Orthologous genes in OrthoFinder**

Species Gene Description
 spo-r.3   mkh1   MEK kinase (MEKK) Mkh1 
 spo-u.3   mkh1   MEK kinase (MEKK) Mkh1 
 spo-m.4   mkh1   MEK kinase (MEKK) Mkh1 
 spo-u.3   nak1   PAK-like kinase Nak1 
 spo-u.3   cdc7   serine/threonine protein kinase Cdc7 
 hsa-u.4   C3   complement C3 
 mmu-u.4   C3   complement component 3 
 rno-u.3   C3   complement C3 
 gga-u.3   C3   complement component 3 
 dre-u.3   100331492   complement C3 
 dre-u.3   c3a.4   complement C3a, tandem duplicate 4 
 dre-u.3   c3a.3   complement C3a, tandem duplicate 3 
 mcc-u.3   C3   complement C3 
 cfa-u.3   C3   complement C3 

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Top 50 coexpressed genes to mkh1 (spo-r.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 spo4138   Autophagy - yeast  3 69 2.47
 spo3430   Mismatch repair  4 22 -
 spo3030   DNA replication  3 35 -
 spo3420   Nucleotide excision repair  2 42 -
 spo3040   Spliceosome  2 89 -

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spo:mkh1 (MEK kinase (MEKK) Mkh1) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

spo-r.3
for
mkh1
spo-u.3
for
mkh1
spo-m.4
for
mkh1
spo-u.3
for
nak1
spo-u.3
for
cdc7
hsa-u.4
for
C3
mmu-u.4
for
C3
rno-u.3
for
C3
gga-u.3
for
C3
dre-u.3
for
100331492
dre-u.3
for
c3a.4
dre-u.3
for
c3a.3
mcc-u.3
for
C3
cfa-u.3
for
C3
1 cdc17 ATP-dependent DNA ligase Cdc17 2541849 SPAC20G8.01 4.0 4.4
 2.6
 1.1
0.2
 2.3
1.9
 -0.0
 0.2
 -0.1
 -0.8
 -0.7
-0.7
 -0.3
-0.5
 -0.1
-0.6
 -0.5
 0.4
2 sst2 AMSH-like ubiquitin-specific protease 2542606 SPAC19B12.10 3.6 4.2
 2.7
 2.8
 2.8
 -0.3
-1.6
 -0.1
-0.5
 0.2
-0.8
 0.1
0.1
 -0.2
-1.0
 0.5
-0.2
 0.1
-0.2
 -1.7
-2.3
 -0.0
-0.5
3 hsf1 transcription factor Hsf1 2541888 SPAC2E12.02 3.5 3.3
 1.2
 3.3
 2.0
 0.1
-0.1
 0.2
-0.3
 1.0
0.1
 0.1
-0.4
 0.8
-0.1
 -0.1
-0.4
 0.3
-0.5
 -0.1
-0.7
 0.2
-0.3
4 prp16 putative ATP-dependent RNA helicase Prp16 2540006 SPBC1711.17 3.4 3.8
 2.3
 2.2
0.4
 4.2
2.2
 0.2
0.2
 1.7
0.3
 1.1
0.9
 1.7
1.2
 2.3
2.1
 2.9
0.3
 1.4
0.8
 0.5
0.1
 0.3
-0.1
5 ppk30 Ark1/Prk1 family protein kinase Ppk30 2541109 SPBC6B1.02 3.3 4.3
 3.5
 2.3
1.4
 2.2
1.9
 0.5
0.3
 0.1
-0.5
 0.8
0.0
 1.5
0.2
 -0.1
-0.5
 0.9
0.0
 0.9
0.7
 1.0
-0.0
 0.0
-0.4
6 rev3 putative DNA polymerase zeta catalytic subunit Rev3 2543358 SPAC688.10 3.2 4.5
 4.2
 1.6
 1.9
 0.2
 -0.0
 -1.6
 -0.5
 -0.5
 0.8
 0.1
 -0.5
 -0.4
7 pst1 Clr6 histone deacetylase complex subunit Pst1 2540018 SPBC12C2.10c 3.2 3.3
 1.8
 2.8
0.9
 3.2
1.8








8 SPAC1002.12c putative succinate-semialdehyde dehydrogenase 2543267 SPAC1002.12c 3.1 2.9
 0.8
 3.0
-0.6
 1.7
0.3
 0.3
 -0.0
 -0.3
 -0.8
 0.5
 -0.9
 -0.6
 -0.8
 0.2
9 tsc1 hamartin 2541869 SPAC22F3.13 3.0 3.7
 2.8










