Publication for CD3D and CD3G

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
hsa	CD3D	CD3d molecule	915			[link]
hsa	CD3G	CD3g molecule	917

Pubmed ID	Priority	Text
22262845	0.98	CD3gamma and CD3delta with either of the CD3epsilon domains in the CD3epsilon homodimer, because the heterodimeric interfaces are distinct from the homodimeric interface (Fig. 2A).
	0.98	CD3delta and approximately half those of CD3gamma failed to reach the surface of Jluchi cells (supplemental Fig. S6, A and B).
	0.97	CD3gamma and with CD3delta?
	0.97	CD3gamma or CD3delta (circled in Fig. 2A).
	0.97	CD3gamma or CD3delta creates a clash (circled) that prevents the formation of the small homodimerization interface involving the C-terminal loops of CD3epsilon (box (ii) in Fig. 1B).
	0.97	CD3gamma and delta contact the TCRalphabeta heterodimer or whether one (most likely CD3delta) forms the major contact and stabilizes the association of the other in the complex in the absence of direct contacts with TCRalphabeta.
	0.97	CD3delta, and presumably CD3gamma, to mutation was likely due to folding effects, we established a CD3delta folding assay based on the observation that in 293T cells, CD3epsilon surface expression requires only CD3delta co-expression (supplemental Fig. S6E; CD3gamma does not rescue CD3epsilon expression).
	0.96	CD3delta and CD3gamma.
	0.96	CD3delta and CD3gamma according to NACCESS (apart from those buried by CD3epsilon) were mutated and tested for expression in Jluchi cells.
	0.96	CD3gamma and CD3delta could form small contacts with TCRalphabeta.
	0.95	CD3delta, and CD3epsilon; (ii) TCRbeta, CD3gamma, and CD3epsilon; and (iii) TCRalpha and the two copies of CD3zeta.
	0.95	CD3delta and CD3gamma, CD3epsilon is completely exposed in the TCR complex.
	0.95	CD3delta and CD3gamma, CD3epsilon is apparently completely exposed in the complex.
	0.95	CD3delta and CD3gamma but is inconsistent with early and more recent studies.
	0.95	CD3delta and gamma, where all four of the conserved glycosylation sites are found in primates (at the start of the C and G strands in CD3gamma and in the BC and FG loops of CD3delta), are exposed in the complex.
	0.94	CD3delta and CD3gamma into the TCR complex was less efficient than for CD3epsilon, and only the most highly transfected cells could be analyzed.
	0.93	CD3delta (blue) and CD3gamma (green) each docked with one of the CD3epsilon monomers in the CD3epsilon homodimer (red and yellow), in the manner observed in the NMR structures of the CD3epsilondelta and CD3epsilongamma heterodimers.
	0.85	CD3delta and CD3gamma chains directly, because CD3epsilon is present in both heterodimers.
	0.84	CD3gamma and CD3delta only.
	0.81	CD3delta (blue; Protein Data Bank code 1XMW) and CD3gamma (green; Protein Data Bank code 1JBJ) shown docked with the red CD3epsilon monomer in the positions that CD3delta and CD3gamma occupy in the NMR structures of the CD3epsilondelta and CD3epsilongamma heterodimers.
	0.68	CD3delta mutants that failed to reach the surface of Jluchi cells (Leu8 and Lys61) and one that reduced expression (Lys41) rescued CD3epsilon expression in 293T cells (supplemental Fig. S6, F and G), indicating that CD3delta folding, and presumably also CD3gamma folding, is extremely sensitive to mutation.
	0.65	CD3gamma and CD3delta, formation of a CD3gamma-CD3delta-(CD3epsilon)2 heterotetramer via CD3epsilon homodimerization would nevertheless be precluded by steric clashes between the AB loops of CD3gamma and CD3delta and between the EF loop of each CD3epsilon monomer and the EF loop of the CD3gamma and CD3delta subunit bound to the other CD3epsilon monomer (Fig. 2B).
