Orthologous genes in OrthoFinder**

Species Gene Description
 mmu-m.5   Pole   polymerase (DNA directed), epsilon 
 mmu-u.4   Pole   polymerase (DNA directed), epsilon 
 mmu-r.6   Pole   polymerase (DNA directed), epsilon 
 rno-u.3   Pole   DNA polymerase epsilon, catalytic subunit 
 hsa-u.4   POLE   DNA polymerase epsilon, catalytic subunit 
 mcc-u.3   POLE   DNA polymerase epsilon, catalytic subunit 
 cfa-u.3   POLE   DNA polymerase epsilon, catalytic subunit 
 gga-u.3   POLE   DNA polymerase epsilon, catalytic subunit 
 dre-u.3   pole   polymerase (DNA directed), epsilon 
 dme-u.3   DNApol-epsilon255   DNA polymerase epsilon 255kD subunit 
 cel-u.3   pole-1   DNA polymerase epsilon catalytic subunit 
 sce-u.3   POL2   DNA polymerase epsilon catalytic subunit 
 spo-u.3   alg2   putative mannosyltransferase complex subunit Alg2 

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Top 50 coexpressed genes to Pole (mmu-m.5 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 mmu3030   DNA replication  9 32 7.47
 mmu4110   Cell cycle  9 122 7.20
 mmu3440   Homologous recombination  6 37 7.14
 mmu3460   Fanconi anemia pathway  3 50 4.86
 mmu3430   Mismatch repair  3 21 4.51

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mmu:Pole (polymerase (DNA directed), epsilon) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

mmu-m.5
for
Pole
mmu-u.4
for
Pole
mmu-r.6
for
Pole
rno-u.3
for
Pole
hsa-u.4
for
POLE
mcc-u.3
for
POLE
cfa-u.3
for
POLE
gga-u.3
for
POLE
dre-u.3
for
pole
dme-u.3
for
DNApol-epsilon255
cel-u.3
for
pole-1
sce-u.3
for
POL2
spo-u.3
for
alg2
1 Mms22l MMS22-like, DNA repair protein 212377 0 6.7 12.2
 9.8
 8.8
 4.7
 4.7
 2.9
 4.3
 7.0



2 Mcm5 minichromosome maintenance complex component 5 17218 0 6.0 12.7
 11.9
 8.5
 7.9
 9.0
 6.8
 11.3
 10.0
 8.9
 8.9
 0.9
 1.2
3 Lig1 ligase I, DNA, ATP-dependent 16881 0 5.9 11.5
 9.8
 5.7
 9.0
 5.7
 3.3
 9.1
 8.5
 11.6
 6.2
 5.9
 0.1
-0.0
4 Wdhd1 WD repeat and HMG-box DNA binding protein 1 218973 0 5.7 10.2
 7.9
 9.1
 3.8
 5.4
 4.5
 4.5
 10.5
 9.3
 8.4
 5.1
5 Mcm3 minichromosome maintenance complex component 3 17215 0 5.6 12.3
 11.9
 7.4
 6.4
 7.8
 7.6
 10.5
 9.1
-0.4
 7.6
 10.6
 2.8
6 Kntc1 kinetochore associated 1 208628 0 5.5 10.0
 8.0
 8.4
 9.3
 6.1
 5.2
 5.6
 7.9
 7.1
 11.5

7 Brca2 breast cancer 2, early onset 12190 0 5.4 9.6
 7.5
 6.9
 3.1
 4.5
 4.5
 3.8
 4.1



8 Rad51 RAD51 recombinase 19361 0 5.2 10.9
 10.0
 5.8
 4.5
 5.5
 5.3
 6.0
 5.6
 1.8
 4.1
 1.0
9 Rad51ap1 RAD51 associated protein 1 19362 0 5.0 10.3
 9.3
 6.3
 3.5
 5.0
 4.7
 -1.0
 5.3



