Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-r.6   PTPN22   protein tyrosine phosphatase non-receptor type 22 
 hsa-u.4   PTPN22   protein tyrosine phosphatase non-receptor type 22 
 hsa-m.7   PTPN22   protein tyrosine phosphatase non-receptor type 22 
 hsa-m2.4   PTPN22   protein tyrosine phosphatase non-receptor type 22 
 mcc-u.3   PTPN22   protein tyrosine phosphatase non-receptor type 22 
 mmu-u.4   Ptpn22   protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 
 rno-u.3   Ptpn22   protein tyrosine phosphatase, non-receptor type 22 
 cfa-u.3   PTPN22   protein tyrosine phosphatase non-receptor type 22 
 gga-u.3   PTPN22   protein tyrosine phosphatase, non-receptor type 22 

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Top 50 coexpressed genes to PTPN22 (hsa-r.6 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa4650   Natural killer cell mediated cytotoxicity  7 94 6.45
 hsa4514   Cell adhesion molecules  4 131 2.15
 hsa4810   Regulation of actin cytoskeleton  5 218 -
 hsa4014   Ras signaling pathway  3 232 -
 hsa4010   MAPK signaling pathway  3 294 -

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hsa:PTPN22 (protein tyrosine phosphatase non-receptor type 22) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-r.6
for
PTPN22
hsa-u.4
for
PTPN22
hsa-m.7
for
PTPN22
hsa-m2.4
for
PTPN22
mcc-u.3
for
PTPN22
mmu-u.4
for
Ptpn22
rno-u.3
for
Ptpn22
cfa-u.3
for
PTPN22
gga-u.3
for
PTPN22
1 PTPRC protein tyrosine phosphatase receptor type C 5788 26 8.8 7.7
 3.6
 4.8
 5.0
 5.2
 5.0
 5.0
 4.6
2 SLAMF6 SLAM family member 6 114836 0 7.7 7.8
 1.9
 6.0
 5.7
5.4
 4.1
2.5
 5.1
1.8
 3.1
2.4
3 CD84 CD84 molecule 8832 0 6.8 5.4
 2.6
 2.7
 5.7
5.4
 4.1
2.5
 5.1
1.8
 3.1
2.4
4 PTPN7 protein tyrosine phosphatase non-receptor type 7 5778 13 6.2 5.2
 2.9
 3.0
 3.3
-1.2
 3.0
1.5
 3.2
0.1
 2.2
-0.5
 4.0
0.7
5 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 5294 0 6.2 6.0
 3.5
 4.4
 3.9
 2.1
 2.3
 2.0
 0.6
6 PYHIN1 pyrin and HIN domain family member 1 149628 0 5.8 5.8
 3.5
 4.3
 5.6
1.2
 3.0
2.9
 1.5
 0.6
0.5
7 LPXN leupaxin 9404 0 5.6 5.7
 2.5
 4.4
 5.0
1.3
 5.4
1.8
 3.4
0.0
 2.2
0.3
 3.7
1.9
8 SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 64092 0 5.4 5.7
 2.9
 4.6
 2.5
 2.5
 2.6
 2.0
 2.4
9 GPR174 G protein-coupled receptor 174 84636 0 5.3 6.4
 2.9
 5.9
 4.5
 3.9
0.2
 4.2
10 TMEM156 transmembrane protein 156 80008 0 5.3 6.8
 2.5
 6.7
 4.8

2.5
 0.4
11 LAX1 lymphocyte transmembrane adaptor 1 54900 0 5.3 5.1
 3.0
 3.7
 4.9
 4.7
 3.7
 1.1
12 EVI2A ecotropic viral integration site 2A 2123 0 5.3 6.6
 3.7
 6.2
 2.9
 4.5
 2.6
 2.2
 2.1
13 TMEM71 transmembrane protein 71 137835 0 5.2 5.8
 2.9
 4.9
 3.2
 3.4
 3.2
 1.5
 -0.9
14 GPR65 G protein-coupled receptor 65 8477 0 5.2 6.7
 4.0
 6.6
 3.3
 5.7
2.8
15 CD96 CD96 molecule 10225 1 5.2 5.3
 3.0
 4.1
 4.4
 4.7
 5.8
 2.2
16 NCKAP1L NCK associated protein 1 like 3071 0 5.1 4.6
 1.4
 2.9
 3.0
-1.0
 3.1
-0.7
 2.7
-1.4
 4.1
-1.4
 2.0
-1.3
17 DOCK2 dedicator of cytokinesis 2 1794 0 5.1 4.7
 1.0
 3.2
 3.3
0.9
 5.3
1.4
 3.1
-0.0
 2.6
1.0
 2.6
2.4
18 EVI2B ecotropic viral integration site 2B 2124 0 5.1 5.9
 3.5
 5.2
 4.9
3.3
 1.4
 3.9
19 GFI1 growth factor independent 1 transcriptional repressor 2672 0 5.1 4.6
 2.8
 3.0
 5.4
 3.4
2.2
 3.4
20 KLRK1 killer cell lectin like receptor K1 22914 0 5.0 5.2
 2.5
 4.2
 6.2
 3.6
 5.7