	0.50	CD3delta and CD3gamma.
20660709	0.98	CD3gamma, CD3delta, and CD3epsilon genes arose from a common ancestor in a two-step process of gene duplication.
	0.98	CD3gamma and CD3delta.
	0.98	CD3gamma and CD3delta are shown as stick models.
	0.98	CD3gamma and CD3delta from mouse, human, and sheep.
	0.97	CD3gamma G-strand into CD3delta creates an mCD3epsilongamma chimera reactive with 17A2.
	0.96	CD3gamma-/- mice using the hCD3delta (human only) construct.
	0.96	CD3gamma and CD3delta subunit evolved with highly homologous heterodimeric interfaces and membrane proximal segments for efficient and specific signaling transfer when paired with CD3epsilon.
	0.95	CD3gamma and CD3delta ectodomains shows that there is differential G-strand geometry resulting in a pronounced cleft between the two CD3 ectodomains in CD3epsilongamma that is partially occluded in CD3epsilondelta (Fig. 1A).
	0.93	CD3gamma and CD3delta are recognized by the 17A2 anti-mCD3epsilongamma mAb
	0.93	CD3gamma ectodomain are denoted in the accompanying ribbon diagrams (CD3epsilon, cyan; CD3gamma, green; and CD3delta, yellow).
	0.91	CD3gamma or CD3delta sequences are shown in green or yellow background, respectively.
	0.88	CD3gamma, the CD3delta BC loop is five residues shorter, containing only four amino acids (Fig. 1B).
	0.72	CD3gamma and CD3delta G-strand geometries impacting ectodomain shape.
	0.68	CD3delta subunit ectodomain would sterically clash with the Cbeta FG loop above, whereas that of CD3gamma or the chimeric heterodimer does not.
	0.64	CD3gamma and CD3delta orthologs are shown in red background.
	0.52	CD3gamma and CD3delta ectodomains within these heterodimers are more divergent from one another.
	0.50	hCD3delta ectodomain to pair with mCD3epsilon and foster TCR complex expression signaling, as well as murine thymocyte development, might appear, at first glance, contradictory to our view that CD3gamma and CD3delta ectodomains evolved to occupy a different side of the TCR complex.
17822534	0.98	CD3gamma transcripts decrease is followed by a subsequent progressive and sequential reduction in CD3delta, CD3epsilon and CD3zeta genes transcription, going on after early viral genes silencing.
	0.98	CD3gamma and CD3delta could be restored in CD3epsilon-/- mice by deletion of the neomycin cassette using in vivo recombination but not by transgenic reconstitution of CD3epsilon protein expression.
	0.98	CD3gamma and CD3delta gene expression p.i.
	0.97	CD3gamma and CD3delta genes transcription.
	0.96	CD3gamma, CD3delta and GAPDH (endogenous control) RT-PCR products from untreated HTLV-I infected CD3gamma-deltalo, TSA/AZA HTLV-I infected CD3gamma-deltalo (treated for 72 hours with 4 muM of 5'AZA and for 18 hours with 500 nM of TSA) and uninfected untreated WE17/10 cells.
	0.95	CD3gamma or CD3delta genes had no effect on transcription of their other two neighboring CD3 genes.
	0.95	CD3gamma core promoter and rescued the transcription of CD3gamma and CD3delta in the CD3- HTLV-I infected.
	0.91	CD3gamma and CD3delta promoters and the CD3delta enhancer.
	0.89	CD3gamma, 48% CD3delta, 62% CD3epsilon and 75% CD3zeta gene transcripts.
	0.68	CD3gamma, CD3delta, CD3epsilon, and CD3zeta gene transcripts leading to a CD3- surface phenotype after 200 days of in vitro infection; however, the sequence of gene loss has not been investigated.
	0.66	CD3delta as well as CD3gamma transcripts.
15728236	0.98	CD3gamma and CD3delta endocytotic signals are inactive.
