Publication for BUB1B and KIF18A
| Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
|---|---|---|---|---|---|---|
| hsa | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | 701 | [link] | ||
| hsa | KIF18A | kinesin family member 18A | 81930 |
| Pubmed ID | Priority | Text |
|---|---|---|
| 19625775 | 0.95 | KIF18A, CENP-E and BubR1 given the known physical interaction between CENP-E and BubR1. |
| 0.88 | BubR1, KIF18A and alpha-tubulin. | |
| 0.83 | KIF18A physically interacted with CENP-E and BubR1 during mitosis. | |
| 0.83 | KIF18A, CENP-E or luciferase siRNAs for 24 h and were fixed and stained with antibodies to BubR1 (red) and alpha-tubulin (green). | |
| 0.80 | KIF18A and CENP-E and between CENP-E and BubR1, it is conceivable that KIF18A can stabilize the CENP-E-BubR1 complex at the kinetochores during early mitosis. | |
| 0.80 | KIF18A functions to provide the mitotic kinetochores with a constant flow of kinetochore proteins including CENP-E and BubR1. | |
| 0.76 | KIF18A siRNA affected BubR1 subcellular localization. | |
| 0.75 | BubR1 signals were significantly weakened in congressed kinetochores in cells transfected with KIF18A siRNA; the reduced BubR1 staining in centromeric kinetochores was also observed in cells transfected with CENP-E siRNA (Fig. 5C). | |
| 0.71 | KIF18A, the CENP-E-BubR1 complex would be less stable at the kinetochores, especially the ones aligned at the metaphase plate. | |
| 0.64 | BubR1 in control cells was about 18 h in cells transfected with luciferase siRNA; after depletion of KIF18A, the half-life of CENP-E was less than 8 h, significantly shorter than that in the control cells (Fig. 4). | |
| 30662724 | 0.94 | KIF18A), mitotic checkpoint (BUB1B, MAD2L1), cell cycle transitions (CCNB1, PLK1, FOXM1, BIRC5, AURKA, CDC25A, MELK, CCNF), G1-phase progression (CDK4, E2F1) and cyclin degradation (CDC20, PTTG1). |
| 25884224 | 0.83 | BubR1 at anaphase and telophase stages, strongly suggesting that Kif18A sumoylation may regulate the removal of BubR1 from the kinetochores and compromise its inactivation. |
| 29568567 | 0.71 | BUB1B, CENPE, CCNB1, FBXO5, MAD2L1, DLGP5, ANAPC10, CDK1, BRCA2, NUSAP1, CENPF, ANLN, NDC80 and KIF18A belong to the most significant enriched GO terms. |
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