Publication for CD3D and IL2RG

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
hsa CD3D CD3d molecule 915 [link]
hsa IL2RG interleukin 2 receptor subunit gamma 3561

Pubmed ID Priority Text
30483789 0.98 CD3D, IL2RG, IL7R, LCK and STAT1) were included in the PPI network.
0.98 CD3D (8.65), CXCR4 (10.86), IL2RG (9.27), IL7R (8.11), LCK (6.58) and STAT1 (7.36) were determined (Fig. 3A-F and Table II).
0.95 CD3D, IL2RG, IL7R, LCK and STAT1 interacted with the primary immunodeficiency pathway, either directly or indirectly (P<0.001), which suggested that upregulated genes may activate the primary immunodeficiency pathway and increase the risk of RA development.
0.94 CD3D, IL2RG, IL7R, LCK and STAT1) were included and notably, these genes were demonstrated to interact with the primary immunodeficiency pathway either directly (CD3D, IL2RG, IL7R and LCK) or indirectly (STAT1).
0.90 IL2RG and CD3D may represent potential biomarkers associated with immunodeficiency in RA.
0.86 CD3D (0.8357), CXCR4 (0.7855), IL2RG (0.8368), IL7R (0.9161), LCK (0.8683) and STAT1 (0.9138; all P<0.0001).
0.84 IL2RG) and CD3d molecule (CD3D), and at its core was primarily associated with immunodeficiency (Fig. 2A; bottom circle).
0.84 CD3D, IL2RG, IL7R, LCK and STAT1 may activate the primary immunodeficiency pathway and subsequently lead to primary immune system dysfunction and the development of RA.
0.83 CD3D, (B) CXCR4, (C) IL2RG, (D) IL7R, (E) LCK and (F) STAT1 are presented.
0.81 CD3D, CXCR4, IL2RG, IL7R, LCK and STAT1) was identified and presented in Fig. 2B, which suggested that these six genes may represent important biomarkers associated with RA and OA development and diagnosis.
0.61 CD3D, T-cell surface glycoprotein CD3 delta chain; CXCR4, C-X-C motif chemokine receptor 4; IL2RG, interleukin 2 receptor gamma; IL7R, interleukin 7 receptor; LCK, LCK proto-oncogene, Src family tyrosine kinase; STAT1, signal transducer and activator of transcription 1.
29137350 0.98 IL2RG and lymphocyte markers PTPRC and CD3D transcript levels in normal pancreatic duct and PanIN samples.
31031743 0.97 CD3D, JAK3, ARPC1B, MYD88/CARD9, and JAGN1, 7 hemizygous variants in IL2RG, CD40LG, and XIAP, and only 1 heterozygous somatic variant in NRAS (Figure 4C).
0.89 IL2RG, JAK3, ADA, CD3D, IL7R, CD40L, and XIAP genes (see Table 2B).
30072278 0.96 CD3D, CD3E, CD2, IL2RG, NKG7, HLA-E, CIITA, HLA-DRA, LAG3, IDO1, CXCL13, TAGAP, CXCL10, and STAT1.
32009323 0.96 CD3delta, CD3epsilon, or CD3zeta although IL2RG and JAK3 mutations have also been shown to cause this phenotype.
32185135 0.95 CD3D, CCL5, CD3D, CD3E, IL2RG, CIITA, GZMK, CXCL9, CXCR6, TAGAP, CD2, HLA-E, IDO1, LAG3, NKG7, GZMB, STAT1, and CXCL10.
25940795 0.94 CD3D, CD3E, CD8A, CD247, KLRK1), T-cells differentiation (e.g. CD27, EOMES, STAT1, STAT4), T-cells activation (e.g. ITK, JAK3, LCK, ZAP70), cytotoxic effector molecules (e.g. GZMA/B/H/K, C1QA/B, GNLY, PRF1), inflammation/anti-tumor cytokines (e.g. IL2RA, IL2RB, IL2RG, IL12RB1, IL12RB2, IL15, IL15RA, IL18BP, IL18, IL21R, IL27RA, interferon gamma (IFNG) and its receptor, as well as many interferon-induced proteins, TNF, LTB), and chemokines related to T-cells activation and homing (e.g. CCL2/4/5/8/18, CXCL1, CXCL9/10/11, chemokine (C-C or C-X-C motifs) receptors).
30585265 0.90 CD3D, CXCL13 and IL2RG), we suspected the risk score may have reflected the immune cell infiltration.
0.67 CD3D) + (-0.2262*RAB36) + (-0.1740*GADD45G) + (-0.1017*CXCL13) + (-0.1197*TSPAN13) + (-0.1933*CXCL9) + (-0.0706*IL2RG), where gene name refers to the pre-processed relative expression value of corresponding gene (Fig. S1c).
29977931 0.90 CD3D, IFNG, VAV1, TNF, B2M, CXCR3, CCR5, CCL5, CXCL9, CXCL10, CXCR4, GNG2, IL1B, IL12B, IL2RB, IL2RA, IL2RG, STAT1, CD8A, CD86, PTPRC, PIK2CG, CD44, and HLA-DPA1 and 1 downregulated protein EGF.
32000799 0.90 CD3D, CD3E, IL2RG, LAG3-2, CD24, CD79A, CD5, CD69 and related to leukocyte extravasation signaling pathway, such as the integrins ITGB7 and ITGA4:were exclusively regulated in CD-MAT (Figs. 1b, d and 2a).
32218835 0.89 CD3D, CD3E and NKG7), activation and function (CD2, IL2RG, TAGAP, GZMB, GZMK and STAT1), antigen presentation (CIITA, HLA-DRA, and HLA-E), chemokines and a chemokine receptor (CCL5, CCL10, CXCL13, and CXCR6) and immune checkpoint molecules (IDO1 and LAG3).
30621359 0.87 CD3D, AIM2, and IL2RG) in RA are related to the immune processes.
29167668 0.85 IL2RG, RAG1, ADA, IL7R, JAK3, DCLRE1C, and CD3D.
24290292 0.77 IL2RG (n=86), IL7R (22), ADA (14), DCLER1C (11), JAK3 (11), RAG2 (9), RAG1 (7), CD3D (2), CD3Z (1), CD45 (1), PNP (1), and heterozygous RAG1 and RAG2 (1).
29713328 0.51 IL2RG, JAK3, DCLRE1C, RAG1, RAG2, IL7R, ADA, CD3D, CD3E, CD3Z, DOCK2, AK2, and TTC7A.



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