	0.97	CD3gamma or CD3delta.
	0.95	CD3gamma, CD3e, CD3delta, and CD3zeta (the CD3zeta subunit is CD247).
	0.92	CD3gamma, CD3delta, TCRalpha, and TCRbeta become progressively inoperative as they assemble with CD3e.
	0.86	CD3gamma, CD3delta, and CD3e chains (Fig. 5 B).
	0.85	CD3gamma has a conserved arginine residue in position -3 from the COOH terminus, and CD3delta has either an arginine or a lysine residue at the same position.
	0.78	CD3delta, and CD3gamma (15, 20-22, and this study), and it could be considered that all ER retention signals are abrogated simultaneously when the full TCR complex is assembled.
	0.76	CD3gamma or CD3delta, and the resulting egamma and edelta dimers associate with the TCRalpha and TCRbeta subunits.
	0.76	CD3gamma and CD3delta are overridden, but surface expression of the egamma and edelta dimers is prevented by the CD3e ER retention signal that remains functional.
	0.63	CD3delta may contain at least one cytoplasmic ER retention signal similar to those of CD3gamma and CD3e (triangle) and a di-leucine endocytosis signal (circle).
23336327	0.98	CD3G (gamma+/-) or CD3D (delta+/-, delta+/leaky) with that of normal controls.
	0.95	CD3gamma, but not of the homologous CD3delta chain.
	0.92	CD3gamma+/- but not CD3delta+/- or CD3delta+/leaky human T lymphocytes
	0.90	CD3gamma, but not of the homologous CD3delta chain.
	0.85	CD3gamma, but not CD3delta, than that of the alphabeta TCR.
	0.83	CD3G and CD3D genotypes, relative to normal controls, revealed that binding of CD3 mAb to gamma+/- gammadelta T cells was unexpectedly poor (55 +- 3%) as compared with gamma+/- alphabeta T cells (82 +- 8%, Figure 2A).
	0.80	CD3gamma, but not CD3delta, haploinsufficiency differentially impairs gammadelta versus alphabeta surface TCR expression
	0.79	CD3G or CD3D mutations showed affected TCR expression (Figure 2) and T-cell selection (Figure 1), which seemed in turn to impair to some extent T-cell function (Table 1) the question of whether they also have increased risk of immunological dysfunction deserves further investigation.
9236191	0.98	CD3-gamma or CD3-delta were coexpressed.
	0.97	CD3-gamma and most likely also with CD3-delta, two subunits competing for binding to CD3-epsilon at an early stage of TCR assembly.
	0.92	CD3-gamma for its interaction with CD3-epsilon are also conserved in the primary structure of CD3delta, which suggests that both CD3-gamma and -delta share a common binding motif in CD3-epsilon.
	0.92	CD3-gamma and/or CD3-delta subunits are available.
21078154	0.98	CD3delta, CD3epsilon, CD3zeta or CD3gamma defect can cause AR T-B+NK+ SCID (about 1% of SCID): the different CD3 subunits, organized as gammaepsilon, deltaepsilon and zetazeta dimers, join to pre-TCR and then TCR and are essential for their assemblage in cell membrane and signal transmission and therefore thymic T lymphopoiesis and mature T lymphocyte activation; defects cause differently severe phenotypes.
	0.96	CD3delta, CD3epsilon, CD3zeta or CD3gamma defect (OMIM 608971; 608971; 610163; 186830)
	0.78	CD3gamma, CD3delta, CD3epsilon, CD3zeta), protein-tyrosine kinases (e.g., Fyn, Lck, ZAP-70), protein-phosphotyrosine phosphatases (CD45, and others), etc.
30863395	0.98	CD3D, CD3E, CD3G, and TRBC1/2 (Figure 5B).
	0.97	CD3D, CD3G, and TRBC1/2 within the 20 best hits (p < 0.05, sorted on protein enrichment, Figure 5D).
	0.96	CD3D, CD3G, TRBC1/2 were overlapping.
24244363	0.98	CD3G gene, while CD247 and CD3EAP genes had the least number and there were no conserved miRNA associated with the CD3D gene.
