Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-r.6   PSAP   prosaposin 
 hsa-u.4   PSAP   prosaposin 
 hsa-m.7   PSAP   prosaposin 
 hsa-m2.4   PSAP   prosaposin 
 hsa-u.4   PSAPL1   prosaposin like 1 
 mcc-u.3   PSAP   prosaposin 
 mmu-u.4   Psap   prosaposin 
 mmu-u.4   Psapl1   prosaposin-like 1 
 rno-u.3   Psap   prosaposin 
 cfa-u.3   PSAP   prosaposin 
 gga-u.3   423719   proactivator polypeptide-like 
 gga-u.3   PSAP   prosaposin 
 dre-u.3   psap   prosaposin 
 dme-u.3   Sap-r   Saposin-related 
 cel-u.3   spp-8   SaPosin-like Protein family 
 cel-u.3   spp-10   SaPosin-like Protein family 

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Top 50 coexpressed genes to PSAP (hsa-r.6 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa4142   Lysosome  27 124 7.09
 hsa511   Other glycan degradation  7 15 7.02
 hsa4140   Autophagy - animal  6 133 5.56
 hsa4145   Phagosome  5 140 4.21
 hsa4141   Protein processing in endoplasmic reticulum  6 159 3.95

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hsa:PSAP (prosaposin) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-r.6
for
PSAP
hsa-u.4
for
PSAP
hsa-m.7
for
PSAP
hsa-m2.4
for
PSAP
hsa-u.4
for
PSAPL1
mcc-u.3
for
PSAP
mmu-u.4
for
Psap
mmu-u.4
for
Psapl1
rno-u.3
for
Psap
cfa-u.3
for
PSAP
gga-u.3
for
423719
gga-u.3
for
PSAP
dre-u.3
for
psap
dme-u.3
for
Sap-r
cel-u.3
for
spp-8
cel-u.3
for
spp-10
1 GRN granulin precursor 2896 21 13.2 12.8
 4.8
 9.3
 -0.9
 9.1
 9.8
 -1.2
 8.0
 8.9

2.7
2.4
1.7
 2.7
2 CTSD cathepsin D 1509 10 12.3 11.6
 4.7
 8.2
 2.2
2.0
 6.2
1.0
 9.9
0.6
 2.0
1.3
 11.5
0.6
 7.0
0.1
 1.7
1.5
 5.6
0.2
 8.1
2.8
 9.8
0.3
 6.4
6.4
 5.0
2.5
3 GNS glucosamine (N-acetyl)-6-sulfatase 2799 1 10.9 11.3
 4.8
 9.0
 -0.6
 5.6
 8.1
 -0.7
 6.5
 6.2
 0.4
 5.0
 5.1
1.7
 0.2

4 PLD3 phospholipase D family member 3 23646 0 10.4 9.9
 3.2
 7.0
 -0.7
 4.1
 7.3
 -0.3
 6.0
 7.1
 1.6
 1.0
 0.9
 5.2
 4.4
-0.3
 1.3
-1.2
5 ATP6AP1 ATPase H+ transporting accessory protein 1 537 0 9.8 8.4
 3.7
 5.1
 -0.8
 8.7
 9.2
 -0.5
 7.9
-0.1
 6.3
 -0.3
-0.4
 3.3
-0.5
 3.2
0.0
 3.9
-0.6
 -0.1
 -1.2
6 CTSB cathepsin B 1508 0 9.6 8.7
 3.2
 5.7
 -0.8
 9.5
 10.9
 -0.8
 8.5
 7.8
 0.1
 6.9
 4.1
1.1
 10.7
 4.4
2.5
 1.4
0.5
7 HEXA hexosaminidase subunit alpha 3073 4 9.5 10.1
 3.2
 8.2
 -0.1
-0.6
 9.4
5.2
 8.2
4.4
 -0.4
-1.4
 6.2
4.6
 4.8
4.5
 1.1
-0.2
 3.3
1.7
 2.8
1.7
 2.4
1.9
 1.7
 3.3
8 OS9 OS9 endoplasmic reticulum lectin 10956 0 8.9 9.8
 3.4
 8.3
 -0.8
 7.4
 3.5
 -0.6
 3.4
 5.6
 0.1
 1.7
 -0.6


