Publication for UBE2K and UBE2V2

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
hsa	UBE2K	ubiquitin conjugating enzyme E2 K	3093			[link]
hsa	UBE2V2	ubiquitin conjugating enzyme E2 V2	7336

Pubmed ID	Priority	Text
18179693	0.97	Mms2 and Ube2k as ubiquitin-specific E2s for BRCA1 and classified UbcH6, Ube2e2, UbcM2 and Ube2w as substrate-specific E2s for BRCA1.
	0.96	Mms2 or Ube2k, in the presence of substrate-specific E2s, such as Ube2w, resulted in K63-linked or K48-linked polyubiquitin chains, respectively, in addition to K6-linked polyubiquitin chains mediated by UbcH5.
29725124	0.97	E2-25K, kUb2, is 0.002 s-1, comparable to the value of 0.007 s-1 for catalysis of K63-Ub2 synthesis by the Mms2/Ubc13 protein complex.
	0.97	Mms2 with Ub conjugated to the active site and bound to the underside of Ubc13, whereas E2-25K generally adopts the catalytically active, closed conformation.
31877708	0.97	UBE2V2, UBE2K, and UBE2D3; cluster IV with EIF3G, TUFM, RPLP0, RPLP2, and ABCE1; cluster V with ATP1B1, ATP1A3, ATP1B3, and ATP1B3; cluster VI with ECHS1, HSD17B10, HADH, and ALDH2; cluster VII with CYCS, LCP1, ACTC1, ACTA2, ACTG2, CTTN, and GSN; and cluster VIII with RAB25, RAB2B, RAB11A, SEC22B, COPG1, COPG2, CD59, DYNC1I2, DYNLL1, RAB1A, and RAB6A.
22196026	0.95	E2-25K (also known as UbcH1 or UBE2K), K63-specific Ubc13/Mms2, and K11-specific UBE2S.
	0.94	E2-25K was replaced with a heterodimeric complex consisting of Ubc13 and Mms2, an E2 enzyme and an E2 variant (UEV) lacking the active site cysteine normally present in an E2.
25436519	0.92	MMS2 or Ube2k.
21281599	0.86	E2-25K mimics the presence of the non-catalytic E2 in a heterodimeric complex such as Mms2/Ubc13, which synthesizes free Lys63-linked polyubiquitin chains.
19560420	0.72	Ubc1-Ub, which forms K48 ubiquitin chains and Ubc13-MMs2-Ub, which forms K63 chains (Deng et al., 2000), (Figure 3B) reveals that the C-termini of either of the two bound ubiquitins can readily be accommodated in the channel surrounding C89.
22162729	0.64	MMS2), Lys48 (UBE2K), or Lys6 (UBCH5) linkages.
31120930	0.52	Ube2k as well as Ube2n/Ube2v2 to form K48- or K63-linked ubiquitin chains, respectively.