	0.97	CD3-Gamma, CD3-Delta, CD3-Epsilon and CD3-zeta.
32020855	0.98	CD3G), T-cell surface glycoprotein CD3 delta chain(CD3D), B-cell antigen receptor complex-associated protein beta chain(CD79B), B-cell antigen receptor complex-associated protein alpha chain(CD79A).
	0.90	CD3G, CD3D are the components of TCR/CD3 complex which are expressed on the cell surface to mediates signal transduction.
17923503	0.97	hCD3gamma (HMT3.2), hCD3delta (APA1/2), zeta (G3), and hTCRgammadelta (5A6.E9), separated by BN-PAGE and analyzed as in A. The number of shifts correlates with the number of antibody binding sites in the TCR complex, as indicated by arrowheads.
	0.92	CD3gamma and CD3delta immunodeficiencies
	0.82	CD3gamma and anti-CD3delta antibodies, we expressed individual mouse and human TCR subunits in Drosophila S2 cells and performed subsequent immunopurifications, verifying antibody specificity for HMT3.2 (anti-hCD3gamma) and APA1/2 (anti-hCD3delta; Fig. S2 A, available at http://www.jem.org/cgi/content/full/jem.20070782/DC1).
	0.76	CD3gamma-deficient gammadelta TCRs are still able to support gammadelta T cell development in humans (Fig. 1), likely because hCD3delta can partially substitute for hCD3gamma.
	0.67	CD3delta transgene rescues gammadelta T cell development in mice lacking both mouse CD3delta and CD3gamma chains.
	0.66	CD3delta had similar mobility to CD3gamma and, therefore, could not be resolved when biotinylated proteins were detected by SDS-PAGE and streptavidin Western blotting.
26388869	0.97	CD3gamma, and CD3delta subunit has been previously determined to be crucial for thymocyte development and T cell activation.
	0.97	CD3gamma and CD3delta genes are unique in the mammalian species among gnathostamata (Figure 3).
	0.96	CD3gamma and CD3delta subunits in the above-mentioned non-mammalian species and expression of a single precursor CD3gammadelta gene (CD3p) have been shown based on the genomic and biochemical analyses as well as theoretical predictions dating the required CD3 duplication event.
	0.95	CD3gamma and CD3delta genes are present relative to the TCR genes found in birds, amphibians, reptiles, and bony fish.
	0.70	CD3gamma can be classified to the C2-set, CD3delta adopts the C1-set fold.
11390434	0.97	CD3delta/epsilon and CD3 gamma/epsilon heterodimers), respectively.
	0.96	CD3delta Ab that was used in these experiments had a somewhat weaker reactivity compared with the CD3gamma Ab, we did not observe coprecipitation of CD3delta with TRIM in several experiments and even after prolonged overexposure of the autoradiograph.
	0.92	CD3gamma, CD3delta, or CD3epsilon, or a mAb directed at zeta.
29977931	0.97	CD3D, CD3E, and CD3G, which are compositions of CD3 complex of TCR, interacted with each other to affect the assembly of TCR membrane complex and disturb T-cell responsiveness, especially CD3E.
	0.69	CD3G, B2M, interferon-gamma, CD3D, tumor necrosis factor, VAV1, and CD3E in the T cell receptor signaling pathway were selected as important factors, and LCK was identified as the hub protein.
	0.58	CD3G, B2M, IFNG, CD3D, TNF, VAV1, and CD3E in previous studies.
9500786	0.97	CD3-delta and CD3-gamma each dimerize with CD3-epsilon through their luminal domains.
	0.92	CD3-delta are particularly susceptible to degradation from the ER, whereas CD3-gamma and CD3-epsilon generally exhibit considerably longer half-lives.
2139038	0.97	CD3 delta were degraded rapidly, whereas CD3 gamma and epsilon were stable.
25409740	0.97	CD3G-CD3E-CD3D) were strongly increased after birth in the ovine fetal hippocampus, when measured by RT-PCR (Additional file 9: Figure S7), rising the possibility that T cells are present in the fetal brain.