9 TPP1 tripeptidyl peptidase 1 1200 2 8.8 8.9
 3.8
 6.9
 -0.8
 5.2
 4.3
 -0.4
 7.7
 6.0
 0.6
 2.7
 7.4


10 APLP2 amyloid beta precursor like protein 2 334 1 8.6 8.4
 3.5
 6.2
 0.9
-0.9
 6.9
3.8
 5.6
4.2
 -0.3
-0.5
 5.7
5.1
 4.1
1.6
 1.2
-0.3
 6.8
3.2
 2.0
0.3
 -0.4
 1.0
 2.6
11 NPC2 NPC intracellular cholesterol transporter 2 10577 5 8.4 7.8
 2.6
 5.3
 0.2
 7.3
 6.1
 -1.1
 6.5
 4.2
 0.6
 4.5
 6.1
1.2
 2.7

12 CTSA cathepsin A 5476 2 8.2 7.6
 3.3
 5.2
 -0.3
 5.8
 8.3
 -0.5
 8.9
 7.8
 -0.2
 4.0
 6.0
3.3
5.2
2.6
 6.4
2.5
13 ASAH1 N-acylsphingosine amidohydrolase 1 427 2 8.1 8.3
 3.4
 6.4
 -0.3
 3.9
 4.6
 -0.6
 4.5
 3.4
 0.9
 5.5
 3.7
2.4
16.8
 3.4
14 SCPEP1 serine carboxypeptidase 1 59342 1 8.0 7.5
 2.1
 5.2
 -0.3
 4.7
 5.4
 -0.6
 5.7
 5.4
 -0.4
 4.6
 4.8
 0.3
-0.2
 5.0
 7.6
15 ATP6AP2 ATPase H+ transporting accessory protein 2 10159 1 7.8 6.8
 2.8
 4.2
 -0.2
 4.3
 6.2
 -1.0
 3.7
 4.8
 0.2
 5.0
 1.5
 3.2
 1.5
 1.3
16 DNASE2 deoxyribonuclease 2, lysosomal 1777 0 7.6 6.9
 2.9
 4.5
 -0.5
 1.7
 2.6
 0.1
 3.8
 3.1

1.9
 1.3
 5.7
-0.6
 2.5
1.8
17 LAMP1 lysosomal associated membrane protein 1 3916 1 7.5 7.2
 3.6
 5.0
 0.2
-0.6
 7.1
3.6
 6.8
3.7
 -0.0
-0.4
 7.5
4.5
 6.8
6.6
 -0.2
-0.8
 5.3
3.8
 6.7
4.3
 7.5
 2.9
 3.1
0.3
18 GLB1 galactosidase beta 1 2720 7 7.5 7.3
 3.3
 5.2
 0.0
-0.7
 6.5
0.7
 4.8
1.5
 -0.7
-1.0
 5.6
2.0
 3.4
1.2
 0.5
0.5
 4.3
0.5
 4.1
0.7
 1.9
1.6
 0.1
 4.2
19 MAN2B1 mannosidase alpha class 2B member 1 4125 1 7.5 7.5
 2.6
 5.7
 -1.1
 6.4
 6.5
 -0.8
 4.6
 6.6

6.0
 5.0
3.2
 0.2
 1.1
20 NUCB1 nucleobindin 1 4924 0 7.4 6.4
 2.2
 3.9
 -0.1
-0.5
 5.9
0.8
 3.4
1.7
 0.2
-1.2
 5.5
1.3
 4.4
-0.9
 0.4
 2.2
 3.1
1.1
 5.2
 -0.7
 0.8
21 DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit 1650 2 7.2 6.5
 3.0
 4.3
 -0.3
 5.2
 2.1
 -0.6
 4.0
 3.3
 -0.2
 3.0
 0.1
 1.2
 0.1
 0.9
22 TMBIM6 transmembrane BAX inhibitor motif containing 6 7009 0 6.8 6.0
 2.8
 3.7
 -0.9
 1.9
 3.6
 -0.4
 4.9
 3.0
 -0.2
 1.8
 2.3
 1.6

