Publication for Slitrk5 and Slitrk1
| Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
|---|---|---|---|---|---|---|
| mmu | Slitrk5 | SLIT and NTRK-like family, member 5 | 75409 | [link] | ||
| mmu | Slitrk1 | SLIT and NTRK-like family, member 1 | 76965 |
| Pubmed ID | Priority | Text |
|---|---|---|
| 21315458 | 0.98 | Slitrk1 overexpression in neurons and the analyses of the Slitrk5 and 6 null mice, suggest that multiple Slitrk members play key roles in promoting neurite outgrowth. |
| 0.94 | Slitrk5 had the broadest expression amongst the various tumors analyzed, whereas gliomas mainly express Slitrk1-3. | |
| 0.92 | Slitrk1 mRNA expression was highest in the frontal lobe and Slitrk5 was expressed in both occipital and frontal lobes. | |
| 0.53 | Slitrk1, Slitrk5 and SAPAP3 knockout mice. | |
| 22286174 | 0.97 | Slitrk5-/- mice have impaired corticostriatal synaptic transmission with altered postsynaptic composition of glutamate receptors and Slitrk1-/- mice have elevated anxiety-like behavior supports the idea that multiple Slitrk family members may participate in inhibitory and/or excitatory synapse development. |
| 20418887 | 0.96 | Slitrk1 gene belongs to a new family of six members (Slitrk1-Slitrk6) encoding one-pass transmembrane proteins that contain two extracellular leucine-rich repeat domains, similar to Slit proteins, and a carboxy-terminal domain that is similar to Trk neurotrophin receptors. |
| 0.85 | Slitrk5 may lead to behavioral phenotypes similar to the involvement of SLITRK1 in Tourette's syndrome. | |
| 19936227 | 0.96 | Slitrk1 through Slitrk5 are expressed broadly throughout the brain, the expression of Slitrk6 is highly restricted to thalamic nuclei. |
| 21605970 | 0.96 | Slitrk1 and Slitrk5 may point to a common pathway to neuropsychiatric disorders through disruption of Slitrk gene function in the CNS. |
| 31745231 | 0.96 | Slitrk1, Slitrk4 and Slitrk5) may differentially compensate for the effect of Slitrk2 loss. |
| 27273464 | 0.91 | Slitrk1 leads to increased anxiety-like behaviour, Slitrk5 mutant mice display obsessive compulsive-like behaviors, and Slitrk3 mutant mice exhibit increased susceptibility to seizures. |
| 24821223 | 0.77 | SLITRK5 and SLITRK1, have been shown to be associated with TS and OCD, the former in a mouse model and the latter in a TS genetic study . |
| 27646291 | 0.50 | SLITRK1 should be seen as contributing to construct validity of Slitrk5 null mice as a model of OC-spectrum behavior. |
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