22401598	0.96	CD3gamma expression level decreased from 34.03 to 1.31, the CD3delta expression level decreased from 3.36 to 0.52, the CD3epsilon expression level decreased from 45.06 to 2.96, the CD3zeta expression level decreased from 10.96 to 0.86, and the FcepsilonRIgamma expression level increased from 5.97 to 107.55 in the 3 months after treatment in 1 case (Figure 2A).
	0.94	CD3gamma (17.84 +- 20.97, p = 0.015), CD3delta (3.24 +- 2.61, p = 0.002), CD3epsilon (15.73 +- 11.44, p = 0.000), and CD3zeta (5.65 +- 3.51, p = 0.000) were observed in patients with AA compared to the healthy controls (CD3gamma (4.43 +- 2.67), CD3delta (1.02 +- 0.69), CD3epsilon (3.36 +- 2.09), and CD3zeta (1.83 +- 1.21) for the healthy controls; Figure 1).
	0.93	CD3gamma, CD3delta, CD3epsilon and CD3zeta genes in patients with AA were significantly increased compared to a healthy control group, whereas the FcepsilonRIgamma gene expression level was significantly decreased in patients with AA in comparison with the healthy control group.
	0.90	CD3gamma, CD3delta, CD3epsilon, CD3zeta and FcepsilonRIgamma gene expression levels in 2 patients with AA who were in remission.
	0.86	CD3gamma expression level decreased from 10.57 to 0.82, the CD3delta expression level decreased from 3.95 to 0.63, the CD3epsilon expression level decreased from 19.14 to 2.23, the CD3zeta expression level decreased from 5.91 to 0.54, and the FcepsilonRIgamma expression level increased from 30.89 to 36.60 in the 4 months after treatment (Figure 2B).
	0.54	CD3gamma, CD3delta, CD3epsilon, CD3zeta and FcepsilonRIgamma in cDNA obtained from the PBMCs of 18 patients with AA before treatment and 14 healthy individuals were quantitatively assessed by real-time PCR using the SYBR Green I method.
23046125	0.96	CD3delta subunits significantly shorter compared to that of CD3epsilon and CD3gamma subunits.
	0.95	CD3gamma plus CD3delta genes from a single precursor (CD3P) in Gnathostamata
	0.94	CD3gamma and CD3delta subunits do not exist in non-mammalian species such as birds, amphibians, reptiles, and bony fish.
	0.93	CD3gamma and CD3delta genes and their products, as shown in Fig. 7.
	0.85	CD3gamma G-strand is crucial for maximizing pMHC-triggered T cell activation and TCR surface expression, offering a geometry to accommodate the juxtaposition of CD3gamma and TCRbeta ectodomains and to foster quaternary change that cannot be replaced by the isologous CD3delta subunits extracellular region.
	0.84	CD3gamma and CD3delta) each comprise a single extracellular Ig-like domain followed by a short stalk region, referred to as a connecting peptide (CP), a transmembrane (TM) helix, and a cytoplasmic tail.
11342589	0.96	CD3gamma, CD3delta, and CD3epsilon subunits.
	0.95	CD3gamma chains, and deglycosyl-ated CD3gamma (dgamma) and CD3delta (ddelta) are indicated on the right.
25688246	0.96	CD3gamma/CD3epsilon, and CD3delta/CD3epsilon) and a single CD247 homodimer (also termed zeta/zeta).
29703840	0.95	CD3d and Cd3g mRNA in Ctrl (red) and RId2-/- (blue) CD27+CD11b- BM NK cells is shown relative to Hprt mRNA.
	0.95	Cd3d and CD3g are shown with black arrows indicating regions of increased accessibility in RId2-/- as compared to Ctrl.
	0.91	Cd3g and Cd3d mRNA by qRT-PCR (Fig. 4C) and CXCR5, CXCR3, IL-4Ralpha, and CD27 on RId2-/- CD27+CD11b- NK cells by flow cytometry (Fig. 4D).
	0.82	CD3g and Cd3d and identified regions that increased accessibility in RId2-/- as compared to Ctrl CD27+CD11b- cells and decreased accessibility upon NK cell differentiation (Fig. 6A, B).