10 Mcm6 minichromosome maintenance complex component 6 17219 0 5.0 10.7
 10.1
 6.6
 5.1
 7.1
 5.4
 7.2
 9.1
-0.3
 9.0
 8.3
 2.7
 -0.6
11 Mcm2 minichromosome maintenance complex component 2 17216 0 4.9 10.6
 10.1
 6.9
 7.3
 8.2
 6.6
 9.6
 10.2
 9.1
 9.7
 2.4
12 Chaf1b chromatin assembly factor 1, subunit B (p60) 110749 0 4.8 10.3
 9.7
 5.8
 6.0
 4.9
 4.7
 4.9
 7.5
 5.9
 5.9
 3.1
 0.9
13 Cdca5 cell division cycle associated 5 67849 0 4.7 8.2
 6.2
5.0
 5.5

4.5



14 Dscc1 DNA replication and sister chromatid cohesion 1 72107 0 4.7 9.4
 8.3
 6.3
 3.5
 4.4
 3.2
 3.6
 6.6
 6.5
 6.1
 -0.9
 -0.4
15 Zwilch zwilch kinetochore protein 68014 0 4.6 10.7
 10.8
 4.1
 2.3
 3.6
 4.5
 2.0
 5.1
 1.8
 5.2

16 Mcm7 minichromosome maintenance complex component 7 17220 0 4.5 9.9
 9.5
 5.3
 7.8
 7.5
 4.8
 7.3
 6.5
 6.9
 8.5
 1.7
 -0.1
17 Cdc45 cell division cycle 45 12544 0 4.5 10.1
 10.0
 8.3
 5.2
 5.9
 7.1
 3.6
 10.5
 9.3
 4.6
 4.5
 2.3
18 Timeless timeless circadian clock 1 21853 0 4.3 8.3
 7.1
 7.2
 9.5
 5.3
 5.6
 8.2
 1.6
 8.9
 9.5

19 Gins1 GINS complex subunit 1 (Psf1 homolog) 69270 0 4.3 8.8
 8.1
 7.7
 3.4
 1.9
 2.8
 8.5
 5.6
 1.5
 3.9
 1.6
 0.7
20 Topbp1 topoisomerase (DNA) II binding protein 1 235559 0 4.2 10.1
 10.4
 5.2
 5.8
 3.7
 4.6
 4.0
 5.1
 6.0
1.0
 0.2
21 Cenpn centromere protein N 72155 0 4.2 6.9
 4.7
 3.3
 2.3
 4.6
 3.7
 3.2
 4.7



22 Pask PAS domain containing serine/threonine kinase 269224 0 4.2 9.0
 8.5
 6.0
 6.8
 3.0
 2.9
 3.1
 4.1
 -0.1
0.1
 -0.1
23 Zgrf1 zinc finger, GRF-type containing 1 71643 0 4.2

4.8
 6.4
 5.5
 3.7
 4.3




24 Clspn claspin 269582 0 4.2 8.7
 8.0
 4.5
 4.1
 6.2
 6.2
 5.9
 9.7
 9.7
 3.9

25 Ncaph non-SMC condensin I complex, subunit H 215387 0 4.2 8.0
 6.8
2.3
 4.8
 4.9
 5.6
 6.1
 1.7
2.1
26 Tonsl tonsoku-like, DNA repair protein 72749 0 4.2 8.0
 6.7
 4.2
 7.8
 5.8
 2.4
11.5
 3.0


27 Chtf18 CTF18, chromosome transmission fidelity factor 18 214901 1 4.2 9.5
 9.4
 5.8
 5.8
 3.5
 5.8
 6.3
 7.6
 8.0
 2.3
 5.3
28 Tcf19 transcription factor 19 106795 0 4.1 9.0
 8.6
 3.5
 5.2
 5.3
 3.9
4.5



29 Hells helicase, lymphoid specific 15201 0 4.1 9.1
 8.9
 4.4
 4.9
 4.1
 4.9
 4.2
 10.6

3.6
30 Pold1 polymerase (DNA directed), delta 1, catalytic subunit 18971 1 4.1 8.2
 7.3
 6.3
 8.1
 -0.2
 5.3
 6.3
 9.2
 12.0
 6.0
 6.7
 1.9
31 Kif4 kinesin family member 4 16571 0 4.0 7.6
 6.4
 4.4
 1.0
 3.7
 5.6
 3.6
 9.4
 3.1
 8.9
0.6
32 Fignl1 fidgetin-like 1 60530 0 4.0 9.4
 9.5
 3.3
 4.5
 2.3
 1.8
 5.5
 2.9
 1.6
 1.0

