Publication for BUB1B and KIF18A

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
hsa BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 701 [link]
hsa KIF18A kinesin family member 18A 81930

Pubmed ID Priority Text
19625775 0.95 KIF18A, CENP-E and BubR1 given the known physical interaction between CENP-E and BubR1.
0.88 BubR1, KIF18A and alpha-tubulin.
0.83 KIF18A physically interacted with CENP-E and BubR1 during mitosis.
0.83 KIF18A, CENP-E or luciferase siRNAs for 24 h and were fixed and stained with antibodies to BubR1 (red) and alpha-tubulin (green).
0.80 KIF18A and CENP-E and between CENP-E and BubR1, it is conceivable that KIF18A can stabilize the CENP-E-BubR1 complex at the kinetochores during early mitosis.
0.80 KIF18A functions to provide the mitotic kinetochores with a constant flow of kinetochore proteins including CENP-E and BubR1.
0.76 KIF18A siRNA affected BubR1 subcellular localization.
0.75 BubR1 signals were significantly weakened in congressed kinetochores in cells transfected with KIF18A siRNA; the reduced BubR1 staining in centromeric kinetochores was also observed in cells transfected with CENP-E siRNA (Fig. 5C).
0.71 KIF18A, the CENP-E-BubR1 complex would be less stable at the kinetochores, especially the ones aligned at the metaphase plate.
0.64 BubR1 in control cells was about 18 h in cells transfected with luciferase siRNA; after depletion of KIF18A, the half-life of CENP-E was less than 8 h, significantly shorter than that in the control cells (Fig. 4).
30662724 0.94 KIF18A), mitotic checkpoint (BUB1B, MAD2L1), cell cycle transitions (CCNB1, PLK1, FOXM1, BIRC5, AURKA, CDC25A, MELK, CCNF), G1-phase progression (CDK4, E2F1) and cyclin degradation (CDC20, PTTG1).
25884224 0.83 BubR1 at anaphase and telophase stages, strongly suggesting that Kif18A sumoylation may regulate the removal of BubR1 from the kinetochores and compromise its inactivation.
29568567 0.71 BUB1B, CENPE, CCNB1, FBXO5, MAD2L1, DLGP5, ANAPC10, CDK1, BRCA2, NUSAP1, CENPF, ANLN, NDC80 and KIF18A belong to the most significant enriched GO terms.



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