24464682	0.95	CD3gamma, CD3delta and CD3epsilon chains, each of which contain a single extracellular Ig domain, are closely related.
	0.78	CD3gamma and CD3delta molecules were derived from a tandem gene duplication.
	0.70	CD3gamma and CD3delta subunits are replaced by a CD3gamma/delta subunit .
27183595	0.95	CD3delta than to CD3gamma and closer to the JM region of the CD3 heterodimers than to CD3zetazeta.
	0.75	CD3delta than CD3gamma and closer to the CD3epsilon subunits than the CD3zetazeta subunits.
	0.66	CD3delta and CD3gamma.
23885256	0.95	CD3gamma and CD3delta contact the TCR, whereas CD3epsilon projects away from the receptor.
	0.65	CD3gamma or CD3delta, may confer preference to CD3epsilon in the ITAM phosphorylation cascade upon Lck recruitment by CD4 (Figure 4A).
25946140	0.95	CD3D, CD3E, and CD3G genes for T-cell receptor signaling components.
	0.66	CD3G and CD3D.
21264308	0.95	CD3gamma and CD3delta mRNA, these lanes were used as a control in order to exclude a contamination by ordinary T cells.
22737151	0.94	CD3delta and CD3gamma fused to EPOR.
	0.82	CD3delta and CD3gamma, associate with the acidic inner leaf of the membrane (Aivazian and Stern,; Sigalov et al.,; Kuhns and Davis,; Xu et al.,; Deford-Watts et al.,; DeFord-Watts et al.,; Zhang et al.,).
	0.71	CD3gamma and CD3delta intracellular domains would emerge from the membrane to flank the CD3epsilon intracellular domains on one side of the TCR.
	0.61	CD3gamma or CD3delta, contain stretches of basic residues that are thought to facilitate interactions with the acidic inner leaf of the membrane.
29967623	0.94	CD3G, CD3Z, CD3D, LCK, CD3E, NFAT, ZAP70, GADS, FYN, ITK, P38, and IFNgamma) were mapped to T cell receptor signaling KEGG pathway (Figure 6A).
	0.86	CD3D, CD3E, CD3G, and CD3Z were the first neighbors of IFNgamma (Additional File 9: Figure S1C in Supplementary Material).
	0.79	CD3D/NFATC2/CD3E/LCK/CD3G panel, and FASLG/CD8A/PRF1/granzyme B panel.
	0.67	CD3D, CD3E, CD3G, CD2, and CD7 genes were the first neighbors of CD8A.
22566957	0.94	CD3delta-TCRalpha-CD3zeta-CD3zeta component lie closer to the TCR alpha subunit and the three helices of the CD3epsilon-CD3gamma-TCRbeta component lie closer to the TCRbeta subunit (Call et al.,).
	0.79	CD3delta and CD3gamma subunits.
	0.52	CD3gamma, and CD3delta.
23189081	0.94	CD3gamma, CD3delta, and the two CD3epsilon chains (shades of blue) around the outside.
	0.93	CD3gamma, and CD3delta have each a single extracellular Ig domain while CD3zeta has essentially no extracellular domain.
	0.85	CD3delta and CD3gamma genes (Kim et al.,).
24426833	0.94	CD3G, CD3D, CD8A, and CD28 expression) type 1 cytotoxic immunity (increases with FASLG, IFNG, GZMB, TBX21, IL12RB2, EOMES, PRF1, B2M and decreases with GATA3 expression) and PC2 captured a correlation between WISP1 and the T cell lineage-defining transcription factors GATA3 and PPARG.
	0.75	CD3G, CD3D, CD3E), and macrophages (CD14, CPM, MRC1, ITGAM) in the breast cancer GEMM data set.
9120393	0.93	CD3-gamma, CD3-delta, and CD3-epsilon, pTalpha, and RAG-1 transcripts, and has partially rearranged the TCR-beta locus strongly suggested that committed T cell precursors were present.