23 LAMP2 lysosomal associated membrane protein 2 3920 2 6.8 6.7
 2.6
 4.9
 0.2
-0.6
 7.1
3.6
 6.8
3.7
 -0.0
-0.4
 7.5
4.5
 6.8
6.6
 -0.2
-0.8
 5.3
3.8
 6.7
4.3
 7.5
 2.9
 3.1
0.3
24 LRPAP1 LDL receptor related protein associated protein 1 4043 1 6.7 5.9
 1.6
 3.8
 0.1
 2.7
 4.7
 -1.3
 4.7
 5.0
 -0.3
 3.9
 -0.2
 3.4
 -0.5
 -0.3
25 HEXB hexosaminidase subunit beta 3074 2 6.7 6.6
 2.8
 5.0
 -0.1
-0.6
 9.4
5.2
 8.2
4.4
 -0.4
-1.4
 6.2
4.6
 4.8
4.5
 1.1
-0.2
 3.3
1.7
 2.8
1.7
 2.4
1.9
 1.7
 3.3
26 LGMN legumain 5641 0 6.5 6.3
 2.2
 4.6
 -0.6
 6.2
 7.0
 -0.6
 7.1
 6.5
 -0.2
 5.0
 3.6
2.3
 2.9
27 PIGT phosphatidylinositol glycan anchor biosynthesis class T 51604 0 6.4 6.2
 1.6
 4.5
 -0.6
 2.3
 3.0
 -0.6
 5.9
 4.3
 0.8
 1.9
 -1.9
 3.3
 0.4
 0.4
28 NEU1 neuraminidase 1 4758 1 6.4 6.3
 2.6
 4.6
 -0.6
 5.3
 3.2
 -1.0
 3.2
 1.0

4.4


29 RPN2 ribophorin II 6185 0 6.4 5.8
 1.8
 3.9
 0.1
 5.8
 4.1
 -0.4
 5.4
 3.2
 0.0
 3.0
 0.7
 3.8
 -0.0
 0.4
30 PLA2G15 phospholipase A2 group XV 23659 0 6.3 5.2
 1.4
 2.9
 0.5
-0.3
 3.3
0.1
 6.2
-0.5
 -0.4
-1.0
 3.3
-0.5
 1.6
1.2
 1.5
-0.4
 2.2
1.8
 2.1
0.9
 4.3
2.1
 -0.4
 5.3
31 SQSTM1 sequestosome 1 8878 0 6.2 5.9
 1.2
 4.1
 -0.4
 3.1
 4.7
 -1.0
 2.4
 2.6
 1.4
 1.0
 2.7
 5.3
 2.6
2.0
 2.0
0.9
32 ERP29 endoplasmic reticulum protein 29 10961 0 6.2 5.8
 2.4
 3.9
 -0.3
4.1
 0.3
 3.9
 1.6
 0.8
 3.1
0.1

33 ATP6V0D1 ATPase H+ transporting V0 subunit d1 9114 0 6.1 5.1
 2.6
 2.8
 0.0
-0.4
 4.8
1.1
 4.2
2.0
 0.1
-0.5
 4.3
0.2
 4.1
1.7
 0.7
-0.7
 2.1
-0.1
 0.6
 3.7
0.5
 1.0
 0.2
34 GLG1 golgi glycoprotein 1 2734 0 6.1 5.8
 2.3
 4.2
 0.1
 3.8
 4.6
 -0.9
 3.2
 2.4
 0.3
 1.3
 2.2
 3.7
 -0.3
 -0.6
35 GLMP glycosylated lysosomal membrane protein 112770 0 6.0 5.0
 1.7
 2.7
 -0.4
 5.0
 6.2
 -0.8
 4.8
 2.5
 0.9
 2.2
 2.2


