Publication for Treml1 and Treml2
| Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
|---|---|---|---|---|---|---|
| mmu | Treml1 | triggering receptor expressed on myeloid cells-like 1 | 71326 | [link] | ||
| mmu | Treml2 | triggering receptor expressed on myeloid cells-like 2 | 328833 |
| Pubmed ID | Priority | Text |
|---|---|---|
| 26557807 | 0.98 | TREML-1 and TREML-2, which encode TLT-1 and TLT-2, respectively, contain a cytoplasmic tail with immunoreceptor tyrosin inhibitory motifs (ITIMs) that can associate with the SHP-1 and SHP-2 proteins. |
| 0.96 | TREML-1 and TREML-2, contained two ITIMs domains in the cytoplasmic tail, which has been shown to recruit SHP-2 protein, but not the SHIP protein. | |
| 21804015 | 0.98 | TLT1, TLT2 does not contain an ITAM or ITIM in its cytoplasmic domain, which have the ability to recruit SH2 domain-containing effector proteins to mediate signal transduction. |
| 24453980 | 0.96 | TLT-1 and TLT-2 have been described, TREM-1 is the first identified and best characterized receptor of the TREM family with activating functions. |
| 19426220 | 0.93 | TLT-1, TLT-2 is not associated with DAP12 for signaling, as was predicted by the absence of charged amino acids in the transmembrane domain. |
| 29518357 | 0.93 | TREML1, TREML2, and TREML4, which likely serve critical innate immune functions, their overexpression may confound the interpretation of TREM2 gene dosage studies in vivo. |
| 27143430 | 0.91 | TREML1, and TREML2, have direct homologs in mice and humans. |
| 25363248 | 0.86 | TLT-1, TLT-2 and TREM-2 were found to bind with low affinity to lipids including phosphatidic acid, cardiolipin, and lipid A, whereas TREM-1 and TREM-3 did not. |
| 0.85 | TLT-1 and TLT-2, unlike TREM-1 and TREM-2, do not associate with the adaptor protein DAP12 (see Figure 2). | |
| 0.77 | TLT-1 and TLT-2 in maladies ranging from acute and chronic inflammatory disorders to cardiovascular diseases and cancers are discussed. | |
| 25131209 | 0.85 | Treml1, D3ZDX3_Rat, and Treml2 resulted in a weaker and variable downregulation of the network genes (Figure 2C). |
| 0.76 | Treml1, D3ZDX3_Rat, Treml2, and each trans-eQTL gene expression (Figure 2B). | |
| 0.70 | Treml1, Trem2, D3ZDX3_Rat, and Treml2 genes that were differentially expressed between WKY and LEW macrophages (Figure 1F), followed by quantitative real-time PCR assessment of ten trans-regulated genes from the network. | |
| 29027827 | 0.76 | TREM-like transcript 1 (TLT-1) and TLT-2. |
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