Publication for KIF20A and KIF18A

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
hsa KIF20A kinesin family member 20A 10112 [link]
hsa KIF18A kinesin family member 18A 81930

Pubmed ID Priority Text
32322170 1.00 KIF18A, KIF18B, KIF20A, KIF20B, KIF23, KIF4A and KIFC1 with significantly high expression in Basal-like and Luminal B subtypes comparing to Luminal A breast cancer (Fig. 1a, Additional file 3).
0.96 KIF18A, KIF18B, KIF20A, KIF4A were included (Fig. 3b) and a 6-KIFs-based risk score was generated as below:
0.96 KIF18A), Paprotrain (the first known inhibitor of MKLP2).
0.95 KIF18A, KIF18B, KIF20A, KIF23, KIF2C, KIF4A, KIFC1) significantly correlated with worse OS, RFS and DMFS of breast cancer, indicating efficient biomarkers for predicting the prognosis of breast cancer.
0.94 KIF18A, KIF18B, KIF20A, KIF4A) identified by LASSO regression regarding RFS, OS and DMFS (Additional file 5).
0.94 KIF18A: P = 0.0003; KIF20A: P = 0.0022), which in accordance with bioinformatics results (Fig. 4a).
0.93 KIF18A, KIF18B, KIF20A, KIF23, KIF2C, KIF4A, KIFC1) significantly correlated with worse OS, relapse-free survival (RFS) and distant metastasis-free survival (DMFS) of breast cancer.
0.91 KIF18A, KIF18B, KIF20A, KIF4A) were testified by quantitative RT-PCR and immunohistochemistry.
0.86 KIF18A, KIF18B, KIF20A, KIF20B, KIF22, KIF23, KIF24, KIF26B, KIF2C, KIF3B, KIF4A, KIFC1) overexpressed.
0.85 KIF18A, KIF18B, KIF20A, KIF23, KIF2C, KIF4A, KIFC1).
0.55 KIF18A, KIF18B, KIF20A, KIF23, KIF2C, KIF4A, KIFC1) that demonstrated significant prognostic value in breast cancer were enrolled for LASSO regression to construct a KIFs-based risk score for prediction of OS in breast cancer.
24391143 0.97 Kif18A/18B, Kif20A/20B, Kif21, Kif23, Kif24, Kif25 and KifC1 while suppresses the expression of 7 others including Kif1A, Kif1C, Kif7 and KifC3.
0.62 Kif18A, Kif20A, and Kif23), Kif3B is primarily involved in cell migration and Kif24 is a centriolar kinesin and functions to remodel the local microtubules for cilia assembly.
22235336 0.96 KIF20A, CDCA3, PTTG1, UBE2C, AURKA, DLGAP5, and KIF18A (Figure S2).
28789343 0.96 KIF20A, centromere protein E (CENPE), KIF2C, KIF3A, KIFAP3, KIF4A, rac GTPase activating protein 1 (RACGAP1), KIF2A, KIF3C, kinesin light chain 1 (KLC1), KIF5A, kinesin light chain 2 (KLC2), KIF5B, KIF5C, KIF11, KIFC1, KIF22, KIF15, KIF18A, KIF3B and KIF23, of which KIF20A and KIF11 were common genes.
30906836 0.92 KIF18A, KIF2C, CENPE, CENPF, CENPK, KIF20A, CCNB1 are the genes found in the top cluster with high interaction.
31324769 0.92 Kif20a and Kif18a (Fig. 5a). Kinesin-1 is a heterotetramer consisting of a kinesin heavy chain (Kif5) and kinesin light chain (KLC) homodimer.
30813560 0.88 KIF18A, KIF18B, KIF20A and KIF23, and this led us to focus on kinesins in subsequent studies for the molecular mechanism of lactate-driven cell motility (see below).
21390237 0.87 Kif18a, Kif22, Kif4), segregation (Aspm Cenpe, Ckap2, Incenp, Jub, Kif20a, Kif23, Lats2, Prc1), and/or cytokinesis (Incenp, Kif20a, Kif23, Prc1) (Table 4).
29346445 0.86 KIF18A, KIF20A, which play a pivotal role in cell movements and intracellular trafficking, including chromosome and centrosome positioning during mitosis.
0.73 KIF20A, KIF2C, KIF4A, KIF18A, KIF11, and KIF15 (Fig 2C).
30593585 0.86 KIF20A (E), KIF23 (F), KIF11 (G), KIF14 (H), KIF15 (I), KIF18A (J), and KIF26B (K).
28099485 0.82 KIF18A, KIF20A, KIF23) modulated by AS03 at day 3 in NK more likely play a role in cell division, as multiple modules of proliferation- and cell division-related genes were identified in this cell type at this time point.
24386490 0.81 KIF18A, KIF20A, and KIF20B were up-regulated in several malignancies and associated with tumoral progression.
25264741 0.54 KIF20A expression change, microarray data of RB/E2F regulatory G2/M-related eight genes, CENPE, CDC25C, CDCA8, KIF11, ECT2, NEK2, CCNA2, KIF18A, were shown in Table 2.



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