21 SLFN12L schlafen family member 12 like 100506736 0 5.0 5.0

2.4
0.1
 0.7
0.2
 0.9

22 AP4B1 adaptor related protein complex 4 subunit beta 1 10717 0 4.9 4.8
 3.4
 3.5
 1.3
 1.3
 1.2
 2.0
 0.6
23 THEMIS thymocyte selection associated 387357 0 4.8 5.3
 2.6
 4.4
 3.3

1.3
 4.1
24 CD244 CD244 molecule 51744 0 4.8 4.2
 1.9
 2.6
 3.0
 2.9
3.1
 4.5
2.4
25 SLA2 Src like adaptor 2 84174 0 4.8 4.4
 1.8
 3.0
 4.5
 3.8
2.1
 0.1
26 CD200R1 CD200 receptor 1 131450 0 4.7 3.7
 2.1
 1.9
 4.5
 2.2
1.8
 1.5
 2.0
 0.9
27 TNFSF14 TNF superfamily member 14 8740 0 4.6 3.1
 1.7
 0.9
 1.5
 2.3


28 CD3G CD3g molecule 917 0 4.6 4.5
 2.0
 3.4
 5.2
 5.8
 8.4
 3.2
29 RAC2 Rac family small GTPase 2 5880 0 4.6 4.7
 2.9
 3.8
 3.6
0.5
 4.0
0.2
 3.3
0.1
 4.4
0.9
 5.4
0.9
30 ITGAL integrin subunit alpha L 3683 3 4.6 4.4
 2.1
 3.2
 2.3
 3.7
 3.3
 3.2
31 ARHGAP15 Rho GTPase activating protein 15 55843 0 4.5 5.6
 1.6
 5.3
 4.6
3.6
 5.4
4.2
 5.1
2.9
 3.1
2.9
 4.5
2.6
32 FASLG Fas ligand 356 0 4.4 3.9
 3.0
 2.4
 3.1
 4.9
2.1
33 CD48 CD48 molecule 962 0 4.4 4.1
 1.7
 2.8
 3.2
 2.6
 0.8
 3.1
 4.7
34 CST7 cystatin F 8530 0 4.4 5.2
 3.1
 4.8
 5.2
 3.3
 4.5
 1.1
 4.8
35 BCL2L15 BCL2 like 15 440603 0 4.4 4.0
 2.0
 2.6
 1.3
 6.4
2.0
36 ITGAE integrin subunit alpha E 3682 0 4.3 3.0
 0.0
 1.0
 2.5
 3.3
 1.7
 1.2
37 SNX20 sorting nexin 20 124460 0 4.2 2.8
 0.6
 0.8
 0.8
0.1
 1.3
-0.4
 2.3
0.1
 3.1
-0.5
 1.3
-0.8
38 IKZF1 IKAROS family zinc finger 1 10320 0 4.2 4.3
 1.6
 3.4
 4.4
 3.7
 3.1
 0.9
 3.2
39 RASAL3 RAS protein activator like 3 64926 0 4.2 3.6
 1.7
 2.2
 2.6
 3.3
 3.5
 1.9
 3.5
40 SPN sialophorin 6693 0 4.1 4.0
 1.3
 2.8
 2.9
 4.2
 7.5
 0.7
41 KLRC4 killer cell lectin like receptor C4 8302 0 4.1 4.6
 2.8
 4.0
 5.2
4.2
 4.3
 7.1
 1.7
1.3
 0.3
42 CRTAM cytotoxic and regulatory T cell molecule 56253 0 4.0 4.4
 3.6
 3.7
 4.3
 5.0
 2.7
4.6
43 PTCSC1 papillary thyroid carcinoma susceptibility candidate 1 100302522 0 4.0 4.0
 0.2





44 LY9 lymphocyte antigen 9 4063 0 4.0 3.9
 1.3
 2.8
 5.7
5.4
 4.1
2.5
 5.1
1.8
 3.1
2.4
45 SYTL3 synaptotagmin like 3 94120 0 4.0 4.1
 2.1
 3.1
 2.6

1.2
 3.0
46 FCRL6 Fc receptor like 6 343413 0 4.0 3.5
2.1
 3.0



47 P2RY10 P2Y receptor family member 10 27334 0 4.0 4.3
 2.3
 3.6
 5.0
 5.9
2.3
 8.5
1.6
 1.4
 5.1
-0.2
48 C11orf21 chromosome 11 open reading frame 21 29125 0 4.0 2.3
 1.8
 0.0




49 ITGA4 integrin subunit alpha 4 3676 0 3.9 4.0
 2.4
 3.2
 1.3
 2.4
 2.0
 3.0
 1.1
50 KLRC1 killer cell lectin like receptor C1 3821 0 3.9 4.5
4.0
 5.2
4.2
 4.3
 7.1
 1.7
1.3
 0.3
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