Publication for Treml1 and Treml2

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
mmu Treml1 triggering receptor expressed on myeloid cells-like 1 71326 [link]
mmu Treml2 triggering receptor expressed on myeloid cells-like 2 328833

Pubmed ID Priority Text
26557807 0.98 TREML-1 and TREML-2, which encode TLT-1 and TLT-2, respectively, contain a cytoplasmic tail with immunoreceptor tyrosin inhibitory motifs (ITIMs) that can associate with the SHP-1 and SHP-2 proteins.
0.96 TREML-1 and TREML-2, contained two ITIMs domains in the cytoplasmic tail, which has been shown to recruit SHP-2 protein, but not the SHIP protein.
21804015 0.98 TLT1, TLT2 does not contain an ITAM or ITIM in its cytoplasmic domain, which have the ability to recruit SH2 domain-containing effector proteins to mediate signal transduction.
24453980 0.96 TLT-1 and TLT-2 have been described, TREM-1 is the first identified and best characterized receptor of the TREM family with activating functions.
19426220 0.93 TLT-1, TLT-2 is not associated with DAP12 for signaling, as was predicted by the absence of charged amino acids in the transmembrane domain.
29518357 0.93 TREML1, TREML2, and TREML4, which likely serve critical innate immune functions, their overexpression may confound the interpretation of TREM2 gene dosage studies in vivo.
27143430 0.91 TREML1, and TREML2, have direct homologs in mice and humans.
25363248 0.86 TLT-1, TLT-2 and TREM-2 were found to bind with low affinity to lipids including phosphatidic acid, cardiolipin, and lipid A, whereas TREM-1 and TREM-3 did not.
0.85 TLT-1 and TLT-2, unlike TREM-1 and TREM-2, do not associate with the adaptor protein DAP12 (see Figure 2).
0.77 TLT-1 and TLT-2 in maladies ranging from acute and chronic inflammatory disorders to cardiovascular diseases and cancers are discussed.
25131209 0.85 Treml1, D3ZDX3_Rat, and Treml2 resulted in a weaker and variable downregulation of the network genes (Figure 2C).
0.76 Treml1, D3ZDX3_Rat, Treml2, and each trans-eQTL gene expression (Figure 2B).
0.70 Treml1, Trem2, D3ZDX3_Rat, and Treml2 genes that were differentially expressed between WKY and LEW macrophages (Figure 1F), followed by quantitative real-time PCR assessment of ten trans-regulated genes from the network.
29027827 0.76 TREM-like transcript 1 (TLT-1) and TLT-2.



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