33 Cdc6 cell division cycle 6 23834 0 4.0 9.4
 9.5
 5.4
 4.2
 4.8
 4.6
 8.2
 5.6
 4.0
 2.7
 0.4
 1.0
34 Mcm8 minichromosome maintenance 8 homologous recombination repair factor 66634 0 4.0 8.5
 7.9
 5.0
 6.0
 4.4
 2.2
 0.5
 8.9
 3.1


35 Stil Scl/Tal1 interrupting locus 20460 0 4.0 8.5
 8.1
 6.1
 2.9
 4.7
 3.1
 3.6
 6.8



36 Mcm4 minichromosome maintenance complex component 4 17217 0 4.0 9.0
 9.0
 5.3
 6.8
 7.8
 5.8
 11.1
 8.4
 9.3
 9.3
 2.2
 0.7
37 Exo1 exonuclease 1 26909 0 3.9 9.3
 9.5
 6.9
 3.7
 5.6
 4.9
 4.8
 7.7
 6.2
 4.1
 2.2
1.6
 -2.2
38 Cenpi centromere protein I 102920 0 3.9 7.2
 5.8
 5.2
 2.2
 3.7
 4.7
 3.9
 4.2



39 Espl1 extra spindle pole bodies 1, separase 105988 0 3.9 7.3
 6.1
 5.2
 6.1
 3.6
 5.0
 7.4
 5.6
 4.7
 7.1
1.2
 4.1
 0.8
40 Rad54l RAD54 like (S. cerevisiae) 19366 0 3.9 8.4
 8.0
 7.2
 6.0
 6.0
 4.6
 6.8
 5.4
 3.9
 2.6
 1.8
 0.3
41 Ncapd2 non-SMC condensin I complex, subunit D2 68298 0 3.9 7.9
 7.1
 5.8
 4.8
 7.2
 5.5
 7.5
 7.3
 6.9
 4.2
 4.6
 0.4
42 Prim1 DNA primase, p49 subunit 19075 0 3.8 8.4
 8.1
 3.5
 4.7
 3.4
 4.0
 4.5
 7.2
 7.0
 5.7
-0.8
 1.1
 0.5
43 Asf1b anti-silencing function 1B histone chaperone 66929 0 3.8 7.8
 7.1
 6.0
-0.1
 4.4
-1.7
 2.0
-0.9
 5.6
0.5
 -0.2
-0.8
 8.3
5.2
 4.5
 3.5
0.5
 3.6
 0.5
44 E2f7 E2F transcription factor 7 52679 0 3.8 7.7
 7.0
 3.7
 2.8
 6.3
 3.2
 3.4
 3.6
0.6

45 Brca1 breast cancer 1, early onset 12189 0 3.8 8.5
 8.4
 9.2
 3.7
 4.9
 4.2
 6.5




46 Atad5 ATPase family, AAA domain containing 5 237877 0 3.7 7.5
 6.6
 6.1
 5.0
 4.4
 4.0
 3.8
 9.8
4.1
 6.5
3.9
47 Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 18140 0 3.7 9.7
 10.5
 5.1
 4.6
 6.6
 4.8
 5.7
 9.3



48 Cdt1 chromatin licensing and DNA replication factor 1 67177 0 3.7 7.2
 6.1
 6.0
 4.3
 5.1
 3.9
 9.7
 3.5
 6.8
 4.7

49 Gins2 GINS complex subunit 2 (Psf2 homolog) 272551 0 3.7 8.2
 7.9
 4.0
 4.5
 6.1
 2.1
 7.0
 8.7
 0.0
 3.3
 -0.1
50 Top2a topoisomerase (DNA) II alpha 21973 0 3.7 7.5
 6.8
 3.9
-0.5
 0.4
0.1
 4.6
0.0
 4.7
0.3
 5.3
0.5
 9.7
2.0
 3.8
 9.9
3.7
 6.4
 1.0
0.8
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