ch1073-335m2.2   si:ch1073-335m2.2 
 dre-u.3   spen   spen family transcriptional repressor 
 dme-u.3   spen   split ends 

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Top 50 coexpressed genes to SPEN (cfa-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 cfa310   Lysine degradation  8 57 7.55
 cfa4520   Adherens junction  3 66 2.89
 cfa4919   Thyroid hormone signaling pathway  3 114 2.22
 cfa4310   Wnt signaling pathway  3 162 -
 cfa5016   Huntington disease  3 341 -

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cfa:SPEN (spen family transcriptional repressor) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

cfa-u.3
for
SPEN
cfa-r.3
for
SPEN
hsa-u.4
for
SPEN
mmu-u.4
for
Spen
rno-u.3
for
Spen
mcc-u.3
for
SPEN
gga-u.3
for
SPEN
dre-u.3
for
si:ch1073-335m2.2
dre-u.3
for
spen
dme-u.3
for
spen
1 EP300 E1A binding protein p300 100684945 12.6 6.7
 10.8
10.2
 8.0
7.7
 9.4
8.9
 9.5
8.6
 12.0
6.3
 9.7
8.6
 7.1
5.4
 7.2
2 BRD4 bromodomain containing 4 484869 12.0 6.3
 8.1
5.5
 8.3
5.0
 9.0
5.7
 6.6
4.7
 7.9
4.9
 7.8
3.5
 3.8
1.7
 7.7
0.3
3 CREBBP CREB binding protein 479866 10.6 5.6
 10.8
10.2
 8.0
7.7
 9.4
8.9
 9.5
8.6
 12.0
6.3
 9.7
8.6
 7.1
5.4
 7.2
4 BAZ2A bromodomain adjacent to zinc finger domain 2A 481116 10.0 5.3
 6.8
 5.5
2.4
 5.9
2.3
 6.0
1.5
 5.4
3.4
 6.5
3.8
 5.1
4.0
 5.5
5 KMT2D lysine methyltransferase 2D 486558 9.7 5.1
 11.0
 8.4
 9.8
 6.0
 3.7
 5.6
 6.4
6 UBR4 ubiquitin protein ligase E3 component n-recognin 4 478211 9.4 5.0
 9.6
 9.3
 4.6
 4.8
 4.7
 4.0
 4.0
 6.7
7 PRRC2C proline rich coiled-coil 2C 480075 9.4 5.0
 9.0
 5.1
 1.2
 7.2
4.8
 0.8
8 EP400 E1A binding protein p400 486227 8.9 4.7
 10.0
 7.1
 8.9
 4.5
 11.5
 7.1
 1.6
9 KMT2A lysine methyltransferase 2A 479417 8.7 4.6
 9.6
 9.4
 9.5
 7.1
 8.3
 6.9
 7.1
10 DYNC1H1 dynein cytoplasmic 1 heavy chain 1 480437 8.6 4.5
 6.1
 5.3
 5.0
 3.6
 4.0
 2.8
 0.9
 2.9
11 NCOA6 nuclear receptor coactivator 6 477202 8.6 4.5
 8.6
 6.9
 7.2
 7.5
 4.4
 6.6
 2.7
 7.4
12 HCFC1 host cell factor C1 492246 8.5 4.5
 5.7
 5.8
 6.7
 4.3
4.0
2.5
 3.0
2.0
13 ANKRD11 ankyrin repeat domain 11 489658 8.5 4.5
 4.9
 6.2
 7.6
 7.6
 11.2
 2.7
 4.2
14 YLPM1 YLP motif containing 1 480387 7.9 4.2
 7.4
 4.5
 7.1
 7.0
 9.1
 3.4
 1.7
 3.6
15 HECTD4 HECT domain E3 ubiquitin protein ligase 4 477486 7.5 4.0
 6.4
 7.1
 6.2
 3.0
 2.9
 1.8
 0.8
16 KMT2B lysine methyltransferase 2B 100688666 7.5 4.0
 6.2
 7.7
 7.0
 4.3
9.3
4.4
 6.5
6.4
 11.3
17 BPTF bromodomain PHD finger transcription factor 480467 7.4 3.9
 6.3
 7.0
 9.1
 6.2
 10.4
 9.5
 4.7
 7.5
18 KMT2E lysine methyltransferase 2E (inactive) 475895 7.4 3.9
 6.6
 5.3
 9.8
 8.4
 6.3
 3.0
 4.1
 11.5
19 NCOR1 nuclear receptor corepressor 1 479515 7.4 3.9
 5.5
4.5
 7.4
4.4
 6.2
3.9
 3.7
3.5
 6.5
4.1
 5.4
4.4
 4.7
1.9
 8.9
20 ANKRD17 ankyrin repeat domain 17 475174 7.2 3.8
 6.8
3.3
 4.8
4.6
 6.1
4.3
 6.9
6.2
 6.1
4.6
 6.3
 3.5
 11.9
21 SETD1B SET domain containing 1B, histone lysine methyltransferase 486257 7.2 3.8
 7.9
6.2
 11.8
4.5
 12.6
6.1
 4.7
4.0
 7.4
2.1
 6.9
5.9
 7.5
5.1
 5.6
22 CHD8 chromodomain helicase DNA binding protein 8 475401 7.2 3.8
 5.9
5.2
 4.0
3.3
 4.3
3.8
 3.7
3.3
 5.7
4.6
 8.6
6.0
 5.2
4.0
 11.2
23 SETD2 SET domain containing 2, histone lysine methyltransferase 476643 7.1 3.8
 9.3
 3.6
 5.4
 9.0
 5.3
 10.5
 4.9
 2.3
24 KMT2C lysine methyltransferase 2C 611094 7.1 3.8
 10.4
 5.3
 5.9
 7.5
 8.9
 4.3
3.2
 6.7
4.6
 2.7
25 SMG7 SMG7 nonsense mediated mRNA decay factor 480035 7.1 3.7
 6.3
 4.9
 4.6
 4.2
 4.3
 5.0
 1.8
26 ZMIZ1 zinc finger MIZ-type containing 1 489063 6.9 3.7
 5.9
2.9
 5.0
4.3
 6.5
4.9
 3.1
1.4
 3.1
1.9
 3.5
2.3
 4.4
2.2
 3.2
27 GATAD2B GATA zinc finger domain containing 2B 490453 6.9 3.7
 7.7
3.9
 5.7
2.9
 6.1
2.3
 3.4
3.2
 3.6
3.0
 2.4
1.8
 1.6
1.3
 2.4
28 TNRC18 trinucleotide repeat containing 18 489882 6.9 3.7
 3.6
 6.7
 6.1
 4.5
 3.9
 5.6
 5.5
29 ASH1L ASH1 like histone lysine methyltransferase 480128 6.9 3.6
3.3
 3.9
 4.9
 8.7
 5.4
 8.1
 2.6
30 NIPBL NIPBL cohesin loading factor 489226 6.8 3.6
 6.2
 4.5
 5.3
 6.4
 4.5
1.8
 6.2
5.2
 2.6
2.1
 2.0
31 HNRNPUL2 heterogeneous nuclear ribonucleoprotein U like 2 476053 6.8 3.6
 3.9
3.3
 3.2
2.2
 4.9
2.5
 4.5
4.2
 3.8
3.8
 2.2
1.7
 1.6
1.3
 2.0
32 BICRA BRD4 interacting chromatin remodeling complex associated protein 612119 6.6 3.5
 4.2
 5.2
 7.9
 4.4
 2.3
 6.3
0.4
 3.7
1.0
 8.0
33 SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2 481107 6.6 3.5
 4.3
4.3
 3.9
2.5
 2.3
1.6
 4.0
3.7
 5.2
4.0
 4.3
1.8
 4.7
1.9
 0.2
34 FAM193A family with sequence similarity 193 member A 610546 6.6 3.5
 6.8
 6.0
 8.1
 5.1
 5.3
 6.0
 5.0
35 KAT6A lysine acetyltransferase 6A 100683464 6.5 3.5
 6.6
 6.3
 6.8
 5.5
 7.6
 6.5
 6.2
36 LOC479773 Snf2 related CREBBP activator protein 479773 6.5 3.5
 10.8
 6.6
 8.1
 5.8
6.4
 5.3
 3.8
37 BAZ1B bromodomain adjacent to zinc finger domain 1B 479719 6.5 3.4
 5.8
 3.0
 4.7
 7.3
 4.9
 4.5
 2.5
38 BOD1L1 biorientation of chromosomes in cell division 1 like 1 479089 6.4 3.4
 5.7
 3.4
 5.2
 5.3
 6.6


