Publication for GLI1 and INHBE

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
hsa GLI1 GLI family zinc finger 1 2735 [link]
hsa INHBE inhibin subunit beta E 83729

Pubmed ID Priority Text
25654223 0.98 GLI1 than the INHBE gene.
0.94 GLI1AS is located head-to-head with the GLI1 gene and tail-to-tail with the INHBE gene.
23200667 0.98 Gli activators upregulate CCND1 and CCND2 for cell cycle acceleration, FOXA2, FOXC2, FOXE1, FOXF1, FOXL1, FOXP3, POU3F1, RUNX2, SOX13 and TBX2 for cell fate determination, and JAG2, INHBC and INHBE for stem cell signaling regulation.
24726458 0.97 INHBE is a GLI1 target gene.
0.97 INHBE down-regulation by GLI1AS overexpression (Figure 4E) is not an indirect result of the reduced GLI1 levels, rather an effect of the antisense RNA on the organization of the chromatin locus.
0.97 GLI1 and INHBE down-regulation by GLI1AS overexpression, chromatin immunoprecipitation assays on transfected Rh36 cells were performed.
0.92 GLI1 expression are gene specific, the mRNA levels of INHBE, a gene positioned tail-to-tail to GLI1AS (Supplementary Figures 3 and 4) and of an unrelated gene on chromosome 21q22.3, ADAR2, were also analyzed.
0.90 INHBE expression was reduced, albeit not to the same extent as to that seen for GLI1 (Figure 4E).
0.90 GLI1, with the major differences observed at the 5' end the INHBE, GLI1AS and GLI1 genes, segments A, E, and F (Supplementary Figure 9).
0.88 INHBE/GLI1AS/GLI1 genomic regions, being most pronounced at the 5' end of the INHBE and GLI1 genes, at interrogated segments A and F (Figure 5A).
30302195 0.97 INHBE with GLI1 (Table 1).
0.96 INHBE with GLI1.
0.95 GLI1 due to its fusion with the 5' end of INHBE, a highly expressed gene located upstream of GLI1.
29556382 0.97 INHBE, inhibin-betaE; GLI1, GLI family zinc finger 1; RT-qPCR, reverse transcription-quantitative polymerase chain reaction.
0.95 inhibin-betaE (INHBE)], metabolism [including pepsinogen 3 (PGA3) and alcohol dehydrogenase 1A] and differentiation [including troponin T type 1 (TNNT1), stimulator of chondrogenesis 1 (SCRG1), hairy/enhancer-of-split related with YRPW motif 1 and GLI family zinc finger 1 (GLI1)].
29350068 0.92 Inhibin Beta E Subunit (INHBE) producing a highly expressed INHBE_Glioma-associated oncogene family zinc finger 1 (GLI1) fusion protein leading to the constitutive activation of the sonic hedgehog pathway.



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