Publication for CD3D and IL2RG
| Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
|---|---|---|---|---|---|---|
| hsa | CD3D | CD3d molecule | 915 | [link] | ||
| hsa | IL2RG | interleukin 2 receptor subunit gamma | 3561 |
| Pubmed ID | Priority | Text |
|---|---|---|
| 30483789 | 0.98 | CD3D, IL2RG, IL7R, LCK and STAT1) were included in the PPI network. |
| 0.98 | CD3D (8.65), CXCR4 (10.86), IL2RG (9.27), IL7R (8.11), LCK (6.58) and STAT1 (7.36) were determined (Fig. 3A-F and Table II). | |
| 0.95 | CD3D, IL2RG, IL7R, LCK and STAT1 interacted with the primary immunodeficiency pathway, either directly or indirectly (P<0.001), which suggested that upregulated genes may activate the primary immunodeficiency pathway and increase the risk of RA development. | |
| 0.94 | CD3D, IL2RG, IL7R, LCK and STAT1) were included and notably, these genes were demonstrated to interact with the primary immunodeficiency pathway either directly (CD3D, IL2RG, IL7R and LCK) or indirectly (STAT1). | |
| 0.90 | IL2RG and CD3D may represent potential biomarkers associated with immunodeficiency in RA. | |
| 0.86 | CD3D (0.8357), CXCR4 (0.7855), IL2RG (0.8368), IL7R (0.9161), LCK (0.8683) and STAT1 (0.9138; all P<0.0001). | |
| 0.84 | IL2RG) and CD3d molecule (CD3D), and at its core was primarily associated with immunodeficiency (Fig. 2A; bottom circle). | |
| 0.84 | CD3D, IL2RG, IL7R, LCK and STAT1 may activate the primary immunodeficiency pathway and subsequently lead to primary immune system dysfunction and the development of RA. | |
| 0.83 | CD3D, (B) CXCR4, (C) IL2RG, (D) IL7R, (E) LCK and (F) STAT1 are presented. | |
| 0.81 | CD3D, CXCR4, IL2RG, IL7R, LCK and STAT1) was identified and presented in Fig. 2B, which suggested that these six genes may represent important biomarkers associated with RA and OA development and diagnosis. | |
| 0.61 | CD3D, T-cell surface glycoprotein CD3 delta chain; CXCR4, C-X-C motif chemokine receptor 4; IL2RG, interleukin 2 receptor gamma; IL7R, interleukin 7 receptor; LCK, LCK proto-oncogene, Src family tyrosine kinase; STAT1, signal transducer and activator of transcription 1. | |
| 29137350 | 0.98 | IL2RG and lymphocyte markers PTPRC and CD3D transcript levels in normal pancreatic duct and PanIN samples. |
| 31031743 | 0.97 | CD3D, JAK3, ARPC1B, MYD88/CARD9, and JAGN1, 7 hemizygous variants in IL2RG, CD40LG, and XIAP, and only 1 heterozygous somatic variant in NRAS (Figure 4C). |
| 0.89 | IL2RG, JAK3, ADA, CD3D, IL7R, CD40L, and XIAP genes (see Table 2B). | |
| 30072278 | 0.96 | CD3D, CD3E, CD2, IL2RG, NKG7, HLA-E, CIITA, HLA-DRA, LAG3, IDO1, CXCL13, TAGAP, CXCL10, and STAT1. |
| 32009323 | 0.96 | CD3delta, CD3epsilon, or CD3zeta although IL2RG and JAK3 mutations have also been shown to cause this phenotype. |
| 32185135 | 0.95 | CD3D, CCL5, CD3D, CD3E, IL2RG, CIITA, GZMK, CXCL9, CXCR6, TAGAP, CD2, HLA-E, IDO1, LAG3, NKG7, GZMB, STAT1, and CXCL10. |
| 25940795 | 0.94 | CD3D, CD3E, CD8A, CD247, KLRK1), T-cells differentiation (e.g. CD27, EOMES, STAT1, STAT4), T-cells activation (e.g. ITK, JAK3, LCK, ZAP70), cytotoxic effector molecules (e.g. GZMA/B/H/K, C1QA/B, GNLY, PRF1), inflammation/anti-tumor cytokines (e.g. IL2RA, IL2RB, IL2RG, IL12RB1, IL12RB2, IL15, IL15RA, IL18BP, IL18, IL21R, IL27RA, interferon gamma (IFNG) and its receptor, as well as many interferon-induced proteins, TNF, LTB), and chemokines related to T-cells activation and homing (e.g. CCL2/4/5/8/18, CXCL1, CXCL9/10/11, chemokine (C-C or C-X-C motifs) receptors). |
| 30585265 | 0.90 | CD3D, CXCL13 and IL2RG), we suspected the risk score may have reflected the immune cell infiltration. |
| 0.67 | CD3D) + (-0.2262*RAB36) + (-0.1740*GADD45G) + (-0.1017*CXCL13) + (-0.1197*TSPAN13) + (-0.1933*CXCL9) + (-0.0706*IL2RG), where gene name refers to the pre-processed relative expression value of corresponding gene (Fig. S1c). | |
| 29977931 | 0.90 | CD3D, IFNG, VAV1, TNF, B2M, CXCR3, CCR5, CCL5, CXCL9, CXCL10, CXCR4, GNG2, IL1B, IL12B, IL2RB, IL2RA, IL2RG, STAT1, CD8A, CD86, PTPRC, PIK2CG, CD44, and HLA-DPA1 and 1 downregulated protein EGF. |
| 32000799 | 0.90 | CD3D, CD3E, IL2RG, LAG3-2, CD24, CD79A, CD5, CD69 and related to leukocyte extravasation signaling pathway, such as the integrins ITGB7 and ITGA4:were exclusively regulated in CD-MAT (Figs. 1b, d and 2a). |
| 32218835 | 0.89 | CD3D, CD3E and NKG7), activation and function (CD2, IL2RG, TAGAP, GZMB, GZMK and STAT1), antigen presentation (CIITA, HLA-DRA, and HLA-E), chemokines and a chemokine receptor (CCL5, CCL10, CXCL13, and CXCR6) and immune checkpoint molecules (IDO1 and LAG3). |
| 30621359 | 0.87 | CD3D, AIM2, and IL2RG) in RA are related to the immune processes. |
| 29167668 | 0.85 | IL2RG, RAG1, ADA, IL7R, JAK3, DCLRE1C, and CD3D. |
| 24290292 | 0.77 | IL2RG (n=86), IL7R (22), ADA (14), DCLER1C (11), JAK3 (11), RAG2 (9), RAG1 (7), CD3D (2), CD3Z (1), CD45 (1), PNP (1), and heterozygous RAG1 and RAG2 (1). |
| 29713328 | 0.51 | IL2RG, JAK3, DCLRE1C, RAG1, RAG2, IL7R, ADA, CD3D, CD3E, CD3Z, DOCK2, AK2, and TTC7A. |
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