Publication for STAT1 and APOL6

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
hsa STAT1 signal transducer and activator of transcription 1 6772 [link]
hsa APOL6 apolipoprotein L6 80830

Pubmed ID Priority Text
30260027 0.98 APOL6; CXCL10; GBP family members (GBP-1, -2, -4 and -5); HAPLN3; IRF1; LGALS3BP; STAT1; TAP1; WARS and WDFY1.
0.84 APOL6, CXCL10, HAPLN3, IRF1, LGALS3BP, STAT1, TAP1, WDFY1 and genes of the GBP family members GBP-1, -2, -4 and -5.
24846384 0.96 STAT1 GAS motifs (TTC[N 2-4]GAA) within 1 kb of the translational start site and 200 bp downstream; the number of these motifs varied by gene (CXCL10 [2], IFIT1 [1], CFHR1 [1], APOL6 [1]) but did not dictate expression of STAT1.
0.85 APOL6, ISGs with decreased expression, had no increase in STAT1 binding despite the presence of activated STAT1 in those cells.
0.77 STAT1 (Santa Cruz) followed by qPCR of the 5'UTR of upregulated genes CXCL10 and IFIT1 or downregulated genes CFHR1 and APOL6 in the context of H5N1-VN1203 infection.
32139709 0.92 APOL6 appears to be associated with the STAT1 pathway, and indeed, APOL6 expression was strongly correlated with STAT1 in colon cancer (Spearman's rank correlation 0.67, p-value 7.99e-54) and all other cancers with expression datasets greater than 400 patients after adjusting for tumor purity (Supplementary Table 4).
0.71 APOL6, and many of the other proteins, were not shown as connected to the STAT1 pathway.
24587128 0.62 APOL6, STAT2, STAT1, LOC653610, GK, DHRS9, TRAFD1, UBE2L6, GBP2, LPCAT2, AK026751, ASPHD2, BRSK1, and FLVCR2).



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