10 SPBC29A3.03c putative ubiquitin-protein ligase E3 2540465 SPBC29A3.03c 3.0 2.8
 0.9
 1.1
 0.8
 0.4
-0.5
 0.1
-0.6
 -0.6
-0.8
 0.8
0.1
 -0.5
-0.6
 -0.7
-1.0
 0.4
-0.1
 -0.7
-1.3
 -0.0
-0.9
11 med15 mediator complex subunit Med15 2539712 SPBC146.01 3.0 3.7
 2.9
 2.7
 1.8








12 SPBC1604.12 hypothetical protein 2539702 SPBC1604.12 2.9 3.1
 1.8










13 rad4 BRCT domain protein Rad4 2543281 SPAC23C4.18c 2.9 3.2
 2.0
 1.6
 1.9
 -0.6
 -0.8
 0.8
 -0.1
 -0.2
 -0.5
 0.2
 -0.7
 -0.3
14 ino80 SNF2 family helicase Ino80 3361566 SPAC29B12.01 2.9 3.9
 3.6
 2.4
 3.3
 0.3
 -0.2
 -1.0
 -0.4
 1.0
 -0.7
 1.0
 -0.1
 0.5
15 SPAC11E3.05 ubiquitin-protein ligase E3 2541877 SPAC11E3.05 2.9 4.0
 3.7
 1.3
 2.5
 0.9
 -0.4
 0.0
 -1.1
 0.0
 0.5
 -0.7
 0.9
 -1.1
16 SPAC19A8.02 BAR and PH domain-containing protein 2542216 SPAC19A8.02 2.9 3.8
 3.4
 1.5
 1.7






0.8
17 rfc1 DNA replication factor C complex subunit Rfc1 2540426 SPBC23E6.07c 2.8 2.6
 0.7
 1.2
 3.2
 -0.5
 -0.1
 -0.4
 -1.1
 -0.1
 -0.2
 -0.9
 -0.7
 0.5
18 ubp15 ubiquitin hydrolase Ubp15 2541131 SPBC713.02c 2.8 2.6
 0.8
 1.4
0.6
 2.7
0.2
 -0.1
 0.4
 -0.7
 -0.6
 0.2
0.1
 1.2
0.3
 0.4
-0.2
 -0.3
19 SPAC32A11.02c hypothetical protein 2541700 SPAC32A11.02c 2.8 2.8
 1.2










20 aif1 flavoprotein 3361554 SPAC26F1.14c 2.8 3.4
 2.6
 1.5
 1.2
 -1.0
 -0.4
 -1.3
 1.0
-1.4
 -0.8
 -1.1
 -1.4
 1.1
 -0.5
21 dnm1 dynamin Dnm1 2540159 SPBC12C2.08 2.7 3.3
 2.4
 3.0
2.8
 1.7
-0.1
 2.3
0.4
 2.7
1.4
 0.5
-0.2
 0.9
0.4
 1.3
-0.1
 2.7
0.0
 2.2
-0.5
 0.8
0.6
 3.0
-0.7
22 res2 MBF transcription factor complex subunit Res2 2541871 SPAC22F3.09c 2.7 3.1
 2.1
 2.5
2.1
 1.8
1.7


-0.7
 -0.2
 -0.9
 -0.2

23 pst3 SIN3 family co-repressor Pst3 2539793 SPBC1734.16c 2.7 2.5
 0.8
 2.8
0.9
 3.2
1.8








24 SPAC11E3.02c C2 domain protein 2542968 SPAC11E3.02c 2.7 4.4
 4.8
 1.8
 2.2








25 ppk19 serine/threonine protein kinase Ppk19 2539996 SPBC119.07 2.7 3.3
 2.4
 4.4
 2.1
 0.5
 -0.5
 0.1
 -0.6
 0.1
 -0.9
 -0.9
 0.2
 -0.7
26 SPBC887.09c putative leucine-rich repeat protein Sog2 2541171 SPBC887.09c 2.7 4.2
 4.6
 3.7
 2.9