	0.92	CD3-gamma, CD3-epsilon, and CD3-delta transcripts are expressed in pTalpha+ cells.
	0.65	CD3-delta, CD3-gamma, and CD3-epsilon genes.
9547330	0.93	CD3-gamma, CD3-delta, and CD3-epsilon each contain one ITAM, whereas CD3-zeta contains three.
	0.79	CD3-delta and CD3-gamma subunits, their identity could not be confirmed by probing with specific antibodies, due to technical difficulties.
	0.63	CD3-gamma, CD3-delta, CD3-epsilon, CD3-zeta) are responsible for signal transduction.
25326331	0.92	CD3G (CD3-gamma) expression is significantly correlated with CD3D (CD3-delta) expression in CD4+ T cells (r value = 0.670593, P value = 0; PP rate = 98.7%) (Figure 2A).
9230070	0.91	CD3gamma and CD3delta L-based motifs from different species (Table I).
	0.85	CD3delta subunits works as a receptor sorting motif in chimeric receptors (the present study and reference), it is not preceded by a serine and it cannot substitute for the CD3gamma motif in the context of the complete TCR.
31064990	0.91	CD3gamma, CD3delta, and CD3epsilon subunits of the TCR can be recombinantly fused using a linker sequence to an antigen-binding scFv or single-domain antibody, thereby providing the TCR and the engineered T cell with a new target specificity and the potential for HLA-independent target cell lysis.
	0.89	CD3gamma, CD3delta, or CD3epsilon.
20478055	0.90	CD3D, CD3G, IL10RA, THY1 and IL18.
28537889	0.86	CD3G and CD3D, we analyzed seven TIL markers (CD3D, CD3E, CD3G, CD4, CD8, CD20 and CD163).
20298603	0.85	CD3gamma and CD3delta it can be concluded that the TRIM-containing alphabetaTCR has a stoichiometry of TCRalphabeta CD3epsilon2gammadeltazeta2TRIM2 (Figure 2C).
	0.54	CD3gamma and CD3delta, but not in zeta, CD3epsilon or TRIM, does not target for degradation.
32158593	0.85	CD3gamma chain than CD3delta chain as human patient lacking CD3gamma have abundant peripheral blood gammadelta T cells expressing high levels of gammadelta TCR.
	0.76	CD3delta transgene rescue the gammadelta T cell development in mice deficient in both CD3delta and CD3gamma genes, suggesting the unique role of human CD3delta in the TCR signaling.
29721379	0.84	CD3D and CD3G genes, respectively, with CD3 histology density by multiplex IHC revealed correlation coefficients (r2 values) of 0.049 and 0.324 (Table 3).
21910250	0.80	CD3D, CD3G, ICOS and UBASH3A) appeared highly methylated in ex vivo B lymphocytes and not in T lymphocytes samples (Fig 6C), again indicating that the observed lymphocyte infiltration mostly involves T lymphocytes, as suggested in Fig 6A.
	0.69	CD3D, CD3G, CD6, LCK, LAX1, SIT1, RHOH, UBASH3A and ICOS; Fig 6A).
18320063	0.66	CD3gamma and CD3delta, TCRalpha forms disulfide-linked dimers with TCRbeta, and CD3zeta is expressed in the form of disulfide-linked homodimers.
23932713	0.63	CD3gamma and epsilon or CD3delta and epsilon form soon after their biosynthesis.
26215705	0.56	CD3G, and CD3D were markedly decreased, as well as antigen-presentation genes like HLA-DMA, HLA-DOA, HLA-DRA, HLA-DQA1, CIITA, HLA-DRB1, HLA-DOB, HLA-DMB, CD74, HLA-DPB1, TAP2, and HLA-DPA1.
28891951	0.51	CD3D, CD3E and CD3G) or NK cells (FCGR3A) was extracted from the TCGA database for the HNSC (A) and CESC (B) cohorts for HPV+, HPV-, and normal control tissues.
31921117	0.51	CD3delta/epsilon, CD3gamma/epsilon, and CD3zeta/zeta), which comprise the CD3 complex.