36 BCAP31 B cell receptor associated protein 31 10134 0 6.0 4.9
 2.4
 2.6
 0.0
-0.9
 3.8
-0.7
 2.3
1.1
 0.8
-0.3
 4.1
0.7
 2.4
-0.9
 0.7
0.5
 2.7
1.5
 3.2
0.4
 3.3
 0.7
 2.4
37 CD63 CD63 molecule 967 1 5.9 5.3
 2.8
 3.3
 -0.4
 2.6
 3.0
 -0.9
 2.9
 3.7
 1.8
 2.4
 2.9
 1.4
0.1
 -0.7
 -1.8
38 PLBD2 phospholipase B domain containing 2 196463 0 5.9 5.6
 1.5
 3.9
 -0.6
 2.6
 4.7
 -1.3
 5.9
 5.4
 0.6
 2.1
 2.8
1.7
1.6
 6.7
1.1
39 PPT1 palmitoyl-protein thioesterase 1 5538 1 5.9 6.2
 1.3
 4.9
 -0.5
 7.2
 6.3
 -0.8
 6.5
 3.8
 0.5
 4.5
 4.3
 2.2
 -0.4
 4.1
40 ERGIC3 ERGIC and golgi 3 51614 0 5.9 5.2
 2.1
 3.3
 0.2
 5.3
 3.0
 -0.5
 3.6
 3.1
 -0.2
 3.4
 -0.0
 -0.3
 -0.7
 -0.1
41 CD68 CD68 molecule 968 0 5.9 5.3
 1.0
 3.5
 -0.5
 4.8
 3.5
 -0.7
 1.6
 3.5





42 GNPTG N-acetylglucosamine-1-phosphate transferase subunit gamma 84572 0 5.8 5.5
 2.0
 3.8
 -0.7
 0.9
 2.0
 0.0
 3.1
 3.2
 0.3
 1.8
 0.4


43 FUCA1 alpha-L-fucosidase 1 2517 0 5.7 5.4
 1.7
 3.8
 0.1
-0.2
 4.6
2.2
 5.0
3.6
 -0.3
-0.6
 7.4
3.5
 4.0
2.1
 0.1
-0.1
 3.0
2.0
 5.1
4.4
-0.7
 3.1
44 LRP1 LDL receptor related protein 1 4035 0 5.7 5.0
 1.2
 3.1
 -0.1
-0.4
 7.0
0.8
 3.3
-0.3
 -0.3
-0.9
 4.5
0.2
 4.5
0.5
 0.7
0.2
 1.3
0.3
 1.8
0.5
 2.3
 0.3
 1.6
45 GM2A GM2 ganglioside activator 2760 7 5.7 6.1
 2.7
 5.0
 -0.4
 3.9
 6.3
 -0.6
 4.3
 2.6
 -0.3
 0.8
 5.4


46 MANBA mannosidase beta 4126 0 5.7 5.7
 2.1
 4.4
 -0.2
 2.7
 2.6
 -0.2
 2.6
 4.1
 0.9
 2.5
 2.6
 4.6
 1.0
 0.4
47 CTSL cathepsin L 1514 0 5.6 5.6
 2.2
 4.1
 2.6
0.2
 1.8
0.5
 4.4
 -0.6
 3.2
 3.1
 0.5
 3.1
 5.1
1.7
 7.3
 0.4
 5.7
48 BSG basigin (Ok blood group) 682 0 5.6 5.7
 2.2
 4.5
 0.2
 2.9
1.8
 3.6
3.5
 -0.1
-0.5
 4.2
2.3
 3.1
0.8
 1.8
-0.3
 3.2
3.0
 1.8
-0.9
 2.6

49 TCN2 transcobalamin 2 6948 0 5.6 4.8
 1.3
 2.9
 -0.6
 1.8
 3.2
 -0.9
 4.3
 2.8
 -0.5
 0.5
 1.6


50 GANAB glucosidase II alpha subunit 23193 0 5.6 5.5
 2.6
 4.2
 0.1
-0.1
 4.7
0.8
 2.4
0.5
 -0.1
-0.8
 4.0
0.4
 4.2
0.9
 0.1
 0.7
 0.8
0.6
 4.6
 0.3
-0.1
 2.0
0.4
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