Orthologous genes in OrthoFinder**

Species Gene Description
 sce-m.4   HEM2   porphobilinogen synthase HEM2 
 sce-u.3   HEM2   porphobilinogen synthase HEM2 
 sce-r.3   HEM2   porphobilinogen synthase HEM2 
 spo-u.3   SPBP8B7.23   putative ubiquitin-protein ligase E3 
 hsa-u.4   ALAD   aminolevulinate dehydratase 
 mmu-u.4   Alad   aminolevulinate, delta-, dehydratase 
 rno-u.3   Alad   aminolevulinate dehydratase 
 gga-u.3   ALAD   aminolevulinate dehydratase 
 dre-u.3   alad   aminolevulinate dehydratase 
 dme-u.3   Pbgs   Porphobilinogen synthase 
 mcc-u.3   ALAD   aminolevulinate dehydratase 
 cfa-u.3   ALAD   aminolevulinate dehydratase 

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Top 50 coexpressed genes to HEM2 (sce-m.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 sce3010   Ribosome  9 173 4.83
 sce4213   Longevity regulating pathway - multiple species  2 38 -
 sce4146   Peroxisome  2 40 -
 sce1240   Biosynthesis of cofactors  2 131 -
 sce970   Aminoacyl-tRNA biosynthesis  2 338 -

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sce:HEM2 (porphobilinogen synthase HEM2) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

sce-m.4
for
HEM2
sce-u.3
for
HEM2
sce-r.3
for
HEM2
spo-u.3
for
SPBP8B7.23
hsa-u.4
for
ALAD
mmu-u.4
for
Alad
rno-u.3
for
Alad
gga-u.3
for
ALAD
dre-u.3
for
alad
dme-u.3
for
Pbgs
mcc-u.3
for
ALAD
cfa-u.3
for
ALAD
1 MRP4 mitochondrial 37S ribosomal protein MRP4 856384 YHL004W 2.9 4.7
 1.6
 0.6
 0.5
 0.1
 0.9
 -0.0
 0.6
 3.1
 0.3
 0.1
2 SCO1 Cu-binding protein SCO1 852325 YBR037C 2.8 4.9
 1.9
-1.2
 0.0
 0.9
 1.8
 2.1
0.8
 2.3
 1.1
 0.7
0.5
3 MRPL19 mitochondrial 54S ribosomal protein YmL19 855536 YNL185C 2.6 4.7
 2.0
-1.2
 1.8
 1.8
0.5
 0.1
 -0.7
 0.1
4 MRP1 mitochondrial 37S ribosomal protein MRP1 851948 YDR347W 2.4 3.6
 1.1








5 TUF1 translation elongation factor Tu 854359 YOR187W 2.4 5.0
 2.5
 -1.4
 0.2
 3.4
 3.2
0.5
 0.9
-0.4
 2.0
 1.4
6 MRPL10 mitochondrial 54S ribosomal protein YmL10/YmL18 855436 YNL284C 2.2 3.1
 0.8
 -0.7
 -0.2
 1.3
 0.9
 0.8
 1.2
 -0.7
 -0.2
 -0.7
7 TIM50 protein translocase subunit TIM50 856042 YPL063W 2.2 3.8
 1.6
 -0.9
 -1.8
 4.0
 5.2
 1.9
 -0.1
 2.3
-0.0
 1.0
 1.3
8 MAM33 Mam33p 854740 YIL070C 2.2 5.2
 2.9
 -0.1







9 MSS51 Mss51p 850900 YLR203C 2.1 3.7
 1.4








10 MCP2 Mcp2p 850955 YLR253W 2.1 3.6
 1.4
 0.2
1.2
 1.5
 1.7
 2.3
 4.1
 0.8
 0.9
11 MRX15 Mrx15p 855776 YNR040W 2.1 3.7
 1.5








12 MRPL36 mitochondrial 54S ribosomal protein YmL36 852419 YBR122C 2.1 2.9
 0.8








13 TIM23 protein transporter TIM23 855751 YNR017W 2.0 5.2
 3.0
-0.6
-1.6
 0.1
 1.5
 1.3
 -0.5
 0.2
 0.3
 1.2
14 RML2 mitochondrial 54S ribosomal protein RML2 856660 YEL050C 2.0 3.3
 1.1
 0.0
 0.3
 4.5
 4.1
 2.2
 -0.0
 2.3
 3.4
 1.7
15 MRPS28 mitochondrial 37S ribosomal protein MRPS28 851937 YDR337W 2.0 3.8
 1.7
 -1.2
 -1.4
 2.6
 2.1
 -0.6
 1.2
 1.4
 0.9
 2.0
16 TIM44 protein translocase subunit TIM44 854790 YIL022W 2.0 2.8
 0.7
 -0.9
 -1.4
 1.6
 0.0
 -0.1
 0.8
 0.9
 0.3
 0.5
17 MRPL11 mitochondrial 54S ribosomal protein YmL11 851325 YDL202W 2.0 3.2
 1.2








18 MAS2 mitochondrial-processing protease subunit alpha 856419 YHR024C 2.0 3.7
 1.6
 0.9
 3.0
 1.7
 1.9
 1.9
 1.9
 2.7
 1.2
 1.6
19 MRPL35 mitochondrial 54S ribosomal protein YmL35 851921 YDR322W 2.0 5.3
 3.2
 -0.3







