Publication for PRC1 and PBK

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
hsa	PRC1	protein regulator of cytokinesis 1	9055			[link]
hsa	PBK	PDZ binding kinase	55872

Pubmed ID	Priority	Text
24067424	0.98	Pbk, Cenpf, Bub1, Mki67, Cdc2, Hmmr, Ect2, Ttk, Ccna2, Prc1, Ccnb1, Bub1b, Gins1, Ns5atp9, Melk, Tyms, Aspm, Aurka, Ccne2, Bard1, E2f8, Dtl, Cep55, Kif20a, and Espl1.
30353018	0.97	PBK, PRC1, RAD51AP1, STMN1 and TOP2A (Fig. 3A).
27049917	0.96	PBK is also a mitosis kinase that it is activated by the cdk1/cyclin B1 complex to promote cytokinesis through phosphorylation of PRC1.
28677687	0.96	TOPK phosphorylates histone H3 (Ser10) during the transition from prophase to metaphase, specifically targets C2H2 zinc finger proteins to promote chromatin dissociation and complexes with cyclin B/CDK1 to phosphorylate PRC1 and promote chromosomal separation and cytokinesis.
29445374	0.95	PRC1, DLGAP5, NUSAP1, and KIF20A), transcription regulation (e.g., HIST1H1B and HIST1H3B), or lymphoid activation (e.g., PBK) were upregulated in PBMCs from patients with FPF.
31998366	0.95	PRC1, PBK).
31423162	0.94	PBK, PRC1, PTTG1, RRM2, TK1, TOP2A, TPX2, TYMS, UBE2C, UBE2T, UHRF1, ZWINT) and considered to be the most relevant genes for breast cancer.
26743006	0.91	PBK, NUSAP1, HMMR, CIT, ANLN, SKA3, BIRC5, PRC1) and the 6-gene Panel B (CREB1/FoxA1 downregulated genes identified in abl cells: AZGP1, CRISPLD2, EPHX2, HSPB8, PTRF, MFGE8).
	0.59	PBK, PRC1, SKA3 and UBE2C) and four of our previously identified CREB1/FoxA1 target genes (CCNA2, CCNE2, E2F1 and CDK1) for further analysis (Supplementary Figure S8B).
31822116	0.91	PBK, TOP2A, ASPM, HMMR, RRM2, CDKN3, PRC1, and ANLN were upregulated in HCC, and the survival rate was lower for HCC with increased expression of these hub genes.
	0.89	PBK, TOP2A, ASPM, HMMR, CDKN3, PRC1, and ANLN.
30855480	0.90	PBK/TOPK directly binds cdk1/cyclin B1 complex and then threonine-9 of PBK/TOPK is phosphorylated by cdk1/cyclin B1 complex which promotes cytokinesis through phosphorylation of a protein regulator of cytokinesis 1 (PRC1).
26081429	0.82	PBK/TOPK and cdk1/cyclin B1 complex promote cytokinesis through phosphorylation of a protein regulator of cytokinesis 1 (PRC1) and a positive feedback loop between PBK/TOPK and ERK2 promotes uncontrolled proliferation.