39 ZCCHC2 zinc finger CCHC-type containing 2 476180 6.4 3.4
 4.0
 1.9
3.3
 3.3
 1.7
 1.2
40 SCAF4 SR-related CTD associated factor 4 100687160 6.4 3.4
 7.8
4.4
 5.7
3.5
 8.9
2.9
 7.0
5.4
 5.2
3.9
 3.8
3.5
 0.8
0.4
 0.7
41 PTPN23 protein tyrosine phosphatase non-receptor type 23 609220 6.3 3.4
 4.6
 5.8
 5.0
 3.7
 2.2
 6.2
0.4
 2.8
2.7
 1.5
42 ZNF592 zinc finger protein 592 488751 6.3 3.3
 6.0
1.7
 4.7
1.7
 4.9
1.8
 3.7
1.2
 2.4
1.2
 4.9
3.5
 4.6
4.6
43 RBM33 RNA binding motif protein 33 611426 6.2 3.3
 6.2
 3.1
 2.0
 5.7
 5.7
 6.0
 4.8
44 WASF2 WASP family member 2 487343 6.2 3.3
 5.4
 3.5
 4.3
 5.0
 2.3
 2.0
 -0.3
45 UBE2O ubiquitin conjugating enzyme E2 O 483330 6.2 3.3
 3.1
 4.0
 3.1
 1.4
 3.8
 0.8
 1.6
 -0.4
46 POLR2A RNA polymerase II subunit A 479483 6.2 3.3
 6.4
 7.0
 7.4
 2.7
 4.6
 4.9
 1.3
 3.9
47 RREB1 ras responsive element binding protein 1 488206 6.1 3.2
 5.3
 2.0
 2.5
 3.6
 3.5
 2.6
1.8
 2.7
0.6
48 RBBP6 RB binding protein 6, ubiquitin ligase 479802 6.0 3.2
 3.3
 1.4
 5.1
 6.0
 7.5
 1.2
 1.3
 2.2
49 SON SON DNA and RNA binding protein 100856585 6.0 3.2
 5.5
 4.3
 1.8
 8.8
 4.0
 2.1
 1.2
 -1.7
50 PATL1 PAT1 homolog 1, processing body mRNA decay factor 609696 6.0 3.2
 4.2
-0.5
 3.1
 3.0
 3.3
0.1
 0.6
-1.5
 1.9
-0.7
 -0.7
-1.7
 1.2
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