20 YFH7 Yfh7p 850558 YFR007W 1.9 3.1
 1.1
 -0.5







21 TOM20 Tom20p 852973 YGR082W 1.9 4.2
 2.1
 -0.2
 -0.1
 -0.5
 -1.4
-1.4
 -1.1
 0.2
0.2
 -0.1
-0.3
 -2.0
 -1.1
22 PAP1 polynucleotide adenylyltransferase PAP1 853871 YKR002W 1.9 2.1
 0.2
-1.0
-1.3
 0.0
-1.4
 -0.3
-0.5
 -0.7
-0.7
 1.1
0.2
 -1.9
 -1.2
-1.3
 -0.8
-0.9
23 NAM9 mitochondrial 37S ribosomal protein NAM9 855585 YNL137C 1.9 4.2
 2.1








24 ABZ1 4-amino-4-deoxychorismate synthase 855768 YNR033W 1.9 3.2
 1.2








25 NAT2 Nat2p 853050 YGR147C 1.9 3.6
 1.6
 -0.6







26 MRPL20 mitochondrial 54S ribosomal protein YmL20 853960 YKR085C 1.9 2.6
 0.7








27 SAM37 SAM complex subunit SAM37 855082 YMR060C 1.9 3.0
 1.1








28 RSM24 mitochondrial 37S ribosomal protein RSM24 851755 YDR175C 1.9 3.8
 1.8
 0.9







29 MNP1 mitochondrial nucleoid protein MNP1 852811 YGL068W 1.9 4.9
 2.9
 0.9
 -0.4
 3.3
 2.2
 3.3
 1.4
 0.3
 0.9
 1.6
30 MSK1 lysine--tRNA ligase MSK1 855651 YNL073W 1.9 3.7
 1.7








31 RSM25 mitochondrial 37S ribosomal protein RSM25 854715 YIL093C 1.9 4.3
 2.3
 -1.3







32 MGR2 Mgr2p 856006 YPL098C 1.8 3.4
 1.5
 2.2
 0.2
 0.9
 1.9
 1.5
 1.6
 -0.4
 1.9
 0.6
33 PCP1 rhomboid protease PCP1 852993 YGR101W 1.8 3.5
 1.5
 -2.0
 -0.8
 0.2
 1.3
 0.1
 1.8
-0.3
 3.1
 0.4
 0.3
34 RSM26 mitochondrial 37S ribosomal protein RSM26 853565 YJR101W 1.8 3.7
 1.8
 -1.0







35 SCT1 bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase SCT1 852271 YBL011W 1.8 3.0
 1.2
 -0.1







36 PPA2 inorganic diphosphatase PPA2 855309 YMR267W 1.8 3.1
 1.3








37 MSE1 glutamate--tRNA ligase MSE1 854124 YOL033W 1.8 3.2
 1.3
-0.0
 0.3
0.3
 0.9
 1.0
 1.8
 0.4
38 EHD3 3-hydroxyisobutyryl-CoA hydrolase 851606 YDR036C 1.8 4.0
 2.1
 0.1
 1.5
 1.1
 0.5
 2.4
 1.6
 4.0
 0.3
 1.5
39 FET5 ferroxidase FET5 850502 YFL041W 1.8 2.4
 0.5





1.5
1.0

40 MIX17 Mix17p 855014 YMR002W 1.8 3.0
 1.2








41 MRPL3 mitochondrial 54S ribosomal protein YmL3 855039 YMR024W 1.8 3.5
 1.6
 3.4
 -1.2
 0.6
 0.2
 -1.0
 1.7
 0.4
 0.5
 0.0
42 MRPL24 mitochondrial 54S ribosomal protein YmL24/YmL14 855231 YMR193W 1.8 3.6
 1.7
-0.4
 5.7
 2.8
 1.9
 1.0
 1.1
 1.5
 2.0
43 MRPS18 mitochondrial 37S ribosomal protein YmS18 855410 YNL306W 1.8 3.0
 1.1








44 MRP13 mitochondrial 37S ribosomal protein YmS-A 852975 YGR084C 1.8 3.5
 1.6








45 YTA12 m-AAA protease subunit YTA12 855114 YMR089C 1.8 3.1
 1.2
1.0
0.4
 2.3
1.4
 2.3
0.4
 2.3
0.5
 1.4
1.2
 2.0
1.3
 1.7
0.3
 1.0
0.1
46 UBP16 putative ubiquitin-specific protease UBP16 856032 YPL072W 1.7 2.2
 0.4
-1.6
 0.3
-1.5
 -0.5
-0.9
 -0.6
-1.7
 1.3
-0.6
 0.1
 -0.9
 -0.2
47 MTM1 Mtm1p 853173 YGR257C 1.7 2.7
 0.9
 1.5
 1.3
0.4
 3.6
0.4
 3.7
-0.6
 2.5
 1.8
0.5
 -0.5
 1.6
-1.4
 2.0
0.4
48 RSM7 mitochondrial 37S ribosomal protein RSM7 853578 YJR113C 1.7 3.7
 1.9
 2.3
 -1.5
 3.2
 2.1
 1.3
 0.8
 0.2
 0.6
 0.6
49 SSC1 Hsp70 family ATPase SSC1 853503 YJR045C 1.7 3.0
 1.3
0.7
0.4
 0.5
0.4
 0.1
-0.2
 1.0
-0.8
 1.0
0.1
 2.4
2.1
 2.0
0.5
 1.4
0.9
50 MRPS35 mitochondrial 37S ribosomal protein MRPS35 853075 YGR165W 1.7 3.7
 1.9








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