Publication for DEPDC1 and KIF18A

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
hsa DEPDC1 DEP domain containing 1 55635 [link]
hsa KIF18A kinesin family member 18A 81930

Pubmed ID Priority Text
26295306 0.98 DEPDC1, CDC6, DLG7, KIF18A, EZH2, and HMMR) in GSCs, but also in the range of independent methods used to verify the results.
0.97 KIF18A, EZH2, DEPDC1, HMMR) and the two genes from cluster III, (NOL4 and RAPGEF4) were highly expressed in the majority of proneural samples.
0.97 KIF18A, EZH2, DEPDC1, HMMR, FILIP1L and FNDC3B) (Supplementary Table S2).
0.97 DEPDC1, CDC6, DLG7, KIF18A, EZH2, HMMR, NOL4, MPP6, MDM1, FNDC3B, FILIP1L, ATXN7L4, P2RY5 and FAM118A), we found good correlation (r = 0.64 + 021) between the RNA and the corresponding protein levels (Table 1).
0.97 DEPDC1, NOL4, CDC6, KIF15, MPP6, KIF18A, EZH2, HMMR, FAM118A, FNDC3B and MDM1.
0.97 DEPDC1, KIF15, KIF18A and DLG7 were all interconnected via ubiquitin C (UBC).
0.96 DEPDC1, NOL4, CDC6, KIF15, MPP6, KIF18A, EZH2, HMMR, FAM118A, FNDC3B and MDM1 (Figure 5A, Supplementary Figure S7).
0.95 DEPDC1, CDC6, DLG7/DLGAP5/HURP, KIF18A, EZH2, HMMR/RHAMM/CD168, NOL4, MPP6, MDM1, RAPGEF4, RHBDD1, FNDC3B, FILIP1L, MCC, ATXN7L4/ATXN7L1, P2RY5/LPAR6 and FAM118A (Figure 1A, Table 1 and Supplementary Figure S1).
0.95 KIF18A, EZH2, DEPDC1 and HMMR), the second eight genes (FILIP1L, MCC, MPP6, ATXN7L4, P2RY5, FAM118A, FNDC3B and MADM1), and the third two genes (NOL4, RAPGEF4) (Figure 3A).
0.94 KIF18A, EZH2, DEPDC1, HMMR, P2RY5, FAM118A, and FNDC3B) correlated with the least favorable survival (Supplementary Figure S6A).
0.94 KIF18A, DEPDC1, KIF15, NOL4 and FAM118A from protein cluster 1 positively correlated with the increment in levels of MTOR, DLL3 (Notch), PDGFB and STAT3.
0.94 KIF18A and EZH2 shared common interactants with DLL3 and that DLG7, DEPDC1 and CENPA shared common interactants with STAT3.
0.90 DEPDC1, CDC6, DLG7, KIF18A, EZH2, and HMMR) were all part of the same protein-protein interaction network (Figure 6).
0.89 DEPDC1, CDC6, DLG7, KIF18A, EZH2, HMMR, NOL4, MCC, MPP6, RAPGEF4, ATXN7L4 and MDM1) were significantly up-regulated while FAM118A and P2RY5 were down-regulated (Figure 1C-1C').
0.87 DEPDC1, CDC6, DLG7/DLGAP5/HURP, KIF18A, EZH2, HMMR/RHAMM/CD168, NOL4, MPP6, MDM1, RAPGEF4, RHBDD1, FNDC3B, FILIP1L, MCC, ATXN7L4/ATXN7L1, P2RY5/LPAR6 and FAM118A) that were consistently expressed in GSC cultures and consistently not expressed in NSC cultures.
0.87 DEPDC1, CDC6, DLG7, KIF18A, EZH2, HMMR, MPP6, RHBDD1 and FNDC3B (Figure 6, Supplementary Figures S8-S9) as well as with products of BMI1, MTOR, STAT3, HIF1A, EGFR, NF1, POU3F2 and SALL2.
0.85 KIF18A, EZH2, DEPDC1 and HMMR (red text) were highly co-expressed in all four subtypes.
0.80 DEPDC1, CDC6, DLG7, KIF18A, EZH2, and HMMR) whose expression was confirmed using all experimental and bioinformatics verification methods (Table 1).
30662724 0.98 KIF18A (p = 0.0061), DEPDC1 (p = 0.0092), CCNF (p = 0.019), SLC2A1 (p = 0.036) and WASF2 (p = 0.048).
32063710 0.94 KIF18A, KNSTRN, ANLN, NEIL3, KIF23, HELLS, E2F7, DEPDC1, ERCC6L, PARPBP, and FBXO5), as shown in Figure 1C.



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