27 nca2 putative protein Nca2 2540670 SPBC4B4.02c 2.7 3.8
 3.6
 1.0
 1.9








28 sec2 putative guanyl-nucleotide exchange factor Sec2 2541930 SPAC23C4.10 2.7 2.6
 1.1
 2.8
 1.2
 -0.1
-0.3
 0.1
-0.8
 0.3
0.0
 -0.1
-0.2
 1.5
0.5
 1.8
1.5
 1.0
0.6
 0.7
0.6
 0.3
0.0
29 pep3 putative ubiquitin-protein ligase E3 2539053 SPCC790.02 2.7 3.0
 2.0
 0.6
 1.5
 -0.5
 -0.1
 -0.3
 -1.1
 -1.1
 -0.6
 -0.2
 -1.3
 0.6
30 atg7 ubiquitin-like conjugating enzyme Atg7 2540790 SPBC6B1.05c 2.7 2.4
 0.7
 2.3
 2.3
-0.8
 -1.2
 0.0
 0.5
 -0.4
 -0.9
 -0.8
 0.7
31 ubp5 ubiquitin hydrolase Ubp5 2539385 SPCC188.08c 2.6 3.5
 3.1
 1.4
0.6
 2.7
0.2
 -0.1
 0.4
 -0.7
 -0.6
 0.2
0.1
 1.2
0.3
 0.4
-0.2
 -0.3
32 spp1 DNA primase catalytic subunit Spp1 2543323 SPAC6B12.10c 2.6 2.4
 0.6
 2.2
 1.2
 -0.9
 0.1
 -1.2
 -0.2
 0.6
 0.5
 -0.3
 -1.4
 -0.3
33 msc1 multi-copy Chk1 suppressor 2541710 SPAC343.11c 2.6 3.2
 2.6










34 cyr1 adenylate cyclase 2540810 SPBC19C7.03 2.6 3.0
 2.1
 3.3
 1.7
 1.4
 -0.0
-0.1
 1.1
-1.1
 -0.2
-0.8
 -0.7
-0.8
 0.3
-0.5
 -0.6
-0.7
 1.5
-0.4
 0.6
35 SPBC25H2.03 putative phosphatidylinositol synthesis protein 2540489 SPBC25H2.03 2.6 3.2
 2.5
 2.9
 4.2
 -0.4
 -0.6
 0.2
-0.9
 -0.5
 0.4
 -0.1
 -2.1
 -1.0
 0.8
36 SPCC1235.03 SMR domain-containing protein 2539296 SPCC1235.03 2.6 3.4
 3.0










37 pms1 MutL family mismatch-repair protein Pms1 2542582 SPAC19G12.02c 2.5 2.5
 1.1
 0.9
 1.6
 0.6
 1.2
 0.3
 0.3
 1.6
1.5
 0.9
0.4
 3.1
2.5
 0.3
 0.4
38 SPBC16C6.04 hypothetical protein 2539754 SPBC16C6.04 2.5 3.2
 2.7










39 fsv1 SNARE Fsv1 2542946 SPAC6F12.03c 2.5 2.2
 0.5
 1.6
 -0.2
-1.4
 -1.0
 -1.0
 0.2
 -0.0
 0.0
 -0.6
40 mlh1 putative MutL family protein Mlh1 2539949 SPBC1703.04 2.5 2.5
 1.1
 0.9
 2.8
 -0.3
 -0.3
 -0.2
 0.1
 -1.0
 -0.3
 -0.6
 0.5
 0.5
41 SPCC1906.02c putative CUE domain-containing protein Cue3 2538764 SPCC1906.02c 2.5 3.1
 2.4
 2.9
 1.7








42 SPCC550.09 putative peroxin Pex32 2539457 SPCC550.09 2.5 2.9
 1.9
 2.3
 0.7








43 SPBC26H8.04c DEP domain protein 2540559 SPBC26H8.04c 2.5 3.2
 2.7
 0.9
 2.9
 -0.9
 0.5
 -0.7
 -0.9
 1.1
 -0.4
 -1.1
 -0.9
 0.4
44 pof12 F-box protein Pof12 2540914 SPBC56F2.01 2.5 2.9
 2.0










45 clr1 cryptic loci regulator Clr1 2540558 SPBC2D10.17 2.5 3.8
 4.0










46 SPAC637.13c putative cytoskeletal signaling protein 2543674 SPAC637.13c 2.5 3.6
 3.4
 1.7
 1.5








47 sec10 putative exocyst complex subunit Sec10 2542843 SPAC13F5.06c 2.5 3.1
 2.5
 0.9
 1.4
 -1.3
 0.5
 -1.1
 -1.3
 -0.3
 -1.0
 -0.6
 -0.4
 -1.2
48 prp1 U4/U6 x U5 tri-snRNP complex subunit Prp1 2541185 SPBC6B1.07 2.5 1.9
 -0.1
 0.3
 1.4
 2.2
 2.3
 1.4
 1.5
 -0.3
-1.1
 0.0
-0.6
 0.7
-0.1
 0.6
 -0.7
49 SPAC25B8.08 hypothetical protein 2542659 SPAC25B8.08 2.5 2.5
 1.2
 0.7
 0.6
 -0.1
-1.4
 -0.4
 -0.6
 1.0
-0.8
 -0.7
 0.1
 -1.3
 0.4
-1.2
 -0.0
-0.7
50 orc4 origin recognition complex subunit Orc4 2541298 SPBP23A10.13 2.5 2.9
 2.1










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